The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

A breakfast buffet area with various pastries and a sign indicating the price of a cheese danish.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

louis

NT$3,195

NT$3,641 total

includes taxes & fees

Nov 22 - Nov 23

A cluster of modern, multi-story buildings with a river in the foreground.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

A dining area with a glass table, wooden chairs, and potted plants.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Stephanie

NT$4,190

NT$4,784 total

includes taxes & fees

Oct 25 - Oct 26

A living room with a sofa, a coffee table, and a kitchen area with a refrigerator and microwave.

A kitchen with granite countertops, a stove, a sink, and a microwave.

A bedroom with a bed, a lamp, an air conditioning unit, and curtains.

A row of single-story buildings with a parking lot in between, surrounded by palm trees.

3. Starlite Motel

19 km from Mayo Clinic Scottsdale

Virginia

NT$3,092

NT$3,533 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

A hotel room with two beds, a desk, a sofa, and a TV.

A bar area with a long counter, multiple bar stools, and overhead lighting.

A spacious living area with a sofa, armchairs, and a coffee table. There is a TV mounted on the wall and a balcony with outdoor seating.

4. Hyatt Place Scottsdale - North

14.1 km from Mayo Clinic Scottsdale

Ted

NT$5,249

NT$5,982 total

includes taxes & fees

Nov 22 - Nov 23

A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and a television screen.

A multi-story hotel with a flat roof and balconies, surrounded by well-maintained grass and trees.

A bar area with multiple seating options, a bar counter, and a television screen displaying sports.

A spacious hotel lobby with a reception desk, seating areas, and a view of the dining and kitchen areas.

5. Embassy Suites by Hilton Phoenix Scottsdale

17.8 km from Mayo Clinic Scottsdale

Matthew

NT$4,785

NT$5,411 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor lounge area with white sofas, a fire pit, and a pool in the background.

A modern hotel lobby with a long seating area, a reception desk, and large windows providing natural light.

A spacious hotel lobby with modern furniture, large windows, and a flat-screen TV.

A modern outdoor lounge area with white furniture, a pool, and large umbrellas.

6. AC Hotel by Marriott Scottsdale North

Paradise Valley Village, 13.4 km from Mayo Clinic Scottsdale

Laura

NT$4,680

NT$5,292 total

includes taxes & fees

Nov 23 - Nov 24

A restaurant setting with round tables, chairs, and empty wine glasses.

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A bar area with a bar counter, multiple chairs, and a sofa.

A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.

7. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

Marie

NT$3,253

NT$3,707 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

A modern hotel lobby with a central bar area, seating arrangements, and a clean, contemporary design.

8. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

LAURA

NT$3,545

NT$4,042 total

includes taxes & fees

Nov 1 - Nov 2

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

9. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Joseph

NT$2,877

NT$3,279 total

includes taxes & fees

Oct 26 - Oct 27

A resort with multiple buildings, a large pool area, and surrounding mountains.

A dining area with a table set for six, overlooking a scenic landscape.

A dining area with a table and chairs, a view of a cityscape, and decorative wall panels.

Three people in a swimming pool with rocks and a red umbrella in the background.

10. ADERO Scottsdale Resort, Autograph Collection

3.6 km from Mayo Clinic Scottsdale

Garrett

NT$6,738

NT$8,993 total

includes taxes & fees

Oct 25 - Oct 26

A swimming pool with a bridge structure, surrounded by buildings with outdoor seating and a clear sky.

A reception area with a blue counter, a television screen, and a modern interior design.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.

A hotel room with a sofa, a chair, a desk with a television, a lamp, and a framed artwork on the wall.

11. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Ally Marie

NT$4,140

NT$4,719 total

includes taxes & fees

Nov 22 - Nov 23

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

12. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Colleen

NT$3,707

NT$4,227 total

includes taxes & fees

Nov 8 - Nov 9

A swimming pool with people on inflatable floats, lounge chairs, and umbrellas in the background.

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A dining area with a large table set for six, surrounded by chairs, with a view of cacti and a stone wall outside.

A spacious lobby with a stone wall, a fireplace, and a seating area with a sofa and chairs.

13. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Linda

NT$3,793

NT$5,299 total

includes taxes & fees

Oct 26 - Oct 27

A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.

A hotel room with two beds, a TV, a desk, a chair, and a view of palm trees.

A modern hotel with a covered entrance, multiple floors, and a parking lot.

A modern lobby with a brick wall, seating area, and a flat-screen TV.

14. Hyatt Place Phoenix/Mesa

17.8 km from Mayo Clinic Scottsdale

Laura

NT$4,401

NT$5,029 total

includes taxes & fees

Nov 22 - Nov 23

A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.

A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows and a covered patio area.

A Hampton Inn & Suites with a stone facade, a welcoming entrance, and a clear sky at dusk.

A modern kitchen with dark wooden cabinets, a white countertop, and a black refrigerator.

15. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Central Scottsdale, 12.3 km from Mayo Clinic Scottsdale

Dana

NT$4,628

NT$5,274 total

includes taxes & fees

Nov 23 - Nov 24

A spacious lobby with a modern staircase, a comfortable seating area, and a large window providing natural light.

A hotel room with two beds, a nightstand, a lamp, and framed pictures on the wall.

