Clayton Vacations
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- Plan, book, travel with confidence
- Better togetherSave up to NT$25,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
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Where to stay in Clayton
Find the best Clayton areas and neighborhoods for the activities you enjoy most. Learn more about Clayton
Downtown St. Louis
4 out of top 10 points of interest in this area
Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
St. Charles Historic District
Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
Downtown West
2 out of top 10 points of interest in this area
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
Clayton Hotel Deals
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
NT$2,919
NT$3,408 total
Oct 25 - Oct 26
includes taxes & fees
8.8/10 Excellent! (3,451 reviews)
"Nice place for me and my daughter to stay, felt safe and the pool was warm."
Reviewed on 2026/10/4
AC Hotel St. Louis Clayton
227 South Central Ave St. Louis MO
Fully refundableReserve now, pay when you stay
NT$4,091
NT$4,775 total
Oct 18 - Oct 19
includes taxes & fees
Le Méridien St. Louis Clayton
7730 Bonhomme Ave St. Louis MO
Fully refundableReserve now, pay when you stay
NT$4,848
NT$5,708 total
Oct 11 - Oct 12
includes taxes & fees
8.8/10 Excellent! (784 reviews)
"Room was smaller than I expected. Staffs were very kind and helpful."
Reviewed on 2026/10/2
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Clayton vacation package cost?
From as little as , you can tailor make your Clayton vacation package. Simply combine hotels, flights and rental cars and be rewarded with discounts.
How do I get a cheap travel package to Clayton?
By bundling. Flights, hotels and rental cars — combine whatever you need into a Clayton vacation package to save a pile of cash. Score even more discounts when you include extras such as tours or experiences to your booking. But that's not the only good part. You have the freedom to customize your trip your own way. We offer over 550 air carriers and 1,000,000 properties across the globe, so that everyone has a chance to travel and fulfill those vacation dreams.
Where should I stay in Clayton?
With so much to discover in Clayton, it'd be convenient for you to secure a room in a hotel close to its attractions. St. Louis Zoo, Washington University in St. Louis and Forest Park are some good ones to put on your must-see list.
What are the top hotels in Clayton?
If it's your first time staying in Clayton, secure a room at King Bed, Comfy Environment, Cozy Space or Homewood Suites by Hilton St Louis - Galleria. Both hotels offer friendly service and are top options with many savvy travelers.
How far in advance should I book my Clayton vacation?
It's difficult to pick the ideal time for airfares, but we usually say the earlier, the better. Most international flights on Expedia become available to compare up to 12 months in advance. If you're unable to do so, don't despair. Low prices appear from time to time just weeks before departure dates.
What does an Expedia Clayton travel package include?
With Expedia, you can select any combination of flights, hotels and car rentals to build your perfect Clayton package. Once you've made your booking, you can add on the fun things like sightseeing tours and activities. Remember, the more you bundle, the more dollars you'll save!
What should I know before booking a Clayton travel package?
Whether it's relaxation or adventure you're seeking, a Clayton vacation package lets you organize your escape your way. Plus, you'll get access to great discounts when you combine your hotel with your flights and rental car. The more you bundle, the more you'll save!
Can I choose my airline with a Clayton Expedia vacation package?
You sure can. We have more than 550 partner airlines worldwide, so fly with the carrier that's a good fit for your needs.
If I'm not able to travel, can I cancel my Clayton vacation package?
We get that the universe can throw the odd curveball. If you've booked a Clayton vacation package and need to amend or cancel it, we can help. We suggest looking up our Customer Service Portal first for information. But generally, if you've booked your package in the last 24 hours, you may be able to amend or cancel your itinerary for free. If it's been more than 24 hours, your hotel, airline or car rental company may charge a fee.
Stay near popular Clayton attractions
Chapel of St. Timothy And St. Titus, Concordia Seminary
Find out about the history of St. Louis when you take a trip to Chapel of St. Timothy And St. Titus, Concordia Seminary. Experience the area's great live music or attend a sporting event.
Shaw Park Tennis Center
Catch an event at Shaw Park Tennis Center during your trip to St. Louis. Check out the shops and top-notch restaurants in this family-friendly area.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.