The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

Teri

NT$2,132

NT$2,430 total

includes taxes & fees

Sep 4 - Sep 5

A cluster of modern, multi-story buildings with a river in the foreground.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

A golf course with a pond, a clubhouse, and a hilly backdrop.

A dining area with a glass table, wooden chairs, and potted plants.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Lucia

NT$2,814

NT$3,213 total

includes taxes & fees

Aug 31 - Sep 1

A hotel room with two beds, a TV, a desk, and a window with a view.

A pool area with a clear blue pool, lounge chairs, and a multi-story building with balconies.

A modern office space with multiple desks, chairs, and a meeting area.

A modern hotel room with a large window, a desk with a lamp, a microwave, and a chair.

3. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Jim

NT$2,062

NT$2,354 total

includes taxes & fees

Sep 2 - Sep 3

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.

A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

A bar area with a bar counter, multiple chairs, and a sofa.

4. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

cody

NT$2,501

NT$2,851 total

includes taxes & fees

Aug 30 - Aug 31

A spacious living area with a kitchen, modern furniture, and a fireplace.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

A spacious lobby with a high ceiling, modern chandeliers, a fire feature, and a large TV screen.

5. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Emily

NT$2,673

NT$3,052 total

includes taxes & fees

Aug 30 - Aug 31

A circular fire feature with a stone border, surrounded by a landscaped garden with cacti and shrubs, under a sunset sky.

A pool area with lounge chairs and umbrellas, surrounded by buildings with balconies and outdoor seating.

A modern lobby with a central water feature, seating area, and a stone pillar.

A Courtyard by Marriott hotel with a modern design, featuring a covered entrance and stone pillars.

6. Courtyard Scottsdale Salt River

12.2 km from Mayo Clinic Scottsdale

Karl

NT$2,578

NT$2,938 total

includes taxes & fees

Sep 3 - Sep 4

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

A lounge area with a grand piano, blue seating, and a stone wall.

A golf course with a mountain backdrop, surrounded by desert vegetation.

7. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Kim

NT$3,763

NT$6,164 total

includes taxes & fees

Aug 31 - Sep 1

A well-maintained courtyard with a gazebo, palm trees, and a pathway leading to a building with a grey facade.

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

8. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Caroline

NT$2,119

NT$2,416 total

includes taxes & fees

Sep 6 - Sep 7

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

A hotel room with two beds, a desk, a sofa, and a TV.

A multi-story hotel with a parking lot and a road leading to a roundabout.

A spacious living area with a sofa, armchairs, and a coffee table. There is a TV mounted on the wall and a balcony with outdoor seating.

9. Hyatt Place North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Derrick

NT$2,346

NT$2,674 total

includes taxes & fees

Sep 3 - Sep 4

An outdoor dining table set with chairs, string lights, and a sunset view.

A modern lobby with a seating area, a kitchen, and a reception desk.

A multi-story hotel with a prominent entrance, large windows, and a well-lit facade.

A modern living room with a sectional sofa, orange ottomans, a dining area, and a kitchen with a stone accent wall.

10. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Marie

NT$3,079

NT$3,519 total

includes taxes & fees

Aug 31 - Sep 1

A modern infinity pool with a view of mountains and a sunset.

A poolside lounge with a view of a hotel building, a TV, and a bar area with a bottle of champagne.

A restaurant with high tables and booths, floral wall decorations, and a view of the mountains.

A modern bar area with a unique ceiling design, a bar counter with multiple screens, and a patterned carpet.

11. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Daryl

NT$4,227

NT$5,729 total

includes taxes & fees

Sep 7 - Sep 8

A resort with multiple buildings, a large pool area, and surrounding mountains.

A dining area with a table set for six, overlooking a scenic landscape.

A dining area with a table and chairs, a view of a cityscape, and decorative wall panels.

An outdoor wedding reception with round tables set with white chairs, floral centerpieces, and a view of the city in the background.

12. ADERO Scottsdale Resort, Autograph Collection

3.6 km from Mayo Clinic Scottsdale

Kristen

NT$4,201

NT$6,068 total

includes taxes & fees

Aug 30 - Aug 31

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.

13. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Andrea

NT$2,453

NT$2,797 total

includes taxes & fees

Sep 6 - Sep 7

A hotel room with a sofa, a chair, a desk with a television, a lamp, and a framed artwork on the wall.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a landscaped entrance area with palm trees and shrubs.

A swimming pool with a bridge structure, surrounded by buildings with outdoor seating and a clear sky.

14. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Christiaan Leonard

NT$2,801

NT$3,192 total

includes taxes & fees

Sep 6 - Sep 7

A spacious dining area with multiple tables and chairs, large windows, and a television mounted on the wall.

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

15. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

Cecilia

NT$2,358

NT$2,689 total

includes taxes & fees

Aug 30 - Aug 31

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

A spacious living area with a sofa, chairs, a coffee table, and a TV mounted on the wall.

A bar area with a long counter, multiple stools, and overhead pendant lighting.