A hotel pool area with two hot tubs and lounge chairs.

A patio area with wicker furniture, a large umbrella, and a pool in the background.

16. Sleep Inn North Scottsdale near Mayo Clinic

Paradise Valley Village, 13.5 km from Mayo Clinic Scottsdale

Margret

NT$3,575

NT$4,042 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor seating area with fire pit, red Adirondack chairs, and a covered patio with string lights.

A modern hotel room with a dining area, a bed, a desk, and a view of the city.

A modern lounge area with vibrant seating, a central table, and a kitchen area in the background.

A multi-story hotel with a modern design, featuring a prominent 'Home Suites by Hilton' sign.

17. Home2 Suites by Hilton Scottsdale North

15 km from Mayo Clinic Scottsdale

Greta

NT$4,295

NT$4,895 total

includes taxes & fees

Nov 22 - Nov 23

A hotel room with a bed, desk, chair, television, fireplace, and a dining area.

A hotel room with a bed, a desk with a TV, a sofa, and a coffee table.

A reception area with a counter, two armchairs, and a round table.

An outdoor patio with a grill, table, and chairs.

18. Sonesta ES Suites Scottsdale Paradise Valley

14 km from Mayo Clinic Scottsdale

Denine

NT$3,880

NT$4,421 total

includes taxes & fees

Nov 24 - Nov 25

A modern hotel with a flat roof, multiple floors, and a sign indicating 'Springhill Suites'.

A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows and a covered seating area.

A modern hotel lobby with multiple seating areas, a reception desk, and a large flat-screen TV mounted on the wall.

A hotel room with a wooden desk, a flat-screen TV, a sofa, and a tray table with a book.

19. SpringHill Suites Scottsdale North

13.8 km from Mayo Clinic Scottsdale

Charlene

NT$3,852

NT$4,355 total

includes taxes & fees

Nov 22 - Nov 23

A hotel with a modern design, featuring a curved roof, large windows, and a landscaped entrance area with palm trees and shrubs.

A buffet with labeled trays of turkey sausage and cookies.

A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.

A hotel gym with dumbbells on racks, a bench, and a mirror.

20. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Melanie

NT$3,195

NT$3,641 total

includes taxes & fees

Nov 23 - Nov 24

View all properties

Top Mayo Clinic Scottsdale Hotel Reviews

Sonesta Simply Suites Phoenix Scottsdale

10/10 Excellent

"Great price! It was actually a suitet with a kitchenette although I didn't use it. I would definitely stay there again if I was in the area!"

Fountain Park Hotel, BW Signature Collection

10/10 Excellent

"Everything was in order. No issues, helpful staff and a good location"

Inn at Eagle Mountain

8/10 Good

"Place is always very clean!!!! Great view, quiet!! WiFi is not great!!! Cuts in and out. Mostly out°"

Wekopa Casino Resort

10/10 Excellent

"We had fun at the slot machines over the Fri-Sat weekend. Hotel is clean and decent. They had healthy options at the fast food. We'll be back."

ADERO Scottsdale Resort, Autograph Collection

8/10 Good

"The hotel was very nice, I loved the bar and how close my room was towards the entrance. Room service was very slow when I was in need of extra towels. But other than that it was great."

Sonesta Select Scottsdale at Mayo Clinic Campus

10/10 Excellent

"very clean well appointed helpful staff shuttle was great parking lot could use repaving"

Spark by Hilton Fountain Hills Scottsdale

8/10 Good

"Excellent value for a traveler."

Staybridge Suites Scottsdale - Talking Stick by IHG

10/10 Excellent

"Nice place tho the handicapped rooms weren’t available and we were put far from the elevators"

Home2 Suites by Hilton Scottsdale Salt River

10/10 Excellent

"Everything was perfect. Coffee ready in lobby at 4am every morning!"

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$3,279

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. Starlite Motel

4. Hyatt Place Scottsdale - North

5. Embassy Suites by Hilton Phoenix Scottsdale

6. AC Hotel by Marriott Scottsdale North

7. Aiden by Best Western Scottsdale North

8. Comfort Suites Scottsdale Talking Stick Entertainment District

9. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

10. ADERO Scottsdale Resort, Autograph Collection

11. Holiday Inn & Suites Scottsdale North - Airpark by IHG

12. Tru By Hilton Scottsdale Salt River

13. Wekopa Casino Resort

14. Hyatt Place Phoenix/Mesa

15. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

16. Sleep Inn North Scottsdale near Mayo Clinic

17. Home2 Suites by Hilton Scottsdale North

18. Sonesta ES Suites Scottsdale Paradise Valley

19. SpringHill Suites Scottsdale North

20. Holiday Inn Express Scottsdale North by IHG

Top Mayo Clinic Scottsdale Hotel Reviews

Sonesta Simply Suites Phoenix Scottsdale

Fountain Park Hotel, BW Signature Collection

Inn at Eagle Mountain

Wekopa Casino Resort

ADERO Scottsdale Resort, Autograph Collection

Sonesta Select Scottsdale at Mayo Clinic Campus

Spark by Hilton Fountain Hills Scottsdale

Staybridge Suites Scottsdale - Talking Stick by IHG

Home2 Suites by Hilton Scottsdale Salt River

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