Find Family Hotels in Lake Nona Medical City, FL

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Check availability on Lake Nona Medical City Family Hotels

Our top choices for Lake Nona Medical City family-friendly hotels

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La Quinta Inn & Suites by Wyndham Orlando Airport North

La Quinta Inn & Suites by Wyndham Orlando Airport North

La Quinta Inn & Suites by Wyndham Orlando Airport North
3.0 star property
Airport North
7.4 out of 10, Good, (829)
"Near the beach , very nice people at the reception. "
United States
Leonie
The price is NT$2,471
NT$2,780 total
includes taxes & fees
Dec 17 - Dec 18
La Quinta Inn & Suites by Wyndham Orlando Airport North
Outdoor banquet area
Rosen Shingle Creek

Rosen Shingle Creek

Rosen Shingle Creek
4.5 star property
Orlando
9.4 out of 10, Exceptional, (4345)
"Great resort "
United States
Camille
The price is NT$3,467
NT$3,901 total
includes taxes & fees
Dec 15 - Dec 16
Rosen Shingle Creek
Outdoor pool, pool umbrellas, sun loungers
Cambria Hotel Orlando Airport

Cambria Hotel Orlando Airport

Cambria Hotel Orlando Airport
3.0 star property
Orlando
8.8 out of 10, Excellent, (1944)
"Great place to stay "
United States
Yanersi
The price is NT$2,889
NT$3,250 total
includes taxes & fees
Dec 22 - Dec 23
Cambria Hotel Orlando Airport
Terrace/patio
Hyatt House Orlando Airport

Hyatt House Orlando Airport

Hyatt House Orlando Airport
3.5 star property
Airport North
9.6 out of 10, Exceptional, (2781)
"Great stay close to airport and plenty of dining available "
United States
Lonnie
The price is NT$3,761
NT$4,231 total
includes taxes & fees
Dec 15 - Dec 16
Hyatt House Orlando Airport
Lobby lounge
Aloft Orlando Lake Buena Vista

Aloft Orlando Lake Buena Vista

Aloft Orlando Lake Buena Vista
3.0 star property
Orlando
8.8 out of 10, Excellent, (1906)
"Great rooms, staff, and property!"
United States
Cindy
The price is NT$2,307
NT$2,596 total
includes taxes & fees
Dec 15 - Dec 16
Aloft Orlando Lake Buena Vista
Outdoor pool, pool umbrellas, sun loungers
Wyndham I-Drive Avanti Resort & Conference Center

Wyndham I-Drive Avanti Resort & Conference Center

Wyndham I-Drive Avanti Resort & Conference Center
3.5 star property
International Drive District
7.4 out of 10, Good, (3883)
"Room was good hotel was nice and clean"
United States
Amy
The price is NT$1,921
NT$2,793 total
includes taxes & fees
Dec 13 - Dec 14
Wyndham I-Drive Avanti Resort & Conference Center
Restaurant
Wingate by Wyndham - Orlando International Airport

Wingate by Wyndham - Orlando International Airport

Wingate by Wyndham - Orlando International Airport
3.0 star property
Airport North
8.8 out of 10, Excellent, (3736)
"Good room, good breakfast and convenient to the airport."
United States
Mark
The price is NT$2,498
NT$2,810 total
includes taxes & fees
Dec 15 - Dec 16
Wingate by Wyndham - Orlando International Airport
Waterslide
Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
4.0 star property
Orlando
9.4 out of 10, Exceptional, (4074)
"Beautiful resort"
United States
Antonese
The price is NT$3,467
NT$3,901 total
includes taxes & fees
Jan 5 - 2026/1/6
Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
Children's activities
DoubleTree by Hilton at the Entrance to Universal Orlando

DoubleTree by Hilton at the Entrance to Universal Orlando

DoubleTree by Hilton at the Entrance to Universal Orlando
4.0 star property
Florida Center
8.4 out of 10, Very Good, (6892)
"Wonderful stay. Great location!"
United States
Charmaine
The price is NT$3,059
NT$3,442 total
includes taxes & fees
Dec 15 - Dec 16
DoubleTree by Hilton at the Entrance to Universal Orlando
3 outdoor pools, open 7 AM to 10:00 PM, cabanas (surcharge)
Hyatt Regency Grand Cypress

Hyatt Regency Grand Cypress

Hyatt Regency Grand Cypress
4.0 star property
Orlando
9.2 out of 10, Wonderful, (2281)
"The staff was attentive and we really enjoyed the amenities! "
United States
Michelle
The price is NT$5,023
NT$7,405 total
includes taxes & fees
Dec 13 - Dec 14
Hyatt Regency Grand Cypress
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Lake Nona Medical City Hotel Reviews

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

10/10 Excellent
"Beautiful resort"
Antonese 3-night trip
Posted 1 day ago
Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

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Frequently asked questions

What's Lake Nona Medical City like for family-friendly vacations?
The relaxing destination of Lake Nona Medical City is a good choice if you've been thinking about a trip with your kids. The entertainment, lake views, and coffee shops are just some of the things that make this an attractive family vacation spot. Take to the air and fly into Orlando Intl. Airport (MCO), which is the closest airport, or Kissimmee, FL (ISM-Kissimmee Gateway), which is located 11.1 mi (17.8 km) from the center of Lake Nona Medical City.
What's there to see and do with your family in Lake Nona Medical City?
While you and your family are visiting Lake Nona Medical City, you might want to check out some kid-friendly attractions such as Universal Orlando Resort and Universal Studios Florida. Make sure you have plenty of time to take in activities in the area like Disney Springs™, Epcot®, and Walt Disney World® Resort.