Lake Nona Medical City 4 Stars Hotels

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Our top choices for Lake Nona Medical City 4-star hotels

DoubleTree by Hilton at the Entrance to Universal Orlando

DoubleTree by Hilton at the Entrance to Universal Orlando
4.0 star property
Florida Center
8.4 out of 10, Very Good, (6874)
"Wonderful stay. Great location!"
United States
Charmaine
The price is NT$3,059
NT$3,442 total
includes taxes & fees
Dec 15 - Dec 16
DoubleTree by Hilton at the Entrance to Universal Orlando

Hyatt Regency Orlando International Airport

Hyatt Regency Orlando International Airport
4.0 star property
Orlando
9.4 out of 10, Exceptional, (3817)
"Clean room, quiet, love staying right at the airport."
United States
Tera
The price is NT$5,082
NT$5,717 total
includes taxes & fees
Dec 24 - Dec 25
Hyatt Regency Orlando International Airport

Hyatt Regency Orlando

Hyatt Regency Orlando
4.5 star property
International Drive District
9.2 out of 10, Wonderful, (1864)
"Clean and beautifully maintained hotel . "
United States
Puneet
The price is NT$3,949
NT$6,171 total
includes taxes & fees
Dec 23 - Dec 24
Hyatt Regency Orlando

Walt Disney World Dolphin

Walt Disney World Dolphin
4.0 star property
Bay Lake
8.8 out of 10, Excellent, (3988)
"Great place to stay"
United States
Steven
The price is NT$7,379
NT$9,862 total
includes taxes & fees
Dec 18 - Dec 19
Walt Disney World Dolphin

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
4.0 star property
Orlando
9.4 out of 10, Exceptional, (4074)
"Beautiful resort"
United States
Antonese
The price is NT$3,467
NT$3,901 total
includes taxes & fees
Jan 5 - 2026/1/6
Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

Hilton Orlando Lake Buena Vista - Disney Springs® Area

Hilton Orlando Lake Buena Vista - Disney Springs® Area
4.0 star property
Lake Buena Vista
8.6 out of 10, Excellent, (1447)
"Great location "
United States
Vivian
The price is NT$4,218
NT$6,114 total
includes taxes & fees
Dec 21 - Dec 22
Hilton Orlando Lake Buena Vista - Disney Springs® Area

DoubleTree by Hilton Hotel Orlando at SeaWorld

DoubleTree by Hilton Hotel Orlando at SeaWorld
4.0 star property
International Drive District
7.6 out of 10, Good, (6230)
"Great location friendly staff"
United States
Sherell Henley
The price is NT$2,049
NT$3,183 total
includes taxes & fees
Dec 18 - Dec 19
DoubleTree by Hilton Hotel Orlando at SeaWorld

Sheraton Vistana Villages Resort Villas, I-Drive/Orlando

Sheraton Vistana Villages Resort Villas, I-Drive/Orlando
4.0 star property
International Drive District
9.2 out of 10, Wonderful, (2724)
"Stayed here before always enjoyed it "
United States
Margaret
The price is NT$2,993
NT$3,368 total
includes taxes & fees
Jan 5 - 2026/1/6
Sheraton Vistana Villages Resort Villas, I-Drive/Orlando

Courtyard by Marriott Lake Buena Vista at Vista Centre

Courtyard by Marriott Lake Buena Vista at Vista Centre
4.0 star property
Orlando
8.2 out of 10, Very Good, (1408)
"Staff very friendly Hotel clean and organized "
United States
Steven
The price is NT$2,463
NT$3,122 total
includes taxes & fees
Dec 15 - Dec 16
Courtyard by Marriott Lake Buena Vista at Vista Centre

Rosen Shingle Creek

Rosen Shingle Creek
4.5 star property
Orlando
9.4 out of 10, Exceptional, (4346)
"Great resort "
United States
Camille
The price is NT$3,467
NT$3,901 total
includes taxes & fees
Dec 15 - Dec 16
Rosen Shingle Creek

Hilton Vacation Club Mystic Dunes Orlando

Hilton Vacation Club Mystic Dunes Orlando
4.0 star property
Kissimmee
9.0 out of 10, Wonderful, (4485)
"Great place"
United States
Derek
The price is NT$3,048
NT$4,521 total
includes taxes & fees
Dec 17 - Dec 18
Hilton Vacation Club Mystic Dunes Orlando

