Find hotels in Lake Nona Medical City, Orlando from NT$2,601

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Discover 27,610 Lake Nona Medical City hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Aloft Orlando Lake Nona

3.0 star property
Lake Nona Medical City
9.8 out of 10, Exceptional, (257)
"Beautiful hotel and excellent location. "
United States
Samue
The price is NT$3,561
NT$4,006 total
includes taxes & fees
Dec 22 - Dec 23
Aloft Orlando Lake Nona

Courtyard Orlando Lake Nona

3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (590)
"Great stay"
United States
Romulo
The price is NT$4,498
NT$5,111 total
includes taxes & fees
Dec 21 - Dec 22
Courtyard Orlando Lake Nona

Residence Inn Orlando Lake Nona

3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (324)
"Good hotel "
China
lily
The price is NT$5,311
NT$6,034 total
includes taxes & fees
Dec 18 - Dec 19
Residence Inn Orlando Lake Nona

La Quinta Inn & Suites by Wyndham Orlando Airport North

3.0 star property
Airport North, 10.9 km from Lake Nona Medical City
7.4 out of 10, Good, (797)
"Near the beach , very nice people at the reception. "
United States
Leonie
The price is NT$2,474
NT$2,783 total
includes taxes & fees
Dec 9 - Dec 10
La Quinta Inn & Suites by Wyndham Orlando Airport North

Wyndham Garden Orlando Airport

3.0 star property
Belle Isle, 11.9 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (3990)
"Excellent beds, clean and close to airport "
Canada
Rosalyn
The price is NT$2,649
NT$2,980 total
includes taxes & fees
Dec 15 - Dec 16
Wyndham Garden Orlando Airport

Seasons Florida Resort

2.0 star property
19.8 km from Lake Nona Medical City
8.8 out of 10, Excellent, (3281)
"Great room and service. "
United States
Derrick
The price is NT$1,898
NT$2,154 total
includes taxes & fees
Dec 8 - Dec 9
Seasons Florida Resort

Hampton Inn & Suites Orlando Airport @ Gateway Village

3.0 star property
Airport North, 10.6 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (2439)
"Great location to airport and food choices. "
United States
Aliza
The price is NT$3,099
NT$3,486 total
includes taxes & fees
Dec 22 - Dec 23
Hampton Inn & Suites Orlando Airport @ Gateway Village

Ramada by Wyndham Suites Orlando Airport

3.0 star property
Airport North, 10.4 km from Lake Nona Medical City
8.2 out of 10, Very Good, (5164)
"Great place to stay close to airport "
United States
Rebekah
The price is NT$2,788
NT$3,137 total
includes taxes & fees
Jan 5 - 2026/1/6
Ramada by Wyndham Suites Orlando Airport

DoubleTree by Hilton at the Entrance to Universal Orlando

4.0 star property
Florida Center, 21.7 km from Lake Nona Medical City
8.4 out of 10, Very Good, (6876)
"Wonderful stay. Great location!"
United States
Charmaine
The price is NT$2,792
NT$3,141 total
includes taxes & fees
Dec 15 - Dec 16
DoubleTree by Hilton at the Entrance to Universal Orlando

Magic Moment Resort & Kids Club, Dazzler Select by Wyndham

3.0 star property
21.6 km from Lake Nona Medical City
8.4 out of 10, Very Good, (2687)
"Very nice , clean and friendly place to stay with friends and family "
United States
Ariana
The price is NT$1,315
NT$2,556 total
includes taxes & fees
Dec 9 - Dec 10
Magic Moment Resort & Kids Club, Dazzler Select by Wyndham

Universal's Cabana Bay Beach Resort

3.5 star property
Florida Center, 22.2 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (5682)
"Great stay!"
Canada
Catherine
The price is NT$4,155
NT$4,674 total
includes taxes & fees
Dec 9 - Dec 10
Universal's Cabana Bay Beach Resort

Spark by Hilton Orlando near Universal

2.5 star property
Florida Center, 22.1 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (403)
"Wonderful staff great location to universal parks. "
United States
Desire
The price is NT$2,474
NT$2,783 total
includes taxes & fees
Dec 15 - Dec 16
Spark by Hilton Orlando near Universal

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

4.0 star property
22.5 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (4044)
"Very clean best resort "
United States
Shatira
The price is NT$3,474
NT$3,908 total
includes taxes & fees
Jan 5 - 2026/1/6
Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

Palazzo Lakeside Hotel

3.0 star property
20.5 km from Lake Nona Medical City
8.2 out of 10, Very Good, (5146)
"Overall good experience would stay again"
United States
Jacquelyn
The price is NT$1,036
NT$2,239 total
includes taxes & fees
Dec 14 - Dec 15
Palazzo Lakeside Hotel

