The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

Michael

NT$2,508

NT$2,858 total

includes taxes & fees

Oct 1 - Oct 2

A cluster of modern, multi-story buildings with a river in the foreground.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

A dining area with a glass table, wooden chairs, and potted plants.

A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Andrei

NT$3,575

NT$4,082 total

includes taxes & fees

Sep 28 - Sep 29

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Cathleen

NT$2,292

NT$2,612 total

includes taxes & fees

Sep 27 - Sep 28

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

A Comfort Suites hotel with a modern design, featuring a prominent entrance and a covered parking area.

4. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

William

NT$2,743

NT$3,127 total

includes taxes & fees

Sep 27 - Sep 28

A spacious living area with a kitchen, modern furniture, and a fireplace.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.

5. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

NT$2,982

NT$3,404 total

includes taxes & fees

Sep 28 - Sep 29

A modern kitchen with white cabinets, a built-in oven, and a large window.

An outdoor kitchen with a grill and a built-in oven, surrounded by a brick wall and a tree.

A modern kitchen with dark cabinetry, a wooden island, and pendant lighting.

A covered patio area with a swing set, a slide, and a seating area with benches.

6. Close to Hiking! Family-friendly Mesa Retreat

13.6 km from Mayo Clinic Scottsdale

NT$5,710

NT$24,838 total

includes taxes & fees

Oct 5 - Oct 6

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

A lounge area with a grand piano, blue seating, and a stone wall.

A dining area with a large table set for six, surrounded by chairs, with a view of cacti and a stone wall outside.

7. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Kim

NT$4,021

NT$6,453 total

includes taxes & fees

Sep 27 - Sep 28

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.

8. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

NT$2,732

NT$3,114 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with two beds, a TV, a desk, and a window with a view.

A hotel room with two beds, a desk, a TV, and a balcony with a view.

A modern office space with multiple desks, chairs, and a meeting area.

A pool area with a clear blue pool, lounge chairs, and a multi-story building with balconies.

9. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Peyton

NT$2,445

NT$2,792 total

includes taxes & fees

Oct 1 - Oct 2

A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.

A hotel gym with dumbbells on racks, a bench, and a mirror.

A hotel room with a desk, chair, television, lamp, and a framed artwork on the wall.

A hotel breakfast area with a self-serve station, seating, and a trash bin.

10. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Melanie

NT$2,633

NT$3,001 total

includes taxes & fees

Oct 25 - Oct 26

A modern infinity pool with a view of mountains and a sunset.

An outdoor seating area with fire pits and lounge chairs, surrounded by trees and a building with illuminated windows in the background.

A restaurant with high tables and booths, floral wall decorations, and a view of the mountains.

A modern bar area with a unique ceiling design, a bar counter with multiple screens, and a patterned carpet.

11. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Meghan Rebbecca

NT$6,707

NT$8,552 total

includes taxes & fees

Oct 10 - Oct 11

An outdoor dining table set with chairs, string lights, and a sunset view.

A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.

A modern living room with a sectional sofa, orange ottomans, a dining area, and a kitchen with a stone accent wall.

A modern lobby with a seating area, a kitchen, and a reception desk.

12. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Damon

NT$3,668

NT$4,192 total

includes taxes & fees

Sep 27 - Sep 28

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

13. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Colleen

NT$3,227

NT$3,680 total

includes taxes & fees

Sep 30 - Oct 1

A resort with multiple buildings, a large pool area, and surrounding mountains.

A dining area with a table set for six, overlooking a scenic landscape.

A dining area with a table and chairs, a view of a cityscape, and decorative wall panels.

An outdoor wedding reception with round tables set with white chairs, floral centerpieces, and a view of the city in the background.

14. ADERO Scottsdale Resort, Autograph Collection

3.6 km from Mayo Clinic Scottsdale

Karen

NT$7,360

NT$9,670 total

includes taxes & fees

Oct 1 - Oct 2

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

A hotel room with two beds, a desk, a sofa, and a TV.

A bar area with a long counter, multiple bar stools, and overhead lighting.

A multi-story hotel with a parking lot and a road leading to a roundabout.

15. Hyatt Place North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Gregory

NT$3,071

NT$3,500 total

includes taxes & fees

Sep 30 - Oct 1

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

A spacious living area with a sofa, chairs, a coffee table, and a TV mounted on the wall.

A multi-story hotel with a central courtyard, parking, and a mountainous backdrop.

A bar area with a long counter, multiple stools, and overhead pendant lighting.

16. Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Slyqavious

NT$3,528

NT$4,021 total

includes taxes & fees

Sep 27 - Sep 28

An outdoor patio area with round tables and chairs, a pool in the background, and a covered seating area.

A multi-story hotel with illuminated signage reading "Talking Stick" and "Resort".

A hotel room with a desk, a bed, a TV, a sofa, a small table, and a view of the outdoors.

A hotel room with a bed, a desk, a chair, a sofa, a small table, and a TV.

