The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

Michael

NT$3,417

NT$3,895 total

includes taxes & fees

Oct 12 - Oct 13

A cluster of modern, multi-story buildings with a river in the foreground.

A dining area with a glass table, wooden chairs, and potted plants.

A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Shelby

NT$4,248

NT$4,850 total

includes taxes & fees

Oct 26 - Oct 27

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Paul

NT$2,688

NT$3,063 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

A modern hotel lobby with a central bar area, seating arrangements, and a clean, contemporary design.

4. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

William

NT$3,478

NT$3,966 total

includes taxes & fees

Oct 25 - Oct 26

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.

A bar area with a bar counter, multiple chairs, and a sofa.

A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

5. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

Ioana G

NT$3,090

NT$3,522 total

includes taxes & fees

Oct 11 - Oct 12

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

A dining area with a large table set for six, surrounded by chairs, with a view of cacti and a stone wall outside.

A golf course with a mountain backdrop, surrounded by desert vegetation.

6. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

jennifer

NT$4,395

NT$6,888 total

includes taxes & fees

Oct 20 - Oct 21

A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.

A hotel room with two beds, a TV, a desk, a chair, and a view of palm trees.

A modern hotel with a covered entrance, multiple floors, and a parking lot.

A modern lobby with a brick wall, seating area, and a flat-screen TV.

7. Hyatt Place Phoenix/Mesa

17.8 km from Mayo Clinic Scottsdale

greg

NT$4,283

NT$4,894 total

includes taxes & fees

Oct 12 - Oct 13

A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and a television screen.

A bar area with multiple seating options, a bar counter, and a television screen displaying sports.

A multi-story hotel with a flat roof and balconies, surrounded by well-maintained grass and trees.

A spacious hotel lobby with a reception desk, seating areas, and a view of the dining and kitchen areas.

8. Embassy Suites by Hilton Phoenix Scottsdale

17.8 km from Mayo Clinic Scottsdale

Maria Antoinette

NT$4,942

NT$5,587 total

includes taxes & fees

Oct 18 - Oct 19

A circular fire feature with a stone border, surrounded by a landscaped garden with cacti and shrubs, under a sunset sky.

A modern bar area with seating, a digital menu display, and a beverage refrigerator.

A pool area with lounge chairs and umbrellas, surrounded by buildings with balconies and outdoor seating.

A modern lobby with a central water feature, seating area, and a stone pillar.

9. Courtyard Scottsdale Salt River

12.2 km from Mayo Clinic Scottsdale

Karl

NT$4,663

NT$5,315 total

includes taxes & fees

Oct 18 - Oct 19

A hotel pool area with sun loungers, a children's play area, and a building with a sign.

An outdoor patio area with round tables and white wicker chairs, red umbrellas, and potted plants.

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

A hotel room with a bed, a green sofa, a TV, a desk, and a green carpet.

10. Home2 Suites by Hilton Scottsdale Salt River

9.6 km from Mayo Clinic Scottsdale

Felipe

NT$4,164

NT$4,748 total

includes taxes & fees

Nov 1 - Nov 2

A spacious living area with a kitchen, modern furniture, and a fireplace.

A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

11. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

NT$3,475

NT$3,968 total

includes taxes & fees

Oct 18 - Oct 19

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.

A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

12. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Colleen

NT$3,638

NT$4,148 total

includes taxes & fees

Nov 8 - Nov 9

A breakfast bar with a variety of baked goods and a sign indicating fresh baked items.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.

A hotel room with a flat-screen TV, a fireplace, a sofa, a coffee table, and a large window with a view.

A hotel room with a sofa, a chair, a desk with a television, a lamp, and a framed artwork on the wall.

13. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Ally Marie

NT$4,823

NT$5,497 total

includes taxes & fees

Nov 8 - Nov 9

A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.

A modern kitchen with dark wooden cabinets, a white countertop, and a black refrigerator.

A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows and a covered patio area.

A Hampton Inn & Suites with a stone facade, a welcoming entrance, and a clear sky at dusk.

14. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Central Scottsdale, 12.3 km from Mayo Clinic Scottsdale

Dana

NT$5,158

NT$5,879 total

includes taxes & fees

Nov 1 - Nov 2

A hotel pool area with lounge chairs, a hot tub, and a building with balconies.

A motel with a prominent '6' sign, a parking lot, and palm trees.

A hotel reception area with a modern design, including a reception desk, a television mounted on the wall, and a large window providing natural light.

A hotel room with a bed, a desk, a chair, and a mirror.

15. Motel 6 Old town Scottsdale/Fashion Square

Fashion Square, 15.9 km from Mayo Clinic Scottsdale

Kayla

NT$2,550

NT$2,907 total

includes taxes & fees

Oct 20 - Oct 21

A modern bar area with a long counter, multiple stools, and large windows offering a view of the outdoor garden.

An outdoor patio area with tables and chairs, surrounded by potted plants and palm trees.

A hotel entrance with a covered area, palm trees, and a signboard.

A hotel lobby with a reception area, seating, and a view of the outdoor garden.

16. Papago Scottsdale by Reside, Trademark Collection by Wyndham

18.4 km from Mayo Clinic Scottsdale

Kat

NT$3,421

NT$3,899 total

includes taxes & fees

Oct 11 - Oct 12

A modern hotel with a brick facade, large windows, and a covered entrance area.

A modern lobby with a sectional sofa, a round coffee table, and a mural on the wall.

