The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

A breakfast buffet area with various pastries and a sign indicating the price of a cheese danish.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

Teri

NT$2,521

NT$2,873 total

includes taxes & fees

Sep 14 - Sep 15

A cluster of modern, multi-story buildings with a river in the foreground.

A dining area with a glass table, wooden chairs, and potted plants.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

A golf course with a pond, a clubhouse, and a hilly backdrop.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Elizabeth

NT$3,533

NT$4,033 total

includes taxes & fees

Sep 10 - Sep 11

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Steven

NT$2,101

NT$2,395 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with two beds, a TV, a desk, and a window with a view.

A modern office space with multiple desks, chairs, and a meeting area.

A hotel room with two beds, a desk, a TV, and a balcony with a view.

A pool area with a clear blue pool, lounge chairs, and a multi-story building with balconies.

4. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Jim

NT$1,914

NT$2,186 total

includes taxes & fees

Sep 15 - Sep 16

A spacious living area with a kitchen, modern furniture, and a fireplace.

A spacious lobby with a high ceiling, modern chandeliers, a fire feature, and a large TV screen.

A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

5. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

NT$2,647

NT$3,022 total

includes taxes & fees

Sep 10 - Sep 11

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

A Comfort Suites hotel with a modern design, featuring a covered entrance and a parking lot.

6. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

Brenda

NT$2,488

NT$2,837 total

includes taxes & fees

Sep 13 - Sep 14

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.

7. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

cody

NT$2,353

NT$2,681 total

includes taxes & fees

Sep 10 - Sep 11

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

A lounge area with a grand piano, blue seating, and a stone wall.

A dining area with a large table set for six, surrounded by chairs, with a view of cacti and a stone wall outside.

8. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Kim

NT$4,121

NT$6,554 total

includes taxes & fees

Sep 14 - Sep 15

An outdoor dining table set with chairs, string lights, and a sunset view.

A modern lobby with a seating area, a kitchen, and a reception desk.

A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.

A multi-story hotel with a prominent entrance, large windows, and a well-lit facade.

9. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Marie

NT$3,751

NT$4,286 total

includes taxes & fees

Sep 13 - Sep 14

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

10. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Andrea

NT$2,728

NT$3,111 total

includes taxes & fees

Sep 13 - Sep 14

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

A hotel room with two beds, a desk, a sofa, and a TV.

A multi-story hotel with a parking lot and a road leading to a roundabout.

A spacious living area with a sofa, armchairs, and a coffee table. There is a TV mounted on the wall and a balcony with outdoor seating.

11. Hyatt Place North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Jamie A.

NT$2,874

NT$3,276 total

includes taxes & fees

Sep 20 - Sep 21

A hotel dining area with a table and chairs, patterned curtains, and a view through large windows.

A golf course with sand bunkers, a flagstick, and mountains in the background.

A hotel room with a large window, a desk, a bed, a TV, and a chair.

A building entrance with a stone facade, large glass doors, and potted plants.

12. Hampton Inn & Suites Scottsdale at Talking Stick

9.1 km from Mayo Clinic Scottsdale

Michelle

NT$2,831

NT$3,228 total

includes taxes & fees

Sep 20 - Sep 21

A hotel room with a bed, desk, television, fireplace, and seating area.

An outdoor patio with a grill, table, and chairs.

A hotel room with a bed, a desk with a TV, a sofa, and a coffee table.

A breakfast buffet with various food items and a coffee machine.

13. Sonesta ES Suites Scottsdale Paradise Valley

14 km from Mayo Clinic Scottsdale

Oluwaseun

NT$2,745

NT$3,128 total

includes taxes & fees

Sep 15 - Sep 16

A modern infinity pool with a view of mountains and a sunset.

A restaurant with high tables and booths, floral wall decorations, and a view of the mountains.

An outdoor seating area with fire pits and lounge chairs, surrounded by trees and a building with illuminated windows in the background.

A poolside lounge with a view of a hotel building, a TV, and a bar area with a bottle of champagne.

14. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Daniel

NT$5,588

NT$7,270 total

includes taxes & fees

Sep 10 - Sep 11

A circular fire feature with a stone border, surrounded by a landscaped garden with cacti and shrubs, under a sunset sky.

A modern lobby with a central water feature, seating area, and a stone pillar.

A Courtyard by Marriott hotel with a modern design, featuring a covered entrance and stone pillars.

A pool area with lounge chairs and umbrellas, surrounded by buildings with balconies and outdoor seating.

15. Courtyard Scottsdale Salt River

12.2 km from Mayo Clinic Scottsdale

Karl

NT$3,435

NT$3,915 total

includes taxes & fees

Sep 10 - Sep 11

A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.

A swimming pool with lounge chairs and umbrellas, surrounded by a fence and palm trees.

A hotel breakfast area with a self-serve station, seating, and a trash bin.

A hotel room with a desk, chair, television, lamp, and a framed artwork on the wall.

16. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Linnette

NT$2,458

NT$2,802 total

includes taxes & fees

Sep 12 - Sep 13

A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.

