Clayton, MO

St. Louis

The illuminated Gateway Arch at night with a city skyline in the background.
A city skyline with a prominent arch bridge reflecting on the water.
A city skyline with a prominent arch bridge at sunset.
A gazebo with a green roof, surrounded by a pond, with red and green foliage in the background.
A historic building with a courtyard, surrounded by lush green grass and trees.

Stay near popular Clayton attractions

Washington University in St. Louis

8.8/10 (1,777 reviews)
Enjoy the collegiate vibe at Washington University in St. Louis during your stay in St. Louis. Amble around the area's lush forest or attend a sporting event.
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Clayton Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is NT$2,917 per night from Aug 30 to Aug 31
NT$2,917
NT$3,406 total
Aug 30 - Aug 31
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Clayton Plaza Hotel & Extended Stay
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave St. Louis MO
The price is NT$4,844 per night from Aug 28 to Aug 29
NT$4,844
NT$5,704 total
Aug 28 - Aug 29
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Le Méridien St. Louis Clayton
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

3 out of 5
227 South Central Ave St. Louis MO
The price is NT$3,868 per night from Sep 13 to Sep 14
NT$3,868
NT$4,516 total
Sep 13 - Sep 14
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park ...
9.2/10 Wonderful! (368 reviews)
"Very clean. Self-parking seems a little inconvenient, but not bad when you get used to it; might want to use valet."

Reviewed on 2026/8/18

AC Hotel St. Louis Clayton
Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

3 out of 5
216 N Meramec Ave St. Louis MO
The price is NT$4,151 per night from Aug 30 to Aug 31
NT$4,151
NT$4,888 total
Aug 30 - Aug 31
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, a fitness center, and parking (surcharge). Our guests praise the helpful staff ...
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is NT$4,270 per night from Aug 28 to Aug 29
NT$4,270
NT$5,035 total
Aug 28 - Aug 29
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Hyatt Regency St. Louis at The Arch
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
The price is NT$3,180 per night from Sep 13 to Sep 14
NT$3,180
NT$4,657 total
Sep 13 - Sep 14
includes taxes & fees
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
Hollywood Casino & Hotel St. Louis
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Clayton

Find the best Clayton areas and neighborhoods for the activities you enjoy most.
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

A modern building with a brick facade, parked cars, and a flower bed with tulips.

Central West End

The ample dining options and lush forests are just a few popular features of the neighborhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.

An ornate hall with arched ceilings and intricate patterns.
Photo by Terry Eaves
Open Photo by Terry Eaves

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

A historic brick building with arched doorways and a sign that reads "Hot Goods Pen House."

St. Charles Historic District

St. Charles Historic District is known for its abundant dining options, and you can plan a trip to Historic Main Street and Missouri River while you're in town.

Clayton, MO