The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

Teri

NT$2,542

NT$2,897 total

includes taxes & fees

Sep 17 - Sep 18

A cluster of modern, multi-story buildings with a river in the foreground.

A golf course with a pond, a clubhouse, and a hilly backdrop.

A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Elizabeth

NT$3,547

NT$4,049 total

includes taxes & fees

Sep 20 - Sep 21

A hotel room with two beds, a TV, a desk, and a window with a view.

A modern office space with multiple desks, chairs, and a meeting area.

A pool area with a clear blue pool, lounge chairs, and a multi-story building with balconies.

A hotel room with two beds, a desk, a TV, and a balcony with a view.

3. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Jim

NT$1,928

NT$2,201 total

includes taxes & fees

Sep 27 - Sep 28

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

A bar area with a long counter, multiple bar stools, and overhead lighting.

A hotel room with two beds, a desk, a sofa, and a TV.

A spacious living area with a sofa, armchairs, and a coffee table. There is a TV mounted on the wall and a balcony with outdoor seating.

4. Hyatt Place North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Jamie A.

NT$2,898

NT$3,303 total

includes taxes & fees

Sep 21 - Sep 22

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

A Comfort Suites hotel with a modern design, featuring a covered entrance and a parking lot.

5. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

Brenda

NT$2,495

NT$2,845 total

includes taxes & fees

Sep 20 - Sep 21

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

6. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Steve

NT$2,250

NT$2,564 total

includes taxes & fees

Sep 20 - Sep 21

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

A golf course with a mountain backdrop, surrounded by desert vegetation.

A dining area with a large table set for six, surrounded by chairs, with a view of cacti and a stone wall outside.

7. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Kim

NT$4,028

NT$6,463 total

includes taxes & fees

Sep 21 - Sep 22

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

A bar area with a bar counter, multiple chairs, and a sofa.

8. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

cody

NT$2,362

NT$2,692 total

includes taxes & fees

Sep 17 - Sep 18

A spacious living area with a kitchen, modern furniture, and a fireplace.

A spacious lobby with a high ceiling, modern chandeliers, a fire feature, and a large TV screen.

A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

9. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

NT$2,975

NT$3,396 total

includes taxes & fees

Sep 22 - Sep 23

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.

10. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Andrea

NT$2,840

NT$3,238 total

includes taxes & fees

Sep 27 - Sep 28

A breakfast bar with a variety of baked goods and a sign indicating fresh baked items.

A reception area with a blue counter, a television screen, and a modern interior design.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.

A hotel room with a sofa, a chair, a desk with a television, a lamp, and a framed artwork on the wall.

11. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Christiaan Leonard

NT$3,622

NT$4,129 total

includes taxes & fees

Sep 18 - Sep 19

An outdoor dining table set with chairs, string lights, and a sunset view.

A modern lobby with a seating area, a kitchen, and a reception desk.

A modern living room with a sectional sofa, orange ottomans, a dining area, and a kitchen with a stone accent wall.

A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.

12. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Damon

NT$3,622

NT$4,139 total

includes taxes & fees

Sep 20 - Sep 21

A circular fire feature with a stone border, surrounded by a landscaped garden with cacti and shrubs, under a sunset sky.

A modern lobby with a central water feature, seating area, and a stone pillar.

A modern bar area with seating, a digital menu display, and a beverage refrigerator.

A Courtyard by Marriott hotel with a modern design, featuring a covered entrance and stone pillars.

13. Courtyard Scottsdale Salt River

12.2 km from Mayo Clinic Scottsdale

Karl

NT$3,495

NT$3,984 total

includes taxes & fees

Sep 27 - Sep 28

A hotel dining area with a table and chairs, patterned curtains, and a view through large windows.

A hotel room with a large window, a desk, a bed, a TV, and a chair.

A golf course with sand bunkers, a flagstick, and mountains in the background.

A building entrance with a stone facade, large glass doors, and potted plants.

14. Hampton Inn & Suites Scottsdale at Talking Stick

9.1 km from Mayo Clinic Scottsdale

Michelle

NT$2,840

NT$3,238 total

includes taxes & fees

Sep 27 - Sep 28

A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.

A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows and a covered patio area.

A Hampton Inn & Suites with a stone facade, a welcoming entrance, and a clear sky at dusk.

An outdoor patio area with stone pillars, fire pit seating, and tables.

15. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Central Scottsdale, 12.3 km from Mayo Clinic Scottsdale

Dana

NT$3,882

NT$4,425 total

includes taxes & fees

Sep 22 - Sep 23

A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.

A swimming pool with lounge chairs and umbrellas, surrounded by a fence and palm trees.

A hotel room with a desk, chair, television, lamp, and a framed artwork on the wall.

A hotel breakfast area with a self-serve station, seating, and a trash bin.

16. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Melanie

NT$2,539

NT$2,894 total

includes taxes & fees

Sep 17 - Sep 18

A resort with multiple buildings, a large pool area, and surrounding mountains.

Three people in a swimming pool with rocks and a red umbrella in the background.

A dining area with a table and chairs, a view of a cityscape, and decorative wall panels.

