The Best Business Hotels in St. Louis, MO from NT$2,621 in 2026

A large white building with a dome and a statue in front, surrounded by fountains and trees.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check availability on St. Louis Business Hotels

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for St. Louis business-friendly hotels

1. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis

Salvatore

NT$4,259

NT$4,980 total

includes taxes & fees

Oct 4 - Oct 5

2. Pear Tree Inn St. Louis Airport

St. Ann

Monica

NT$2,832

NT$3,334 total

includes taxes & fees

Sep 15 - Sep 16

3. Hyatt Regency St. Louis at The Arch

Downtown St. Louis

TRACY

NT$4,799

NT$5,659 total

includes taxes & fees

Oct 4 - Oct 5

4. Clayton Plaza Hotel & Extended Stay

Clayton

Sivakumar

NT$3,000

NT$3,503 total

includes taxes & fees

Oct 11 - Oct 12

5. River City Casino & Hotel

St. Louis

Ashley

NT$3,029

NT$3,984 total

includes taxes & fees

Oct 6 - Oct 7

6. Best Western St. Louis Inn

St. Louis

Bryan

NT$2,279

NT$2,621 total

includes taxes & fees

Sep 13 - Sep 14

7. Drury Plaza Hotel St. Louis Union Station

Downtown West

Katy

NT$4,248

NT$5,052 total

includes taxes & fees

Sep 20 - Sep 21

Deluxe Room, 2 Queen Beds, Non Smoking | Living area

8. Missouri Athletic Club

Downtown St. Louis

Jill

NT$4,117

NT$4,814 total

includes taxes & fees

Sep 14 - Sep 15

View all properties

Top St. Louis Hotel Reviews

Pear Tree Inn St. Louis Airport

10/10 Excellent

"Good"

Hollywood Casino & Hotel St. Louis

10/10 Excellent

"Awesome service it was all around the best, they staff was very nice and friendly and very helpful"

Hyatt Regency St. Louis at The Arch

10/10 Excellent

"We loved the clean, comfortable room and friendly staff. At check in, the front desk provides an area map to the guests, which is very helpful. The location is great...walking distance to several sites, including Busch Stadium. Our only complaint was the poor water pressure in the shower, which really is not a deal breaker. We had a short stay and did not get to experience all the amenities, but we will definitely be back!"

Clayton Plaza Hotel & Extended Stay

8/10 Good

"Free breakfast Free parking Pool Fridge Microwave"

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"Location fit my needs perfectly. The entire staff was excellent. Will definitely stay here when in St. Louis"

Hilton St. Louis at the Ballpark

10/10 Excellent

"Perfect location. Close to everything. Staff were very friendly and helpful."

Forest Park Hotel by MDR

8/10 Good

"Nice clean room. Pool was closed , was looking forward to it, wish they served breakfast as well. But over all a great stay at a good price."

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

8/10 Good

"I have stayed at this hotel a few times. The value is good - a better than expected hotel for the price. There were 2 issues for this last stay. I had a room with an adjacent wall to the elevator area, and the elevator is very loud and clunky when the door opens and shuts. I could hear it all day and all night long (good thing I had good earplugs). Make sure to get a room away from the elevator. Also, the cable tv system is a mess. The channels don't match what the cable guide on the TV says nor what the icon in the corner of the screen says. Also, many of the channels they're supposed to have say "no signal." Not a huge deal but definitely annoying. A simple piece of paper in the room which lists the real channels would certainly help."

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent

"Awesome loved everything"

Frequently asked questions

How much do business-friendly hotels in St. Louis cost?

You can expect to pay between NT$2,621 and NT$5,659 per night for business-friendly hotels in St. Louis. Awesome deals on properties that are suitable for work-related guests are just a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the best business-friendly hotels in St. Louis?

A lot of corporate travelers recommend Drury Inn & Suites St. Louis Brentwood. This 3-stars property offers amenities such as a swimming pool and WiFi. Drury Plaza Hotel St. Louis at the Arch is another sought-after option. It has a 3-stars rating and conveniences including a swimming pool and a terrace. You'll have your pick of multiple business-friendly hotels in St. Louis that have a total average guest review rating of 8.9.

How many business-friendly hotels are there in St. Louis?

When your job takes you on the road in St. Louis, you'll have 195 business-friendly hotels to pick from. These stays offer a well-suited location with the conveniences corporate travelers need.

What are the best cheap business-friendly hotels in St. Louis?

