Find Resorts & Hotels with Spas in Clayton, MO

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Check availability on Clayton Resorts & Hotels with Spas

Tonight
Feb 5 - Feb 6
Tomorrow
Feb 6 - Feb 7
This weekend
Feb 6 - Feb 8
Next weekend
Feb 13 - Feb 15

Our top choices for Clayton hotels with a spa

Body treatments, aromatherapy, hot stone massages, deep-tissue massages

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (556 reviews)
"Great property. Concierge level wonderful. "
United States
Mike
The price is NT$15,731
NT$18,364 total
includes taxes & fees
Mar 8 - Mar 9
The Ritz-Carlton, St. Louis
Massages

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1,593 reviews)
"Clean room and the hotel itself is just gorgeous."
United States
anthony
The price is NT$4,228
NT$5,101 total
includes taxes & fees
Feb 12 - Feb 13
21C Museum Hotel St Louis
Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very Good, (1,000 reviews)
"The room was great. I enjoyed my stay. "
United States
Wanda
The price is NT$5,646
NT$7,122 total
includes taxes & fees
Mar 8 - Mar 9
Ameristar Casino Resort and Spa
Couples treatment rooms, hot tub, body treatments, aromatherapy

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,000 reviews)
"Great service, great staff , room service food really good,, great view of the arch and the river. "
United States
Jose
The price is NT$13,083
NT$15,298 total
includes taxes & fees
Feb 12 - Feb 13
Four Seasons Hotel St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Clayton

Pool
Breakfast included

Top Clayton Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
" Clean, spacious, amenities and location everything was on point. The FREE breakfast and complimentary evening snacks were all delicious! Friendly staff made us feel welcome"
Liliana 4-night trip
Posted 20 hours ago
Drury Plaza Hotel St. Louis at the Arch

Frequently asked questions

Looking for a spa hotel in Clayton?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in Clayton. Be sure to pay a visit to the museums during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your vacation.
What's there to see and do in Clayton?
Enjoy all that Clayton has to offer when you visit Chapel of St. Timothy And St. Titus, Concordia Seminary, St. Louis Union Station, and Busch Stadium. If you have some spare time during your trip, you might want to check out Gateway Arch and Saint Louis Galleria Mall.
What is a Clayton spa hotel?
Spa hotels in Clayton provide lodging and have an on-site spa offering services including therapies as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

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