Popular places to visit
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
City Museum
This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.
Forest Park
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
Clayton Hotel Deals
Clayton Plaza Hotel & Extended Stay
Reviewed on 2025/10/3
AC Hotel St. Louis Clayton
Reviewed on 2025/9/30
Le Méridien St. Louis Clayton
Reviewed on 2025/9/7
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Reviewed on 2025/9/15
Drury Plaza Hotel St. Louis at the Arch
Reviewed on 2025/10/7
Hyatt Regency St. Louis at The Arch
Reviewed on 2025/10/5
Other neighborhoods around Clayton
Dogtown
If you're looking for some top things to see and do in Dogtown and surrounding area, you can visit St. Louis Zoo and St. Louis Art Museum.
University City
Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.
Ladue
The restaurants and churches are a few reasons travelers visit Ladue. Though there aren't many top sights in the neighborhood, you can visit Saint Louis Galleria Mall and St. Louis Art Museum, a few notable attractions nearby.
The Hill
If you're looking for some top things to see and do in The Hill and surrounding area, you can visit St. Louis Science Center and Missouri Botanical Gardens and Arboretum.
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
The Grove
The Grove might not have many top sights, but St. Louis Science Center and Missouri Botanical Gardens and Arboretum are two attractions nearby that you can check out.
Clayton, MO
- Places of interest
- Clayton Hotels by Star Rating
- More Hotel Options in Clayton
- Hotels in top St. Louis neighborhoods
- Gateway Arch
- St. Louis Zoo
- Enterprise Center
- Dome at America’s Center
- City Museum
- Forest Park
- Mississippi River
- America's Center Convention Complex
- Ameristar Casino St. Charles
- Barnes Jewish Hospital
- Horseshoe St. Louis Casino
- Grant's Farm
- Missouri Botanical Gardens and Arboretum
- Anheuser-Busch Brewery
- World Wide Technology Raceway
- Magic House - St. Louis Children's Museum
- Saint Louis Galleria Mall
- St. Louis Science Center
- Missouri River
More Hotel Options in Clayton
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- Golf Hotels in Clayton
- Historic Hotels in Clayton
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- Hotel with a Concierge in Clayton
- Hotels with Bars in Clayton
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- Hotels with a Pool in Clayton
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- Luxury Hotels in Clayton
- Pet-friendly Hotels in Clayton
- Resorts & Hotels with Spas in Clayton
- Romantic Hotels in Clayton
- Shopping Hotels in Clayton
