The Best Business Hotels in St. Louis, MO from NT$2,629 in 2026

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Our top choices for St. Louis business-friendly hotels

1. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis

Salvatore

NT$4,272

NT$4,995 total

includes taxes & fees

Oct 4 - Oct 5

Room, 2 Queen Beds | Desk, blackout drapes, iron/ironing board, rollaway beds (surcharge)

2. Pear Tree Inn St. Louis Airport

St. Ann

Monica

NT$2,839

NT$3,343 total

includes taxes & fees

Sep 20 - Sep 21

Premium bedding, in-room safe, desk, laptop workspace

3. Hyatt Regency St. Louis at The Arch

Downtown St. Louis

TRACY

NT$4,813

NT$5,676 total

includes taxes & fees

Oct 4 - Oct 5

Premium bedding, pillowtop beds, in-room safe, desk

4. Clayton Plaza Hotel & Extended Stay

Clayton

Sivakumar

NT$3,009

NT$3,513 total

includes taxes & fees

Oct 11 - Oct 12

5 restaurants; breakfast, lunch, dinner, and brunch served

5. River City Casino & Hotel

St. Louis

Ashley

NT$3,038

NT$3,996 total

includes taxes & fees

Oct 6 - Oct 7

Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave | Desk, blackout drapes, iron/ironing board, cribs (free)

6. Best Western St. Louis Inn

St. Louis

Bryan

NT$2,286

NT$2,629 total

includes taxes & fees

Sep 13 - Sep 14

Room, 2 Queen Beds | Desk, blackout drapes, iron/ironing board, cribs (free)

7. Drury Plaza Hotel St. Louis Union Station

Downtown West

Katy

NT$4,259

NT$5,065 total

includes taxes & fees

Sep 20 - Sep 21

Deluxe Room, 2 Queen Beds, Non Smoking | Living area | TV

8. Missouri Athletic Club

Downtown St. Louis

Jill

NT$4,130

NT$4,829 total

includes taxes & fees

Sep 14 - Sep 15

View all properties

Top St. Louis Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent

"Best place for family, enjoyed the stay"

Clayton Plaza Hotel & Extended Stay

8/10 Good

"I would stay again."

Pear Tree Inn St. Louis Airport

10/10 Excellent

"I loved they will take you almost anywhere you want. Check out the metro to get you through the city $5 for 24 hours. Hotel will take you and pick you up from airport where it begins."

Hollywood Casino & Hotel St. Louis

8/10 Good

"We had a nice time at the resort and the staff were friendly and helpful. Not many complaints but the room smelled like it had been smoked in for years but they painted the walls to cover it up. Other than that it’s a fine place to stay for a concert."

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"Check in was easy & quick. We were running late but timed it just right since dinner was being served. We were able to make it to the concert in time. We normally stay at the Drury hotel if there is one in the area. It is very convenient to be able to eat dinner & breakfast were we stay. Thank you to the staff for being very helpful."

Forest Park Hotel by MDR

8/10 Good

"Nice clean room. Pool was closed , was looking forward to it, wish they served breakfast as well. But over all a great stay at a good price."

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

8/10 Good

"I have stayed at this hotel a few times. The value is good - a better than expected hotel for the price. There were 2 issues for this last stay. I had a room with an adjacent wall to the elevator area, and the elevator is very loud and clunky when the door opens and shuts. I could hear it all day and all night long (good thing I had good earplugs). Make sure to get a room away from the elevator. Also, the cable tv system is a mess. The channels don't match what the cable guide on the TV says nor what the icon in the corner of the screen says. Also, many of the channels they're supposed to have say "no signal." Not a huge deal but definitely annoying. A simple piece of paper in the room which lists the real channels would certainly help."

Frequently asked questions

How much do business-friendly hotels in St. Louis cost?

You can expect to pay between NT$2,629 and NT$5,676 per night for business-friendly hotels in St. Louis. Awesome deals on properties that are suitable for work-related guests are just a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the best business-friendly hotels in St. Louis?

A lot of corporate travelers recommend Drury Inn & Suites St. Louis Brentwood. This 3-stars property offers amenities such as a swimming pool and WiFi. Drury Plaza Hotel St. Louis at the Arch is another sought-after option. It has a 3-stars rating and conveniences including a swimming pool and a terrace. You'll have your pick of multiple business-friendly hotels in St. Louis that have a total average guest review rating of 8.9.

How many business-friendly hotels are there in St. Louis?

When your job takes you on the road in St. Louis, you'll have 195 business-friendly hotels to pick from. These stays offer a well-suited location with the conveniences corporate travelers need.

