Find hotels in Southhampton, St. Louis from NT$2,377

Start date: Check-in selected.
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Sep 17 - Sep 18
Tomorrow
Sep 18 - Sep 19
This weekend
Sep 19 - Sep 21
Next weekend
Sep 26 - Sep 28

Filter by

Guest rating
Guest rating
Star rating

Discover 1,727 Southhampton hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Southhampton hotels

Drury Plaza Hotel St. Louis at the Arch
Rooftop terrace

Drury Plaza Hotel St. Louis at the Arch

3.0 star property
9.4 out of 10, Exceptional, (3058)
"Great location, great food at reception, wonderful breakfast."
The price is NT$3,608
NT$4,219 total
includes taxes & fees
Sep 28 - Sep 29
Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Airport
Lobby

Pear Tree Inn St. Louis Airport

2.5 star property
9.4 out of 10, Exceptional, (2705)
"Nice place to stay "
The price is NT$2,706
NT$3,186 total
includes taxes & fees
Sep 21 - Sep 22
Pear Tree Inn St. Louis Airport
Drury Inn & Suites St. Louis Union Station
Indoor pool

Drury Inn & Suites St. Louis Union Station

3.0 star property
9.4 out of 10, Exceptional, (1245)
" Love staying here!"
The price is NT$3,578
NT$4,255 total
includes taxes & fees
Sep 21 - Sep 22
Drury Inn & Suites St. Louis Union Station
Hyatt Regency St. Louis at The Arch
Lobby

Hyatt Regency St. Louis at The Arch

4.0 star property
8.4 out of 10, Very Good, (3979)
"Close to all events great stay"
The price is NT$3,759
NT$4,433 total
includes taxes & fees
Oct 2 - Oct 3
Hyatt Regency St. Louis at The Arch
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Lobby sitting area

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3.0 star property
8.2 out of 10, Very Good, (1010)
"Very good hotel for the price"
The price is NT$2,684
NT$3,100 total
includes taxes & fees
Sep 21 - Sep 22
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Moonrise Hotel
Exterior

Moonrise Hotel

4.0 star property
9.0 out of 10, Wonderful, (1887)
"Great atmosphere "
The price is NT$4,287
NT$5,099 total
includes taxes & fees
Oct 6 - Oct 7
Moonrise Hotel
The Wildwood Hotel
Ballroom

The Wildwood Hotel

3.5 star property
9.2 out of 10, Wonderful, (1583)
"Great place to stay."
The Wildwood Hotel
Wingate by Wyndham St. Louis Airport
Room, 2 Queen Beds, Accessible, Non Smoking (Mobility, Tub W/Grab Bars) | Desk, laptop workspace, iron/ironing board, free cribs/infant beds

Wingate by Wyndham St. Louis Airport

2.5 star property
9.2 out of 10, Wonderful, (1414)
"Great hotel I recommend 10/10"
The price is NT$3,308
NT$3,894 total
includes taxes & fees
Sep 24 - Sep 25
Wingate by Wyndham St. Louis Airport
21C Museum Hotel St Louis
Exterior

21C Museum Hotel St Louis

4.5 star property
9.0 out of 10, Wonderful, (1373)
"Amazing pool, great food and drink options, terrific staff."
The price is NT$4,575
NT$5,500 total
includes taxes & fees
Sep 21 - Sep 22
21C Museum Hotel St Louis
Embassy Suites by Hilton St. Louis Downtown
Exterior

Embassy Suites by Hilton St. Louis Downtown

4.0 star property
8.8 out of 10, Excellent, (1223)
"Had a great stay…will stay again "
The price is NT$3,495
NT$4,156 total
includes taxes & fees
Sep 28 - Sep 29
Embassy Suites by Hilton St. Louis Downtown
Pear Tree Inn St. Louis Arnold
Lobby

Pear Tree Inn St. Louis Arnold

2.5 star property
9.2 out of 10, Wonderful, (1007)
"Clean, comfortable and pleasant stay."
The price is NT$2,706
NT$3,128 total
includes taxes & fees
Sep 22 - Sep 23
Pear Tree Inn St. Louis Arnold
Clayton Plaza Hotel & Extended Stay
Exterior

