Mission District 5 Stars Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Mission District 5 Star Hotels

Our top choices for Mission District 5-star hotels

Fairmont San Francisco

Fairmont San Francisco
5.0 star property
Downtown San Francisco
9.0 out of 10, Wonderful, (1,485 reviews)
"Great staff; nice restaurants. "
Canada
Robert
The price is NT$6,916
NT$9,647 total
includes taxes & fees
Mar 29 - Mar 30
Fairmont San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (1,004 reviews)
"Exelent location. Walcable srea easy access to bart"
United States
juan c
The price is NT$9,487
NT$11,166 total
includes taxes & fees
Apr 5 - Apr 6
Palace Hotel, a Luxury Collection Hotel, San Francisco

Taj Campton Place

Taj Campton Place
5.0 star property
Union Square
9.2 out of 10, Wonderful, (1,004 reviews)
"It was a perfect stay"
Canada
Travel To Explore
The price is NT$5,133
NT$7,149 total
includes taxes & fees
Mar 20 - Mar 21
Taj Campton Place

Four Seasons Hotel San Francisco at Embarcadero

Four Seasons Hotel San Francisco at Embarcadero
5.0 star property
Downtown San Francisco
9.6 out of 10, Exceptional, (1,004 reviews)
"Very friendly staff and overall had a great visit"
United States
Michael
The price is NT$14,760
NT$17,371 total
includes taxes & fees
Apr 17 - Apr 18
Four Seasons Hotel San Francisco at Embarcadero

1 Hotel San Francisco

1 Hotel San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (520 reviews)
"We loved our stay!"
United States
Michelle
The price is NT$13,746
NT$17,988 total
includes taxes & fees
Apr 5 - Apr 6
1 Hotel San Francisco

Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1,003 reviews)
" Excellent rooms and staff, terrific food, great location "
United States
Roberta
The price is NT$14,899
NT$17,535 total
includes taxes & fees
Apr 3 - Apr 4
Four Seasons Hotel San Francisco

Claremont Resort & Club

Claremont Resort & Club
5.0 star property
Claremont Hills
9.0 out of 10, Wonderful, (1,011 reviews)
"Great stay and property"
United States
Heather
The price is NT$7,852
NT$10,950 total
includes taxes & fees
Apr 4 - Apr 5
Claremont Resort & Club

The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1,002 reviews)
"Impeccable service, beautiful property, and great food and drinks in the lobby lounge."
United States
Michael
The price is NT$12,228
NT$15,938 total
includes taxes & fees
Mar 27 - Mar 28
The Ritz-Carlton, San Francisco

The St. Regis San Francisco

The St. Regis San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (713 reviews)
"The service was spectacular, enjoyed the restaurant as well as room service, and the room was very clean and spacious "
United States
Lauren
The price is NT$12,528
NT$16,206 total
includes taxes & fees
Apr 10 - Apr 11
The St. Regis San Francisco

Hotel Drisco

Hotel Drisco
5.0 star property
Pacific Heights
9.8 out of 10, Exceptional, (460 reviews)
"Great hotel and would highly recommend "
United States
Oliver
The price is NT$18,138
NT$21,097 total
includes taxes & fees
Apr 6 - Apr 7
Hotel Drisco

Fairmont Heritage Place, Ghirardelli Square

Fairmont Heritage Place, Ghirardelli Square
5.0 star property
Fisherman's Wharf
9.4 out of 10, Exceptional, (389 reviews)
"My family absolutely enjoyed our stay. Wonderful customer service and a great luxury room. Would definitely stay hear again!"
United States
Angel
The price is NT$23,678
NT$27,822 total
includes taxes & fees
Apr 9 - Apr 10
Fairmont Heritage Place, Ghirardelli Square

The Huntington Hotel

The Huntington Hotel
5.0 star property
Downtown San Francisco
The price is NT$25,582
NT$31,805 total
includes taxes & fees
Mar 29 - Mar 30
The Huntington Hotel

Neighbourgood Sutter Mansion

Neighbourgood Sutter Mansion
5.0 star property
Western Addition
9.4 out of 10, Exceptional, (237 reviews)
"Friendly staff, early 1900s decor and architecture."
United States
Louis
Neighbourgood Sutter Mansion

Dimond Abode Vacation Rental 3428

Dimond Abode Vacation Rental 3428
5.0 star property
Dimond
9.6 out of 10, Exceptional, (7 reviews)
"Cleanliness, amenities, staff. It was a really great stay."
United States
Phyllis
Dimond Abode Vacation Rental 3428
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mission District.
Still don't see what you're looking for?
See all properties in Mission District.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mission District Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Mission District?
Mansion on Sutter is among the most popular picks around the San Francisco neighborhood of Mission District based on reviews by Expedia customers. Four Seasons Hotel San Francisco and The St. Regis San Francisco are other 5-star hotels in this area that rank highest with travelers.
How much does it cost to stay in a 5-star hotel in Mission District?
There are a range of pricing options for a 5-star hotel in Mission District on Expedia. The amount you pay will depend on your vacation dates, length of your trip and other factors. Compare all of the available accommodations for your chosen dates and use our pricing and other filters to lock in the ideal luxury stay.

  • Search for the lowest price per night from NT$4,138

What makes a hotel 5 stars in Mission District?
From gourmet dining venues and 24-hour gyms to pools and the finest bedding, the 5-star experience in Mission District is all about indulgence and comfort. But it requires more than just upscale conveniences to earn a 5-star rating. Hotels must also deliver remarkable services like massage treatments, on-site laundry and 24/7 room service.

Explore a world of travel with Expedia