What are the best cheap business-friendly hotels in St. Louis?

Save money on your work trip to St. Louis by choosing one of our business-friendly hotels that start from only NT$2,629 per night. One inexpensive property is Hampton Inn & Suites St. Louis at Forest Park, which comes with amenities like a swimming pool and pillow top mattresses. Hampton Inn St. Louis-Downtown (At the Gateway Arch) is another leading pick for corporate travelers with a tight budget. It features pool sun loungers and an electric car charging station. However, your St. Louis visit shouldn't be all work and no play. Explore some fun and free attractions, such as Forest Park and Anheuser-Busch Brewery. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

Are there any family-friendly hotels in St. Louis that are also business friendly?

Drury Plaza Hotel St. Louis at the Arch is popular with both business and leisure guests. Complimentary breakfast and WiFi are just a couple of the amenities available at this 3-stars St. Louis escape. Alternatively, vacation with the family and get down to work at Drury Inn & Suites St. Louis Forest Park. Enjoy the use of conveniences such as complimentary breakfast and housekeeping services at this top 3-stars option. St. Louis has tons of family-friendly attractions to check out when you're done with work. Take the kids on an outing to St. Louis Zoo and Forest Park.

Are there any 5-star business-friendly hotels in St. Louis?

St. Louis has some great 5-star options for corporate guests. Enjoy luxury perks after a busy day with clients at Four Seasons Hotel St Louis. Amenities at this business-friendly stay, around 2 kilometers from St. Louis's center, include a sauna and treatment rooms. Another high-end property that has everything you need for a work trip is The Ritz-Carlton, St. Louis. It features designer toiletries and concierge services and is 11 kilometers from the downtown area.

Why book your business-friendly hotel in St. Louis with Expedia?

With useful amenities like conference rooms, 24-hour front desk support and free parking, our business-friendly hotels come with all you'll need to settle that big contract — and then relax in the comfort of your room. Enter your preferred dates and travel destination and Expedia will help you plan the rest.

How can I find cheap business-friendly hotels in St. Louis?

Select the "business friendly" filter, listed just under the "traveler experience" heading, to find cheap business-friendly hotels in St. Louis. Then narrow your search by your budget and preferred hotel star rating. Looking for stays away from the center is another easy way to save.

What is there to do in St. Louis near my business-friendly hotel?

Whatever you love to do, St. Louis has a whole lot to keep you on the go. St. Louis Zoo, Forest Park and Fox Theater are on most visitors' sightseeing plans. Don't head home without exploring Anheuser-Busch Brewery, St. Louis Aquarium at Union Station and St. Louis Science Center either. With Expedia's business-friendly hotel deals, you can discover more renowned attractions like these with the cash you save.

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Treat yourself

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Check availability on St. Louis Business Hotels

Our top choices for St. Louis business-friendly hotels

1. Drury Plaza Hotel St. Louis at the Arch

2. Pear Tree Inn St. Louis Airport

3. Hyatt Regency St. Louis at The Arch

4. Clayton Plaza Hotel & Extended Stay

5. River City Casino & Hotel

6. Best Western St. Louis Inn

7. Drury Plaza Hotel St. Louis Union Station

8. Missouri Athletic Club

9. The Wildwood Hotel

10. Hilton Pennywell St. Louis at the Arch

Top St. Louis Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

Clayton Plaza Hotel & Extended Stay

Pear Tree Inn St. Louis Airport

Hollywood Casino & Hotel St. Louis

Drury Plaza Hotel St. Louis at the Arch

Forest Park Hotel by MDR

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Frequently asked questions

Explore a world of travel with Expedia

Find Business Hotels in St. Louis, MO

Change your mind

Treat yourself

Be picky

Check availability on St. Louis Business Hotels

Our top choices for St. Louis business-friendly hotels

1. Drury Plaza Hotel St. Louis at the Arch

2. Pear Tree Inn St. Louis Airport

3. Hyatt Regency St. Louis at The Arch

4. Clayton Plaza Hotel & Extended Stay

5. River City Casino & Hotel

6. Best Western St. Louis Inn

7. Drury Plaza Hotel St. Louis Union Station

8. Missouri Athletic Club

9. The Wildwood Hotel

10. Hilton Pennywell St. Louis at the Arch

Top St. Louis Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

Clayton Plaza Hotel & Extended Stay

Pear Tree Inn St. Louis Airport

Hollywood Casino & Hotel St. Louis

Drury Plaza Hotel St. Louis at the Arch

Forest Park Hotel by MDR

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Frequently asked questions

Explore a world of travel with Expedia