Lake Nona Medical City 5 Stars Hotels

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Check availability on Lake Nona Medical City 5 Star Hotels

Tonight
Dec 7 - Dec 8
Tomorrow
Dec 8 - Dec 9
Next weekend
Dec 12 - Dec 14
In two weeks
Dec 19 - Dec 21

Compare Lake Nona Medical City 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Exterior
Waldorf Astoria Orlando - An Official Walt Disney World® Hotel

Waldorf Astoria Orlando - An Official Walt Disney World® Hotel

5.0 star property
Orlando
9.2 out of 10, Wonderful, (415)
"Excellent dining and stay"
Canada
RAJ
The price is NT$10,221
NT$13,256 total
includes taxes & fees
Jan 4 - 2026/1/5
Waldorf Astoria Orlando - An Official Walt Disney World® Hotel
Outdoor pool, cabanas (surcharge), pool umbrellas
Conrad Orlando at Evermore

Conrad Orlando at Evermore

5.0 star property
Orlando
9.6 out of 10, Exceptional, (336)
"Place was freaking amazing!"
United States
Shaun
The price is NT$14,578
NT$17,962 total
includes taxes & fees
Dec 14 - Dec 15
Conrad Orlando at Evermore
3 outdoor pools, cabanas (surcharge), pool umbrellas
Four Seasons Resort Orlando at WALT DISNEY WORLD® Resort

Four Seasons Resort Orlando at WALT DISNEY WORLD® Resort

5.0 star property
Golden Oak
9.6 out of 10, Exceptional, (878)
"Fantastic hotel, lovely front desk and housekeeping staff. "
United States
Tanis
The price is NT$37,331
NT$43,754 total
includes taxes & fees
Dec 9 - Dec 10
Four Seasons Resort Orlando at WALT DISNEY WORLD® Resort
View from property
The Ritz-Carlton Orlando, Grande Lakes

The Ritz-Carlton Orlando, Grande Lakes

5.0 star property
Orlando
9.2 out of 10, Wonderful, (1000)
"Great service, clean rooms, large property with many amenities . Fabulous food at highball & harvest. "
United States
SAUL
The price is NT$19,962
NT$24,390 total
includes taxes & fees
Jan 1 - 2026/1/2
The Ritz-Carlton Orlando, Grande Lakes
Outdoor pool, open 9:00 AM to 6:00 PM, free cabanas, pool umbrellas
ette hotel

ette hotel

5.0 star property
Kissimmee
9.8 out of 10, Exceptional, (373)
"If you're looking to stay at hotel with all the top amenities, great staff and amazing restaurant at a very nice price...this is the spot! Location is a bit busy but all is made up quality inside the hotel. "
United States
michael
The price is NT$11,668
NT$13,243 total
includes taxes & fees
Dec 14 - Dec 15
ette hotel
Outdoor pool, a heated pool, cabanas (surcharge), pool umbrellas
Encore Resort and Water Park at Reunion by Rentyl

Encore Resort and Water Park at Reunion by Rentyl

5.0 star property
Kissimmee
8.4 out of 10, Very Good, (1001)
"Beautiful and inviting. "
United States
Margie
The price is NT$7,779
NT$22,302 total
includes taxes & fees
Dec 9 - Dec 10
Encore Resort and Water Park at Reunion by Rentyl
Exterior
Reunion Resort & Golf Club

Reunion Resort & Golf Club

5.0 star property
Reunion
8.8 out of 10, Excellent, (1436)
"Family Friendly"
United States
Janaya
The price is NT$7,304
NT$9,770 total
includes taxes & fees
Dec 9 - Dec 10
Reunion Resort & Golf Club
3 outdoor pools
Disney's Beach Club Resort

Disney's Beach Club Resort

5.0 star property
Bay Lake
8.8 out of 10, Excellent, (696)
"Location location location!! Best pool!!"
United States
Seung Hoon
Disney's Beach Club Resort
Aerial view
Gorgeous Two Bedroom Apt Close to Disney 306 4721 @Storey Lake Resort

Gorgeous Two Bedroom Apt Close to Disney 306 4721 @Storey Lake Resort

5.0 star property
Kissimmee
8.4 out of 10, Very Good, (10)
"The complex was nice and very nice clean rooms, the water park was nice and huge. Definitely would visit again "
United States
Vernon
Gorgeous Two Bedroom Apt Close to Disney 306 4721 @Storey Lake Resort
Water park
Gorgeous 2Bd Apto Close to Disney @ Storey Lake 404 3191

Gorgeous 2Bd Apto Close to Disney @ Storey Lake 404 3191

5.0 star property
Kissimmee
10.0 out of 10, Exceptional, (3)
"Fabulous apartment, great equipment as excellent location! We stayed for 11 nights in October visiting Disney 10 days and Kennedy Space Centre for a days. Parking was easy and there is a decent gym and nice water park on site. Flawless communiction throughout our stay. Would definately stay again!"
United Kingdom
Dean
Gorgeous 2Bd Apto Close to Disney @ Storey Lake 404 3191
Exterior
Stunning 2 Bd Condo Close to Disney 304 3191