A multi-story hotel with a central courtyard, parking, and a mountainous backdrop.

16. Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Christopher

NT$2,673

NT$3,047 total

includes taxes & fees

Aug 30 - Aug 31

A hotel room with a bed, desk, television, fireplace, and seating area.

A breakfast buffet with various food items and a coffee machine.

A hotel room with a bed, a desk, a TV, a sofa, and a chair.

A reception area with a counter, two armchairs, and a round table.

17. Sonesta ES Suites Scottsdale Paradise Valley

14 km from Mayo Clinic Scottsdale

Jonathan

NT$2,260

NT$2,575 total

includes taxes & fees

Sep 6 - Sep 7

A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.

A Hampton Inn & Suites with a stone facade, a welcoming entrance, and a clear sky at dusk.

An outdoor patio area with stone pillars, fire pit seating, and tables.

A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows and a covered patio area.

18. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Central Scottsdale, 12.3 km from Mayo Clinic Scottsdale

Dana

NT$3,105

NT$3,539 total

includes taxes & fees

Sep 2 - Sep 3

A hotel room with a desk, a bed, a TV, a sofa, a small table, and a view of the outdoors.

An outdoor patio area with round tables and chairs, a pool in the background, and a covered seating area.

A multi-story hotel with a modern design, featuring a prominent entrance and a parking lot in front.

A hotel pool area with multiple lounge chairs and a hot tub.

19. Staybridge Suites Scottsdale - Talking Stick by IHG

9.7 km from Mayo Clinic Scottsdale

Eric

NT$3,490

NT$3,979 total

includes taxes & fees

Aug 28 - Aug 29

A hotel pool area with sun loungers, a children's play area, and a building with a sign.

A hotel room with a bed, a green sofa, a TV, a desk, and a green carpet.

An outdoor patio area with round tables and white wicker chairs, red umbrellas, and potted plants.

20. Home2 Suites by Hilton Scottsdale Salt River

9.6 km from Mayo Clinic Scottsdale

Alfredo

NT$2,583

NT$2,946 total

includes taxes & fees

Sep 6 - Sep 7

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very Good 1,116 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,006 reviews	View
Spark by Hilton Fountain Hills Scottsdale	8.8 Excellent 307 reviews	View
Aiden by Best Western Scottsdale North	9.0 Wonderful 1,146 reviews	View
Fountain Park Hotel, BW Signature Collection	9.0 Wonderful 1,001 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Fountain Park Hotel, BW Signature Collection

10/10 Excellent

"Clean comfortable rooms, plenty of place s and things to do in walking distance, right across from fountain park"

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

8/10 Good

"Clean room. Nice staff. Missed breakfast and too hot for pool. Would return."

ADERO Scottsdale Resort, Autograph Collection

10/10 Excellent

"Great place to get away"

Home2 Suites by Hilton Scottsdale Salt River

8/10 Good

"Breakfast wasn't best. Eggs & sausage cold."

Sonesta Select Scottsdale at Mayo Clinic Campus

10/10 Excellent

"Clean room friendly staff breakfast all super!"

Comfort Suites Scottsdale Talking Stick Entertainment District

8/10 Good

"Rooms were clean and roomy, I would stay here again"

Talking Stick Resort

10/10 Excellent

"I enjoyed the layout and cleanliness of the property as well as the room. The room was beautiful and very large."

Wekopa Casino Resort

8/10 Good

"I was surprised that they had vouchers for breakfast."

Tru By Hilton Scottsdale Salt River

10/10 Excellent

"The hotel is clean and the hospitality is excellent. I loved the breakfast option and the entire ambience of the place. Highly recommend."

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 24 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 24 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, McDowell Mountain Golf Club, or Golf Club at Eagle Mountain are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,354

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. Spark by Hilton Fountain Hills Scottsdale

4. Aiden by Best Western Scottsdale North

5. Fountain Park Hotel, BW Signature Collection

6. Courtyard Scottsdale Salt River

7. Wekopa Casino Resort

8. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

9. Hyatt Place North Scottsdale

10. Home2 Suites by Hilton Mesa Longbow, AZ

11. Talking Stick Resort

12. ADERO Scottsdale Resort, Autograph Collection

13. Tru By Hilton Scottsdale Salt River

14. Holiday Inn & Suites Scottsdale North - Airpark by IHG

15. Comfort Suites Scottsdale Talking Stick Entertainment District

16. Hyatt House North Scottsdale

17. Sonesta ES Suites Scottsdale Paradise Valley

18. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

19. Staybridge Suites Scottsdale - Talking Stick by IHG

20. Home2 Suites by Hilton Scottsdale Salt River

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Fountain Park Hotel, BW Signature Collection

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

ADERO Scottsdale Resort, Autograph Collection

Home2 Suites by Hilton Scottsdale Salt River

Sonesta Select Scottsdale at Mayo Clinic Campus

Comfort Suites Scottsdale Talking Stick Entertainment District

Talking Stick Resort

Wekopa Casino Resort

Tru By Hilton Scottsdale Salt River

Frequently asked questions

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