The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A cluster of modern, multi-story buildings with a river in the foreground.

A golf course with a pond, a clubhouse, and a hilly backdrop.

A dining area with a glass table, wooden chairs, and potted plants.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

1. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Stephanie

NT$4,185

NT$4,778 total

includes taxes & fees

Oct 25 - Oct 26

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A breakfast buffet area with various pastries and a sign indicating the price of a cheese danish.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

2. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

louis

NT$3,478

NT$3,964 total

includes taxes & fees

Oct 26 - Oct 27

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Wilson

NT$2,874

NT$3,275 total

includes taxes & fees

Oct 26 - Oct 27

A spacious living area with a kitchen, modern furniture, and a fireplace.

A spacious lobby with a high ceiling, modern chandeliers, a fire feature, and a large TV screen.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

4. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

NT$3,868

NT$4,417 total

includes taxes & fees

Oct 26 - Oct 27

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

A bar area with a bar counter, multiple chairs, and a sofa.

A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

5. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

Marie

NT$3,326

NT$3,791 total

includes taxes & fees

Oct 26 - Oct 27

A modern office space with multiple desks, chairs, and a meeting area.

A hotel room with a large bed, a desk with a phone, a chair, a desk lamp, a painting, and a view of the outdoors.

A hotel room with two beds, a desk, a TV, and a balcony with a view.

A reception area with a wooden counter, a large abstract painting above it, and a green carpet. There are shelves with bottled water and snacks on the right.

6. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Herlyn

NT$2,772

NT$3,165 total

includes taxes & fees

Oct 27 - Oct 28

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A lounge area with a grand piano, blue seating, and a stone wall.

A golf course with a mountain backdrop, surrounded by desert vegetation.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

7. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Ann

NT$3,797

NT$5,305 total

includes taxes & fees

Oct 25 - Oct 26

A living room with a sofa, a coffee table, and a kitchen area with a refrigerator and microwave.

A room with a red chair, a wooden cabinet with a television, and a large mirror on the wall.

A kitchen with granite countertops, a stove, a sink, and a microwave.

A bedroom with a bed, a lamp, an air conditioning unit, and curtains.

8. Starlite Motel

19 km from Mayo Clinic Scottsdale

Virginia

NT$3,088

NT$3,529 total

includes taxes & fees

Oct 23 - Oct 24

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

A modern hotel lobby with a central bar area, seating arrangements, and a clean, contemporary design.

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

9. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

LAURA

NT$3,540

NT$4,036 total

includes taxes & fees

Nov 1 - Nov 2

A landscaped garden with a fountain, palm trees, and a building with a red roof.

A courtyard with palm trees, a fountain, and a bench.

A pool area with a rock formation, palm trees, and lounge chairs.

A modern kitchen with a glass dining table, bar stools, and a built-in island with a microwave and oven.

10. Westgate Painted Mountain Golf Resort

17.4 km from Mayo Clinic Scottsdale

Tammie

NT$3,270

NT$3,736 total

includes taxes & fees

Nov 3 - Nov 4

A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.

A modern lobby with a brick wall, seating area, and a flat-screen TV.

A hotel room with two beds, a TV, a desk, a chair, and a view of palm trees.

A modern hotel with a covered entrance, multiple floors, and a parking lot.

11. Hyatt Place Phoenix/Mesa

17.8 km from Mayo Clinic Scottsdale

greg

NT$4,406

NT$5,035 total

includes taxes & fees

Oct 29 - Oct 30

A modern outdoor seating area with sofas and a central fire feature.

A hotel lobby with a tiled floor, a large chandelier, and a sign for the Arizona Ballroom.

A modern hotel with a prominent entrance, multiple floors, and a clear sky.

A modern hotel lobby with a white sofa, armchairs, a coffee table, and a dining area with chairs and a table. Large windows provide a view of the outdoors.

12. Delta Hotels by Marriott Phoenix Mesa

18.7 km from Mayo Clinic Scottsdale

Samantha

NT$3,478

NT$3,975 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, desk, chair, television, fireplace, and a dining area.

An outdoor patio with a grill, table, and chairs.

A hotel room with a bed, a desk with a TV, a sofa, and a coffee table.

A breakfast buffet with various food items and a coffee machine.

13. Sonesta ES Suites Scottsdale Paradise Valley

14 km from Mayo Clinic Scottsdale

Denine

NT$4,129

NT$4,705 total

includes taxes & fees

Oct 27 - Oct 28

A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.

A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows and a covered patio area.

An outdoor patio area with stone pillars, fire pit seating, and tables.

A Hampton Inn & Suites with a stone facade, a welcoming entrance, and a clear sky at dusk.

14. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Central Scottsdale, 12.3 km from Mayo Clinic Scottsdale

Dana

NT$4,946

NT$5,637 total

includes taxes & fees

Oct 27 - Oct 28

A spacious lobby with a large seating area, a reception desk, and artwork on the walls.

A buffet counter with various food items, a refrigerator, and a wall-mounted clock.

15. Best Western Plus Scottsdale Thunderbird Suites

Thunderbird Industrial Airpark, 12.1 km from Mayo Clinic Scottsdale

Susan

NT$3,753

NT$4,277 total

includes taxes & fees

Oct 27 - Oct 28

A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and a television screen.

A bar area with multiple seating options, a bar counter, and a television screen displaying sports.

