The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

A breakfast buffet area with various pastries and a sign indicating the price of a cheese danish.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

Chad

NT$2,262

NT$2,578 total

includes taxes & fees

Aug 30 - Aug 31

A cluster of modern, multi-story buildings with a river in the foreground.

A dining area with a glass table, wooden chairs, and potted plants.

A golf course with a pond, a clubhouse, and a hilly backdrop.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Lucia

NT$2,817

NT$3,216 total

includes taxes & fees

Aug 25 - Aug 26

A spacious dining area with multiple tables and chairs, large windows, and a television mounted on the wall.

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

3. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

Cecilia

NT$2,351

NT$2,681 total

includes taxes & fees

Aug 31 - Sep 1

A well-maintained courtyard with a gazebo, palm trees, and a pathway leading to a building with a grey facade.

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

4. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Caroline

NT$2,122

NT$2,418 total

includes taxes & fees

Sep 1 - Sep 2

A modern infinity pool with a view of mountains and a sunset.

An outdoor seating area with fire pits and lounge chairs, surrounded by trees and a building with illuminated windows in the background.

A restaurant with high tables and booths, floral wall decorations, and a view of the mountains.

A modern bar area with a unique ceiling design, a bar counter with multiple screens, and a patterned carpet.

5. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Daryl

NT$3,798

NT$5,238 total

includes taxes & fees

Sep 7 - Sep 8

A spacious living area with a kitchen, modern furniture, and a fireplace.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

A spacious lobby with a high ceiling, modern chandeliers, a fire feature, and a large TV screen.

A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.

6. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

David

NT$2,676

NT$3,055 total

includes taxes & fees

Aug 25 - Aug 26

A hotel room with two beds, a TV, a desk, and a window with a view.

A modern office space with multiple desks, chairs, and a meeting area.

A modern hotel room with a large window, a desk with a lamp, a microwave, and a chair.

A hotel room with two beds, a desk, a TV, and a balcony with a view.

7. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Jim

NT$1,933

NT$2,207 total

includes taxes & fees

Aug 31 - Sep 1

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.

A bar area with a bar counter, multiple chairs, and a sofa.

8. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

cody

NT$2,504

NT$2,854 total

includes taxes & fees

Aug 26 - Aug 27

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

A bar area with a long counter, multiple bar stools, and overhead lighting.

A spacious living area with a sofa, armchairs, and a coffee table. There is a TV mounted on the wall and a balcony with outdoor seating.

A multi-story hotel with a parking lot and a road leading to a roundabout.

9. Hyatt Place North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Derrick

NT$2,166

NT$2,469 total

includes taxes & fees

Sep 6 - Sep 7

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

A spacious living area with a sofa, chairs, a coffee table, and a TV mounted on the wall.

A bar area with a long counter, multiple stools, and overhead pendant lighting.

A reception area with marble reception desks, a wooden ceiling, and a wall-mounted refrigerator.

10. Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Christopher

NT$2,676

NT$3,050 total

includes taxes & fees

Aug 30 - Aug 31

A pool area with a covered seating area, a staircase, and a building with large windows.

A breakfast bar with a variety of baked goods and a sign indicating fresh baked items.

A hotel room with a sofa, a chair, a desk with a television, a lamp, and a framed artwork on the wall.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.

11. Holiday Inn Hotel & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Christiaan Leonard

NT$2,676

NT$3,050 total

includes taxes & fees

Aug 30 - Aug 31

A resort with multiple buildings, a large pool area, and surrounding mountains.

A dining area with a table and chairs, a view of a cityscape, and decorative wall panels.

A dining area with a table set for six, overlooking a scenic landscape.

An outdoor wedding reception with round tables set with white chairs, floral centerpieces, and a view of the city in the background.

12. ADERO Scottsdale Resort, Autograph Collection

3.6 km from Mayo Clinic Scottsdale

Kristen

NT$3,536

NT$5,311 total

includes taxes & fees

Aug 27 - Aug 28

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A dining area with a large table set for six, surrounded by chairs, with a view of cacti and a stone wall outside.

A golf course with a mountain backdrop, surrounded by desert vegetation.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

13. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Kim

NT$3,497

NT$5,863 total

includes taxes & fees

Aug 25 - Aug 26

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.

An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

14. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Andrea

NT$2,403

NT$2,740 total

includes taxes & fees

Aug 31 - Sep 1

A circular fire feature with a stone border, surrounded by a landscaped garden with cacti and shrubs, under a sunset sky.

A modern bar area with seating, a digital menu display, and a beverage refrigerator.

A pool area with lounge chairs and umbrellas, surrounded by buildings with balconies and outdoor seating.

A modern lobby with a central water feature, seating area, and a stone pillar.

15. Courtyard Scottsdale Salt River

12.2 km from Mayo Clinic Scottsdale

Karl

NT$2,581

NT$2,941 total

includes taxes & fees

Sep 3 - Sep 4

A hotel pool area with sun loungers, a children's play area, and a building with a sign.

A modern kitchen with a central island, bar stools, and a sign that reads "inspired table".

A hotel room with a bed, a green sofa, a TV, a desk, and a green carpet.

16. Home2 Suites by Hilton Scottsdale Salt River

9.6 km from Mayo Clinic Scottsdale

Alfredo

NT$2,586

NT$2,949 total

includes taxes & fees

Sep 6 - Sep 7

A hotel room with a bed, desk, television, fireplace, and seating area.