17. Staybridge Suites Scottsdale - Talking Stick by IHG

9.7 km from Mayo Clinic Scottsdale

Friedemann

NT$4,288

NT$4,889 total

includes taxes & fees

Sep 26 - Sep 27

A hotel dining area with a table and chairs, patterned curtains, and a view through large windows.

A hotel room with a large window, a desk, a bed, a TV, and a chair.

A hotel lobby with a bar area, seating, and a reception desk.

A golf course with sand bunkers, a flagstick, and mountains in the background.

18. Hampton Inn & Suites Scottsdale at Talking Stick

9.1 km from Mayo Clinic Scottsdale

Michelle

NT$3,306

NT$3,770 total

includes taxes & fees

Sep 27 - Sep 28

A breakfast bar with a variety of baked goods and a sign indicating fresh baked items.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.

A reception area with a blue counter, a television screen, and a modern interior design.

A hotel room with a flat-screen TV, a fireplace, a sofa, a coffee table, and a large window with a view.

19. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Christiaan Leonard

NT$4,029

NT$4,592 total

includes taxes & fees

Sep 29 - Sep 30

A circular fire feature with a stone border, surrounded by a landscaped garden with cacti and shrubs, under a sunset sky.

A modern bar area with seating, a digital menu display, and a beverage refrigerator.

A Courtyard by Marriott hotel with a modern design, featuring a covered entrance and stone pillars.

A pool area with lounge chairs and umbrellas, surrounded by buildings with balconies and outdoor seating.

20. Courtyard Scottsdale Salt River

12.2 km from Mayo Clinic Scottsdale

Karl

NT$4,632

NT$5,279 total

includes taxes & fees

Oct 1 - Oct 2

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very good 1,099 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,014 reviews	View
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale	8.8 Excellent 1,854 reviews	View
Comfort Suites Scottsdale Talking Stick Entertainment District	9.2 Wonderful 2,027 reviews	View
Fountain Park Hotel, BW Signature Collection	9.0 Wonderful 1,001 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Wekopa Casino Resort

10/10 Excellent

"It was a very nice stay."

Inn at Eagle Mountain

10/10 Excellent

"Everything was clean and nicely organized. Very nice hotel will stay at again."

Fountain Park Hotel, BW Signature Collection

10/10 Excellent

"Great location."

ADERO Scottsdale Resort, Autograph Collection

10/10 Excellent

"."

Hilton Vacation Club Scottsdale Links Resort

10/10 Excellent

"GREAT STAY- WE WILL STAY AGAIN"

Great Wolf Lodge Arizona

8/10 Good

"It was an amazing time but had one staff member be a bit rude while buying alcohol clearly paid for special cup and gave me whatever she wanted and still charged me. Didn’t want to make a big deal but other than that it’s was nice clean fun"

Sonesta Select Scottsdale at Mayo Clinic Campus

10/10 Excellent

"The staff was nice, friendly and costumer oriented"

Spark by Hilton Fountain Hills Scottsdale

10/10 Excellent

"This is the cleanest and cheapest hotel I've stayed at in a while. 10/10 would recommend."

Sonesta Simply Suites Phoenix Scottsdale

8/10 Good

"I think the room needs some upgrading. It’s a comfortable room size wise and having a full kitchen is convenient. The furniture is old and needs to be upgraded and the rug inside the rooms smelled musty and could use a steam cleaning all in all. It’s still a pretty good value for the area you’re staying in and it’s has a gas station downstairs and is across the street from the Scottsdale, fiesta, which has a multitude of eateries and a supermarket I don’t like that we had to pay five dollars a night for parking"

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 21 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 21 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,612

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Treat yourself

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

4. Comfort Suites Scottsdale Talking Stick Entertainment District

5. Fountain Park Hotel, BW Signature Collection

6. Close to Hiking! Family-friendly Mesa Retreat

7. Wekopa Casino Resort

8. Aiden by Best Western Scottsdale North

9. Spark by Hilton Fountain Hills Scottsdale

10. Holiday Inn Express Scottsdale North by IHG

11. Talking Stick Resort

12. Home2 Suites by Hilton Mesa Longbow, AZ

13. Tru By Hilton Scottsdale Salt River

14. ADERO Scottsdale Resort, Autograph Collection

15. Hyatt Place North Scottsdale

16. Hyatt House North Scottsdale

17. Staybridge Suites Scottsdale - Talking Stick by IHG

18. Hampton Inn & Suites Scottsdale at Talking Stick

19. Holiday Inn & Suites Scottsdale North - Airpark by IHG

20. Courtyard Scottsdale Salt River

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Wekopa Casino Resort

Inn at Eagle Mountain

Fountain Park Hotel, BW Signature Collection

ADERO Scottsdale Resort, Autograph Collection

Hilton Vacation Club Scottsdale Links Resort

Great Wolf Lodge Arizona

Sonesta Select Scottsdale at Mayo Clinic Campus

Spark by Hilton Fountain Hills Scottsdale

Sonesta Simply Suites Phoenix Scottsdale

Frequently asked questions

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