The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

A breakfast buffet area with various pastries and a sign indicating the price of a cheese danish.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

Michael

NT$2,508

NT$2,858 total

includes taxes & fees

Oct 1 - Oct 2

A cluster of modern, multi-story buildings with a river in the foreground.

A dining area with a glass table, wooden chairs, and potted plants.

A golf course with a pond, a clubhouse, and a hilly backdrop.

A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Andrei

NT$3,575

NT$4,082 total

includes taxes & fees

Sep 27 - Sep 28

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Cathleen

NT$2,538

NT$2,892 total

includes taxes & fees

Sep 27 - Sep 28

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

A Comfort Suites hotel with a modern design, featuring a prominent entrance and a covered parking area.

4. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

William

NT$2,741

NT$3,125 total

includes taxes & fees

Sep 29 - Sep 30

A spacious living area with a kitchen, modern furniture, and a fireplace.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

A spacious lobby with a high ceiling, modern chandeliers, a fire feature, and a large TV screen.

A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.

5. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

NT$2,982

NT$3,404 total

includes taxes & fees

Sep 27 - Sep 28

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A lounge area with a grand piano, blue seating, and a stone wall.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

A dining area with a large table set for six, surrounded by chairs, with a view of cacti and a stone wall outside.

6. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Kim

NT$4,021

NT$6,453 total

includes taxes & fees

Sep 27 - Sep 28

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

A bar area with a bar counter, multiple chairs, and a sofa.

7. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

cody

NT$2,732

NT$3,113 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with two beds, a TV, a desk, and a window with a view.

A pool area with a clear blue pool, lounge chairs, and a multi-story building with balconies.

A modern hotel room with a large window, a desk with a lamp, a microwave, and a chair.

A hotel room with two beds, a desk, a TV, and a balcony with a view.

8. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Peyton

NT$2,445

NT$2,792 total

includes taxes & fees

Sep 30 - Oct 1

An outdoor dining table set with chairs, string lights, and a sunset view.

A modern living room with a sectional sofa, orange ottomans, a dining area, and a kitchen with a stone accent wall.

A modern lobby with a seating area, a kitchen, and a reception desk.

A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.

9. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Damon

NT$3,798

NT$4,340 total

includes taxes & fees

Sep 27 - Sep 28

A modern infinity pool with a view of mountains and a sunset.

A poolside lounge with a view of a hotel building, a TV, and a bar area with a bottle of champagne.

An outdoor seating area with fire pits and lounge chairs, surrounded by trees and a building with illuminated windows in the background.

A restaurant with high tables and booths, floral wall decorations, and a view of the mountains.

10. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Meghan Rebbecca

NT$7,031

NT$8,921 total

includes taxes & fees

Sep 27 - Sep 28

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.

11. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Colleen

NT$3,095

NT$3,529 total

includes taxes & fees

Sep 29 - Sep 30

A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.

A hotel breakfast area with a self-serve station, seating, and a trash bin.

A swimming pool with lounge chairs and umbrellas, surrounded by a fence and palm trees.

A hotel room with a desk, chair, television, lamp, and a framed artwork on the wall.

12. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Melanie

NT$2,633

NT$3,001 total

includes taxes & fees

Oct 25 - Oct 26

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

A bar area with a long counter, multiple stools, and overhead pendant lighting.

A reception area with marble reception desks, a wooden ceiling, and a wall-mounted refrigerator.

A spacious living area with a sofa, chairs, a coffee table, and a TV mounted on the wall.

13. Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Slyqavious

NT$3,832

NT$4,367 total

includes taxes & fees

Sep 27 - Sep 28

A resort with multiple buildings, a large pool area, and surrounding mountains.

An outdoor wedding reception with round tables set with white chairs, floral centerpieces, and a view of the city in the background.

A dining area with a table set for six, overlooking a scenic landscape.

A dining area with a table and chairs, a view of a cityscape, and decorative wall panels.

14. ADERO Scottsdale Resort, Autograph Collection

3.6 km from Mayo Clinic Scottsdale

Karen

NT$7,360

NT$9,670 total

includes taxes & fees

Oct 1 - Oct 2

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

A multi-story hotel with a parking lot and a road leading to a roundabout.

A spacious living area with a sofa, armchairs, and a coffee table. There is a TV mounted on the wall and a balcony with outdoor seating.

A hotel room with two beds, a desk, a sofa, and a TV.

15. Hyatt Place North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Gregory

NT$3,071

NT$3,500 total

includes taxes & fees

Sep 30 - Oct 1

An outdoor patio area with round tables and chairs, a pool in the background, and a covered seating area.

A hotel room with a desk, a bed, a TV, a sofa, a small table, and a view of the outdoors.

A hotel room with a bed, a desk, a chair, a sofa, a small table, and a TV.

A multi-story hotel with illuminated signage reading "Talking Stick" and "Resort".

16. Staybridge Suites Scottsdale - Talking Stick by IHG

9.7 km from Mayo Clinic Scottsdale

Yer Suzanne

NT$4,018

NT$4,581 total

includes taxes & fees

Sep 25 - Sep 26

A hotel dining area with a table and chairs, patterned curtains, and a view through large windows.

