
Downtown St. Louis Vacations
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Where to stay in Downtown St. Louis
Find the best Downtown St. Louis areas and neighborhoods for the activities you enjoy most. Learn more about Downtown St. Louis

Clayton
1 out of top 10 points of interest in this area
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Downtown St. Louis Hotel Deals

Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
The price is NT$4,009 per night from May 25 to May 26
NT$4,009
NT$4,728 total
May 25 - May 26
includes taxes & fees
8.6/10 Excellent! (4,056 reviews)
"Nice"
Reviewed on 2026/5/21

Live by Loews - St.Louis
799 Clark ave St. Louis MO
The price is NT$5,033 per night from May 24 to May 25
NT$5,033
NT$5,986 total
May 24 - May 25
includes taxes & fees
9.4/10 Exceptional! (1,174 reviews)
"Live by Loews always goes above and beyond."
Reviewed on 2026/5/21

Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is NT$5,381 per night from May 22 to May 23
NT$5,381
NT$6,292 total
May 22 - May 23
includes taxes & fees
9.6/10 Exceptional! (3,429 reviews)
"Great hotel. Wonderful breakfast. A lot of choices. Hot tub was nice. Very nice room."
Reviewed on 2026/5/20
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover the most popular places to visit in Downtown St. Louis

Gateway Arch
4.5/5(2,542 reviews)
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Dome at America’s Center
4/5(538 reviews)
Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's fascinating museums and acclaimed art scene.

Gateway Arch National Park
This central park houses the Gateway Arch, Museum of Westward Expansion and Old Courthouse, and is a popular starting point for exploring the Mississippi River.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.



