Santo Domingo Vacations

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Where to stay in Santo Domingo

Find the best Santo Domingo areas and neighborhoods for the activities you enjoy most. Learn more about Santo Domingo
The Cibeles fountain in Mexico City is an exact replica of the Cibeles fountain that is located in the Plaza de Cibeles in Madrid, Spain

Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

Find hotels in Roma Norte

Santo Domingo Hotel Deals

Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico

4 out of 5
Mexico City
Fully refundable
The price is NT$3,802 per night from Feb 25 to Feb 26
NT$3,802
NT$4,543 total
Feb 25 - Feb 26
includes taxes & fees
8.6/10 Excellent! (12,146 reviews)
I always stay at this establishment when I am called for work in the area of the airport. My one compliant is that everytime I book a room it's always more expensive than the time before. At this rate I may unfortunately be forced to look elsewhere 😓.

Reviewed on 2026/2/3

Camino Real Aeropuerto Mexico
ULIV Mexico City

ULIV Mexico City

4.5 out of 5
235 Av. Insurgentes Sur Roma Norte Mexico City CDMX
The price is NT$4,866 per night from Feb 15 to Feb 16
NT$4,866
NT$5,815 total
Feb 15 - Feb 16
includes taxes & fees
8.8/10 Excellent! (1,218 reviews)
Room was great staff awesome

Reviewed on 2026/2/2

ULIV Mexico City
Historico Central Hotel

Historico Central Hotel

4 out of 5
Simón Bolívar No. 28 Mexico City Mexico City
Fully refundableReserve now, pay when you stay
The price is NT$4,545 per night from Feb 24 to Feb 25
NT$4,545
NT$5,432 total
Feb 24 - Feb 25
includes taxes & fees
9.8/10 Exceptional! (2,385 reviews)
Lovely hotel with great staff, we couldn’t believe everything was included in the price (coffee shop food and drinks, mini bar, breakfast) great location for central historic area. A bit more hectic than Roma Norte where we stayed before but stunning buildings and good for shopping

Reviewed on 2026/2/4

Historico Central Hotel
See all 5,841 properties in Santo Domingo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santo Domingo vacation package cost?
We make it simple to see the world, with Santo Domingo packages starting from as low as . You'll have the flexibility to bundle your preferred airlines, hotels and car rental. For the ultimate getaway, why not add some activities and tours to your travel itinerary?
How do I get a cheap travel package to Santo Domingo?
Book everything all in one place with our Santo Domingo vacation packages. You'll discover deals on hotels, flights and more that'll keep your wallet happy and your spirit of adventure alive. And, with more than 550 partner airlines and 1,000,000 properties globally to choose from, there are endless opportunities to mix and match as you want.
Where should I stay in Santo Domingo?
Urban explorers come from every corner of the globe to see Basilica of Our Lady of Guadalupe and Zócalo in Santo Domingo. Book a hotel close to these top attractions and visit them at your leisure.
How far in advance should I book my Santo Domingo vacation?
It depends on the airline, but you can generally browse through international flights on Expedia nearly a year in advance. While it's generally recommended to book ahead of time, lucky travelers will sometimes find a cheaper ticket only weeks before the date of departure.
What does an Expedia Santo Domingo travel package include?
With Expedia, you can select a combination of hotels, car rentals and flights to build your ideal Santo Domingo package. Once you've made your booking, you can add on all the fun stuff like sightseeing tours and activities. Don't forget — the more you bundle, the more discounts you'll get!
What should I know before booking a Santo Domingo travel package?
When you book your hotels, flights and car rentals together, you'll enjoy amazing discounts. Whether you're planning a beach escape in a villa or want to stay in a comfortable hotel in the city, Expedia will help make it happen.
Can I choose my airline with a Santo Domingo Expedia vacation package?
Expedia has access to more than 550 airline partners globally, so you sure can! Just choose the carrier you want and craft your ideal Santo Domingo getaway.
If I'm not able to travel, can I cancel my Santo Domingo vacation package?
Don't stress if you're rethinking your Santo Domingo vacation package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur charges from your hotel, airline or car rental company. We totally understand your circumstances can suddenly change, so make your way to our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.

Discover the most popular places to visit in Santo Domingo

The Angel of Independence Monument showing a monument, heritage elements and city views

Angel of Independence Monument

Gaze upon this tall and majestic structure that symbolizes for the whole nation’s citizens the country’s long struggle for independence.

Angel of Independence Monument
Zócalo featuring heritage architecture, a city and night scenes

Zócalo

This is the heart of Mexico City with wide-ranging architecture, cultural events and a lively arts scene.

Zócalo
Reforma which includes a high rise building, a park and a city

Paseo de la Reforma

Like the Champs Elysées in Paris, this famous wide avenue provides a distinctive elegance to the historic plan of this huge global city.

Paseo de la Reforma
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.