Find hotels in Panhandle, San Francisco
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Panhandle hotels
9.2 out of 10, Wonderful, (288)
"Great location, fun neighborhood!"
Madelyn
9.2 out of 10, Wonderful, (1005)
"Great hotel, convenient, clean, comfortable, quiet, great free breakfast and perfect price. Would definitely stay again!"
Allison
The price is NT$4,108
NT$5,059 total
includes taxes & fees
Jan 2 - 2026/1/3
9.0 out of 10, Wonderful, (1005)
"Clean room, great staff, convenient location "
Chia Wee
The price is NT$2,920
NT$3,437 total
includes taxes & fees
Jan 5 - 2026/1/6
8.6 out of 10, Excellent, (1005)
"Great hospitality staff is awesome will definitely stay here again !!"
Cindy
The price is NT$2,829
NT$3,325 total
includes taxes & fees
Dec 31 - 2026/1/1
8.8 out of 10, Excellent, (2020)
"Comfortable room, welcome glass of wine, easy shuttle to and from airport, friendly staff."
Carole
The price is NT$3,232
NT$4,634 total
includes taxes & fees
Jan 2 - 2026/1/3
La Quinta Inn & Suites by Wyndham San Francisco Airport West
La Quinta Inn & Suites by Wyndham San Francisco Airport West18.5 km from Panhandle
8.6 out of 10, Excellent, (1514)
"Clean room, decent breakfast. Close to airport. "
Karen
The price is NT$4,008
NT$4,607 total
includes taxes & fees
Jan 24 - 2026/1/25
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Panhandle
Find the best Panhandle areas and neighborhoods for the activities you enjoy most.
Union Square
Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.
Downtown San Francisco
Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.
Fisherman's Wharf
Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.
South of Market
From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.
Nob Hill
Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.
Frequently asked questions
Explore a world of travel with Expedia
- Fairmont Hotels in Haight-Ashbury
- Hotels near Bill Graham Civic Auditorium
- Boutique Hotels in Japantown
- Hotels near Hosfelt Gallery
- Hotels with Bars in Union Square
- 5 Star Hotels in Haight-Ashbury
- Hotels near Twin Peaks
- Hotels near Hyde St & Beach St Stop
- Hotels near Xanadu Gallery
- Romantic Hotels in San Francisco
- Four Seasons Hotels in Haight-Ashbury
- Hotels near San Francisco City Hall
- Best Western Hotels in San Francisco
- Hayes Valley Hotels
- Hotels near Moscone Convention Center
- Boutique Hotels in Downtown San Francisco
- Hotel Wedding Venues Hotels in Russian Hill
- Hotels near San Francisco Museum of Modern Art
- Hotels near Kite Hill Open Space
- 5 Star Hotels in Mission District
- Motels in San Francisco
- Hotels near Saint John Coltrane Church
- Civic Center Hotels
- Hotels near Mission Dolores Park
- Hotels with Free Parking in Nob Hill
- Hotels near Lafayette Park
- Hotels near Nobby Clarke Mansion
- Hotels near Presidio Golf Course
- Hotels near University of San Francisco
- 3 Star Hotels in Castro District
- Guest Houses in San Francisco
- Outer Sunset Hotels
- Hotels near Academy of Art University
- Sonesta Hotel in Haight-Ashbury
- Hotels near Kaiser Permanente Medical Center
- San Francisco Hotels
- Hotels near Full House House
- Historic Hotels in San Francisco
- Hostels in San Francisco
- Hotels near Yerba Buena Gardens
- Hostels in Irving St & 8th Ave Stop
- Boutique Hotels in Chinatown
- Hotels near Warfield Theatre
- Hotels near UCSF Medical Center
- Hotels with smoking rooms in San Francisco
- Hotels near War Memorial Opera House
- 5 Star Hotels in Castro District
- Hotels near Market St & Hyde St Stop
- Luxury Hotels in Downtown San Francisco
- Cheap Hotels in Union Square
- Hotels with Bars in Castro District
- Family Hotels in Civic Center
- Hyatt Hotels in Tenderloin
- Luxury Hotels in San Francisco
- Hotels near De Young Museum
- All-Inclusive Hotel Hotels in San Francisco
- Hotel Wedding Venues Hotels in Fisherman's Wharf
- Hotels near Wells Fargo History Museum
- Green Hotels in Castro District
- Hotels near UCSF/Chase Center Stop
- Visit Haight-Ashbury
- Warfield Theatre
- Swedenborgian Church
- Painted Ladies
- Visit Pacific Heights
- Visit Laurel Heights
- Kimball Natural History Museum
- Presidio of San Francisco
- Visit Tenderloin
- Oracle Park
- Neptune Society Columbarium
- Presidio Golf Course
- Visit Polk Gulch
- Conservatory of Flowers
- Grateful Dead House
- Visit Western Addition
- Moscone Convention Center
- San Francisco Zen Center
- Bill Graham Civic Auditorium
- California Academy of Sciences
- Haight Street
- Old St. Mary's Cathedral
- De Young Museum
- St. Patrick Catholic Church
- Visit South of Market
- Union Street
- Yerba Buena Ice Skating Center
- Steinhart Aquarium
- Car rentals near Union Square
- Avis Rental Cars in San Francisco
- Car rentals near Grateful Dead House
- Car rentals near Good Luck Parking Garage
- Rental cars San Francisco Intl. airport
- Car rentals near The Regency Ballroom
- Car rentals near Twin Peaks
- Hertz Rental Cars in Cow Hollow
- Hertz Rental Cars in Mission District
- Car rentals near Richmond District