The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

Michael

NT$2,535

NT$2,889 total

includes taxes & fees

Oct 1 - Oct 2

A cluster of modern, multi-story buildings with a river in the foreground.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

A dining area with a glass table, wooden chairs, and potted plants.

A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Andrei

NT$3,587

NT$4,096 total

includes taxes & fees

Sep 27 - Sep 28

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Cathleen

NT$2,246

NT$2,559 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with two beds, a TV, a desk, and a window with a view.

A modern hotel room with a large window, a desk with a lamp, a microwave, and a chair.

A modern office space with multiple desks, chairs, and a meeting area.

A hotel room with two beds, a desk, a TV, and a balcony with a view.

4. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Peyton

NT$2,453

NT$2,801 total

includes taxes & fees

Oct 8 - Oct 9

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

A bar area with a long counter, multiple bar stools, and overhead lighting.

A multi-story hotel with a parking lot and a road leading to a roundabout.

A spacious living area with a sofa, armchairs, and a coffee table. There is a TV mounted on the wall and a balcony with outdoor seating.

5. Hyatt Place North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Ana

NT$3,412

NT$3,889 total

includes taxes & fees

Sep 27 - Sep 28

A spacious living area with a kitchen, modern furniture, and a fireplace.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

A spacious lobby with a high ceiling, modern chandeliers, a fire feature, and a large TV screen.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

6. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

NT$2,982

NT$3,405 total

includes taxes & fees

Oct 1 - Oct 2

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A lounge area with a grand piano, blue seating, and a stone wall.

A golf course with a mountain backdrop, surrounded by desert vegetation.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

7. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Darrick

NT$3,497

NT$5,861 total

includes taxes & fees

Sep 27 - Sep 28

A modern infinity pool with a view of mountains and a sunset.

A modern bar area with a unique ceiling design, a bar counter with multiple screens, and a patterned carpet.

An outdoor seating area with fire pits and lounge chairs, surrounded by trees and a building with illuminated windows in the background.

A poolside lounge with a view of a hotel building, a TV, and a bar area with a bottle of champagne.

8. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Meghan Rebbecca

NT$6,499

NT$8,318 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

9. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

William

NT$2,833

NT$3,230 total

includes taxes & fees

Sep 27 - Sep 28

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.

A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

10. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

cody

NT$2,741

NT$3,124 total

includes taxes & fees

Sep 27 - Sep 28

A circular fire feature with a stone border, surrounded by a landscaped garden with cacti and shrubs, under a sunset sky.

A Courtyard by Marriott hotel with a modern design, featuring a covered entrance and stone pillars.

A modern lobby with a central water feature, seating area, and a stone pillar.

A pool area with lounge chairs and umbrellas, surrounded by buildings with balconies and outdoor seating.

11. Courtyard Scottsdale Salt River

12.2 km from Mayo Clinic Scottsdale

Karl

NT$4,632

NT$5,279 total

includes taxes & fees

Oct 1 - Oct 2

A hotel pool area with sun loungers, a children's play area, and a building with a sign.

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

An outdoor patio area with round tables and white wicker chairs, red umbrellas, and potted plants.

A hotel room with a bed, a green sofa, a TV, a desk, and a green carpet.

12. Home2 Suites by Hilton Scottsdale Salt River

9.6 km from Mayo Clinic Scottsdale

Kate

NT$3,788

NT$4,319 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.

A hotel gym with dumbbells on racks, a bench, and a mirror.

A hotel room with a desk, chair, television, lamp, and a framed artwork on the wall.

A swimming pool with lounge chairs and umbrellas, surrounded by a fence and palm trees.

13. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Melanie

NT$2,674

NT$3,047 total

includes taxes & fees

Sep 29 - Sep 30

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.

14. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Colleen

NT$3,469

NT$3,956 total

includes taxes & fees

Sep 27 - Sep 28

A breakfast bar with a variety of baked goods and a sign indicating fresh baked items.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.

A hotel room with a sofa, a chair, a desk with a television, a lamp, and a framed artwork on the wall.

A hotel room with a flat-screen TV, a fireplace, a sofa, a coffee table, and a large window with a view.

15. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Christiaan Leonard

NT$4,042

NT$4,607 total

includes taxes & fees

Sep 29 - Sep 30

A hotel dining area with a table and chairs, patterned curtains, and a view through large windows.

A hotel lobby with a bar area, seating, and a reception desk.

A building entrance with a stone facade, large glass doors, and potted plants.

A hotel room with a large window, a desk, a bed, a TV, and a chair.

16. Hampton Inn & Suites Scottsdale at Talking Stick

9.1 km from Mayo Clinic Scottsdale

Michelle

NT$3,469

NT$3,956 total

includes taxes & fees

Sep 27 - Sep 28

A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.