Wingate by Wyndham - Orlando International Airport

3.0 star property
Airport North, 11 km from Lake Nona Medical City
8.8 out of 10, Excellent, (3720)
"Good room, good breakfast and convenient to the airport."
United States
Mark
The price is NT$2,558
NT$2,878 total
includes taxes & fees
Dec 9 - Dec 10
Wingate by Wyndham - Orlando International Airport

Hyatt House Orlando Airport

3.5 star property
Airport North, 10.6 km from Lake Nona Medical City
9.6 out of 10, Exceptional, (2766)
"Great stay close to airport and plenty of dining available "
United States
Lonnie
The price is NT$3,767
NT$4,238 total
includes taxes & fees
Dec 15 - Dec 16
Hyatt House Orlando Airport

Rosen Shingle Creek

4.5 star property
16.9 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (4324)
"Great resort "
United States
Camille
The price is NT$3,474
NT$3,908 total
includes taxes & fees
Dec 14 - Dec 15
Rosen Shingle Creek

Tru By Hilton Orlando Convention Center Area, FL

3.5 star property
International Drive District, 19.8 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (3646)
"Great location clean rooms "
United States
Erika
The price is NT$2,474
NT$2,783 total
includes taxes & fees
Dec 14 - Dec 15
Tru By Hilton Orlando Convention Center Area, FL

Wyndham Lake Buena Vista – Disney Springs® Area

4.0 star property
23.2 km from Lake Nona Medical City
8.8 out of 10, Excellent, (2772)
"Great location and consistent service, we’ve stayed many times. "
United States
Tracy
The price is NT$3,239
NT$4,910 total
includes taxes & fees
Dec 15 - Dec 16
Wyndham Lake Buena Vista – Disney Springs® Area

SpringHill Suites by Marriott Orlando Theme Parks/Lake Buena Vista

3.0 star property
21.8 km from Lake Nona Medical City
8.6 out of 10, Excellent, (3444)
"I this hotel is the best place to stay "
United States
Manese
The price is NT$2,718
NT$3,058 total
includes taxes & fees
Jan 4 - 2026/1/5
SpringHill Suites by Marriott Orlando Theme Parks/Lake Buena Vista
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona Medical City
Learn more about Lake Nona Medical City

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Bay Lake

Home to all four Walt Disney World Resort theme parks and one water park, this city offers endless entertainment, including Disney's Fort Wilderness Resort & Campground and Magnolia and Palm Golf Courses.

Downtown Orlando

Orlando's historic core boasts art galleries, retail, restaurants, and nightclubs, with attractions like Lake Eola Park, Linton E. Allen Memorial Fountain, and performing arts theaters, all accessible via public transportation.

Florida Center

While visiting Florida Center, you might make a stop by sights like Universal Orlando Resort and Universal Studios Florida.

Champions Gate

Abundant dining options and pristine golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

Top Lake Nona Medical City Hotel Reviews

Find out more about Lake Nona Medical City

Top reasons to visit Lake Nona Medical City

  • Family-Friendly Activities: Lake Nona Medical City offers numerous parks and a water park, making it perfect for families.
  • Outdoor Adventure: Enjoy a variety of outdoor activities in scenic lakes and urban parks.
  • Shopping and Dining: Explore a shopping mall and vibrant dining options in nearby downtown Orlando.
  • Resort and Golf Options: Relax at local resorts or hit the golf courses for a leisure day.
  • Unique Accommodations: Choose from family-friendly, pet-friendly, or romantic lodging to suit your needs.

Find great hotels near Lake Nona Medical City

Discover a variety of hotel accommodations in Lake Nona Medical City, Orlando, designed to cater to every traveler. Whether you're seeking a family-friendly resort, a pet-friendly stay, or a romantic getaway, this vibrant area offers top hotels and new options to enhance your experience. Enjoy easy access to local attractions while relaxing in comfort and style at your chosen lodging.

  • Westgate Lakes Resort & Spa Universal Studios Area: Embrace a vibrant and inclusive atmosphere at the Westgate Lakes Resort & Spa, a premier destination for LGBTQIA travelers and pet lovers alike. Located 20.9km from Lake Nona Medical City, this 4-star resort offers a unique blend of luxury and comfort. Guests can enjoy well-appointed accommodations along with pet-friendly amenities, making it a great choice for those traveling with furry companions. The property features a range of business-friendly services, ensuring that both leisure and work travelers feel at home. With its inviting ambiance, Westgate Lakes allows guests to unwind while enjoying the great Florida sunshine.
  • Sheraton Vistana Villages Resort Villas, I-Drive/Orlando: Perfectly situated 19.3km from Lake Nona Medical City, the Sheraton Vistana Villages Resort Villas is a family-friendly oasis that proudly boasts eco-certification. This 4-star resort offers spacious villas designed for relaxation and quality family time. Kids will love the dedicated amenities, including a playground and children's pool, while parents can appreciate the environmentally conscious practices in place. With its beautiful landscaping and engaging activities, this resort creates an ideal setting for families seeking a memorable vacation experience in Orlando.
  • DoubleTree by Hilton Hotel Orlando at SeaWorld: Experience romantic getaways and unforgettable business trips at the DoubleTree by Hilton Hotel Orlando at SeaWorld, located 19.3km from Lake Nona Medical City. This 4-star resort is known for its charming romance packages, making it a popular choice for couples. Relax by the outdoor pool, savor delicious meals with pool views, and indulge in spa services for a rejuvenating experience. The pet-friendly policy ensures that no family member is left behind, and the attentive staff is committed to making your stay enjoyable and memorable.

