The Best Hotels Closest to St. Louis Science Center in St. Louis for 2026

A space shuttle exhibit with a large model of a space shuttle, a red pillar, and informational displays.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for St. Louis Science Center hotels

1. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 1 km from St. Louis Science Center

NT$4,382

NT$5,167 total

includes taxes & fees

Sep 7 - Sep 8

Desk, iron/ironing board, cribs (free), rollaway beds (surcharge)

2. Drury Inn & Suites St. Louis Forest Park

2 km from St. Louis Science Center

Jennifer

NT$4,711

NT$5,508 total

includes taxes & fees

Sep 3 - Sep 4

3. The Royal Sonesta Chase Park Plaza St. Louis

Central West End, 1.8 km from St. Louis Science Center

Lyn

NT$5,249

NT$7,122 total

includes taxes & fees

Sep 7 - Sep 8

4. Element by Marriott St. Louis Midtown

Midtown, 2.7 km from St. Louis Science Center

Corderoa

NT$4,269

NT$4,991 total

includes taxes & fees

Sep 27 - Sep 28

5. AC Hotel St. Louis Central West End

Central West End, 1.8 km from St. Louis Science Center

chris

NT$4,522

NT$5,332 total

includes taxes & fees

Sep 3 - Sep 4

6. Hotel Indigo St Louis - Central West End by IHG

Central West End, 1.7 km from St. Louis Science Center

Simon

NT$4,237

NT$5,343 total

includes taxes & fees

Sep 27 - Sep 28

7. The West End

Central West End, 2.3 km from St. Louis Science Center

Isabella

NT$2,715

NT$3,807 total

includes taxes & fees

Aug 31 - Sep 1

8. Aloft by Marriott St Louis Central West End

Central West End, 1.8 km from St. Louis Science Center

Khristina

NT$3,601

NT$4,211 total

includes taxes & fees

Sep 1 - Sep 2

Premium bedding, desk, laptop workspace, cribs (free)

9. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 0.9 km from St. Louis Science Center

paullita jeanne

NT$4,945

NT$5,782 total

includes taxes & fees

Sep 6 - Sep 7

In-room safe, desk, blackout drapes, iron/ironing board

Suite, 1 King Bed | In-room safe, desk, blackout drapes, iron/ironing board

10. DoubleTree by Hilton St. Louis Forest Park

Central West End, 1.3 km from St. Louis Science Center

Kevin

NT$4,981

NT$5,874 total

includes taxes & fees

Sep 6 - Sep 7

11. White House at Grand Central

3 km from St. Louis Science Center

Triman

NT$2,549

NT$4,088 total

includes taxes & fees

Aug 31 - Sep 1

Suite, Private Bathroom (Diamonds and Pearls Luxury Suite) | Premium bedding, iron/ironing board (on request), WiFi (free)

Room, Private Bathroom (Reflections) | Premium bedding, iron/ironing board (on request), WiFi (free)

Suite, Private Bathroom | Premium bedding, iron/ironing board (on request), WiFi (free)

12. Central West End B&B

Central West End, 3 km from St. Louis Science Center

Stacee

NT$5,205

NT$6,549 total

includes taxes & fees

Aug 31 - Sep 1

Standard Double Room | Premium bedding, pillowtop beds, desk, laptop workspace

13. Forest Park Hotel by MDR

The Hill, 1.8 km from St. Louis Science Center

wahwah

NT$2,442

NT$3,002 total

includes taxes & fees

Sep 28 - Sep 29

Premium Room, 1 King Bed (Upgraded Bedding & Snack, Smoke Free) | In-room safe, desk, blackout drapes, iron/ironing board (on request)

14. Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

The Hill, 1.8 km from St. Louis Science Center

LaTonya

NT$2,673

NT$3,126 total

includes taxes & fees

Sep 2 - Sep 3

Room, 1 King Bed, Hearing Accessible (Roll in Shower) | In-room safe, desk, blackout drapes, iron/ironing board

15. Drury Plaza Hotel St. Louis Brentwood

6.5 km from St. Louis Science Center

Eric

NT$4,300

NT$5,105 total

includes taxes & fees

Sep 6 - Sep 7

Suite, Private Bathroom (Thomas Hart Benton Suite) | Desk, iron/ironing board (on request), WiFi (free)

Desk, iron/ironing board (on request), WiFi (free)

16. Benton Park Inn

5.5 km from St. Louis Science Center

NT$4,240

NT$4,958 total

includes taxes & fees

Sep 2 - Sep 3

17. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 7.1 km from St. Louis Science Center

misty

NT$4,837

NT$5,656 total

includes taxes & fees

Sep 3 - Sep 4

Daily cooked-to-order breakfast for a fee

18. Courtyard by Marriott St. Louis Brentwood

5.5 km from St. Louis Science Center

Aaron

NT$3,467

NT$4,240 total

includes taxes & fees

Sep 6 - Sep 7

19. Live by Loews - St.Louis

Downtown St. Louis, 6.7 km from St. Louis Science Center

Royce

NT$5,027

NT$5,979 total

includes taxes & fees

Aug 31 - Sep 1

20. The Lodge at Grant's Trail

10.1 km from St. Louis Science Center

NT$5,976

NT$6,872 total

includes taxes & fees

Aug 31 - Sep 1

View all properties

Compare popular hotels close to St. Louis Science Center

Property	Property class	Guest rating
Hampton Inn & Suites St. Louis at Forest Park	9.4 Exceptional 1,002 reviews	View
Drury Inn & Suites St. Louis Forest Park	9.4 Exceptional 1,007 reviews	View
The Royal Sonesta Chase Park Plaza St. Louis	9.2 Wonderful 1,005 reviews	View
Element by Marriott St. Louis Midtown	9.0 Wonderful 817 reviews	View
AC Hotel St. Louis Central West End	9.0 Wonderful 832 reviews	View

Top St. Louis Science Center Hotel Reviews

Drury Inn & Suites St. Louis Forest Park

10/10 Excellent

"Put it like this there wasn't one thing that I didn't like or wasn't satisfied with"

Clayton Plaza Hotel & Extended Stay

10/10 Excellent

"Clean room, great staff, great location!"

