Find Luxury Hotels in Downtown St. Louis, MO

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Downtown St. Louis Luxury Hotels

Our top choices for Downtown St. Louis luxury hotels

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1002)
"Everything exceeded my expectations from the welcoming staff to the luxuriously appointed room, to the 4 feet deep bathtub in which to soak my cares away--it was a total dream come true. I would come back in a heartbeat at this home away from home. "
United States
Lynne
The price is NT$13,017
NT$15,221 total
includes taxes & fees
Jan 14 - 2026/1/15
Four Seasons Hotel St Louis

The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1008)
"Great location "
United States
Gregory
The price is NT$3,989
NT$4,664 total
includes taxes & fees
Dec 28 - Dec 29
The Westin St. Louis

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (3288)
"Our stay was very enjoyable. Location was great and kids loved the indoor pool!"
United States
Christy
The price is NT$4,234
NT$4,951 total
includes taxes & fees
Dec 22 - Dec 23
Drury Plaza Hotel St. Louis at the Arch

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1156)
"Really nice hotel!"
United States
DARIN
The price is NT$2,738
NT$3,257 total
includes taxes & fees
Dec 22 - Dec 23
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.4 out of 10, Very Good, (1008)
"Nice historic hotel"
United States
Michelle
The price is NT$4,861
NT$5,781 total
includes taxes & fees
Dec 25 - Dec 26
St. Louis Union Station Hotel, Curio Collection by Hilton

Missouri Athletic Club

Missouri Athletic Club
3.5 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1000)
"The room was nice and the staff was excellent."
United States
Annette
The price is NT$5,301
NT$6,198 total
includes taxes & fees
Dec 28 - Dec 29
Missouri Athletic Club

Le Meridien St. Louis Downtown

Le Meridien St. Louis Downtown
4.0 star property
Downtown St. Louis
8.2 out of 10, Very Good, (108)
"Great staff, comfy bed, good food!"
United States
Jeanine
Le Meridien St. Louis Downtown

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station
3.0 star property
Downtown West
8.8 out of 10, Excellent, (1763)
"Clean rooms, friendly staff, pool was awesome, breakfast was delicious breakfast with lots to choose from. "
United States
Necia
The price is NT$2,948
NT$3,447 total
includes taxes & fees
Dec 22 - Dec 23
Pear Tree Inn St. Louis Near Union Station

OYO Hotel St. Louis Downtown City Center MO

OYO Hotel St. Louis Downtown City Center MO
3.5 star property
Downtown West
6.6 out of 10, (1000)
"Wonderful stay."
United States
Anonymous traveler
OYO Hotel St. Louis Downtown City Center MO

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1244)
"Great hospitality"
United States
Alejandro
The price is NT$3,447
NT$4,099 total
includes taxes & fees
Dec 25 - Dec 26
Embassy Suites by Hilton St. Louis Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Downtown St. Louis

Downtown St. Louisand its attractions for luxury travelers

Downtown St. Louis is a vibrant hub that caters to luxury travelers seeking both culture and comfort. Start your journey at the iconic Gateway Arch, where you can take a tram ride to the top for stunning views of the cityscape and the Mississippi River. Just a short stroll away, the City Museum offers a unique blend of art and amusement, featuring whimsical installations made from repurposed architectural elements, perfect for the adventurous family seeking a creative outing. For a taste of St. Louis’s rich history, the Missouri History Museum showcases fascinating exhibits that delve into the city's past, making it a great educational stop for both adults and children. After a day of exploration, indulge in a culinary experience at one of the upscale restaurants nearby, such as Tony's, renowned for its exquisite Italian dishes and elegant ambiance. Finally, unwind at luxury hotels in the area, where you can expect personalized service, spacious rooms with city views, and amenities like rooftop pools or spa services, ensuring a memorable stay that caters to your every need.

Find the best luxury hotels and resorts in Downtown St. Louis

For those seeking a luxurious stay in Downtown St. Louis, these hotels offer exquisite amenities and exceptional service, ensuring a memorable experience for travelers.

Live by Loews - St.Louis

  • Why it's great for a luxury retreat: With an impressive review rating of 9.2, Live by Loews - St. Louis is designed for luxury travelers who appreciate modern elegance. The hotel offers valet parking and plush bathrobes for guests to enjoy during their stay. The attentive concierge service is on hand to assist with any requests, ensuring a seamless experience in the heart of the city.
  • Other amenities: Guests can take advantage of air-conditioned rooms and daily housekeeping for an enhanced stay. The hotel features a rooftop terrace where travelers can unwind and enjoy the view. Self-parking options are available for convenience, and the hotel includes a grocery and convenience store for easy access to essentials. Fitness facilities are open for guests looking to stay active, while child-friendly window designs enhance safety without compromising style.
  • Neighborhood: Downtown St. Louis
  • Nearby attractions: Busch Stadium - 0.04 miles, America's Center Convention Complex - 0.63 miles, Enterprise Center - 0.48 miles

