Southeast Minnesota Vacations

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Where to stay in Southeast Minnesota

Find the best Southeast Minnesota areas and neighborhoods for the activities you enjoy most. Learn more about Southeast Minnesota
Rochester showing skyline and a city

Downtown Rochester

2 out of top 10 points of interest in this area
4.5/5(250 area reviews)

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Art Center are top sights worth seeing.

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Find the Best Southeast Minnesota Vacation Packages

Southeast Minnesota Hotel Deals

Kahler Grand Hotel
Kahler Grand Hotel
3 out of 5
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
8.2/10 Very Good! (1,426 reviews)
"I had spent the 2 nights there in 2 different rooms. One room the thermostat was set on 50 the other was set on 60. Both rooms did not achieve anything close to the set temperature, it was more like 72 by the thermostat and gained temperature the further a way you got. Also, there was no fan option ..."

Reviewed on 2025/7/1

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Kahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
3.5 out of 5
9 3rd Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
7.8/10 Good! (1,369 reviews)
"Staff were very courteous. Continental breakfast was very nice. Rooms were very comfortable and large enough. Lounge area with pool' pool table and snacks was very welcoming. Breakfast nook was great."

Reviewed on 2025/6/29

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Kahler Inn and Suites - Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3 out of 5
110 Civic Center Drive NW, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is NT$3,887 per night from Jul 4 to Jul 5
NT$3,887
NT$4,474 total
Jul 4 - Jul 5
includes taxes & fees
9/10 Wonderful! (952 reviews)
"Beth was very kind at check-in and bar service. Beautiful facility."

Reviewed on 2025/6/30

Hyatt House Rochester/Mayo Clinic Area
See all 909 properties in Southeast Minnesota
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Southeast Minnesota vacation package cost?
Our Southeast Minnesota vacation packages, which start from as low as , are an ideal way to save. Select your favorite flights, hotels and rental cars to create a personalized itinerary.
How do I get a cheap travel package to Southeast Minnesota?
Bundle your flights and hotels with Expedia to save on your next exciting adventure. With more than 550 partner airlines and 1,000,000 properties across the globe, your Southeast Minnesota vacation package can be tailored exactly to suit your travel style. With all those extra dollars, why not add a few interesting activities and tours? It's an easy way to unlock even more discounts. The vacation you've always dreamed of in Southeast Minnesota is much closer than you thought!
What are the top hotels in Southeast Minnesota?
For hotels in Rochester with comfy beds and friendly service, you can't go past Kahler Inn and Suites - Mayo Clinic Area and Kahler Grand Hotel. If you plan to visit Lake City as well, you'll get a great night's sleep at Pet - Friendly Wabasha Studio: Boat or Peaceful Condo In Wabasha With Beautiful River Bluff Location - Lower Unit.
How far in advance should I book my Southeast Minnesota vacation?
Travelers are usually able to browse international airfares on Expedia within 12 months of the departure date. Booking last minute? With a little bit of luck, it's still possible to score an affordable ticket only weeks before your flight.
What does an Expedia Southeast Minnesota travel package include?
It's up to you! You can select from a range of Southeast Minnesota bundles, such as a flight, hotel and rental car. You can also book a hotel with a flight, or a rental car with a flight. Once you've made your booking, you can add the fun stuff like activities and experiences. Whatever your perfect Southeast Minnesota getaway looks like, you'll save!
What should I know before booking a Southeast Minnesota travel package?
Our prices are always low. However, you'll grab even more savings if you book your flights, hotels and car rentals together. With an Expedia travel package, you'll always get transparent pricing and lots of choice.
Can I choose my airline with a Southeast Minnesota Expedia vacation package?
Yes, you sure can. We have more than 550 partner airlines across the globe, so pick the carrier that fits your travel needs.
If I'm not able to travel, can I cancel my Southeast Minnesota vacation package?
It's impossible to predict what the future holds, so it's comforting to know that you can cancel or change your Southeast Minnesota vacation package. If your booking was made in the last 24 hours, you may be entitled to a refund. If it's an older booking, your hotel, airline or car rental company may charge a fee. Visit our Customer Service Portal for further details.

Discover the most popular places to visit in Southeast Minnesota

Guided tours are offered at Mystery Cave where we came upon this little body of water down in the cave. It was very cool!! The water was so clear and beautiful!! #InStone

Forestville Mystery Cave State Park

4.5/5(10 reviews)

Commune with nature and explore the great outdoors at Forestville Mystery Cave State Park during your travels in Preston. Wander the parks or discover the area's countryside.

Forestville Mystery Cave State Park
Winona State University

Winona State University

4.5/5(94 reviews)

Enjoy the collegiate vibe when you visit Winona State University, during your trip to Winona. Stroll along the riverfront or experience the area's museums.

Winona State University

Mayo Clinic Hospital - Saint Marys Campus

4.5/5(391 reviews)

Though Mayo Clinic Hospital - Saint Marys Campus might be what brings you to town, perhaps you'll have a chance to explore more of Rochester while you are here.

Mayo Clinic Hospital - Saint Marys Campus
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.