Find hotels in Southhampton, St. Louis from NT$2,783

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Discover 1,787 Southhampton hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Drury Plaza Hotel St. Louis at the Arch

3.0 star property
Downtown St. Louis, 9.3 km from Southhampton
9.4 out of 10, Exceptional, (3297)
"Always great stay"
United States
Richard
The price is NT$4,227
NT$4,943 total
includes taxes & fees
Dec 14 - Dec 15
Drury Plaza Hotel St. Louis at the Arch

Pear Tree Inn St. Louis Airport

2.5 star property
18.4 km from Southhampton
9.4 out of 10, Exceptional, (2745)
"The room was clean and staff were very friendly."
United States
Denise
The price is NT$2,818
NT$3,318 total
includes taxes & fees
Dec 18 - Dec 19
Pear Tree Inn St. Louis Airport

Hyatt Regency St. Louis at The Arch

4.0 star property
Downtown St. Louis, 9.5 km from Southhampton
8.4 out of 10, Very Good, (3997)
"Loved our stay. Great location and awesome view from room "
United States
Phillip
The price is NT$2,959
NT$3,490 total
includes taxes & fees
Dec 23 - Dec 24
Hyatt Regency St. Louis at The Arch

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3.0 star property
16.6 km from Southhampton
8.0 out of 10, Very Good, (1024)
"Very friendly staff "
United States
Amber
The price is NT$2,669
NT$3,082 total
includes taxes & fees
Dec 14 - Dec 15
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Drury Inn & Suites St. Louis Union Station

3.0 star property
Downtown West, 7.9 km from Southhampton
9.4 out of 10, Exceptional, (1287)
"Great location and staff are friendly. "
United States
GARY
The price is NT$3,726
NT$4,432 total
includes taxes & fees
Dec 14 - Dec 15
Drury Inn & Suites St. Louis Union Station

The Wildwood Hotel

3.5 star property
30 km from Southhampton
9.2 out of 10, Wonderful, (1599)
"The hotel was amazing from the staff to the rooms. Great location as well. Definitely recommend this place if traveling! "
United States
Brandi
The price is NT$2,425
NT$2,948 total
includes taxes & fees
Dec 16 - Dec 17
The Wildwood Hotel

Moonrise Hotel

4.0 star property
7.7 km from Southhampton
9.0 out of 10, Wonderful, (1914)
"This spot is our absolute favorite when visiting StL and stay every chance we get. The surrounding area is amazing and vibrant, the hotel is extremely friendly and inviting and the rooms are great and rich with city history! Can’t wait to get back. "
United States
Brian
The price is NT$3,954
NT$4,702 total
includes taxes & fees
Dec 8 - Dec 9
Moonrise Hotel

Embassy Suites by Hilton St. Louis Downtown

4.0 star property
Downtown St. Louis, 9.5 km from Southhampton
8.8 out of 10, Excellent, (1237)
"Great hospitality"
United States
Alejandro
The price is NT$3,357
NT$3,993 total
includes taxes & fees
Dec 14 - Dec 15
Embassy Suites by Hilton St. Louis Downtown

Wingate by Wyndham St. Louis Airport

2.5 star property
18.4 km from Southhampton
9.2 out of 10, Wonderful, (1490)
"We enjoyed staying is very close to airport "
United States
Ellis
The price is NT$3,381
NT$3,980 total
includes taxes & fees
Dec 7 - Dec 8
Wingate by Wyndham St. Louis Airport

21C Museum Hotel St Louis

4.5 star property
Downtown West, 8.7 km from Southhampton
9.0 out of 10, Wonderful, (1478)
"Staff is wonderful. We checked in late after a long journey and they could not have been nicer to us at check in also in the restaurant and bar. We loved the vibe and the location. I’d return again if ever in the area. "
United States
Jenifer
The price is NT$4,777
NT$5,742 total
includes taxes & fees
Dec 28 - Dec 29
21C Museum Hotel St Louis

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4.0 star property
Downtown St. Louis, 9.4 km from Southhampton
8.8 out of 10, Excellent, (1146)
"Really nice hotel!"
United States
DARIN
The price is NT$3,163
NT$3,762 total
includes taxes & fees
Dec 18 - Dec 19
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Live by Loews - St.Louis