A golf course with sand bunkers, a flagstick, and mountains in the background.

A hotel room with a large window, a desk, a bed, a TV, and a chair.

A building entrance with a stone facade, large glass doors, and potted plants.

17. Hampton Inn & Suites Scottsdale at Talking Stick

9.1 km from Mayo Clinic Scottsdale

Michelle

NT$3,181

NT$3,627 total

includes taxes & fees

Sep 27 - Sep 28

A breakfast bar with a variety of baked goods and a sign indicating fresh baked items.

A hotel room with a sofa, a chair, a desk with a television, a lamp, and a framed artwork on the wall.

A reception area with a blue counter, a television screen, and a modern interior design.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.

18. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Christiaan Leonard

NT$3,616

NT$4,122 total

includes taxes & fees

Sep 27 - Sep 28

A hotel pool area with sun loungers, a children's play area, and a building with a sign.

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

A hotel room with a bed, a green sofa, a TV, a desk, and a green carpet.

An outdoor patio area with round tables and white wicker chairs, red umbrellas, and potted plants.

19. Home2 Suites by Hilton Scottsdale Salt River

9.6 km from Mayo Clinic Scottsdale

Kate

NT$3,434

NT$3,915 total

includes taxes & fees

Sep 30 - Oct 1

A circular fire feature with a stone border, surrounded by a landscaped garden with cacti and shrubs, under a sunset sky.

A Courtyard by Marriott hotel with a modern design, featuring a covered entrance and stone pillars.

A modern bar area with seating, a digital menu display, and a beverage refrigerator.

A pool area with lounge chairs and umbrellas, surrounded by buildings with balconies and outdoor seating.

20. Courtyard Scottsdale Salt River

12.2 km from Mayo Clinic Scottsdale

Karl

NT$4,631

NT$5,278 total

includes taxes & fees

Oct 1 - Oct 2

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very good 1,099 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,014 reviews	View
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale	8.8 Excellent 1,862 reviews	View
Comfort Suites Scottsdale Talking Stick Entertainment District	9.2 Wonderful 2,026 reviews	View
Fountain Park Hotel, BW Signature Collection	9.0 Wonderful 1,000 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Wekopa Casino Resort

10/10 Excellent

"It was a very nice stay."

Inn at Eagle Mountain

10/10 Excellent

"Everything was clean and nicely organized. Very nice hotel will stay at again."

Fountain Park Hotel, BW Signature Collection

10/10 Excellent

"Great location."

Aiden by Best Western Scottsdale North

10/10 Excellent

"I often stay here for work when I travel to Scottsdale. The stuff is great, and the hotel is nice overall"

ADERO Scottsdale Resort, Autograph Collection

10/10 Excellent

"."

Hilton Vacation Club Scottsdale Links Resort

10/10 Excellent

"GREAT STAY- WE WILL STAY AGAIN"

Great Wolf Lodge Arizona

8/10 Good

"It was an amazing time but had one staff member be a bit rude while buying alcohol clearly paid for special cup and gave me whatever she wanted and still charged me. Didn’t want to make a big deal but other than that it’s was nice clean fun"

Sonesta Select Scottsdale at Mayo Clinic Campus

10/10 Excellent

"The staff was nice, friendly and costumer oriented"

Spark by Hilton Fountain Hills Scottsdale

10/10 Excellent

"This is the cleanest and cheapest hotel I've stayed at in a while. 10/10 would recommend."

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 21 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 21 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,792

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Treat yourself

Be picky

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

4. Comfort Suites Scottsdale Talking Stick Entertainment District

5. Fountain Park Hotel, BW Signature Collection

6. Wekopa Casino Resort

7. Aiden by Best Western Scottsdale North

8. Spark by Hilton Fountain Hills Scottsdale

9. Home2 Suites by Hilton Mesa Longbow, AZ

10. Talking Stick Resort

11. Tru By Hilton Scottsdale Salt River

12. Holiday Inn Express Scottsdale North by IHG

13. Hyatt House North Scottsdale

14. ADERO Scottsdale Resort, Autograph Collection

15. Hyatt Place North Scottsdale

16. Staybridge Suites Scottsdale - Talking Stick by IHG

17. Hampton Inn & Suites Scottsdale at Talking Stick

18. Holiday Inn & Suites Scottsdale North - Airpark by IHG

19. Home2 Suites by Hilton Scottsdale Salt River

20. Courtyard Scottsdale Salt River

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Wekopa Casino Resort

Inn at Eagle Mountain

Fountain Park Hotel, BW Signature Collection

Aiden by Best Western Scottsdale North

ADERO Scottsdale Resort, Autograph Collection

Hilton Vacation Club Scottsdale Links Resort

Great Wolf Lodge Arizona

Sonesta Select Scottsdale at Mayo Clinic Campus

Spark by Hilton Fountain Hills Scottsdale

Frequently asked questions

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