Find hotels in Santo Domingo, Mexico City from NT$1,072

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Discover 6,113 Santo Domingo hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Zocalo Central & Rooftop Mexico City

4.0 star property
Historic Center, 12.2 km from Santo Domingo
9.8 out of 10, Exceptional, (2603)
"Great place to stay"
United States
Luke
The price is NT$3,827
NT$4,573 total
includes taxes & fees
Nov 30 - Dec 1
Zocalo Central & Rooftop Mexico City

Hotel Catedral

4.0 star property
Historic Center, 12.4 km from Santo Domingo
9.4 out of 10, Exceptional, (2549)
"Room was spotless, breakfast was excellent and hotel staff were welcoming "
United States
Olga
The price is NT$5,710
NT$6,824 total
includes taxes & fees
Nov 22 - Nov 23
Hotel Catedral

Hotel Bellas Artes

4.0 star property
Historic Center, 12.1 km from Santo Domingo
9.8 out of 10, Exceptional, (492)
"Loved this hotel from the location to how nice, modern and clean it was plus staff was amazing. Definitely booking here again!"
United States
Danika
The price is NT$2,743
NT$3,278 total
includes taxes & fees
Nov 25 - Nov 26
Hotel Bellas Artes

Hotel Parque Satelite

3.0 star property
22.4 km from Santo Domingo
9.0 out of 10, Wonderful, (1004)
"Good place to stay nice and clean"
United States
guillermo
The price is NT$1,493
NT$1,791 total
includes taxes & fees
Nov 26 - Nov 27
Hotel Parque Satelite

Hilton Mexico City Reforma

4.5 star property
Reforma, 12 km from Santo Domingo
9.4 out of 10, Exceptional, (1047)
"great place . friendly staff and everything was to perfection."
United States
Adriana
The price is NT$5,543
NT$6,624 total
includes taxes & fees
Dec 16 - Dec 17
Hilton Mexico City Reforma

Hotel Juarez

2.5 star property
Historic Center, 12.2 km from Santo Domingo
9.0 out of 10, Wonderful, (1764)
"Very good tourist place. "
United States
Guillermina
The price is NT$897
NT$1,072 total
includes taxes & fees
Nov 30 - Dec 1
Hotel Juarez

Sleep Inn Ciudad de México

3.0 star property
12.3 km from Santo Domingo
8.2 out of 10, Very Good, (982)
"Nice hotel. "
United States
Alejandra
The price is NT$2,147
NT$2,566 total
includes taxes & fees
Dec 1 - Dec 2
Sleep Inn Ciudad de México

Historico Central Hotel

4.0 star property
Historic Center, 12 km from Santo Domingo
9.8 out of 10, Exceptional, (2387)
"Location was great and hotel was clean and comfortable "
United States
Daniela
The price is NT$3,599
NT$4,301 total
includes taxes & fees
Nov 30 - Dec 1
Historico Central Hotel

Royal Pedregal Hotel

4.0 star property
Tlalpan, 4.6 km from Santo Domingo
9.0 out of 10, Wonderful, (1771)
"Excellent option if you need to be in the southern part of CDMX"
United States
Carlos
Royal Pedregal Hotel

Hotel Punto MX

3.5 star property
Historic Center, 11.7 km from Santo Domingo
9.0 out of 10, Wonderful, (1399)
"Everything was perfect! Room , location, "
United States
Yohena
The price is NT$1,661
NT$1,985 total
includes taxes & fees
Dec 8 - Dec 9
Hotel Punto MX

Holiday Inn Express Mexico Basilica by IHG

3.0 star property
14.7 km from Santo Domingo
9.2 out of 10, Wonderful, (1026)
"Excellent stay!"
United States
Derek
The price is NT$2,009
NT$2,401 total
includes taxes & fees
Dec 2 - Dec 3
Holiday Inn Express Mexico Basilica by IHG

Camino Real Santa Fe

5.0 star property
Santa Fe, 11 km from Santo Domingo
9.0 out of 10, Wonderful, (2657)
"Great place to stay "
United States
KARLA
The price is NT$2,586
NT$3,090 total
includes taxes & fees
Nov 29 - Nov 30
Camino Real Santa Fe

Fiesta Americana México Toreo

4.0 star property
15 km from Santo Domingo
9.6 out of 10, Exceptional, (1002)
"It was a wonderful stay"
United States
Lukas
The price is NT$5,460
NT$6,552 total
includes taxes & fees
Nov 30 - Dec 1
Fiesta Americana México Toreo

