The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

A breakfast buffet area with various pastries and a sign indicating the price of a cheese danish.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

louis

NT$3,195

NT$3,641 total

includes taxes & fees

Nov 22 - Nov 23

A cluster of modern, multi-story buildings with a river in the foreground.

A dining area with a glass table, wooden chairs, and potted plants.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

A golf course with a pond, a clubhouse, and a hilly backdrop.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Stephanie

NT$4,190

NT$4,784 total

includes taxes & fees

Oct 25 - Oct 26

A motel sign with neon lights spelling 'MOTEL' and a green banner with 'Starline Motel' text.

A bedroom with a bed, a lamp, an air conditioning unit, and curtains.

A living room with a sofa, a coffee table, and a kitchen area with a refrigerator and microwave.

A room with a red chair, a wooden cabinet with a television, and a large mirror on the wall.

3. Starlite Motel

19 km from Mayo Clinic Scottsdale

Virginia

NT$3,092

NT$3,533 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

A bar area with a long counter, multiple bar stools, and overhead lighting.

A hotel room with two beds, a desk, a sofa, and a TV.

A multi-story hotel with a parking lot and a road leading to a roundabout.

4. Hyatt Place Scottsdale - North

14.1 km from Mayo Clinic Scottsdale

Ted

NT$5,249

NT$5,982 total

includes taxes & fees

Nov 22 - Nov 23

A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and a television screen.

A bar area with multiple seating options, a bar counter, and a television screen displaying sports.

A spacious hotel lobby with a reception desk, seating areas, and a view of the dining and kitchen areas.

A multi-story hotel with a flat roof and balconies, surrounded by well-maintained grass and trees.

5. Embassy Suites by Hilton Phoenix Scottsdale

17.8 km from Mayo Clinic Scottsdale

Matthew

NT$4,785

NT$5,411 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor lounge area with white sofas, a fire pit, and a pool in the background.

A modern outdoor lounge area with white furniture, a pool, and large umbrellas.

A modern kitchen with a bar area, bar stools, and a dining table with chairs.

A modern hotel lobby with a long seating area, a reception desk, and large windows providing natural light.

6. AC Hotel by Marriott Scottsdale North

Paradise Valley Village, 13.4 km from Mayo Clinic Scottsdale

Laura

NT$4,687

NT$5,300 total

includes taxes & fees

Nov 22 - Nov 23

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

A bar area with a bar counter, multiple chairs, and a sofa.

7. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

Marie

NT$3,330

NT$3,795 total

includes taxes & fees

Oct 26 - Oct 27

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

A modern hotel lobby with a central bar area, seating arrangements, and a clean, contemporary design.

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

8. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

LAURA

NT$3,545

NT$4,042 total

includes taxes & fees

Nov 1 - Nov 2

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.

A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

9. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Joseph

NT$2,877

NT$3,279 total

includes taxes & fees

Oct 26 - Oct 27

A resort with multiple buildings, a large pool area, and surrounding mountains.

A dining area with a table and chairs, a view of a cityscape, and decorative wall panels.

Three people in a swimming pool with rocks and a red umbrella in the background.

A dining area with a table set for six, overlooking a scenic landscape.

10. ADERO Scottsdale Resort, Autograph Collection

3.6 km from Mayo Clinic Scottsdale

Garrett

NT$6,748

NT$9,007 total

includes taxes & fees

Oct 25 - Oct 26

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.

A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

11. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Colleen

NT$3,713

NT$4,234 total

includes taxes & fees

Nov 8 - Nov 9

A swimming pool with a bridge structure, surrounded by buildings with outdoor seating and a clear sky.

A reception area with a blue counter, a television screen, and a modern interior design.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.

A hotel room with a sofa, a chair, a desk with a television, a lamp, and a framed artwork on the wall.

12. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Ally Marie

NT$4,140

NT$4,719 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

A swimming pool with people on inflatable floats, lounge chairs, and umbrellas in the background.

A spacious lobby with a stone wall, a fireplace, and a seating area with a sofa and chairs.

13. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Linda

NT$3,793

NT$5,299 total

includes taxes & fees

Oct 26 - Oct 27

A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.

A restaurant with multiple round tables and bar stools, a self-service beverage dispenser, and a television mounted on the wall.

A modern lobby with a brick wall, seating area, and a flat-screen TV.

A modern hotel with a covered entrance, multiple floors, and a parking lot.

14. Hyatt Place Phoenix/Mesa

17.8 km from Mayo Clinic Scottsdale

Laura

NT$4,401

NT$5,029 total

includes taxes & fees

Nov 22 - Nov 23

A spacious lobby with a modern staircase, a comfortable seating area, and a large window providing natural light.

A hotel pool area with two hot tubs and lounge chairs.

A hotel reception area with a reception desk, a large mirror, framed pictures on the wall, a potted plant, and a welcome mat.

A patio area with wicker furniture, a large umbrella, and a pool in the background.

15. Sleep Inn North Scottsdale near Mayo Clinic

Paradise Valley Village, 13.5 km from Mayo Clinic Scottsdale

Margret

NT$3,575

NT$4,042 total

includes taxes & fees

Nov 22 - Nov 23

A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.

An outdoor patio area with stone pillars, fire pit seating, and tables.

