The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A breakfast buffet area with various pastries and a sign indicating the price of a cheese danish.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

Michael

NT$3,409

NT$3,885 total

includes taxes & fees

Oct 8 - Oct 9

A cluster of modern, multi-story buildings with a river in the foreground.

A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

A golf course with a pond, a clubhouse, and a hilly backdrop.

A dining area with a glass table, wooden chairs, and potted plants.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Andrei

NT$3,988

NT$4,553 total

includes taxes & fees

Oct 6 - Oct 7

An outdoor dining table set with chairs, string lights, and a sunset view.

A modern lobby with a seating area, a kitchen, and a reception desk.

A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.

A modern living room with a sectional sofa, orange ottomans, a dining area, and a kitchen with a stone accent wall.

3. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Damon

NT$4,807

NT$5,493 total

includes taxes & fees

Nov 1 - Nov 2

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.

A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

4. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Robert

NT$2,694

NT$3,070 total

includes taxes & fees

Oct 4 - Oct 5

A spacious living area with a kitchen, modern furniture, and a fireplace.

A spacious lobby with a high ceiling, modern chandeliers, a fire feature, and a large TV screen.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

5. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

NT$3,473

NT$3,965 total

includes taxes & fees

Oct 12 - Oct 13

A hotel room with two beds, a TV, a desk, and a window with a view.

A pool area with a clear blue pool, lounge chairs, and a multi-story building with balconies.

A hotel room with two beds, a desk, a TV, and a balcony with a view.

A modern office space with multiple desks, chairs, and a meeting area.

6. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Patricia

NT$2,476

NT$2,827 total

includes taxes & fees

Oct 11 - Oct 12

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A dining area with a large table set for six, surrounded by chairs, with a view of cacti and a stone wall outside.

A golf course with a mountain backdrop, surrounded by desert vegetation.

A lounge area with a grand piano, blue seating, and a stone wall.

7. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Darrick

NT$3,500

NT$5,867 total

includes taxes & fees

Oct 5 - Oct 6

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A bar area with a bar counter, multiple chairs, and a sofa.

A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

8. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

cody

NT$2,719

NT$3,098 total

includes taxes & fees

Oct 4 - Oct 5

A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.

A modern lobby with a brick wall, seating area, and a flat-screen TV.

A restaurant with multiple round tables and bar stools, a self-service beverage dispenser, and a television mounted on the wall.

A modern hotel with a covered entrance, multiple floors, and a parking lot.

9. Hyatt Place Phoenix/Mesa

17.8 km from Mayo Clinic Scottsdale

greg

NT$4,066

NT$4,646 total

includes taxes & fees

Oct 11 - Oct 12

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

A bar area with a long counter, multiple stools, and overhead pendant lighting.

A reception area with marble reception desks, a wooden ceiling, and a wall-mounted refrigerator.

A multi-story hotel with a central courtyard, parking, and a mountainous backdrop.

10. Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Slyqavious

NT$4,301

NT$4,902 total

includes taxes & fees

Oct 28 - Oct 29

A modern kitchen area with a coffee machine, a refrigerator, and a bread display.

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

A modern hotel lobby with a central bar area, seating arrangements, and a clean, contemporary design.

11. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

William

NT$3,313

NT$3,778 total

includes taxes & fees

Oct 11 - Oct 12

A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and a television screen.

A multi-story hotel with a flat roof and balconies, surrounded by well-maintained grass and trees.

An outdoor seating area with a fire feature, surrounded by a fence and palm trees, under a sunset sky.

A bar area with multiple seating options, a bar counter, and a television screen displaying sports.

12. Embassy Suites by Hilton Phoenix Scottsdale

17.8 km from Mayo Clinic Scottsdale

Maria Antoinette

NT$4,938

NT$5,583 total

includes taxes & fees

Oct 12 - Oct 13

An outdoor seating area with fire pit, red Adirondack chairs, and a covered patio with string lights.

A multi-story hotel with a modern design, featuring a prominent 'Home Suites by Hilton' sign.

A modern lounge area with vibrant seating, a central table, and a kitchen area in the background.

A modern hotel room with a dining area, a bed, a desk, and a view of the city.

13. Home2 Suites by Hilton Scottsdale North

15 km from Mayo Clinic Scottsdale

Greta

NT$5,066

NT$5,774 total

includes taxes & fees

Nov 1 - Nov 2

A landscaped garden with a fountain, palm trees, and a building with a red roof.

A courtyard with palm trees, a fountain, and a bench.

A tranquil pond with a fountain, surrounded by lush greenery and a large building in the background.

A modern kitchen with a glass dining table, bar stools, and a built-in island with a microwave and oven.

14. Westgate Painted Mountain Golf Resort

17.4 km from Mayo Clinic Scottsdale

Tammie

NT$3,477

NT$3,974 total

includes taxes & fees

Nov 1 - Nov 2

A resort with multiple buildings, a large pool area, and surrounding mountains.