Live by Loews - St.Louis

  • Why it's great for a luxury retreat: Live by Loews - St. Louis is an exceptional choice for luxury travelers, featuring a stellar review rating of 9.2. The hotel offers valet parking services and luxurious bathrobes for added comfort, alongside personalized concierge assistance to cater to every need. Travelers can enjoy the air-conditioned rooms that promise a refreshing retreat after a day of exploring the city.
  • Other amenities: Other noteworthy features include a charming terrace, daily housekeeping for a pristine environment, and easy access to nearby attractions. Guests can also take advantage of covered self-parking, a grocery convenience store for snacks, and the hotel’s elegant design that reflects the vibrant spirit of St. Louis.
  • Neighborhood: Downtown St. Louis
  • Nearby attractions: Busch Stadium - 0.04 miles, America's Center Convention Complex - 0.63 miles, Enterprise Center - 0.48 miles

21C Museum Hotel St Louis

  • Why it's great for a luxury retreat: 21C Museum Hotel St. Louis offers a unique blend of luxury and culture, receiving an impressive review rating of 9.0. This hotel features upscale amenities such as plush bathrobes, valet parking for convenience, and attentive concierge services. Guests can unwind in stylishly appointed rooms, equipped with air conditioning for a comfortable stay.
  • Other amenities: Additional amenities include an indoor pool for refreshing swims, an onsite spa offering various treatments, and a fitness center suitable for maintaining workout routines. The hotel also features daily housekeeping, complimentary toiletries, and a billiards area for leisurely entertainment, making it an ideal choice for those looking to indulge in a luxurious experience.
  • Neighborhood: Downtown West
  • Nearby attractions: City Museum - 0.33 miles, St. Louis Union Station - 0.42 miles, Enterprise Center - 0.4 miles

Embassy Suites by Hilton St. Louis Downtown

  • Why it's great for a luxury retreat: Embassy Suites by Hilton St. Louis Downtown epitomizes luxury with its outstanding features and a solid review rating of 8.6. Guests can enjoy premium bedding and secured valet parking, ensuring a restful and straightforward stay. The hotel also offers champagne service to celebrate special occasions, alongside spacious suites that provide an extra touch of elegance.
  • Other amenities: Additional offerings include a complimentary breakfast to start the day right, an indoor pool for relaxation, and electric car charging stations for eco-conscious travelers. The hotel’s fitness center is accessible for those wishing to maintain their routines, while the inviting atmosphere makes it a perfect retreat after a day of exploration.
  • Neighborhood: Downtown St. Louis
  • Nearby attractions: America's Center Convention Complex - 0.09 miles, Dome at America’s Center - 0.13 miles, Horseshoe St. Louis Casino - 0.49 miles

Embassy Suites by Hilton St. Louis Downtown

  • Why it's great for a luxury retreat: The Embassy Suites by Hilton St. Louis Downtown shines with a review rating of 8.6, making it an excellent choice for luxury travelers. This elegant hotel provides premium bedding for a restful night's sleep, along with secured valet parking for peace of mind. Guests can indulge in champagne service, adding a touch of celebration to any stay.
  • Other amenities: The hotel features indoor pools for relaxation and a complimentary breakfast that elevates the morning experience. Guests will appreciate the spacious suites with separate living rooms and early check-in options. Fitness enthusiasts can make use of the accessible fitness center, while complimentary toiletries enhance the luxurious experience. The hotel also offers electric car charging stations, ensuring convenience for eco-conscious travelers.
  • Neighborhood: Downtown St. Louis
  • Nearby attractions: America's Center Convention Complex - 0.09 miles, Dome at America’s Center - 0.13 miles, Horseshoe St. Louis Casino - 0.49 miles

Top Downtown St. Louis Hotel Reviews

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Downtown St. Louis?
Known for its museums and entertainment, Downtown St. Louis also has some interesting things to see and do including Gateway Arch, so you may want to take in the local sights during your visit.
What's the best luxury hotel in Downtown St. Louis?
Four Seasons Hotel St Louis is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is The Westin St. Louis.
What's there to see and do in Downtown St. Louis?
Take in the sights and attractions that Downtown St. Louis offers with a visit to Gateway Arch, Gateway Arch National Park, and Kiener Plaza. If you have extra time while you're in the area, you might want to see Museum at the Gateway Arch and Ballpark Village.
How can I get around Downtown St. Louis?
It's easier to get around town in style when you know your options. Nearby metro stations include 8th and Pine Station, Stadium Station, and Convention Center Station.

Explore a world of travel with Expedia