A hotel room with a bed, a desk, a TV, a sofa, and a chair.

A breakfast buffet with various food items and a coffee machine.

An outdoor patio with a grill, table, and chairs.

17. Sonesta ES Suites Scottsdale Paradise Valley

14 km from Mayo Clinic Scottsdale

Jonathan

NT$2,262

NT$2,578 total

includes taxes & fees

Aug 30 - Aug 31

A modern kitchen with a central island, stainless steel appliances, and pendant lighting.

A Staybridge hotel with multiple floors, a parking lot, and landscaped areas with small trees and shrubs.

An outdoor patio area with round tables and chairs, a pool in the background, and a covered seating area.

A spacious lobby with two sofas, a coffee table, and a rug.

18. Staybridge Suites Scottsdale - Talking Stick by IHG

9.7 km from Mayo Clinic Scottsdale

Eric

NT$3,600

NT$4,105 total

includes taxes & fees

Sep 7 - Sep 8

A hotel dining area with a table and chairs, patterned curtains, and a view through large windows.

A hotel lobby with a bar area, seating, and a reception desk.

A building entrance with a stone facade, large glass doors, and potted plants.

A hotel room with a large window, a desk, a bed, a TV, and a chair.

19. Hampton Inn & Suites Scottsdale at Talking Stick

9.1 km from Mayo Clinic Scottsdale

Jesse

NT$2,803

NT$3,196 total

includes taxes & fees

Sep 6 - Sep 7

A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.

A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows and a covered patio area.

A modern kitchen with dark wooden cabinets, a white countertop, and a black refrigerator.

An outdoor patio area with stone pillars, fire pit seating, and tables.

20. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Central Scottsdale, 12.3 km from Mayo Clinic Scottsdale

Dana

NT$3,109

NT$3,543 total

includes taxes & fees

Aug 31 - Sep 1

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very Good 1,114 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,008 reviews	View
Comfort Suites Scottsdale Talking Stick Entertainment District	9.2 Wonderful 1,992 reviews	View
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale	8.8 Excellent 1,855 reviews	View
Talking Stick Resort	9.4 Exceptional 5,086 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Talking Stick Resort

10/10 Excellent

"Beautiful location! Restaurants were great along with staff!"

Hampton Inn & Suites Scottsdale at Talking Stick

8/10 Good

"We got a great price for a good sized room. Some of the furniture was a bit worn in the room but the room was clean. Nice breakfast or grab n go bags was available. The staff was very friendly. We will definitely stay again."

Great Wolf Lodge Arizona

10/10 Excellent

"We really enjoyed our stay. The room and property was clean and beautifully decorated. Lots of fun stuff to do. Waterpark was a blast. All of the staff was friendly and helpful."

Comfort Suites Scottsdale Talking Stick Entertainment District

10/10 Excellent

"Perfect stay except for the lobby smelled like wet dog."

Fountain Park Hotel, BW Signature Collection

10/10 Excellent

"Great breakfast and helpful staff. Plenty of parking and good location."

Tru By Hilton Scottsdale Salt River

10/10 Excellent

"My room was immaculate, the hotel was very clean, and the staff were very nice"

ADERO Scottsdale Resort, Autograph Collection

10/10 Excellent

"Everything was clean and the room was very spacious. The staff were friendly and it was peaceful."

Inn at Eagle Mountain

10/10 Excellent

"I don’t like checkout. I left 5:20am and unable to get final bill due to early Check lout. I notify them that I will be checking out early. They should give me final bill day prior."

Sonesta Select Scottsdale at Mayo Clinic Campus

10/10 Excellent

"Ice cold, clean room in hot AZ."

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 24 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 24 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, McDowell Mountain Golf Club, or Golf Club at Eagle Mountain are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,207

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Treat yourself

Be picky

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. Comfort Suites Scottsdale Talking Stick Entertainment District

4. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

5. Talking Stick Resort

6. Fountain Park Hotel, BW Signature Collection

7. Spark by Hilton Fountain Hills Scottsdale

8. Aiden by Best Western Scottsdale North

9. Hyatt Place North Scottsdale

10. Hyatt House North Scottsdale

11. Holiday Inn Hotel & Suites Scottsdale North - Airpark by IHG

12. ADERO Scottsdale Resort, Autograph Collection

13. Wekopa Casino Resort

14. Tru By Hilton Scottsdale Salt River

15. Courtyard Scottsdale Salt River

16. Home2 Suites by Hilton Scottsdale Salt River

17. Sonesta ES Suites Scottsdale Paradise Valley

18. Staybridge Suites Scottsdale - Talking Stick by IHG

19. Hampton Inn & Suites Scottsdale at Talking Stick

20. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Talking Stick Resort

Hampton Inn & Suites Scottsdale at Talking Stick

Great Wolf Lodge Arizona

Comfort Suites Scottsdale Talking Stick Entertainment District

Fountain Park Hotel, BW Signature Collection

Tru By Hilton Scottsdale Salt River

ADERO Scottsdale Resort, Autograph Collection

Inn at Eagle Mountain

Sonesta Select Scottsdale at Mayo Clinic Campus

Frequently asked questions

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