A Hampton Inn & Suites with a stone facade, a welcoming entrance, and a clear sky at dusk.

A modern kitchen with dark wooden cabinets, a white countertop, and a black refrigerator.

16. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Central Scottsdale, 12.3 km from Mayo Clinic Scottsdale

Dana

NT$4,628

NT$5,274 total

includes taxes & fees

Nov 23 - Nov 24

An outdoor seating area with fire pit, red Adirondack chairs, and a covered patio with string lights.

A multi-story hotel with a modern design, featuring a prominent 'Home Suites by Hilton' sign.

A modern lounge area with vibrant seating, a central table, and a kitchen area in the background.

A modern hotel room with a dining area, a bed, a desk, and a view of the city.

17. Home2 Suites by Hilton Scottsdale North

15 km from Mayo Clinic Scottsdale

Theresa

NT$4,295

NT$4,895 total

includes taxes & fees

Nov 22 - Nov 23

A modern outdoor seating area with sofas and a central fire feature.

A hotel courtyard with a swimming pool, palm trees, and a covered seating area.

A modern hotel lobby with a white sofa, armchairs, a coffee table, and a dining area with chairs and a table. Large windows provide a view of the outdoors.

A modern hotel with a prominent entrance, multiple floors, and a clear sky.

18. Delta Hotels by Marriott Phoenix Mesa

18.7 km from Mayo Clinic Scottsdale

Kasey

NT$3,483

NT$3,980 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, desk, chair, television, fireplace, and a dining area.

A reception area with a counter, two armchairs, and a round table.

An outdoor patio with a grill, table, and chairs.

A breakfast buffet with various food items and a coffee machine.

19. Sonesta ES Suites Scottsdale Paradise Valley

14 km from Mayo Clinic Scottsdale

Denine

NT$3,880

NT$4,421 total

includes taxes & fees

Nov 24 - Nov 25

A modern hotel with a flat roof, multiple floors, and a sign indicating 'Springhill Suites'.

A hotel room with a wooden desk, a flat-screen TV, a sofa, and a tray table with a book.

A modern hotel lobby with multiple seating areas, a reception desk, and a large flat-screen TV mounted on the wall.

20. SpringHill Suites Scottsdale North

13.8 km from Mayo Clinic Scottsdale

Charlene

NT$3,852

NT$4,355 total

includes taxes & fees

Nov 22 - Nov 23

View all properties

Top Mayo Clinic Scottsdale Hotel Reviews

ADERO Scottsdale Resort, Autograph Collection

10/10 Excellent

"One of the best places I’ve ever stayed. The views are magnificent. Nothing else in the world like it."

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

10/10 Excellent

"Everything was wonderful"

Inn at Eagle Mountain

8/10 Good

"I think I was able to get one of the last rooms same day....beautiful room, comfortable and spacious, bathroom as well. My view was the parking lot, but next time I will book in advance for hopefully a valley view. Friendly young front desk rep offering wine tasting at that time."

Aiden by Best Western Scottsdale North

8/10 Good

"Room was not done at check in"

Sonesta Simply Suites Phoenix Scottsdale

10/10 Excellent

"Great price! It was actually a suitet with a kitchenette although I didn't use it. I would definitely stay there again if I was in the area!"

Fountain Park Hotel, BW Signature Collection

10/10 Excellent

"Everything was in order. No issues, helpful staff and a good location"

Wekopa Casino Resort

10/10 Excellent

"We had fun at the slot machines over the Fri-Sat weekend. Hotel is clean and decent. They had healthy options at the fast food. We'll be back."

Sonesta Select Scottsdale at Mayo Clinic Campus

10/10 Excellent

"very clean well appointed helpful staff shuttle was great parking lot could use repaving"

Spark by Hilton Fountain Hills Scottsdale

8/10 Good

"Excellent value for a traveler."

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$3,279

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. Starlite Motel

4. Hyatt Place Scottsdale - North

5. Embassy Suites by Hilton Phoenix Scottsdale

6. AC Hotel by Marriott Scottsdale North

7. Aiden by Best Western Scottsdale North

8. Comfort Suites Scottsdale Talking Stick Entertainment District

9. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

10. ADERO Scottsdale Resort, Autograph Collection

11. Tru By Hilton Scottsdale Salt River

12. Holiday Inn & Suites Scottsdale North - Airpark by IHG

13. Wekopa Casino Resort

14. Hyatt Place Phoenix/Mesa

15. Sleep Inn North Scottsdale near Mayo Clinic

16. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

17. Home2 Suites by Hilton Scottsdale North

18. Delta Hotels by Marriott Phoenix Mesa

19. Sonesta ES Suites Scottsdale Paradise Valley

20. SpringHill Suites Scottsdale North

Top Mayo Clinic Scottsdale Hotel Reviews

ADERO Scottsdale Resort, Autograph Collection

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Inn at Eagle Mountain

Aiden by Best Western Scottsdale North

Sonesta Simply Suites Phoenix Scottsdale

Fountain Park Hotel, BW Signature Collection

Wekopa Casino Resort

Sonesta Select Scottsdale at Mayo Clinic Campus

Spark by Hilton Fountain Hills Scottsdale

Frequently asked questions

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