A Hampton Inn & Suites with a stone facade, a welcoming entrance, and a clear sky at dusk.

An outdoor patio area with stone pillars, fire pit seating, and tables.

A modern kitchen with dark wooden cabinets, a white countertop, and a black refrigerator.

17. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Central Scottsdale, 12.3 km from Mayo Clinic Scottsdale

Dana

NT$3,674

NT$4,187 total

includes taxes & fees

Sep 14 - Sep 15

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

A bar area with a long counter, multiple stools, and overhead pendant lighting.

A reception area with marble reception desks, a wooden ceiling, and a wall-mounted refrigerator.

A spacious living area with a sofa, chairs, a coffee table, and a TV mounted on the wall.

18. Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Javier Alejandro

NT$3,505

NT$3,994 total

includes taxes & fees

Sep 20 - Sep 21

A hotel pool area with sun loungers, a children's play area, and a building with a sign.

A modern kitchen with a central island, bar stools, and a sign that reads "inspired table".

An outdoor patio area with round tables and white wicker chairs, red umbrellas, and potted plants.

19. Home2 Suites by Hilton Scottsdale Salt River

9.6 km from Mayo Clinic Scottsdale

Kate

NT$2,873

NT$3,276 total

includes taxes & fees

Sep 13 - Sep 14

An outdoor patio with a fire pit, string lights, and outdoor furniture.

A swimming pool with lounge chairs and umbrellas, surrounded by a building with a covered area and mountains in the background.

A residential building with multiple balconies, a well-maintained lawn, and a clear sky.

A well-maintained outdoor area with a playground, a covered seating area, and a variety of landscaped plants.

20. Hilton Vacation Club Scottsdale Links Resort

11.3 km from Mayo Clinic Scottsdale

Kathy

NT$3,000

NT$4,354 total

includes taxes & fees

Sep 16 - Sep 17

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very Good 1,106 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,009 reviews	View
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale	8.8 Excellent 1,862 reviews	View
Spark by Hilton Fountain Hills Scottsdale	8.8 Excellent 310 reviews	View
Fountain Park Hotel, BW Signature Collection	9.0 Wonderful 1,000 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Talking Stick Resort

10/10 Excellent

"Great location. The pool area was excellent and summer is the beat time for rates and less people"

Inn at Eagle Mountain

8/10 Good

"It was great"

Staybridge Suites Scottsdale - Talking Stick by IHG

10/10 Excellent

"This Hotel surprised us. It was wonderful. The breakfast was much better than much more expensive Hotels. Also my wife said to say that the pillows were excellent and that she usually brings her own pillow but no need here as they were perfect. We will be back as it is very close to many fun things to do in Scottsdale like the Odysea Aquarium that we visited and loved."

Sonesta Simply Suites Phoenix Scottsdale

10/10 Excellent

"It close to where I need to go and very friendly day staff the rooms r always clean"

Comfort Suites Scottsdale Talking Stick Entertainment District

8/10 Good

"Clean room, friendly staff, great breakfast! A few pool deck tiles were loose and could lead to a stubbed toe, but the pool was clean towels were stocked. Great place in a great location."

Tru By Hilton Scottsdale Salt River

8/10 Good

"It was a nice hotel and for the most part the staff was friendly. The only one thing is that they didn't replenish our toilet paper nor did they clean the room and we were there for 3 nights, other than that we had a good stay."

Home2 Suites by Hilton Scottsdale Salt River

10/10 Excellent

"Wonderful place to stay with family. We were able to play games on site with their huge connect four and pool table. They also had games upon request. Room, Pool, Sauna, Gym were all great and staffed with all necessities. Awesome staff everywhere!"

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

8/10 Good

"👍"

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 20 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 20 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, SunRidge Canyon Golf Club, or McDowell Mountain Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,186

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Treat yourself

Be picky

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

4. Spark by Hilton Fountain Hills Scottsdale

5. Fountain Park Hotel, BW Signature Collection

6. Comfort Suites Scottsdale Talking Stick Entertainment District

7. Aiden by Best Western Scottsdale North

8. Wekopa Casino Resort

9. Home2 Suites by Hilton Mesa Longbow, AZ

10. Tru By Hilton Scottsdale Salt River

11. Hyatt Place North Scottsdale

12. Hampton Inn & Suites Scottsdale at Talking Stick

13. Sonesta ES Suites Scottsdale Paradise Valley

14. Talking Stick Resort

15. Courtyard Scottsdale Salt River

16. Holiday Inn Express Scottsdale North by IHG

17. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

18. Hyatt House North Scottsdale

19. Home2 Suites by Hilton Scottsdale Salt River

20. Hilton Vacation Club Scottsdale Links Resort

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Talking Stick Resort

Inn at Eagle Mountain

Staybridge Suites Scottsdale - Talking Stick by IHG

Sonesta Simply Suites Phoenix Scottsdale

Comfort Suites Scottsdale Talking Stick Entertainment District

Tru By Hilton Scottsdale Salt River

Home2 Suites by Hilton Scottsdale Salt River

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Frequently asked questions

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