A hotel room with a desk, two beds, a TV, and a large window.

An outdoor patio area with round tables and chairs, a fire pit, and a large umbrella.

17. Springhill Suites Phoenix Scottsdale Marriott

18.2 km from Mayo Clinic Scottsdale

Marie

NT$3,784

NT$4,313 total

includes taxes & fees

Oct 18 - Oct 19

A hotel dining area with a table and chairs, patterned curtains, and a view through large windows.

A hotel lobby with a bar area, seating, and a reception desk.

A hotel room with a large window, a desk, a bed, a TV, and a chair.

A golf course with sand bunkers, a flagstick, and mountains in the background.

18. Hampton Inn & Suites Scottsdale at Talking Stick

9.1 km from Mayo Clinic Scottsdale

Mark

NT$3,556

NT$4,055 total

includes taxes & fees

Nov 8 - Nov 9

An outdoor lounge area with white sofas, a fire pit, and a pool in the background.

A modern hotel lobby with a long seating area, a reception desk, and large windows providing natural light.

A modern outdoor lounge area with white furniture, a pool, and large umbrellas.

A spacious hotel lobby with modern furniture, large windows, and a flat-screen TV.

19. AC Hotel by Marriott Scottsdale North

Paradise Valley Village, 13.4 km from Mayo Clinic Scottsdale

Kristen

NT$6,900

NT$7,802 total

includes taxes & fees

Oct 23 - Oct 24

An outdoor dining table set with chairs, string lights, and a sunset view.

A modern living room with a sectional sofa, orange ottomans, a dining area, and a kitchen with a stone accent wall.

A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.

A modern lobby with a seating area, a kitchen, and a reception desk.

20. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Damon

NT$4,995

NT$5,708 total

includes taxes & fees

Nov 1 - Nov 2

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very good 1,089 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,026 reviews	View
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale	8.8 Excellent 1,855 reviews	View
Comfort Suites Scottsdale Talking Stick Entertainment District	9.2 Wonderful 2,041 reviews	View
Aiden by Best Western Scottsdale North	9.0 Wonderful 1,174 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

10/10 Excellent

"The room was clean with all amenities, staff was pleasant and helpful. We had a problem with "no signal" on the TV but was quickly attended to. Breakfast was standard, eggs, sausage, waffles etc. No potatoes but the coffee was good! Good restaurants near by as well as Sprouts. We enjoyed our stay at this La Quinta."

Talking Stick Resort

10/10 Excellent

"Loved the amenities in the room - bottled water, variety of tea & coffees with creamers. My husband especially enjoyed that there was a large shower while I enjoyed the lovely bathtub."

Aiden by Best Western Scottsdale North

10/10 Excellent

"Bien ubicado, agradable el hotel y el vecindario, muy limpias y amplias las habitaciones. Mi única sugerencia es que el desayuno puede mejorar ya que lo cobran a elección del huésped, creo que puede ser de mejor calidad."

Inn at Eagle Mountain

10/10 Excellent

"Wonderful staff!!"

Home2 Suites by Hilton Scottsdale Salt River

8/10 Good

"Family trip with toddler and teen. Breakfast was delicious, room was great and spacious."

ADERO Scottsdale Resort, Autograph Collection

10/10 Excellent

"Our stay was wonderful. A few high points: - The staff were friendly and helpful. Jasmine, for one, at the front desk was very responsive. - Dom and Keri in the spa were especially wonderful (as was our masseuse). Can't wait to come back to the spa (hopefully next year?). Lots of great services available there. - Housekeeping was efficient and did a great job. - The resort was beautiful and quiet with a terrific view. Perfect for what our needs were. - The surrounding community, while not walkable, has plenty of restaurants and shopping close by (check out Fountain Hills, it's a nice alternative to Scottsdale, the fountain is cool!). I hope we can go back again (I really didn't want to leave!)."

Sonesta Select Scottsdale at Mayo Clinic Campus

10/10 Excellent

"I had a quiet stay which allowed me to rest well and appreciated the cool pool"

Spark by Hilton Fountain Hills Scottsdale

10/10 Excellent

"It was a comfortable stay."

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,907

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

4. Comfort Suites Scottsdale Talking Stick Entertainment District

5. Aiden by Best Western Scottsdale North

6. Wekopa Casino Resort

7. Hyatt Place Phoenix/Mesa

8. Embassy Suites by Hilton Phoenix Scottsdale

9. Courtyard Scottsdale Salt River

10. Home2 Suites by Hilton Scottsdale Salt River

11. Fountain Park Hotel, BW Signature Collection

12. Tru By Hilton Scottsdale Salt River

13. Holiday Inn & Suites Scottsdale North - Airpark by IHG

14. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

15. Motel 6 Old town Scottsdale/Fashion Square

16. Papago Scottsdale by Reside, Trademark Collection by Wyndham

17. Springhill Suites Phoenix Scottsdale Marriott

18. Hampton Inn & Suites Scottsdale at Talking Stick

19. AC Hotel by Marriott Scottsdale North

20. Home2 Suites by Hilton Mesa Longbow, AZ

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Talking Stick Resort

Aiden by Best Western Scottsdale North

Inn at Eagle Mountain

Home2 Suites by Hilton Scottsdale Salt River

ADERO Scottsdale Resort, Autograph Collection

Sonesta Select Scottsdale at Mayo Clinic Campus

Spark by Hilton Fountain Hills Scottsdale

Frequently asked questions

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