Stunning 2 Bd Condo Close to Disney 304 3191

5.0 star property
Kissimmee
6.6 out of 10, (4)
"The Place Awesome it was a family trip we had great time my 2 kids love the Pool, the Lazy river. they love the hold place. places are not far from Condo. Great communication they always was checking if we needed anything it was great. Thank You "
United States
Gema
Stunning 2 Bd Condo Close to Disney 304 3191
2 outdoor pools, free cabanas, pool umbrellas
Luxurious 2 Bd Close to Disney @ Storey Lake 204 3131

Luxurious 2 Bd Close to Disney @ Storey Lake 204 3131

5.0 star property
Kissimmee
10.0 out of 10, Exceptional, (4)
"It was a clean and nice "
United States
Danielle
Luxurious 2 Bd Close to Disney @ Storey Lake 204 3131
Townhome, 4 Bedrooms | Private pool
Gorgeous 4 Bedroom w/ Pool Close to Disney 4836

Gorgeous 4 Bedroom w/ Pool Close to Disney 4836

5.0 star property
Kissimmee
9.2 out of 10, Wonderful, (13)
"Super clean and confortable. "
United States
Heralda
Gorgeous 4 Bedroom w/ Pool Close to Disney 4836
Water park
Gorgeous 4Bd with Pool @ Storey Lake Resort 4475

Gorgeous 4Bd with Pool @ Storey Lake Resort 4475

5.0 star property
Kissimmee
9.0 out of 10, Wonderful, (4)
Gorgeous 4Bd with Pool @ Storey Lake Resort 4475
Luxury Villa, Multiple Bedrooms, Private Pool | Courtyard view
7 Bedroom Villa, Private Pool, Resort Amenities

7 Bedroom Villa, Private Pool, Resort Amenities

5.0 star property
Kissimmee
9.0 out of 10, Wonderful, (15)
"Beautiful and the family loved it 😍! Close to Disney, excellent for large families"
Canada
LLoyd
7 Bedroom Villa, Private Pool, Resort Amenities
Water park
Splendid 5Bd Close to Disney at Storey Lake 4251

Splendid 5Bd Close to Disney at Storey Lake 4251

5.0 star property
Kissimmee
9.2 out of 10, Wonderful, (12)
"Home was great super clean and very cozy and comfortable. "
United States
Ubeiman
Splendid 5Bd Close to Disney at Storey Lake 4251
Water park
Marvelous 4Bd with Pool at Storey Lake Resort 2601

Marvelous 4Bd with Pool at Storey Lake Resort 2601

5.0 star property
Kissimmee
10.0 out of 10, Exceptional, (2)
Marvelous 4Bd with Pool at Storey Lake Resort 2601
Townhome, 5 Bedrooms | Living area | 60-inch Smart TV with cable channels, TV, Netflix
Family Friendly 5 Bedrooms Home Close to Disney 4849

Family Friendly 5 Bedrooms Home Close to Disney 4849

5.0 star property
Kissimmee
8.8 out of 10, Excellent, (3)
"Everything was well clean and very easy access"
United States
Raquel
Family Friendly 5 Bedrooms Home Close to Disney 4849
Indoor pool, outdoor pool, sun loungers, lifeguards on site
5 Bedroom Single Family @ Storey Lake Resort Close to Disney 4759

5 Bedroom Single Family @ Storey Lake Resort Close to Disney 4759

5.0 star property
Kissimmee
10.0 out of 10, Exceptional, (2)
"Me encantó la propiedad, la comunicación que tuvieron conmigo en todo momento y el precio! Super recomendada!!! "
Mexico
Patricia
5 Bedroom Single Family @ Storey Lake Resort Close to Disney 4759
Exclusive House | Private pool
Marvelous 5Bd w/ Pool Close to Disney @ Storey Lake 2629

Marvelous 5Bd w/ Pool Close to Disney @ Storey Lake 2629

5.0 star property
Kissimmee
8.8 out of 10, Excellent, (3)
"Nice "
United States
Janismarie
Marvelous 5Bd w/ Pool Close to Disney @ Storey Lake 2629
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Lake Nona Medical City.
DoubleTree by Hilton at the Entrance to Universal Orlando

DoubleTree by Hilton at the Entrance to Universal Orlando

5780 Major Blvd Orlando FL
The price is NT$2,792 per night from Dec 15 to Dec 16
NT$2,792
NT$3,141 total
Dec 15 - Dec 16
includes taxes & fees
8.4/10 Very Good! (6,876 reviews)
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Frequently asked questions

How much does it cost to stay in a 5-star hotel in Lake Nona Medical City?
You can find a variety of pricing options for 5-star hotels in Lake Nona Medical City on Expedia. The amount you pay will depend on when you plan to travel, length of stay and other factors. Compare available accommodations for your desired dates and use our pricing and other filters to score the ideal upscale stay.

  • Search for the lowest price per night from NT$3,141

What makes a hotel 5 stars in Lake Nona Medical City?
Flawless guest service is the foundation of every 5-star hotel in Lake Nona Medical City. From the minute you arrive, staff attend to your every whim, whether arranging customized tours or providing in-room beauty treatments. Also, hotels have to feature upscale amenities to obtain a 5-star rating. These can include luxury bathrobes, on-site spa facilities, pools, gourmet kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Lake Nona Medical City?
Use our convenient filters to find a high-end escape in Lake Nona Medical City where most of what you need is included in the price. From there, narrow your results for accommodations that have 5 stars and are listed as "All inclusive." The most important thing on the to-do list at these stays? Pure enjoyment and indulgence.

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