Mission District 5 Stars Hotels

Mansion on Sutter is among the most popular picks around the San Francisco neighborhood of Mission District based on reviews by Expedia customers. Four Seasons Hotel San Francisco and The St. Regis San Francisco are other 5-star hotels in this area that rank highest with travelers.

There are a range of pricing options for a 5-star hotel in Mission District on Expedia. The amount you pay will depend on your vacation dates, length of your trip and other factors. Compare all of the available accommodations for your chosen dates and use our pricing and other filters to lock in the ideal luxury stay.

• Search for the lowest price per night from NT$6,041

From gourmet dining venues and 24-hour gyms to pools and the finest bedding, the 5-star experience in Mission District is all about indulgence and comfort. But it requires more than just upscale conveniences to earn a 5-star rating. Hotels must also deliver remarkable services like massage treatments, on-site laundry and 24/7 room service.

Expedia's filter tool is the easiest way to search for exactly what you want. Select "5-star" and "All inclusive" to show the most luxurious resorts in Mission District where your lodging, meals, activities and entertainment are included in the upfront price. At these stays, your vacation is absolute indulgence from the moment you put down your suitcase.

Enjoy access to a variety of spa treatments and rejuvenating therapies at 1 Hotel San Francisco. Alternatively, prioritize your well-being and put yourself first at Fairmont San Francisco or Four Seasons Hotel San Francisco. These premium 5-star spa escapes are all located in or around Mission District.

Although there aren't any 5-star vacation rentals in Mission District on our site, we have a range of retreats that promise an awesome getaway. Discover one that suits your needs by checking out our vacation rentals in Mission District.