The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

louis

NT$3,195

NT$3,641 total

includes taxes & fees

Nov 22 - Nov 23

A cluster of modern, multi-story buildings with a river in the foreground.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

A golf course with a pond, a clubhouse, and a hilly backdrop.

A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Stephanie

NT$4,168

NT$4,758 total

includes taxes & fees

Oct 28 - Oct 29

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

A modern hotel lobby with a central bar area, seating arrangements, and a clean, contemporary design.

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

3. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

LAURA

NT$3,550

NT$4,048 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor patio with two sofas facing a stone fire pit, under a pergola with string lights.

A modern lobby with a seating area, a kitchen, and a reception desk.

A multi-story hotel with a prominent entrance, large windows, and a well-lit facade.

A modern living room with a sectional sofa, orange ottomans, a dining area, and a kitchen with a stone accent wall.

4. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Claudia

NT$4,545

NT$5,193 total

includes taxes & fees

Nov 22 - Nov 23

A modern hotel with a brick facade, large windows, and a covered entrance area.

A modern bar area with a wooden ceiling, bar stools, and a counter with a digital screen.

A hotel room with a desk, two beds, a TV, and a large window.

A modern lobby with a sectional sofa, a round coffee table, and a mural on the wall.

5. Springhill Suites Phoenix Scottsdale Marriott

18.2 km from Mayo Clinic Scottsdale

Lucinda

NT$3,569

NT$4,068 total

includes taxes & fees

Nov 22 - Nov 23

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

6. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Joseph

NT$2,882

NT$3,285 total

includes taxes & fees

Oct 26 - Oct 27

A spacious living area with a kitchen, modern furniture, and a fireplace.

A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.

A spacious lobby with a high ceiling, modern chandeliers, a fire feature, and a large TV screen.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

7. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

NT$3,880

NT$4,429 total

includes taxes & fees

Oct 26 - Oct 27

A hotel room with two beds, a desk, a lamp, and artwork on the wall.

A hotel entrance with a sign reading 'spark by Hilton' and a covered outdoor area with palm trees.

A modern hotel room with a large window, a desk with a lamp, a chair, and a television.

A modern office space with multiple desks, chairs, and a meeting area.

8. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Herbert M Beatty

NT$2,647

NT$3,022 total

includes taxes & fees

Nov 3 - Nov 4

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

A spacious living area with a sofa, chairs, a coffee table, and a TV mounted on the wall.

A reception area with marble reception desks, a wooden ceiling, and a wall-mounted refrigerator.

A bar area with a long counter, multiple stools, and overhead pendant lighting.

9. Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Deborah

NT$4,401

NT$5,016 total

includes taxes & fees

Nov 15 - Nov 16

A modern infinity pool with a view of mountains and a sunset.

A restaurant with high tables and booths, floral wall decorations, and a view of the mountains.

A poolside lounge with a view of a hotel building, a TV, and a bar area with a bottle of champagne.

A modern bar area with a unique ceiling design, a bar counter with multiple screens, and a patterned carpet.

10. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Jessica

NT$5,194

NT$6,851 total

includes taxes & fees

Nov 22 - Nov 23

A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.

A modern lobby with a brick wall, seating area, and a flat-screen TV.

A modern hotel with a covered entrance, multiple floors, and a parking lot.

A hotel room with two beds, a TV, a desk, a chair, and a view of palm trees.

11. Hyatt Place Phoenix/Mesa

17.8 km from Mayo Clinic Scottsdale

Laura

NT$4,401

NT$5,029 total

includes taxes & fees

Nov 22 - Nov 23

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.

A bar area with a bar counter, multiple chairs, and a sofa.

A restaurant setting with round tables, chairs, and empty wine glasses.

12. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

Marie

NT$3,335

NT$3,801 total

includes taxes & fees

Oct 26 - Oct 27

A landscaped garden with a fountain, palm trees, and a building with a red roof.

A modern kitchen with a glass dining table, bar stools, and a built-in island with a microwave and oven.

A tranquil pond with a fountain, surrounded by lush greenery and a large building in the background.

A pool area with a rock formation, palm trees, and lounge chairs.

13. Westgate Painted Mountain Golf Resort

17.4 km from Mayo Clinic Scottsdale

Curtis

NT$3,270

NT$3,737 total

includes taxes & fees

Nov 8 - Nov 9

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A spacious lobby with a stone wall, a fireplace, and a seating area with a sofa and chairs.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

A swimming pool with people on inflatable floats, lounge chairs, and umbrellas in the background.

14. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Linda

NT$3,793

NT$5,299 total

includes taxes & fees

Oct 26 - Oct 27

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.

15. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Colleen

NT$3,713

NT$4,234 total

includes taxes & fees

Nov 8 - Nov 9

A hotel dining area with a table and chairs, patterned curtains, and a view through large windows.

A hotel room with a large window, a desk, a bed, a TV, and a chair.

A hotel lobby with a bar area, seating, and a reception desk.

A building entrance with a stone facade, large glass doors, and potted plants.

16. Hampton Inn & Suites Scottsdale at Talking Stick

9.1 km from Mayo Clinic Scottsdale

Cynthia

NT$3,852

NT$4,392 total

includes taxes & fees

Nov 22 - Nov 23

A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and a television screen.