Clayton Plaza Hotel & Extended Stay

3.5 star property
8.8 out of 10, Excellent, (2938)
"Its a great place to stay"
The price is NT$2,968
NT$3,457 total
includes taxes & fees
Oct 5 - Oct 6
Clayton Plaza Hotel & Extended Stay
Live by Loews - St.Louis
Breakfast, lunch and dinner served

Live by Loews - St.Louis

4.0 star property
9.2 out of 10, Wonderful, (1038)
"Great quick stay!"
The price is NT$5,082
NT$6,044 total
includes taxes & fees
Sep 28 - Sep 29
Live by Loews - St.Louis
Sonesta ES Suites St. Louis - Chesterfield
Front of property

Sonesta ES Suites St. Louis - Chesterfield

3.0 star property
8.0 out of 10, Very Good, (1007)
"Very nice place"
The price is NT$2,616
NT$3,034 total
includes taxes & fees
Oct 1 - Oct 2
Sonesta ES Suites St. Louis - Chesterfield
AC Hotel St. Louis Clayton
2 bars/lounges, rooftop bar

AC Hotel St. Louis Clayton

3.0 star property
9.2 out of 10, Wonderful, (178)
"An amazing stay!"
The price is NT$3,669
NT$4,273 total
includes taxes & fees
Oct 5 - Oct 6
AC Hotel St. Louis Clayton
The Cheshire
Terrace/patio

The Cheshire

4.0 star property
8.6 out of 10, Excellent, (1003)
"Great staff, wonderful property."
The price is NT$4,360
NT$5,177 total
includes taxes & fees
Oct 12 - Oct 13
The Cheshire
Best Western Plus St. Louis West-Westport
Lobby

Best Western Plus St. Louis West-Westport

2.5 star property
8.0 out of 10, Very Good, (1006)
"I have a pretty decent stay here"
The price is NT$2,680
NT$3,108 total
includes taxes & fees
Sep 28 - Sep 29
Best Western Plus St. Louis West-Westport
River City Casino & Hotel
Daily cooked-to-order breakfast for a fee

River City Casino & Hotel

4.0 star property
9.0 out of 10, Wonderful, (1373)
"Casino was very large and it was easy to get around. Nice casino and hotel. "
The price is NT$5,142
NT$6,430 total
includes taxes & fees
Oct 11 - Oct 12
River City Casino & Hotel
Hollywood Casino & Hotel St. Louis
Front of property - evening/night

Hollywood Casino & Hotel St. Louis

3.5 star property
8.4 out of 10, Very Good, (2144)
"Great stay!"
The price is NT$6,765
NT$8,341 total
includes taxes & fees
Sep 27 - Sep 28
Hollywood Casino & Hotel St. Louis
Wingate by Wyndham St. Louis/Fenton Route 66
Desk, blackout drapes, iron/ironing board, free cribs/infant beds

Wingate by Wyndham St. Louis/Fenton Route 66

3.0 star property
8.0 out of 10, Very Good, (1028)
"The hotel is old but the staff is friendly"
The price is NT$2,377
NT$2,745 total
includes taxes & fees
Oct 1 - Oct 2
Wingate by Wyndham St. Louis/Fenton Route 66
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Where to stay in Southhampton

Find the best Southhampton areas and neighborhoods for the activities you enjoy most.
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

3 out of top 10 points of interest in this area

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

1 out of top 10 points of interest in this area

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Central West End

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

Top Southhampton Hotel Reviews

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

10/10 Excellent
"An amazing hotel, awesome staff, and great location. Its pet friendly too"
Ayslinn 1-night trip
Posted 1 day ago
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What is Southhampton like?

Travelers to the Southhampton neighborhood in St. Louis will be sure to enjoy their stay.

How many hotels will I find in the Southhampton area?

If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 21 Southhampton hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in Southhampton, will I receive a refund?

Yes! The majority of hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to view the best deals in Southhampton.

Where can I learn more about changing or cancelling my trip to Southhampton?

To find more details about rescheduling or cancelling your trip to Southhampton, click here.

What can I see and do in this St. Louis neighborhood?

A few places to visit in the area around Southhampton include Miniature Museum of Greater St. Louis, Lindenwood Park, and River des Peres Greenway Trailhead. When you're sightseeing in St. Louis, Tower Grove Tennis Center and George Washington Carver Garden are also worth a stop.