4.0 star property
Downtown St. Louis, 8.9 km from Southhampton
9.4 out of 10, Exceptional, (1095)
"We had an amazing view of the ballpark! The room and service was great. The restaurant and food room service were delicious! Overall great stay!"
United States
Melissa
The price is NT$4,666
NT$5,549 total
includes taxes & fees
Dec 7 - Dec 8
Live by Loews - St.Louis

Best Western Plus St. Louis West-Westport

2.5 star property
19.8 km from Southhampton
8.0 out of 10, Very Good, (1027)
"The room was great and the bed was very comfortable "
United States
Joyce
The price is NT$3,100
NT$3,596 total
includes taxes & fees
Dec 7 - Dec 8
Best Western Plus St. Louis West-Westport

Sonesta ES Suites St. Louis - Chesterfield

3.0 star property
24.3 km from Southhampton
8.0 out of 10, Very Good, (1030)
"Clean room,Friendly staff, Good location and Good Breakfast options"
United States
Micheal
The price is NT$2,906
NT$3,371 total
includes taxes & fees
Dec 18 - Dec 19
Sonesta ES Suites St. Louis - Chesterfield

Pear Tree Inn St. Louis Arnold

2.5 star property
17.9 km from Southhampton
9.4 out of 10, Exceptional, (1000)
"The staff was very friendly and the rooms were very nice and clean"
United States
Connie
The price is NT$2,818
NT$3,258 total
includes taxes & fees
Dec 18 - Dec 19
Pear Tree Inn St. Louis Arnold

Courtyard by Marriott St. Louis Downtown/Convention Center

3.0 star property
Downtown St. Louis, 9.4 km from Southhampton
9.0 out of 10, Wonderful, (1017)
"Was a great stay. "
United States
Lorilyn
The price is NT$2,775
NT$3,301 total
includes taxes & fees
Jan 1 - 2026/1/2
Courtyard by Marriott St. Louis Downtown/Convention Center

Home2 Suites by Hilton St. Louis Downtown

3.0 star property
Downtown West, 9 km from Southhampton
8.0 out of 10, Very Good, (584)
"A convenient location downtown with great rooms and services."
United States
Paul
The price is NT$2,380
NT$2,783 total
includes taxes & fees
Dec 18 - Dec 19
Home2 Suites by Hilton St. Louis Downtown

Wingate by Wyndham St. Louis/Fenton Route 66

3.0 star property
16.7 km from Southhampton
7.8 out of 10, Good, (1101)
"The young lady that checked us in was very friendly and helpful."
United States
Wenona
The price is NT$2,476
NT$2,859 total
includes taxes & fees
Dec 18 - Dec 19
Wingate by Wyndham St. Louis/Fenton Route 66

Tru By Hilton St. Louis Downtown

2.5 star property
Downtown West, 9 km from Southhampton
7.6 out of 10, Good, (572)
"Everything great….very nice staff and security….delicious breakfast!!"
Canada
Derek
The price is NT$2,551
NT$2,983 total
includes taxes & fees
Jan 4 - 2026/1/5
Tru By Hilton St. Louis Downtown

AC Hotel by Marriott St. Louis Chesterfield

3.5 star property
26.1 km from Southhampton
9.2 out of 10, Wonderful, (233)
"Newer hotel, very clean, up to date and in nice area. "
United States
Johnny
The price is NT$3,727
NT$4,323 total
includes taxes & fees
Dec 21 - Dec 22
AC Hotel by Marriott St. Louis Chesterfield
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Southhampton

Find the best Southhampton areas and neighborhoods for the activities you enjoy most.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Top Southhampton Hotel Reviews

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Frequently asked questions

What is Southhampton like?
Travelers to the Southhampton neighborhood in St. Louis will be sure to enjoy their stay.
How many hotels will I find in the Southhampton area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 23 Southhampton hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Southhampton, will I receive a refund?
Yes! The majority of hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to view the best deals in Southhampton.
Where can I learn more about changing or cancelling my trip to Southhampton?
To find more details about rescheduling or cancelling your trip to Southhampton, click here.
What can I see and do in this St. Louis neighborhood?
A few places to visit in the area around Southhampton include Miniature Museum of Greater St. Louis, Lindenwood Park, and River des Peres Greenway Trailhead. When you're sightseeing in St. Louis, Tower Grove Tennis Center and George Washington Carver Garden are also worth a stop.