Marriott's Grande Vista

Marriott's Grande Vista
4.0 star property
Orlando
9.0 out of 10, Wonderful, (3671)
"Great stay "
United States
Monica
The price is NT$3,399
NT$3,824 total
includes taxes & fees
Dec 15 - Dec 16
Marriott's Grande Vista

DoubleTree by Hilton Orlando Airport

DoubleTree by Hilton Orlando Airport
4.0 star property
Airport North
8.8 out of 10, Excellent, (2168)
"airport shuttle was very convenient, room service was excellent too"
Canada
Kimberly
The price is NT$3,298
NT$3,711 total
includes taxes & fees
Dec 23 - Dec 24
DoubleTree by Hilton Orlando Airport

Margaritaville Resort Orlando

Margaritaville Resort Orlando
4.0 star property
Kissimmee
8.8 out of 10, Excellent, (3643)
"Great location, close to Disney, heated pool it was a big plus, Nice breakfast and service! "
United States
Eleni
The price is NT$3,746
NT$5,950 total
includes taxes & fees
Dec 15 - Dec 16
Margaritaville Resort Orlando

Rosen Plaza on International Drive

Rosen Plaza on International Drive
4.0 star property
International Drive District
9.2 out of 10, Wonderful, (1772)
"Great place to stay"
United States
Joshua
The price is NT$3,218
NT$3,709 total
includes taxes & fees
Dec 15 - Dec 16
Rosen Plaza on International Drive

Avanti International Resort

Avanti International Resort
4.0 star property
International Drive District
7.8 out of 10, Good, (4293)
"Enjoyed our stay "
United States
Sheltra
The price is NT$2,163
NT$3,064 total
includes taxes & fees
Dec 14 - Dec 15
Avanti International Resort

DoubleTree by Hilton Hotel Orlando Downtown

DoubleTree by Hilton Hotel Orlando Downtown
4.0 star property
Ivanhoe Village
8.2 out of 10, Very Good, (2824)
"clean hotel and breakfast "
United States
Petros
The price is NT$3,298
NT$3,711 total
includes taxes & fees
Dec 18 - Dec 19
DoubleTree by Hilton Hotel Orlando Downtown

Caribe Royale Orlando

Caribe Royale Orlando
4.5 star property
Orlando
9.2 out of 10, Wonderful, (4493)
"Clean and very friendly staff"
United States
Nafeeza
The price is NT$4,958
NT$6,911 total
includes taxes & fees
Dec 19 - Dec 20
Caribe Royale Orlando

Rosen Centre Hotel

Rosen Centre Hotel
4.0 star property
International Drive District
9.0 out of 10, Wonderful, (4128)
"The hotel was great!"
United States
Robin
The price is NT$3,345
NT$3,801 total
includes taxes & fees
Dec 23 - Dec 24
Rosen Centre Hotel

Universal’s Loews Portofino Bay Hotel

Universal’s Loews Portofino Bay Hotel
4.0 star property
Florida Center
9.0 out of 10, Wonderful, (1001)
"Excellent staff restaurants and rooms! "
United States
Catherine
The price is NT$18,998
NT$21,373 total
includes taxes & fees
Jan 11 - 2026/1/12
Universal’s Loews Portofino Bay Hotel
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Frequently asked questions

How much does it cost to stay in a 4-star hotel in Lake Nona Medical City?
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What's the difference between 5-star and 4-star hotels in Lake Nona Medical City?
Treat yourself to luxury living during your Lake Nona Medical City getaway by staying at a 4-star hotel. As well as featuring upscale surroundings, these properties are usually filled with amenities like large beds, bathrobes and plenty more. A 5-star hotel will go the extra mile to make your trip an even more indulgent and memorable one. Round-the-clock concierge assistance, luxurious spas and gourmet dining are just the start of the superior services and conveniences you'll likely have access to.
Does Lake Nona Medical City have any 4-star all-inclusive resorts?
Enjoy a carefree vacation experience where almost everything is included in the one upfront rate by using our "All inclusive" filter. Staying within budget is a breeze when your room, meals and many activities are already taken care of. After more options? Browse the great offers on our standard 4-star options in and around Lake Nona Medical City too.

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