Punta Alameda

2.0 star property
Downtown Mexico City, 11.6 km from Santo Domingo
9.4 out of 10, Exceptional, (160)
"Regular cleaning, friendly staff"
Canada
Mukul
Punta Alameda

Hampton Inn & Suites Mexico City - Centro Historico

3.0 star property
Historic Center, 11.7 km from Santo Domingo
9.0 out of 10, Wonderful, (1061)
"Felt safe and was walking distance to stores and food "
United States
MARIA
The price is NT$2,723
NT$3,254 total
includes taxes & fees
Dec 2 - Dec 3
Hampton Inn & Suites Mexico City - Centro Historico

Hotel Brasilia

3.0 star property
16.5 km from Santo Domingo
9.0 out of 10, Wonderful, (1003)
"Super clean hotel and the staff very pleasant and friendly."
United States
Emanuel
The price is NT$1,853
NT$2,215 total
includes taxes & fees
Dec 7 - Dec 8
Hotel Brasilia

Hotel Plaza Revolución

3.5 star property
12.1 km from Santo Domingo
8.8 out of 10, Excellent, (1004)
"Really nice hotel. Very clean, in a nice area. The staff is super friendly and nice. "
United States
Inna
Hotel Plaza Revolución

Fiesta Inn Insurgentes Sur

3.5 star property
4.4 km from Santo Domingo
9.2 out of 10, Wonderful, (1016)
"Excellent hotel. "
United States
Annie
The price is NT$3,495
NT$4,176 total
includes taxes & fees
Nov 30 - Dec 1
Fiesta Inn Insurgentes Sur

Krystal Grand Suites Insurgentes

4.0 star property
3.4 km from Santo Domingo
9.0 out of 10, Wonderful, (1304)
"Excellent location"
United States
Jorge
The price is NT$3,214
NT$3,840 total
includes taxes & fees
Dec 12 - Dec 13
Krystal Grand Suites Insurgentes

Hotel MX zocalo CDMX, Trademark Collection by Wyndham

3.5 star property
Historic Center, 12.1 km from Santo Domingo
8.4 out of 10, Very Good, (634)
"Clean room excellent staff and nearby everywhere "
United States
PATRICIA
The price is NT$1,482
NT$1,772 total
includes taxes & fees
Dec 3 - Dec 4
Hotel MX zocalo CDMX, Trademark Collection by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Domingo

Find the best Santo Domingo areas and neighborhoods for the activities you enjoy most.

Polanco

Luxury shopping along Presidente Masaryk Avenue and upscale restaurants await, while nearby Chapultepec Park houses the National Museum of Anthropology and other cultural institutions. Enjoy a stroll in Parque Lincoln or explore Polanquito's vibrant dining scene.

Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like MUCA Roma and Centro Cultural El Punto, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

La Condesa

Fashionable and popular with young professionals, Condesa boasts international restaurants, bars, and nightclubs. Stroll along tree-lined avenues, admire Art Deco architecture, and visit landmarks like Edificio San Martín and Basurto Building.

Historic Center

Historic center with 1,550 significant buildings, the neighborhood offers museums like MUNAL and Palacio de Bellas Artes. Enjoy upscale eateries, fashionable stores, and pedestrianized streets for easy exploration.

Reforma

Consider a visit to Angel of Independence Monument and take some time to enjoy the important monuments during your time in Reforma. If you want to see more of the city, jump on the metro at Insurgentes Station or Cuauhtemoc Station.

Top Santo Domingo Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What is Santo Domingo like?
Travelers to Mexico City's Santo Domingo neighborhood will be sure to enjoy a stay in this neighborhood.
How many hotels should I expect to find in the Santo Domingo area?
Book one of Expedia's 5 hotels and other accommodations in Santo Domingo and start exploring everything Mexico City has to offer.
If I need to cancel my hotel reservation in Santo Domingo, will I receive a refund?
Yes, most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best deals in Santo Domingo.
Where can I learn more about changing or cancelling my trip to Santo Domingo?
For additional details about updating your trip to Santo Domingo or cancelling it, click here.
What are the top things to see and do in Santo Domingo?
Parroquia de San Juan Bautista, Casa del Teatro, and Museo Diego Rivera Anahuacalli are just a few of the places to visit in and around Santo Domingo. While you're out sightseeing, Museo de la Ciudad and Hidalgo Plaza are a couple of additional sights to visit in Mexico City.