Aloft by Marriott St Louis Central West End

8/10 Good

"Contemporary rooms and many entertainment."

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

8/10 Good

"Neat niche property in the heart of downtown StL. Definitely not a luxury stay, but fun. Easy to get to"

The Cheshire

10/10 Excellent

"Really cool place to stay recommend it!!"

AC Hotel St. Louis Central West End

10/10 Excellent

"Very nice and clean. Lots of nice restaurants in the area too."

Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

8/10 Good

"Clean and friendly but need to upgrade their TV"

Other attractions near St. Louis Science Center

A modern building with large glass windows and a garden with red and pink tulips.

Jewel Box

Made of stacked glass in a restored art deco style, this glass house from the 1930s continues to flourish with tropical trees, hanging plants and a large fountain.

See properties

A modern building with large glass windows, surrounded by a garden with red and pink tulips and purple flowers.

Forest Park

9.2/10 (3,389 reviews)

Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.

See properties

A gazebo with columns and a dome roof, surrounded by a pond and greenery.

Pagoda Circle

As one of the cornerstones of Forest Park for about a century, this grassy island and its bandstand offer an excellent concert spot.

See properties

A well-lit building with multiple flags, including the American flag, and a parking area with cars.

The Muny Theater

8.6/10 (7 reviews)

You can enjoy a show at The Muny Theater during your trip to St. Louis. Amble around the area's lush forest or attend a sporting event.

See properties

Highlands Golf & Tennis Center

Catch an event at Highlands Golf & Tennis Center during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

See properties

Atomic Cowboy

Atomic Cowboy is just one of the places to see in St. Louis, so why not enjoy the other things to explore during your travels?

See properties

Atomic by Jamo

Atomic by Jamo is just one of the places to see in St. Louis, so why not enjoy the other things to explore during your travels?

See properties

Frequently asked questions

What's the area like around St. Louis Science Center?

St. Louis Science Center is located in a welcoming area of St. Louis known for its picturesque gardens and sporting events. If you're looking for a convenient place to stay, check out the 68 hotels and other accommodations you'll find within a mile.

Where is the best place to stay near St. Louis Science Center?

Hampton Inn & Suites St. Louis at Forest Park is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.6 mi (1 km) from St. Louis Science Center. Other good options within a short distance include DoubleTree by Hilton St. Louis Forest Park and Home2 Suites by Hilton St. Louis/Forest Park.

How many hotels will I be able to find near St. Louis Science Center?

Expedia has 68 hotels and other accommodations within a mile from St. Louis Science Center.

If I need to cancel the hotel reservation for my stay near St. Louis Science Center, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best options available near St. Louis Science Center.

Where can I learn more about changing or cancelling my trip in the area near St. Louis Science Center?

To access more information about changing or cancelling your stay near St. Louis Science Center, go to https://www.expedia.com/service/.

What can I see and do near St. Louis Science Center?

Cathedral Basilica of St. Louis, St. Louis Art Museum, and Scott Joplin House State Historic Site feature captivating exhibits. St. Louis Union Station, Jewel Box, and Washington Avenue Historic District are monuments to see when you're exploring the area around St. Louis Science Center. You can check out the local talent at The Muny Theater, Fox Theater, and Powell Hall.

Find hotels near St. Louis Science Center, St. Louis from NT$3,002

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for St. Louis Science Center hotels

1. Hampton Inn & Suites St. Louis at Forest Park

2. Drury Inn & Suites St. Louis Forest Park

3. The Royal Sonesta Chase Park Plaza St. Louis

4. Element by Marriott St. Louis Midtown

5. AC Hotel St. Louis Central West End

6. Hotel Indigo St Louis - Central West End by IHG

7. The West End

8. Aloft by Marriott St Louis Central West End

9. Home2 Suites by Hilton St. Louis/Forest Park

10. DoubleTree by Hilton St. Louis Forest Park

11. White House at Grand Central

12. Central West End B&B

13. Forest Park Hotel by MDR

14. Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

15. Drury Plaza Hotel St. Louis Brentwood

16. Benton Park Inn

17. Drury Plaza Hotel St. Louis at the Arch

18. Courtyard by Marriott St. Louis Brentwood

19. Live by Loews - St.Louis

20. The Lodge at Grant's Trail

Compare popular hotels close to St. Louis Science Center

Top St. Louis Science Center Hotel Reviews

Drury Inn & Suites St. Louis Forest Park

Clayton Plaza Hotel & Extended Stay

Aloft by Marriott St Louis Central West End

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

The Cheshire

AC Hotel St. Louis Central West End

Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

Other attractions near St. Louis Science Center

Jewel Box

Forest Park

Pagoda Circle

The Muny Theater

Highlands Golf & Tennis Center

Atomic Cowboy

Atomic by Jamo

Frequently asked questions

Explore a world of travel with Expedia