Where to stay near Lake Nona Medical City

Experience the perfect blend of relaxation and adventure in Lake Nona Medical City and its surrounding areas. Enjoy family-friendly activities at Lake Nona’s parks or explore the vibrant downtown Orlando, rich with dining and entertainment options. For those seeking romance, the scenic views and charming atmosphere of Southeast Orlando provide an ideal backdrop. Discover the friendly vibes and diverse attractions that make this region a perfect vacation spot for all types of travelers.

  • Orlando: As a bustling metropolis, Orlando is renowned for its vibrant entertainment scene and family-friendly attractions. Situated in central Florida, the city is famous for its theme parks, including Walt Disney World and Universal Studios, making it a top destination for visitors year-round. The city offers a variety of shopping areas, arts centers, and lively resorts. Beyond the parks, you can explore local landmarks such as the Orlando Museum of Art and Lake Eola Park. With a diverse array of restaurants and nightlife options, Orlando guarantees a fun-filled experience for all types of travelers.
  • Kissimmee: Located approximately 16.1km from Lake Nona Medical City, Kissimmee is a charming city known for its family-oriented atmosphere and proximity to major theme parks. This city features a wide range of resorts and shopping malls, catering to both leisure and business travelers. Kissimmee serves as a great base for exploring nearby attractions, including the Kissimmee Lakefront Park and Old Town, which offers shopping, dining, and entertainment. The city’s welcoming vibe and convenient location make it an ideal spot for those seeking adventure and relaxation alike.
  • Lake Nona: just 1.6km from Lake Nona Medical City, this innovative neighborhood is rapidly becoming a hub for health, wellness, and technology. Lake Nona is home to modern residential communities, shopping centers, and recreational facilities, including sports stadiums. The area is designed to promote an active lifestyle, with plenty of parks, walking trails, and lakes to explore. Additionally, Lake Nona hosts various events throughout the year, making it a lively place for visitors to enjoy entertainment and community spirit. Its blend of contemporary living and vibrant culture makes Lake Nona a must-visit.

Things to do near Lake Nona Medical City

Lake Nona Medical City offers a family-friendly vacation with plenty of entertainment options. Visitors can enjoy nearby resorts and golf courses, as well as a shopping mall center for all your retail needs. Don't miss the entertainment choices available, including a movie theater for film enthusiasts and a water park for those seeking some fun in the sun.

Shopping

For shopping near Lake Nona Medical City, visit the Florida Mall, just 14.5km away, offering a vibrant mix of entertainment and shopping. Additionally, check out the 192 Flea Market, located 19.3km away, for unique finds and local goods. The Oak Ridge Gun Range is also nearby for specialty items.

Recreation

Austin-Tindall Regional Park offers an energetic atmosphere perfect for sports enthusiasts, while Eagle Creek Golf Club invites you to enjoy a round of golf amid beautiful outdoor settings. For a more tranquil experience, Moss Park provides a peaceful environment ideal for relaxation and leisurely walks.

Adventure

Aquatica is a thrilling waterpark located 19.3km from Lake Nona Medical City, offering exciting slides and family-friendly attractions for a splashing good time. For karting enthusiasts, the Orlando Kart Center, situated 11.3km away, provides an adrenaline-pumping racing experience. iFly Orlando, 20.9km away, lets you experience the thrill of indoor skydiving.

Nightlife

Experience a captivating evening at Medieval Times, where romance and entertainment blend in a thrilling theater performance just 19.3km away. For family fun, visit Skate Reflections, an arcade adventure zone, or enjoy the excitement of rides at Cross Country Creek, both located 17.7km from Lake Nona Medical City.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Lake Nona Medical City

