Find Resorts & Hotels with Spas in Mission District, CA

Check availability on Mission District Resorts & Hotels with Spas

Our top choices for Mission District hotels with a spa

Hot tub, body treatments, aromatherapy, hot stone massages

Cavallo Point

Cavallo Point
4.5 star property
Sausalito
9.2 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Tranquil escape at this historic bayside sanctuary with deep-tissue massages and aromatherapy in 11 serene treatment rooms.
Cavallo Point
Indoor pool

The Huntington Hotel

The Huntington Hotel
5.0 star property
Downtown San Francisco
9.6 out of 10, Exceptional, (4 reviews)
The Huntington Hotel
Property amenity

1 Hotel San Francisco

1 Hotel San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (528 reviews)
  • cleanliness
    Rejuvenate at this remodeled luxury hotel with Bamford Wellness Spa's outdoor treatments and garden sanctuary.
1 Hotel San Francisco
City view

Argonaut Hotel

Argonaut Hotel
4.5 star property
Fisherman's Wharf
9.4 out of 10, Exceptional, (1,288 reviews)
  • cleanliness
    Historic bayfront hotel offers indulgent spa massages and wellness amenities in scenic national park setting.
Argonaut Hotel
Steam room, aromatherapy, hot stone massages, deep-tissue massages

Casa Madrona Hotel & Spa

Casa Madrona Hotel & Spa
4.0 star property
Downtown
9.2 out of 10, Wonderful, (1,003 reviews)
  • cleanliness
    Experience spa luxury at this bayside hotel with 4 treatment rooms, steam room, and customized massages overlooking scenic bay views.
Casa Madrona Hotel & Spa
Reception

The Beach House Hotel Half Moon Bay

The Beach House Hotel Half Moon Bay
3.5 star property
El Granada
9.4 out of 10, Exceptional, (1,003 reviews)
  • cleanliness
    Rejuvenate with oceanfront spa treatments, bay views, and private fireplaces at this coastal sanctuary perfect for relaxation retreats.
The Beach House Hotel Half Moon Bay
Couples treatment rooms, deep-tissue massages, Swedish massages, facials

Claremont Resort & Club

Claremont Resort & Club
5.0 star property
Claremont Hills
9.0 out of 10, Wonderful, (1,011 reviews)
  • cleanliness
    Escape to a regional park oasis with 32 spa treatment rooms, 3 outdoor pools, and outdoor tennis courts for the ultimate wellness retreat.
Claremont Resort & Club
Reception

Oceano Hotel and Spa

Oceano Hotel and Spa
4.0 star property
El Granada
9.4 out of 10, Exceptional, (1,002 reviews)
  • cleanliness
    Experience seaside wellness with cozy fireplaces and couples spa treatments at this tranquil oceanfront retreat.
Oceano Hotel and Spa
Exterior

Kimpton Alton Fisherman's Wharf by IHG

Kimpton Alton Fisherman's Wharf by IHG
4.5 star property
Fisherman's Wharf
9.2 out of 10, Wonderful, (1,512 reviews)
  • cleanliness
    Revitalize with facials and deep-tissue massages at this luxury hotel offering a 24-hour gym and rooftop garden near Ghirardelli Square.
Kimpton Alton Fisherman's Wharf by IHG
Terrace/patio

Fairmont San Francisco

Fairmont San Francisco
5.0 star property
Downtown San Francisco
9.0 out of 10, Wonderful, (1,506 reviews)
  • cleanliness
    Pamper yourself with rejuvenating spa treatments and historical elegance at this centrally located San Francisco retreat with bay views.
Fairmont San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Choose what matters most at spa hotels in Mission District

Pool
Breakfast included

Top Mission District Hotel Reviews

Handlery Union Square Hotel

Handlery Union Square Hotel

10/10 Excellent
"Nice hotel and great location at union square"
Anthony 4-night trip
Posted 1 hour ago
Handlery Union Square Hotel

Explore a world of travel with Expedia

Frequently asked questions

Looking to vacation at a spa hotel in Mission District?
Book one of our wonderful spa hotels and treat yourself from the moment you arrive. Check out the art galleries and bars in Mission District—your day trip starts here. Be sure to pay a visit to the museums during your stay. Spa hotels are the perfect way to break away from your routine and add a layer of luxury to your vacation.
What's there to see and do in Mission District?
Experience Mission District with a stop at SOMA Pilipinas, San Francisco Public Library, and SF Armory. If you have a little extra time during your trip, you might want to make a stop at Mission San Francisco de Asís and Paxton Gate.
What is a Mission District spa hotel?
Spa hotels in Mission District provide lodging and have an on-site spa which offers services such as massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.