Clayton 5 Stars Hotels
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Clayton 5 Star Hotels
Compare Clayton 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Clayton.

Hyatt Regency St. Louis at The Arch
315 Chestnut St, St. Louis, MO
The price is NT$3,501 per night from Aug 22 to Aug 23
NT$3,501
NT$4,129 total
Aug 22 - Aug 23
includes taxes & fees
8.4/10 Very Good! (3,861 reviews)
Still don't see what you're looking for?
See all properties in Clayton.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Clayton
Love dining out, zoos, and museums? Get away to Clayton!

Top Clayton Hotel Reviews

The Ritz-Carlton, St. Louis
10/10 Excellent
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Clayton Hotels by Star Rating
Hotels in Clayton Neighborhoods
Stay near popular Clayton attractions
- Hotels near Chapel of St. Timothy And St. Titus
- Hotels near Busch Stadium
- Hotels near St. Louis Union Station
- Hotels near Gateway Arch
- Hotels near St. Louis Zoo
- Hotels near Washington University in St. Louis
- Hotels near City Museum
- Hotels near Enterprise Center
- Hotels near Dome at America’s Center
- Hotels near Forest Park
- Hotels near Hollywood Casino Amphitheatre
- Hotels near St. Louis University
- Hotels near America's Center Convention Complex
- Hotels near Barnes Jewish Hospital
- Hotels near Mississippi River
- Hotels near Westport Plaza
- Hotels near Ameristar Casino St. Charles
- Hotels near Fox Theater
- Hotels near Hollywood Casino
- Hotels near Historic Main Street
More Hotel Options in Clayton
- Adventure Hotels in Clayton
- Boutique Hotels in Clayton
- Business Hotels in Clayton
- Cheap Hotels in Clayton
- Family Hotels in Clayton
- Golf Hotels in Clayton
- Historic Hotels in Clayton
- Hotel Wedding Venues in Clayton
- Hotel with a Concierge in Clayton
- Hotels with Bars in Clayton
- Hotels with Free Parking in Clayton
- Hotels with Hot Tubs in Clayton
- Hotels with WiFi in Clayton
- Hotels with a Pool in Clayton
- Hotels with an Indoor Pool in Clayton
- Luxury Hotels in Clayton
- Pet-friendly Hotels in Clayton
- Resorts & Hotels with Spas in Clayton
- Romantic Hotels in Clayton
- Shopping Hotels in Clayton
Explore more hotels
- Moonrise Hotel
- Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
- Hollywood Casino & Hotel St. Louis
- 21C Museum Hotel St Louis
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Best Western St. Louis-Kirkwood Route 66
- Days Inn and Suites by Wyndham St. Louis/Westport Plaza
- Hilton St. Louis at the Ballpark
- Renaissance St. Louis Airport Hotel
- Wingate by Wyndham St. Louis/Fenton Route 66
- Casino Queen Hotel
- Pear Tree Inn St. Louis Airport
- Forest Park Hotel by MDR
- DoubleTree by Hilton St. Louis Airport
- Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
- Drury Inn & Suites St. Louis Union Station
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- Ameristar Casino Resort and Spa
- Comfort Inn & Suites
- River City Casino & Hotel
More ways to book
Expedia's Latest Trends
Hotels
Flights
- Flights from Paris (CDG) to Barcelona (BCN)
- Flights from Busan (PUS) to Seoul (GMP)
- Flights from Los Angeles (LAX) to Orlando (MCO)
- Flights from Columbus (CSG) to Panama City (ECP)
- Flights from Taoyuan City (TPE) to Windsor (YQG)
- Flights from Bangkok (BKK) to Hanoi (HAN)
- Flights from Simms
- Flights from Taoyuan City (TPE) to Manila (MNL)
- Flights from Kaohsiung (KHH) to Kuching (KCH)
- Flights from Huez (AHZ) to Salt Lake City (SLC)
Vacation Rentals