Find Resorts & Hotels with Spas in St. Louis, MO

Top St. Louis (and vicinity) attractions for a relaxing vacation

For travelers seeking a rejuvenating escape in the greater St. Louis area, this vibrant region offers a blend of cultural and relaxing experiences. Start your journey in Forest Park, where you can enjoy scenic trails and beautiful gardens—perfect for a leisurely stroll before or after spa treatments. Don't miss the Missouri Botanical Garden, a stunning oasis where you can immerse yourself in nature's tranquility and perhaps find inspiration for your wellness journey. For art enthusiasts, the Saint Louis Art Museum provides not just a visual feast but also a serene environment to unwind, and the nearby Grand Center Arts District is filled with charming cafes and galleries. If you’re up for a bit of adventure, the Gateway Arch offers breathtaking views of the city and the Mississippi River, which can be a refreshing way to get your blood pumping before indulging in a luxurious spa day. The Clayton area, known for its upscale hotels with spa services, is particularly appealing, offering a sophisticated atmosphere along with fine dining and boutique shopping, ensuring that your every need is catered to. Here, you can unwind in beautifully appointed accommodations and enjoy attentive service, making your stay not just comfortable, but truly pampered.

Find the best hotels & resorts with spas in St. Louis (and vicinity)

For travelers seeking a rejuvenating escape in St. Louis, these top hotels offer exceptional spa amenities and serene atmospheres designed for relaxation and wellness.

Four Seasons Hotel St Louis

• Why it's great for tailored spa getaway: The Four Seasons Hotel St Louis is a premier destination for spa enthusiasts, an impressive review rating of 9.4. Guests can indulge in a full-service spa experience that includes body treatments, aromatherapy, and luxurious couples treatment rooms, ensuring a truly pampering stay. The spa also features a sauna, steam room, and hot tub, making it an ideal retreat for relaxation and rejuvenation.
• Other amenities: In addition to its spa offerings, this luxurious hotel provides a stunning river view, an outdoor pool, and a well-equipped 24-hour fitness center. Guests can enjoy valet parking, room service around the clock, and a rooftop terrace for breathtaking views. The hotel’s concierge is available to assist with reservations and local recommendations, enhancing the overall experience for every traveler.
• Neighborhood: Downtown St. Louis
• Nearby attractions: Mississippi River - 0.35 miles, Dome at America’s Center - 0.49 miles, Horseshoe St. Louis Casino - 0.08 miles

The Royal Sonesta Chase Park Plaza St. Louis

• Why it's great for tailored spa getaway: The Royal Sonesta Chase Park Plaza St. Louis is an elegant choice for travelers seeking a spa getaway, with a solid review rating of 9.0. While the spa features treatment rooms for a variety of services, guests can also enjoy the hotel’s luxurious feel, complete with designer toiletries and premium bedding for a restful night’s sleep.
• Other amenities: This upscale hotel also offers a health club, valet parking, and a poolside bar for relaxation and refreshment. Guests can take advantage of the concierge services for personalized recommendations and assistance. The hotel’s central location in the Central West End provides easy access to local attractions, ensuring that guests have a delightful stay filled with both relaxation and exploration.
• Neighborhood: Central West End
• Nearby attractions: Forest Park - 0.0 miles

21C Museum Hotel St Louis

• Why it's great for tailored spa getaway: The 21C Museum Hotel St Louis is a chic option for travelers looking for a unique spa experience, with a strong review rating of 9.0. The hotel's onsite spa features a steam room and massage services, allowing guests to unwind in a stylish setting that combines art and relaxation. With its contemporary décor and artistic flair, this hotel offers a refreshing escape from the everyday hustle.
• Other amenities: Guests can enjoy an indoor pool, accessible fitness facilities, and room amenities like deep soaking bathtubs and complimentary toiletries. The hotel also provides valet parking and daily housekeeping for added convenience. Its central location allows easy access to local attractions, making it a perfect blend of relaxation and exploration for travelers.
• Neighborhood: Downtown West
• Nearby attractions: St. Louis Union Station - 0.42 miles, Enterprise Center - 0.4 miles, City Museum - 0.33 miles

DoubleTree by Hilton Hotel St. Louis - Chesterfield

• Why it's great for tailored spa getaway: The DoubleTree by Hilton Hotel St. Louis - Chesterfield is a welcoming retreat for spa lovers, featuring treatment rooms for ultimate relaxation, and an excellent review rating of 8.6. This hotel provides a comfortable environment where guests can unwind after a busy day, making it an ideal choice for those looking to recharge.
• Other amenities: Guests can enjoy an indoor pool with hot tub access, a health club, and various fitness facilities to maintain their wellness routine. Additional offerings include onsite shopping, a poolside bar, and complimentary daily housekeeping. The hotel’s location allows for easy exploration of Chesterfield's attractions, enhancing the overall experience for travelers.
• Nearby attractions: Chesterfield Arts - 1.05 miles, The J - Chesterfield Gym & Fitness Center - 1.46 miles

Ameristar Casino Resort and Spa

• Why it's great for tailored spa getaway: The Ameristar Casino Resort and Spa is perfect for travelers seeking a full-service spa experience, rated 8.4 by guests. This resort features an array of spa treatments including aromatherapy, body treatments, and massages, ensuring relaxation in a vibrant setting that combines entertainment and wellness.
• Other amenities: In addition to the spa, guests can enjoy a variety of amenities including a pool, hot tub, and 24-hour fitness facilities. The resort also offers onsite dining options, a concierge service, and easy access to nearby golf courses. With premium bedding in each room, travelers can expect a comfortable and luxurious stay.
• Nearby attractions: Ameristar Casino St. Charles - 0.01 miles, Historic Main Street - 0.68 miles, Lewis & Clark Boathouse and Nature Center - 0.71 miles