Save money on your work trip to St. Louis by choosing one of our business-friendly hotels that start from only NT$2,621 per night. One inexpensive property is Hampton Inn & Suites St. Louis at Forest Park, which comes with amenities like a swimming pool and pillow top mattresses. Hampton Inn St. Louis-Downtown (At the Gateway Arch) is another leading pick for corporate travelers with a tight budget. It features pool sun loungers and an electric car charging station. However, your St. Louis visit shouldn't be all work and no play. Explore some fun and free attractions, such as Forest Park and Anheuser-Busch Brewery. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

Are there any family-friendly hotels in St. Louis that are also business friendly?

Drury Plaza Hotel St. Louis at the Arch is popular with both business and leisure guests. Complimentary breakfast and WiFi are just a couple of the amenities available at this 3-stars St. Louis escape. Alternatively, vacation with the family and get down to work at Drury Inn & Suites St. Louis Forest Park. Enjoy the use of conveniences such as complimentary breakfast and housekeeping services at this top 3-stars option. St. Louis has tons of family-friendly attractions to check out when you're done with work. Take the kids on an outing to St. Louis Zoo and Forest Park.

Are there any 5-star business-friendly hotels in St. Louis?

St. Louis has some great 5-star options for corporate guests. Enjoy luxury perks after a busy day with clients at Four Seasons Hotel St Louis. Amenities at this business-friendly stay, around 2 kilometers from St. Louis's center, include a sauna and treatment rooms. Another high-end property that has everything you need for a work trip is The Ritz-Carlton, St. Louis. It features designer toiletries and concierge services and is 11 kilometers from the downtown area.

Why book your business-friendly hotel in St. Louis with Expedia?

With useful amenities like conference rooms, 24-hour front desk support and free parking, our business-friendly hotels come with all you'll need to settle that big contract — and then relax in the comfort of your room. Enter your preferred dates and travel destination and Expedia will help you plan the rest.

How can I find cheap business-friendly hotels in St. Louis?

Select the "business friendly" filter, listed just under the "traveler experience" heading, to find cheap business-friendly hotels in St. Louis. Then narrow your search by your budget and preferred hotel star rating. Looking for stays away from the center is another easy way to save.

What is there to do in St. Louis near my business-friendly hotel?

Whatever you love to do, St. Louis has a whole lot to keep you on the go. St. Louis Zoo, Forest Park and Fox Theater are on most visitors' sightseeing plans. Don't head home without exploring Anheuser-Busch Brewery, St. Louis Aquarium at Union Station and St. Louis Science Center either. With Expedia's business-friendly hotel deals, you can discover more renowned attractions like these with the cash you save.

Explore a world of travel with Expedia

Book Business Hotels in St. Louis on Expedia.com

Room 1

Change your mind

Treat yourself

Be picky

Check availability on St. Louis Business Hotels

Our top choices for St. Louis business-friendly hotels

1. Drury Plaza Hotel St. Louis at the Arch

2. Pear Tree Inn St. Louis Airport

3. Hyatt Regency St. Louis at The Arch

4. Clayton Plaza Hotel & Extended Stay

5. River City Casino & Hotel

6. Best Western St. Louis Inn

7. Drury Plaza Hotel St. Louis Union Station

8. Missouri Athletic Club

9. The Wildwood Hotel

10. Hilton Pennywell St. Louis at the Arch

Top St. Louis Hotel Reviews

Pear Tree Inn St. Louis Airport

Hollywood Casino & Hotel St. Louis

Hyatt Regency St. Louis at The Arch

Clayton Plaza Hotel & Extended Stay

Drury Plaza Hotel St. Louis at the Arch

Hilton St. Louis at the Ballpark

Forest Park Hotel by MDR

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Frequently asked questions

Explore a world of travel with Expedia

Find Business Hotels in St. Louis, MO

Change your mind

Treat yourself

Be picky

Check availability on St. Louis Business Hotels

Our top choices for St. Louis business-friendly hotels

1. Drury Plaza Hotel St. Louis at the Arch

2. Pear Tree Inn St. Louis Airport

3. Hyatt Regency St. Louis at The Arch

4. Clayton Plaza Hotel & Extended Stay

5. River City Casino & Hotel

6. Best Western St. Louis Inn

7. Drury Plaza Hotel St. Louis Union Station

8. Missouri Athletic Club

9. The Wildwood Hotel

10. Hilton Pennywell St. Louis at the Arch

Top St. Louis Hotel Reviews

Pear Tree Inn St. Louis Airport

Hollywood Casino & Hotel St. Louis

Hyatt Regency St. Louis at The Arch

Clayton Plaza Hotel & Extended Stay

Drury Plaza Hotel St. Louis at the Arch

Hilton St. Louis at the Ballpark

Forest Park Hotel by MDR

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Frequently asked questions

Explore a world of travel with Expedia