The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A golf course with a pond, a clubhouse, and a hilly backdrop.

1. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

A Candy

NT$5,841 total

includes taxes & fees

Nov 18 - Nov 19

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

2. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

louis

NT$3,897 total

includes taxes & fees

Nov 22 - Nov 23

A modern infinity pool with a view of mountains and a sunset.

3. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Justin

NT$4,917 total

includes taxes & fees

Dec 14 - Dec 15

A modern lobby with a stone fireplace, comfortable seating, and a television.

4. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

LAURA

NT$3,914 total

includes taxes & fees

Nov 29 - Nov 30

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

5. Hyatt Place Scottsdale - North

14.1 km from Mayo Clinic Scottsdale

Ted

NT$4,687 total

includes taxes & fees

Dec 14 - Dec 15

A spacious hotel lobby with a reception desk, seating areas, and a view of the dining and kitchen areas.

6. Embassy Suites by Hilton Phoenix Scottsdale

17.8 km from Mayo Clinic Scottsdale

Matthew

NT$4,542 total

includes taxes & fees

Nov 22 - Nov 23

A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

7. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Saad

NT$3,672 total

includes taxes & fees

Dec 14 - Dec 15

An outdoor patio with two sofas facing a stone fire pit, under a pergola with string lights.

8. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Jillian Louise

NT$5,333 total

includes taxes & fees

Dec 14 - Dec 15

A modern hotel with a brick facade, large windows, and a covered entrance area.

9. Springhill Suites Phoenix Scottsdale Marriott

18.2 km from Mayo Clinic Scottsdale

Anna

NT$4,102 total

includes taxes & fees

Nov 22 - Nov 23

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

10. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

Ryan

NT$3,227 total

includes taxes & fees

Dec 14 - Dec 15

A hotel with a clear sky, a sign for 'Spark by Hilton', and a well-maintained lawn.

11. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Herbert M Beatty

NT$3,047 total

includes taxes & fees

Nov 22 - Nov 23

A modern hotel with a flat roof, multiple floors, and a sign indicating 'Springhill Suites'.

12. SpringHill Suites Scottsdale North

13.8 km from Mayo Clinic Scottsdale

John

NT$3,128 total

includes taxes & fees

Nov 22 - Nov 23

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

13. Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Katherine

NT$5,208 total

includes taxes & fees

Nov 22 - Nov 23

A spacious lobby with a large seating area, a reception desk, and artwork on the walls.

14. Best Western Plus Scottsdale Thunderbird Suites

Thunderbird Industrial Airpark, 12.1 km from Mayo Clinic Scottsdale

Irene

NT$3,654 total

includes taxes & fees

Dec 15 - Dec 16

A hotel room with two beds, a TV, a desk, a chair, and a view of palm trees.

15. Hyatt Place Phoenix/Mesa

17.8 km from Mayo Clinic Scottsdale

Laura

NT$3,794 total

includes taxes & fees

Nov 22 - Nov 23

A spacious living area with a kitchen, modern furniture, and a fireplace.

16. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Glen

NT$4,467 total

includes taxes & fees

Nov 29 - Nov 30

An outdoor dining area with tables and chairs, surrounded by trees and a view of a mountain.

17. Mountain Shadows Resort Scottsdale

17 km from Mayo Clinic Scottsdale

karen

NT$9,041 total

includes taxes & fees

Nov 23 - Nov 24

An outdoor seating area with fire pit, red Adirondack chairs, and a covered patio with string lights.

18. Home2 Suites by Hilton Scottsdale North

15 km from Mayo Clinic Scottsdale

Susan

NT$4,109 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor lounge area with white sofas, a fire pit, and a pool in the background.

19. AC Hotel by Marriott Scottsdale North

Paradise Valley Village, 13.4 km from Mayo Clinic Scottsdale

Stan

NT$5,345 total

includes taxes & fees

Nov 28 - Nov 29

A hotel with a curved entrance, a flagpole, and palm trees.

20. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Amy

NT$3,784 total

includes taxes & fees

Nov 22 - Nov 23

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Inn at Eagle Mountain	3.5 star property	9.0 Wonderful 1,042 reviews	View
Sonesta Select Scottsdale at Mayo Clinic Campus	3.0 star property	8.4 Very good 1,080 reviews	View
Talking Stick Resort	4.0 star property	9.4 Exceptional 5,204 reviews	View
Comfort Suites Scottsdale Talking Stick Entertainment District	2.5 star property	9.2 Wonderful 2,075 reviews	View
Hyatt Place Scottsdale - North	3.0 star property	9.4 Exceptional 1,299 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

A bedroom with a bed, a lamp, an air conditioning unit, and curtains.