For a budget-friendly trip to Lake Nona Medical City, consider visiting during the cheaper months of August to September and November. Booking your hotel about a month in advance or checking last-minute deals on platforms like Expedia can help you save money. Tuesdays typically offer the lowest rates, while Saturdays are the priciest. Utilize Expedia’s filters for eco-friendly accommodations and package deals that combine flights and activities. Don't forget to look for refundable booking options and special offers to maximize your savings.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Lake Nona Medical City are August to September and November, where the prices are slightly lower. This is in comparison to March to April and December, where prices are slightly higher.
  • The best time to book a hotel: Booking a hotel around Lake Nona Medical City about 1 month out from when you are planning to stay is usually when prices are lowest. If you're a little more spontaneous, you could also peruse Expedia's last minute deals for hotels, look out for the green banner below the price, as this indicates a cheaper deal.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Lake Nona Medical City is Tuesday. The most expensive day to stay around Lake Nona Medical City is Saturday.
  • Find cheap hotels on Expedia: Expedia's search tool enables you to choose your budget, desired location, and additional preferences. You can arrange your results to display prices from lowest to highest, making it easy to find the most affordable hotels first. Additionally, you have the option to narrow down your choices by hotel type. For instance, selecting the Eco-certified hotels filter will showcase sustainable and environmentally friendly accommodations that you can book.
  • Consider bundling your trip: You can cut costs by combining your hotel stay at Lake Nona Medical City with your flights and activities through an Expedia package deal.

Find the best attractions near Lake Nona Medical City

Lake Nona Medical City offers a fantastic vacation destination for families and outdoor enthusiasts. Visitors can enjoy a variety of popular attractions, including theme parks, urban parks, and scenic lakes. This area provides numerous opportunities for outdoor activities and family-friendly experiences, making it an ideal spot for those looking to explore both natural beauty and city life.

  • Orange County Convention Center: This vibrant arts center, located 19.3km from Lake Nona Medical City, is known for its cultural vibes. It hosts various events, including exhibitions, conventions, and performances, making it a hub for creativity and community engagement.
  • University of Central Florida College of Medicine: Just 483m away, this modern college showcases cutting-edge medical education and research. Its city vibes create an inspiring atmosphere, ideal for those interested in healthcare innovations and academic pursuits.
  • Osceola Heritage Park: Situated 12.9km from Lake Nona, this urban park offers a blend of outdoor activities and family-friendly events. With its lush green spaces and city vibes, it's perfect for picnics, concerts, and enjoying time with loved ones.

Best time to go to Lake Nona Medical City

The best time to visit Lake Nona Medical City is dependent on what kind of holiday you are seeking. August is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with moderate rain. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January60.6°F (15.9°C)Light RainMostly SunnyAverageAverage
February64.4°F (18.0°C)Light RainMostly SunnyAverageAverage
March67.6°F (19.8°C)Light RainMostly SunnySlightly HighSlightly High
April72.7°F (22.6°C)Light RainMostly SunnyAverageSlightly High
May77.2°F (25.1°C)Light RainMostly SunnySlightly LowAverage
June81.1°F (27.3°C)Light RainMostly SunnyAverageAverage
July82.4°F (28.0°C)Moderate RainMostly SunnySlightly HighAverage
August82.6°F (28.1°C)Moderate RainMostly SunnyAverageSlightly Low
September80.4°F (26.9°C)Moderate RainMostly SunnySlightly LowSlightly Low
October75.2°F (24.0°C)Light RainMostly SunnySlightly LowAverage
November68.5°F (20.3°C)Light RainMostly SunnyAverageSlightly Low
December64.4°F (18.0°C)No RainMostly SunnySlightly HighSlightly High

The nearest major airports for your trip to Lake Nona Medical City

Lake Nona Medical City is conveniently accessible via several major airports. Orlando International Airport (MCO) is only 8.0km away, with nearby accommodations like The Ritz-Carlton Orlando, Grande Lakes and Rosen Shingle Creek, both about 12.9km from MCO. Transportation options from these hotels include shuttles available on request. Kissimmee Gateway Airport (ISM) is located 17.7km away, with luxury hotels such as Waldorf Astoria Orlando and Encore Resort and Water Park nearby. Daytona Beach International Airport (DAB) is farther at 512.9km, featuring hotels like Hilton Daytona Beach Oceanfront Resort, just 6.4km from the airport. Each location offers convenient access to Lake Nona Medical City.

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Frequently asked questions

What's it like in Lake Nona Medical City?
Lake Nona Medical City is a neighborhood that travelers like for its restaurants.
What's a favorite place to stay in Lake Nona Medical City?
Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favorite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona.
How many hotels are there in Lake Nona Medical City?
Expedia has 5 Lake Nona Medical City hotels and other accommodations, and one might make a good home base for venturing out into the greater Orlando area.
If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to review the best options available in Lake Nona Medical City.
Where can I learn more about changing or cancelling my trip to Lake Nona Medical City?
For more information about changing or cancelling your trip to Lake Nona Medical City, click here.
What is there to do around this Orlando neighborhood?
Eagle Creek Golf Club, USTA National Campus, and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Lake Hart and Kissimmee Bay Country Club are a couple of other sights to visit.