Find Boutique Hotels in Downtown St. Louis, MO

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Check availability on Downtown St. Louis Boutique Hotels

Our top choices for Downtown St. Louis boutique hotels

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1914)
"Clean rooms, good coffee and fresh muffins and friendly service."
United States
Colleen
The price is NT$3,717
NT$4,420 total
includes taxes & fees
Dec 25 - Dec 26
Moonrise Hotel

The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.6 out of 10, Excellent, (1000)
"Excellent place to stay. "
United States
Todd
The price is NT$3,685
NT$4,375 total
includes taxes & fees
Jan 18 - 2026/1/19
The Cheshire

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
Clayton
8.4 out of 10, Very Good, (577)
"Love this place."
United States
Robert
The price is NT$3,847
NT$4,790 total
includes taxes & fees
Dec 28 - Dec 29
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Downtown St. Louis Hotel Reviews

Frequently asked questions

What's there to see and do in Downtown St. Louis?
Visitors speak positively about this destination's acclaimed theaters, great live music, and top museums. Activities and attractions to experience around Downtown St. Louis include Gateway Arch, Museum at the Gateway Arch, and Cardinals Hall of Fame and Museum. You might also want to see spots like St. Louis Union Station, Gateway Arch National Park, and Kiener Plaza during your trip.
What's the best way to get to my boutique hotel in Downtown St. Louis?
You have a few options for getting to and around Downtown St. Louis. The nearest major airport is St. Louis Lambert Intl. Airport (STL), which is located 12.5 mi (20.1 km) away. Nearby metro stations include 8th and Pine Station, Stadium Station, and Convention Center Station.

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