Starlite Motel

Central Mesa

10/10 Excellent

Virginia

Mountain Shadows Resort Scottsdale

Paradise Valley

10/10 Excellent

Rachael

A modern interior with a sectional sofa, round coffee table, and a seating area with a view of the outside.

The 233 Suites Unscripted by Hyatt

Downtown

10/10 Excellent

Greg

Home2 Suites by Hilton Mesa Longbow, AZ

Falcon Field Area

10/10 Excellent

Alvin

A rooftop terrace with outdoor seating, a fire feature, and a mountain view.

Canopy by Hilton Scottsdale Old Town

Old Town

10/10 Excellent

Shahar

A modern interior with a staircase, a dining area, and a balcony with a tripod.

Hotel Valley Ho

Old Town

10/10 Excellent

Andrew T

An outdoor patio area with a central fire feature, seating arrangements, and a covered walkway.

Residence Inn Scottsdale Salt River

Scottsdale

10/10 Excellent

Maria Robelle

A modern outdoor patio with a fire pit, seating, and a cactus in a landscaped garden.

Courtyard Scottsdale Salt River

Scottsdale

10/10 Excellent

Monica

Hyatt Place Scottsdale - North

Scottsdale

10/10 Excellent

Yoana

Hyatt House North Scottsdale

Scottsdale

10/10 Excellent

Alexander

Comfort Suites Scottsdale Talking Stick Entertainment District

Scottsdale

10/10 Excellent

Darla

A poolside area with a fire feature, seating, and a view of the pool.

Fairfield Inn & Suites by Marriott Tempe

Tempe

10/10 Excellent

I planned a weekend staycation and just wanted a quiet weekend. The price was shockingly great for the location and quality, the reviews and photos sold me and it didn't disappoint. The pool is beautiful. The restaurant in the hotel is pretty good as well, we ordered the Cowboy Burger and the Surf n Turf Burger and both were very good. The hotel was clean, the location is convenient being by Tempe Marketplace so there's plenty to eat and do, and it was overall a great option. I'd absolutely stay...

Krimsun

Inn at Eagle Mountain

Eagle Mountain

10/10 Excellent

carla

A modern kitchen with a microwave, refrigerator, and a coffee maker. There is a dining area with a table and chairs.

Home2 Suites by Hilton Scottsdale Salt River

Scottsdale

10/10 Excellent

Tracy

A resort with multiple buildings, a large pool area, and surrounding mountains.

ADERO Scottsdale Resort, Autograph Collection

Scottsdale

10/10 Excellent

LaKoya

A building with a white brick exterior, large windows, and a variety of cacti and succulents in the surrounding garden area.

Senna House Hotel Scottsdale, Curio Collection by Hilton

Old Town

10/10 Excellent

Vladimira

Frequently Asked Questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,831

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Our top choices for Mayo Clinic Scottsdale hotels

1. Inn at Eagle Mountain

2. Sonesta Select Scottsdale at Mayo Clinic Campus

3. Talking Stick Resort

4. Comfort Suites Scottsdale Talking Stick Entertainment District

5. Hyatt Place Scottsdale - North

6. Embassy Suites by Hilton Phoenix Scottsdale

7. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

8. Home2 Suites by Hilton Mesa Longbow, AZ

9. Springhill Suites Phoenix Scottsdale Marriott

10. Aiden by Best Western Scottsdale North

11. Spark by Hilton Fountain Hills Scottsdale

12. SpringHill Suites Scottsdale North

13. Hyatt House North Scottsdale

14. Best Western Plus Scottsdale Thunderbird Suites

15. Hyatt Place Phoenix/Mesa

16. Fountain Park Hotel, BW Signature Collection

17. Mountain Shadows Resort Scottsdale

18. Home2 Suites by Hilton Scottsdale North

19. AC Hotel by Marriott Scottsdale North

20. Holiday Inn Express Scottsdale North by IHG

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Starlite Motel

10/10 Excellent

Frequently Asked Questions

What's the area like around Mayo Clinic Scottsdale?

What's the best place to stay near Mayo Clinic Scottsdale?

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

What can I see and do near Mayo Clinic Scottsdale?

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