An outdoor seating area with a fire feature, surrounded by a fence and palm trees, under a sunset sky.

A bar area with multiple seating options, a bar counter, and a television screen displaying sports.

A spacious hotel lobby with a reception desk, seating areas, and a view of the dining and kitchen areas.

17. Embassy Suites by Hilton Phoenix Scottsdale

17.8 km from Mayo Clinic Scottsdale

Matthew

NT$4,785

NT$5,411 total

includes taxes & fees

Nov 22 - Nov 23

A hotel with a modern design, featuring a curved roof, large windows, and a landscaped entrance area with palm trees and shrubs.

A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.

A swimming pool with lounge chairs and umbrellas, surrounded by a fence and palm trees.

A buffet with labeled trays of turkey sausage and cookies.

18. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Melanie

NT$3,195

NT$3,641 total

includes taxes & fees

Nov 23 - Nov 24

A resort with multiple buildings, a large pool area, and surrounding mountains.

An outdoor wedding reception with round tables set with white chairs, floral centerpieces, and a view of the city in the background.

A dining area with a table set for six, overlooking a scenic landscape.

A dining area with a table and chairs, a view of a cityscape, and decorative wall panels.

19. ADERO Scottsdale Resort, Autograph Collection

3.6 km from Mayo Clinic Scottsdale

Garrett

NT$6,814

NT$9,082 total

includes taxes & fees

Oct 31 - Nov 1

A swimming pool with a bridge structure, surrounded by buildings with outdoor seating and a clear sky.

A breakfast bar with a variety of baked goods and a sign indicating fresh baked items.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.

A reception area with a blue counter, a television screen, and a modern interior design.

20. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Ally Marie

NT$4,140

NT$4,719 total

includes taxes & fees

Nov 22 - Nov 23

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very good 1,093 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,035 reviews	View
Comfort Suites Scottsdale Talking Stick Entertainment District	9.2 Wonderful 2,057 reviews	View
Home2 Suites by Hilton Mesa Longbow, AZ	9.6 Exceptional 921 reviews	View
Springhill Suites Phoenix Scottsdale Marriott	9.4 Exceptional 456 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Staybridge Suites Scottsdale - Talking Stick by IHG

10/10 Excellent

"Very convenient and enjoyable location"

Sonesta Select Scottsdale at Mayo Clinic Campus

10/10 Excellent

"Location is wonderful for appointments I have with Mayo Clinic or hospital"

Comfort Suites Scottsdale Talking Stick Entertainment District

10/10 Excellent

"Staff great Reasonable rates and location was perfect."

ADERO Scottsdale Resort, Autograph Collection

10/10 Excellent

"We had a great weekend at Adero, a lovely location that is in the foothills and very quiet. We had a beautiful view from our room and enjoyed playing tennis both days. The staff was really helpful and friendly. We would definitely recommend!"

Inn at Eagle Mountain

8/10 Good

"I think I was able to get one of the last rooms same day....beautiful room, comfortable and spacious, bathroom as well. My view was the parking lot, but next time I will book in advance for hopefully a valley view. Friendly young front desk rep offering wine tasting at that time."

Aiden by Best Western Scottsdale North

8/10 Good

"Room was not done at check in"

Sonesta Simply Suites Phoenix Scottsdale

10/10 Excellent

"Great price! It was actually a suitet with a kitchenette although I didn't use it. I would definitely stay there again if I was in the area!"

Fountain Park Hotel, BW Signature Collection

10/10 Excellent

"Everything was in order. No issues, helpful staff and a good location"

Wekopa Casino Resort

10/10 Excellent

"We had fun at the slot machines over the Fri-Sat weekend. Hotel is clean and decent. They had healthy options at the fast food. We'll be back."

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$3,022

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. Comfort Suites Scottsdale Talking Stick Entertainment District

4. Home2 Suites by Hilton Mesa Longbow, AZ

5. Springhill Suites Phoenix Scottsdale Marriott

6. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

7. Fountain Park Hotel, BW Signature Collection

8. Spark by Hilton Fountain Hills Scottsdale

9. Hyatt House North Scottsdale

10. Talking Stick Resort

11. Hyatt Place Phoenix/Mesa

12. Aiden by Best Western Scottsdale North

13. Westgate Painted Mountain Golf Resort

14. Wekopa Casino Resort

15. Tru By Hilton Scottsdale Salt River

16. Hampton Inn & Suites Scottsdale at Talking Stick

17. Embassy Suites by Hilton Phoenix Scottsdale

18. Holiday Inn Express Scottsdale North by IHG

19. ADERO Scottsdale Resort, Autograph Collection

20. Holiday Inn & Suites Scottsdale North - Airpark by IHG

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Staybridge Suites Scottsdale - Talking Stick by IHG

Sonesta Select Scottsdale at Mayo Clinic Campus

Comfort Suites Scottsdale Talking Stick Entertainment District

ADERO Scottsdale Resort, Autograph Collection

Inn at Eagle Mountain

Aiden by Best Western Scottsdale North

Sonesta Simply Suites Phoenix Scottsdale

Fountain Park Hotel, BW Signature Collection

Wekopa Casino Resort

Frequently asked questions

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