What is Southhampton like?

Travelers to the Southhampton neighborhood in St. Louis will be sure to enjoy their stay.

How many hotels will I find in the Southhampton area?

If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 23 Southhampton hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in Southhampton, will I receive a refund?

Yes! The majority of hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to view the best deals in Southhampton.

Where can I learn more about changing or cancelling my trip to Southhampton?

To find more details about rescheduling or cancelling your trip to Southhampton, click here .

What can I see and do in this St. Louis neighborhood?

A few places to visit in the area around Southhampton include Miniature Museum of Greater St. Louis, Lindenwood Park, and River des Peres Greenway Trailhead. When you're sightseeing in St. Louis, Tower Grove Tennis Center and George Washington Carver Garden are also worth a stop.

Find hotels in Southhampton, St. Louis

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Dates

March 2026

6

April 2026

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Our top choices for Southhampton hotels

Candlewood Suites St Louis St Charles by IHG

29.9 km from Southhampton

Ngozi

NT$3,207 total

includes taxes & fees

Mar 22 - Mar 23

Comfort Suites St Charles - St Louis

27.1 km from Southhampton

Jere

NT$3,175 total

includes taxes & fees

Mar 15 - Mar 16

Embassy Suites by Hilton St. Louis St. Charles

27.7 km from Southhampton

Jon Michael

NT$4,304 total

includes taxes & fees

Mar 15 - Mar 16

Ameristar Casino Resort and Spa

26.6 km from Southhampton

Wanda

NT$6,831 total

includes taxes & fees

Mar 9 - Mar 10

Country Inn & Suites by Radisson, St. Charles Historic District

27 km from Southhampton

Chad

NT$4,151 total

includes taxes & fees

Apr 5 - Apr 6

Courtyard by Marriott St Louis Creve Coeur

Creve Coeur, 16.7 km from Southhampton

Heather

NT$4,387 total

includes taxes & fees

Apr 3 - Apr 4

Best Western St. Louis-Kirkwood Route 66

10.9 km from Southhampton

Xiongyu

NT$3,488 total

includes taxes & fees

Mar 8 - Mar 9

Drury Inn & Suites St. Louis Union Station

Downtown West, 7.9 km from Southhampton

Alexandra

NT$5,128 total

includes taxes & fees

Mar 15 - Mar 16

Motel 6 Hazelwood, MO

22.6 km from Southhampton

Jaziel

NT$2,240 total

includes taxes & fees

Mar 9 - Mar 10

Fairfield Inn & Suites by Marriott St. Louis Downtown

Downtown West, 7.9 km from Southhampton

Elizabeth

NT$4,198 total

includes taxes & fees

Apr 6 - Apr 7

Home2 Suites by Hilton St. Louis Downtown

Downtown West, 9 km from Southhampton

Catherine

NT$3,618 total

includes taxes & fees

Mar 16 - Mar 17

Courtyard by Marriott St. Louis Downtown/Convention Center

Downtown St. Louis, 9.4 km from Southhampton

Emily

NT$3,815 total

includes taxes & fees

Mar 22 - Mar 23

Embassy Suites by Hilton St. Louis Downtown

Downtown St. Louis, 9.5 km from Southhampton

Kevin

NT$4,299 total

includes taxes & fees

Mar 15 - Mar 16

Missouri Athletic Club

Downtown St. Louis, 9.7 km from Southhampton

Annette

NT$6,451 total

includes taxes & fees

Mar 10 - Mar 11

Pear Tree Inn St. Louis Airport

18.4 km from Southhampton

Brandy

NT$3,360 total

includes taxes & fees

Mar 15 - Mar 16

Outdoor pool, open 8:00 AM to 8:30 PM, pool umbrellas, sun loungers

Le Méridien St. Louis Clayton

8 km from Southhampton

Hannah

NT$5,048 total

includes taxes & fees

Mar 15 - Mar 16

Holiday Inn St. Louis - Creve Coeur by IHG

17.5 km from Southhampton

Jennifer

NT$4,064 total

includes taxes & fees

Apr 2 - Apr 3

Courtyard by Marriott St. Louis Downtown West

Downtown West, 7.7 km from Southhampton

Ashley

NT$4,301 total

includes taxes & fees

Mar 29 - Mar 30

Hampton Inn By Hilton St Louis Airport

17.8 km from Southhampton

Allyn

NT$5,120 total

includes taxes & fees

Mar 15 - Mar 16

Fairfield Inn & Suites St Louis Westport

18.5 km from Southhampton

Jim

NT$4,499 total

includes taxes & fees

Apr 5 - Apr 6

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Where to stay in Southhampton

Find the best Southhampton areas and neighborhoods for the activities you enjoy most.

Gateway Arch featuring a monument, night scenes and a park

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

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Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

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Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

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Anheuser-Busch Brewery featuring heritage architecture and a garden

Soulard

You'll enjoy the bars and churches in Soulard. You might want to make time for a stop at Anheuser-Busch Brewery or Soulard Farmer's Market.

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Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

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