An outdoor wedding reception with round tables set with white chairs, floral centerpieces, and a view of the city in the background.

A dining area with a table and chairs, a view of a cityscape, and decorative wall panels.

Three people in a swimming pool with rocks and a red umbrella in the background.

15. ADERO Scottsdale Resort, Autograph Collection

3.6 km from Mayo Clinic Scottsdale

Truzanne

NT$7,870

NT$10,258 total

includes taxes & fees

Oct 12 - Oct 13

A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.

A modern kitchen with dark wooden cabinets, a white countertop, and a black refrigerator.

A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows and a covered patio area.

An outdoor patio area with stone pillars, fire pit seating, and tables.

16. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Central Scottsdale, 12.3 km from Mayo Clinic Scottsdale

Dana

NT$5,148

NT$5,867 total

includes taxes & fees

Oct 25 - Oct 26

A circular fire feature with a stone border, surrounded by a landscaped garden with cacti and shrubs, under a sunset sky.

A modern bar area with seating, a digital menu display, and a beverage refrigerator.

A modern lobby with a central water feature, seating area, and a stone pillar.

A pool area with lounge chairs and umbrellas, surrounded by buildings with balconies and outdoor seating.

17. Courtyard Scottsdale Salt River

12.2 km from Mayo Clinic Scottsdale

Karl

NT$4,674

NT$5,327 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with a bed, desk, chair, television, fireplace, and a dining area.

An outdoor patio with a grill, table, and chairs.

A breakfast buffet with various food items and a coffee machine.

A hotel room with a bed, a desk with a TV, a sofa, and a coffee table.

18. Sonesta ES Suites Scottsdale Paradise Valley

14 km from Mayo Clinic Scottsdale

Eriel

NT$4,258

NT$4,853 total

includes taxes & fees

Oct 14 - Oct 15

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

A multi-story hotel with a parking lot and a road leading to a roundabout.

A hotel room with two beds, a desk, a sofa, and a TV.

A bar area with a long counter, multiple bar stools, and overhead lighting.

19. Hyatt Place North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Ana

NT$4,149

NT$4,728 total

includes taxes & fees

Oct 25 - Oct 26

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

20. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Colleen

NT$3,817

NT$4,352 total

includes taxes & fees

Nov 1 - Nov 2

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very good 1,103 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,022 reviews	View
Home2 Suites by Hilton Mesa Longbow, AZ	9.6 Exceptional 908 reviews	View
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale	8.8 Excellent 1,852 reviews	View
Fountain Park Hotel, BW Signature Collection	9.0 Wonderful 1,001 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Aiden by Best Western Scottsdale North

10/10 Excellent

"."

Comfort Suites Scottsdale Talking Stick Entertainment District

8/10 Good

"Rooms are nice restaurants and casinos are nearby I would stay here again."

Home2 Suites by Hilton Scottsdale Salt River

10/10 Excellent

"Conveniently located to the aquarium and not terribly far from many restaurant options"

Great Wolf Lodge Arizona

8/10 Good

"Nice"

Talking Stick Resort

10/10 Excellent

"The room was neat and tidy. The view is beautiful. It was my first time flying to Phoenix. The casino had many slots to choose from. Will be visiting again."

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

10/10 Excellent

"Employees were great! Also excellent location"

ADERO Scottsdale Resort, Autograph Collection

10/10 Excellent

"Great rooms and hotel, staff very helpful at all times and the relaxation was perfect."

Fountain Park Hotel, BW Signature Collection

10/10 Excellent

"We will return to this hotel."

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,827

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Treat yourself

Be picky

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. Home2 Suites by Hilton Mesa Longbow, AZ

4. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

5. Fountain Park Hotel, BW Signature Collection

6. Spark by Hilton Fountain Hills Scottsdale

7. Wekopa Casino Resort

8. Aiden by Best Western Scottsdale North

9. Hyatt Place Phoenix/Mesa

10. Hyatt House North Scottsdale

11. Comfort Suites Scottsdale Talking Stick Entertainment District

12. Embassy Suites by Hilton Phoenix Scottsdale

13. Home2 Suites by Hilton Scottsdale North

14. Westgate Painted Mountain Golf Resort

15. ADERO Scottsdale Resort, Autograph Collection

16. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

17. Courtyard Scottsdale Salt River

18. Sonesta ES Suites Scottsdale Paradise Valley

19. Hyatt Place North Scottsdale

20. Tru By Hilton Scottsdale Salt River

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Aiden by Best Western Scottsdale North

Comfort Suites Scottsdale Talking Stick Entertainment District

Home2 Suites by Hilton Scottsdale Salt River

Great Wolf Lodge Arizona

Talking Stick Resort

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

ADERO Scottsdale Resort, Autograph Collection

Fountain Park Hotel, BW Signature Collection

Frequently asked questions

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