A restaurant with multiple round tables and bar stools, a self-service beverage dispenser, and a television mounted on the wall.

A modern hotel with a covered entrance, multiple floors, and a parking lot.

A modern lobby with a brick wall, seating area, and a flat-screen TV.

17. Hyatt Place Phoenix/Mesa

17.8 km from Mayo Clinic Scottsdale

greg

NT$3,744

NT$4,278 total

includes taxes & fees

Oct 5 - Oct 6

A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.

A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows and a covered patio area.

A modern kitchen with dark wooden cabinets, a white countertop, and a black refrigerator.

A Hampton Inn & Suites with a stone facade, a welcoming entrance, and a clear sky at dusk.

18. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Central Scottsdale, 12.3 km from Mayo Clinic Scottsdale

Dana

NT$3,876

NT$4,418 total

includes taxes & fees

Oct 1 - Oct 2

A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and a television screen.

A spacious hotel lobby with a reception desk, seating areas, and a view of the dining and kitchen areas.

An outdoor seating area with a fire feature, surrounded by a fence and palm trees, under a sunset sky.

A bar area with multiple seating options, a bar counter, and a television screen displaying sports.

19. Embassy Suites by Hilton Phoenix Scottsdale

17.8 km from Mayo Clinic Scottsdale

Maria Antoinette

NT$4,411

NT$4,988 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor patio area with a central fire feature, seating arrangements, and a covered walkway.

A modern lounge area with dark blue upholstered chairs, round tables, and a leather sofa.

A modern lounge area with a large flat-screen TV, comfortable seating, and a large window offering a view of the outdoors.

A swimming pool with lounge chairs and umbrellas, surrounded by buildings with balconies and outdoor seating areas.

20. Residence Inn Scottsdale Salt River

12 km from Mayo Clinic Scottsdale

Michael

NT$5,570

NT$6,351 total

includes taxes & fees

Oct 2 - Oct 3

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very good 1,101 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,015 reviews	View
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale	8.8 Excellent 1,857 reviews	View
Spark by Hilton Fountain Hills Scottsdale	8.8 Excellent 317 reviews	View
Hyatt Place North Scottsdale	9.4 Exceptional 1,263 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Staybridge Suites Scottsdale - Talking Stick by IHG

10/10 Excellent

"The breakfast was fantastic!!"

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

10/10 Excellent

"Room very clean"

Hampton Inn & Suites Scottsdale at Talking Stick

10/10 Excellent

"Wonderfull Breakfast!!! Quiet and friendly!!! Thank you!!"

Holiday Inn & Suites Scottsdale North - Airpark by IHG

10/10 Excellent

"Clean room and helpful staff. Definitely would stay again"

Hilton Vacation Club Scottsdale Links Resort

10/10 Excellent

"Clean rooms"

Sonesta Select Scottsdale at Mayo Clinic Campus

8/10 Good

"Beds where comfortable, but the air conditioning unit in our room was so loud, my earplugs hardly drowned out the sound"

Inn at Eagle Mountain

8/10 Good

"Clean room staff was helpful balcony was nice and the parking was convenient"

Wekopa Casino Resort

10/10 Excellent

"It was a very nice stay."

ADERO Scottsdale Resort, Autograph Collection

10/10 Excellent

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Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 21 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 21 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,559

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

4. Spark by Hilton Fountain Hills Scottsdale

5. Hyatt Place North Scottsdale

6. Fountain Park Hotel, BW Signature Collection

7. Wekopa Casino Resort

8. Talking Stick Resort

9. Comfort Suites Scottsdale Talking Stick Entertainment District

10. Aiden by Best Western Scottsdale North

11. Courtyard Scottsdale Salt River

12. Home2 Suites by Hilton Scottsdale Salt River

13. Holiday Inn Express Scottsdale North by IHG

14. Tru By Hilton Scottsdale Salt River

15. Holiday Inn & Suites Scottsdale North - Airpark by IHG

16. Hampton Inn & Suites Scottsdale at Talking Stick

17. Hyatt Place Phoenix/Mesa

18. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

19. Embassy Suites by Hilton Phoenix Scottsdale

20. Residence Inn Scottsdale Salt River

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Staybridge Suites Scottsdale - Talking Stick by IHG

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Hampton Inn & Suites Scottsdale at Talking Stick

Holiday Inn & Suites Scottsdale North - Airpark by IHG

Hilton Vacation Club Scottsdale Links Resort

Sonesta Select Scottsdale at Mayo Clinic Campus

Inn at Eagle Mountain

Wekopa Casino Resort

ADERO Scottsdale Resort, Autograph Collection

Frequently asked questions

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