A dining area with a table set for six, overlooking a scenic landscape.

17. ADERO Scottsdale Resort, Autograph Collection

3.6 km from Mayo Clinic Scottsdale

Karen

NT$6,867

NT$9,104 total

includes taxes & fees

Sep 17 - Sep 18

A spacious lobby with stone walls, comfortable seating, and a large window offering a mountain view.

A spacious outdoor lounge area with a fire feature, comfortable seating, a bar with a view, and a stone wall.

A spacious restaurant with wooden flooring, high tables, and chairs, featuring a bar area and large windows overlooking a scenic view.

A spacious lobby with a central table set for a small gathering, flanked by seating and a modern ceiling design.

18. Hilton North Scottsdale At Cavasson

13.4 km from Mayo Clinic Scottsdale

Marcos

NT$5,188

NT$5,913 total

includes taxes & fees

Sep 27 - Sep 28

An outdoor patio area with round tables and chairs, a pool in the background, and a covered seating area.

A multi-story hotel with illuminated signage reading "Talking Stick" and "Resort".

A hotel room with a desk, a bed, a TV, a sofa, a small table, and a view of the outdoors.

A hotel reception area with a large bridge mural, a reception desk, and a snack bar.

19. Staybridge Suites Scottsdale - Talking Stick by IHG

9.7 km from Mayo Clinic Scottsdale

Friedemann

NT$3,619

NT$4,127 total

includes taxes & fees

Sep 17 - Sep 18

A hotel room with a bed, desk, television, fireplace, and seating area.

A reception area with a counter, two armchairs, and a round table.

A breakfast buffet with various food items and a coffee machine.

An outdoor patio with a grill, table, and chairs.

20. Sonesta ES Suites Scottsdale Paradise Valley

14 km from Mayo Clinic Scottsdale

Eriel

NT$2,753

NT$3,138 total

includes taxes & fees

Sep 22 - Sep 23

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very good 1,102 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,006 reviews	View
Spark by Hilton Fountain Hills Scottsdale	8.8 Excellent 314 reviews	View
Hyatt Place North Scottsdale	9.4 Exceptional 1,248 reviews	View
Comfort Suites Scottsdale Talking Stick Entertainment District	9.2 Wonderful 2,010 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Talking Stick Resort

10/10 Excellent

"The housekeeping and front desk staff were amazing. Room service was quick and efficient."

Fountain Park Hotel, BW Signature Collection

10/10 Excellent

"Great hotel I come here every time I’m in fountain hills"

Hilton Vacation Club Scottsdale Links Resort

10/10 Excellent

"The unit was exceptionally clean, spacious, and beautiful. Parking was easy and convenient. The swimming pools were the highlight. Definitely a place I would recommend and come back to. Five stars!"

Spark by Hilton Fountain Hills Scottsdale

10/10 Excellent

"Nice staff clean rooms great place to stay I have nothing to say so iam just writing whatever come to mind"

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

10/10 Excellent

"Thank you"

Sonesta Select Scottsdale at Mayo Clinic Campus

10/10 Excellent

"Property very clean, great staff. Shuttle to Mayo clinic on demand, very pleasant staff."

ADERO Scottsdale Resort, Autograph Collection

10/10 Excellent

"We loved our stay at Adero! Clean, beautiful amenities, wonderful staff and the food is fantastic!"

Holiday Inn & Suites Scottsdale North - Airpark by IHG

10/10 Excellent

"We weren’t there long, but the staff was friendly and willingly helpful. The room was spacious, clean, had everything we need. All for a reasonable price."

Tru By Hilton Scottsdale Salt River

10/10 Excellent

"This is the best place to stay. Great atmosphere"

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, SunRidge Canyon Golf Club, or McDowell Mountain Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,201

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. Spark by Hilton Fountain Hills Scottsdale

4. Hyatt Place North Scottsdale

5. Comfort Suites Scottsdale Talking Stick Entertainment District

6. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

7. Wekopa Casino Resort

8. Aiden by Best Western Scottsdale North

9. Fountain Park Hotel, BW Signature Collection

10. Tru By Hilton Scottsdale Salt River

11. Holiday Inn & Suites Scottsdale North - Airpark by IHG

12. Home2 Suites by Hilton Mesa Longbow, AZ

13. Courtyard Scottsdale Salt River

14. Hampton Inn & Suites Scottsdale at Talking Stick

15. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

16. Holiday Inn Express Scottsdale North by IHG

17. ADERO Scottsdale Resort, Autograph Collection

18. Hilton North Scottsdale At Cavasson

19. Staybridge Suites Scottsdale - Talking Stick by IHG

20. Sonesta ES Suites Scottsdale Paradise Valley

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Talking Stick Resort

Fountain Park Hotel, BW Signature Collection

Hilton Vacation Club Scottsdale Links Resort

Spark by Hilton Fountain Hills Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Sonesta Select Scottsdale at Mayo Clinic Campus

ADERO Scottsdale Resort, Autograph Collection

Holiday Inn & Suites Scottsdale North - Airpark by IHG

Tru By Hilton Scottsdale Salt River

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