The Best Business Hotels in St. Louis, MO from NT$3,370 in 2026

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Our top choices for St. Louis business-friendly hotels

1. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis

Salvatore

NT$4,293

NT$5,020 total

includes taxes & fees

Oct 18 - Oct 19

2. Pear Tree Inn St. Louis Airport

St. Ann

Monica

NT$2,862

NT$3,370 total

includes taxes & fees

Oct 18 - Oct 19

Premium bedding, in-room safe, desk, laptop workspace

3. Hyatt Regency St. Louis at The Arch

Downtown St. Louis

GLADYS

NT$4,838

NT$5,705 total

includes taxes & fees

Oct 1 - Oct 2

Premium bedding, pillowtop beds, in-room safe, desk

4. Clayton Plaza Hotel & Extended Stay

Clayton

Sivakumar

NT$3,002

NT$3,505 total

includes taxes & fees

Oct 11 - Oct 12

Suite, Multiple Beds, Non Smoking | Desk, laptop workspace, iron/ironing board, cribs (free)

5. Wingate by Wyndham St. Louis Airport

St. Ann

Margaret

NT$3,495

NT$4,115 total

includes taxes & fees

Sep 18 - Sep 19

Desk, blackout drapes, iron/ironing board, cribs (free)

6. Drury Inn & Suites St. Louis Airport

Edmundson

Jessica

NT$3,657

NT$4,291 total

includes taxes & fees

Oct 18 - Oct 19

7. Hyatt Select St. Louis Airport

Woodson Terrace

Maxine

NT$3,499

NT$4,302 total

includes taxes & fees

Oct 4 - Oct 5

5 restaurants; breakfast, lunch, dinner, and brunch served

8. River City Casino & Hotel

St. Louis

Ashley

NT$3,262

NT$4,260 total

includes taxes & fees

Oct 12 - Oct 13

View all properties

Top St. Louis Hotel Reviews

Pear Tree Inn St. Louis Airport

10/10 Excellent

"The guy that checked us in was very pleasant. He saw that I was in a wheelchair and asked if we'd like to be moved to a handicap room. Very sweet . The hotel was clean our room was clean & the beds were SO comfortable we're definitely going back and asking for the same room. I asked if I could have a noon checkout instead of 11 due to not feeling well. The young lady at the desk said sure and hoped I feel better..A very pleasant experience."

Hyatt Regency St. Louis at The Arch

10/10 Excellent

"Great"

Drury Plaza Hotel St. Louis Union Station

8/10 Good

"The staff was stellar, answered questions before I thought of them, knew the area and were efficient, housekeeping staff offered help and suggestions and were a highlight but front desk staff was great too. The parking garage was adequate, but parking before you checked in wasn't great (they offered a few 15 minute stalls and most folks clogged up the entrance area after that, so a bit cramped), but the garage itself wasn't bad. Room was clean, was were the public areas. Overall a nice stay!."

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"Great location, very clean. Highly recommend!"

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent

"We will stay here again. Good bkfst, convenient. Nice pool & spa."

Clayton Plaza Hotel & Extended Stay

10/10 Excellent

"We enjoyed the hotel. Lobby was beautiful and staff was helpful."

Courtyard by Marriott St. Louis Downtown/Convention Center

8/10 Good

"Decent hotel. Friendly staff. Not much for their snack area, but you're near many restaurants."

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent

"Room was clean and comfy. Breakfast was Delicious 😋"

Sonesta ES Suites St. Louis - Chesterfield

10/10 Excellent

"Enjoyed my 4 night stay at Sonesta in Chersterfield Missouri. The location was really good and easy to get to. The staff were all very friendly and helpful. Breakfast was good and the pool was fun to hang out at. My son enjoyed the workout room too."

Frequently asked questions

How much do business-friendly hotels in St. Louis cost?

You can expect to pay between NT$3,370 and NT$5,705 per night for business-friendly hotels in St. Louis. Awesome deals on properties that are suitable for work-related guests are just a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the best business-friendly hotels in St. Louis?

A lot of corporate travelers recommend Drury Inn & Suites St. Louis Brentwood. This 3-stars property offers amenities such as a swimming pool and WiFi. Drury Plaza Hotel St. Louis at the Arch is another sought-after option. It has a 3-stars rating and conveniences including a swimming pool and a terrace. You'll have your pick of multiple business-friendly hotels in St. Louis that have a total average guest review rating of 9.0.

How many business-friendly hotels are there in St. Louis?

When your job takes you on the road in St. Louis, you'll have 195 business-friendly hotels to pick from. These stays offer a well-suited location with the conveniences corporate travelers need.

What are the best cheap business-friendly hotels in St. Louis?