A spacious hotel lobby with a reception desk, seating areas, and a view of the dining and kitchen areas.

An outdoor seating area with a fire feature, surrounded by a fence and palm trees, under a sunset sky.

16. Embassy Suites by Hilton Phoenix Scottsdale

17.8 km from Mayo Clinic Scottsdale

Matthew

NT$5,065

NT$5,727 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.

A hotel room with a desk, chair, television, lamp, and a framed artwork on the wall.

A swimming pool with lounge chairs and umbrellas, surrounded by a fence and palm trees.

A hotel breakfast area with a self-serve station, seating, and a trash bin.

17. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Melanie

NT$3,283

NT$3,742 total

includes taxes & fees

Oct 26 - Oct 27

An indoor water park with slides, a wave pool, and seating areas.

A modern bar area with a long counter, multiple stools, and a view through large windows.

An indoor adventure park with rope bridges, climbing structures, and a large bear statue.

An indoor play area with a rope bridge, climbing structures, and a picnic table.

18. Great Wolf Lodge Arizona

10.2 km from Mayo Clinic Scottsdale

Dejanira

NT$5,167

NT$6,047 total

includes taxes & fees

Nov 9 - Nov 10

A swimming pool with a water slide, a sun lounger, and a covered seating area.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.

A hotel room with a sofa, a chair, a desk with a television, a lamp, and a framed artwork on the wall.

A reception area with a blue counter, a television screen, and a modern interior design.

19. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Ally Marie

NT$5,091

NT$5,803 total

includes taxes & fees

Nov 8 - Nov 9

An outdoor patio area with round tables and chairs, a pool in the background, and a covered seating area.

A hotel room with a desk, a bed, a TV, a sofa, a small table, and a view of the outdoors.

A multi-story hotel with illuminated signage reading "Talking Stick" and "Resort".

A hotel reception area with a large bridge mural, a reception desk, and a snack bar.

20. Staybridge Suites Scottsdale - Talking Stick by IHG

9.7 km from Mayo Clinic Scottsdale

Steve

NT$5,364

NT$6,116 total

includes taxes & fees

Oct 26 - Oct 27

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Inn at Eagle Mountain	9.0 Wonderful 1,028 reviews	View
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very good 1,090 reviews	View
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale	8.8 Excellent 1,881 reviews	View
Fountain Park Hotel, BW Signature Collection	9.0 Wonderful 1,000 reviews	View
Aiden by Best Western Scottsdale North	9.0 Wonderful 1,191 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Sonesta Select Scottsdale at Mayo Clinic Campus

10/10 Excellent

"Free shuttle to mayo was nice."

Home2 Suites by Hilton Scottsdale Salt River

10/10 Excellent

"Everything was perfect. Coffee ready in lobby at 4am every morning!"

Talking Stick Resort

10/10 Excellent

"Loved it"

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

10/10 Excellent

"The staff was exceptionally helpful and kind."

Wekopa Casino Resort

8/10 Good

"The sports bar was amazing and food was very reasonably priced."

Spark by Hilton Fountain Hills Scottsdale

8/10 Good

"Clean rooms although a slightly weird smell in our room when we arrived. Nothing gross just odd but it went away. Very nice and attentive staff. The continental breakfast could be a little bit nicer, but I definitely think for the size and quality of the hotel, It was expected."

Holiday Inn & Suites Scottsdale North - Airpark by IHG

10/10 Excellent

"Wonderful personnel, clean environment and easy access to restaurants etc. The only down was the towels were very scratchy. The free Lyft was so convenient and easy to use. I really enjoyed my week."

Sonesta Simply Suites Phoenix Scottsdale

10/10 Excellent

"W"

Tru By Hilton Scottsdale Salt River

10/10 Excellent

"Very clean rooms and the staff very polite and friendly,"

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$3,165

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Our top choices for Mayo Clinic Scottsdale hotels

1. Inn at Eagle Mountain

2. Sonesta Select Scottsdale at Mayo Clinic Campus

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

4. Fountain Park Hotel, BW Signature Collection

5. Aiden by Best Western Scottsdale North

6. Spark by Hilton Fountain Hills Scottsdale

7. Wekopa Casino Resort

8. Starlite Motel

9. Comfort Suites Scottsdale Talking Stick Entertainment District

10. Westgate Painted Mountain Golf Resort

11. Hyatt Place Phoenix/Mesa

12. Delta Hotels by Marriott Phoenix Mesa

13. Sonesta ES Suites Scottsdale Paradise Valley

14. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

15. Best Western Plus Scottsdale Thunderbird Suites

16. Embassy Suites by Hilton Phoenix Scottsdale

17. Holiday Inn Express Scottsdale North by IHG

18. Great Wolf Lodge Arizona

19. Holiday Inn & Suites Scottsdale North - Airpark by IHG

20. Staybridge Suites Scottsdale - Talking Stick by IHG

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Sonesta Select Scottsdale at Mayo Clinic Campus

Home2 Suites by Hilton Scottsdale Salt River

Talking Stick Resort

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Wekopa Casino Resort

Spark by Hilton Fountain Hills Scottsdale

Holiday Inn & Suites Scottsdale North - Airpark by IHG

Sonesta Simply Suites Phoenix Scottsdale

Tru By Hilton Scottsdale Salt River

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