Save money on your work trip to St. Louis by choosing one of our business-friendly hotels that start from only NT$3,370 per night. One inexpensive property is Hampton Inn & Suites St. Louis at Forest Park, which comes with amenities like a swimming pool and pillow top mattresses. Hampton Inn St. Louis-Downtown (At the Gateway Arch) is another leading pick for corporate travelers with a tight budget. It features pool sun loungers and an electric car charging station. However, your St. Louis visit shouldn't be all work and no play. Explore some fun and free attractions, such as Forest Park and Anheuser-Busch Brewery. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

Are there any family-friendly hotels in St. Louis that are also business friendly?

Drury Plaza Hotel St. Louis at the Arch is popular with both business and leisure guests. Complimentary breakfast and WiFi are just a couple of the amenities available at this 3-stars St. Louis escape. Alternatively, vacation with the family and get down to work at Drury Inn & Suites St. Louis Forest Park. Enjoy the use of conveniences such as complimentary breakfast and housekeeping services at this top 3-stars option. St. Louis has tons of family-friendly attractions to check out when you're done with work. Take the kids on an outing to St. Louis Zoo and Forest Park.

Are there any 5-star business-friendly hotels in St. Louis?

St. Louis has some great 5-star options for corporate guests. Enjoy luxury perks after a busy day with clients at Four Seasons Hotel St Louis. Amenities at this business-friendly stay, around 2 kilometers from St. Louis's center, include a sauna and treatment rooms. Another high-end property that has everything you need for a work trip is The Ritz-Carlton, St. Louis. It features designer toiletries and concierge services and is 11 kilometers from the downtown area.

Why book your business-friendly hotel in St. Louis with Expedia?

With useful amenities like conference rooms, 24-hour front desk support and free parking, our business-friendly hotels come with all you'll need to settle that big contract — and then relax in the comfort of your room. Enter your preferred dates and travel destination and Expedia will help you plan the rest.

How can I find cheap business-friendly hotels in St. Louis?

Select the "business friendly" filter, listed just under the "traveler experience" heading, to find cheap business-friendly hotels in St. Louis. Then narrow your search by your budget and preferred hotel star rating. Looking for stays away from the center is another easy way to save.

What is there to do in St. Louis near my business-friendly hotel?

Whatever you love to do, St. Louis has a whole lot to keep you on the go. St. Louis Zoo, Forest Park and Fox Theater are on most visitors' sightseeing plans. Don't head home without exploring Anheuser-Busch Brewery, St. Louis Aquarium at Union Station and St. Louis Science Center either. With Expedia's business-friendly hotel deals, you can discover more renowned attractions like these with the cash you save.

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Book Business Hotels in St. Louis on Expedia.com

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Change your mind

Treat yourself

Be picky

Check availability on St. Louis Business Hotels

Our top choices for St. Louis business-friendly hotels

1. Drury Plaza Hotel St. Louis at the Arch

2. Pear Tree Inn St. Louis Airport

3. Hyatt Regency St. Louis at The Arch

4. Clayton Plaza Hotel & Extended Stay

5. Wingate by Wyndham St. Louis Airport

6. Drury Inn & Suites St. Louis Airport

7. Hyatt Select St. Louis Airport

8. River City Casino & Hotel

9. Embassy Suites by Hilton St. Louis Downtown

10. Holiday Inn Express & Suites St. Louis West - Fenton by IHG

Top St. Louis Hotel Reviews

Pear Tree Inn St. Louis Airport

Hyatt Regency St. Louis at The Arch

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis at the Arch

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Clayton Plaza Hotel & Extended Stay

Courtyard by Marriott St. Louis Downtown/Convention Center

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Sonesta ES Suites St. Louis - Chesterfield

Frequently asked questions

Explore a world of travel with Expedia

Find Business Hotels in St. Louis, MO

Change your mind

Treat yourself

Be picky

Check availability on St. Louis Business Hotels

Our top choices for St. Louis business-friendly hotels

1. Drury Plaza Hotel St. Louis at the Arch

2. Pear Tree Inn St. Louis Airport

3. Hyatt Regency St. Louis at The Arch

4. Clayton Plaza Hotel & Extended Stay

5. Wingate by Wyndham St. Louis Airport

6. Drury Inn & Suites St. Louis Airport

7. Hyatt Select St. Louis Airport

8. River City Casino & Hotel

9. Embassy Suites by Hilton St. Louis Downtown

10. Holiday Inn Express & Suites St. Louis West - Fenton by IHG

Top St. Louis Hotel Reviews

Pear Tree Inn St. Louis Airport

Hyatt Regency St. Louis at The Arch

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis at the Arch

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Clayton Plaza Hotel & Extended Stay

Courtyard by Marriott St. Louis Downtown/Convention Center

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Sonesta ES Suites St. Louis - Chesterfield

Frequently asked questions

Explore a world of travel with Expedia