The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

Michael

NT$3,467

NT$3,951 total

includes taxes & fees

Oct 21 - Oct 22

A cluster of modern, multi-story buildings with a river in the foreground.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

A golf course with a pond, a clubhouse, and a hilly backdrop.

A dining area with a glass table, wooden chairs, and potted plants.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Stephanie

NT$4,171

NT$4,762 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

A modern hotel lobby with a central bar area, seating arrangements, and a clean, contemporary design.

3. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

LAURA

NT$3,528

NT$4,023 total

includes taxes & fees

Nov 1 - Nov 2

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.

4. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Wilson

NT$2,727

NT$3,108 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor dining table set with chairs, string lights, and a sunset view.

A modern living room with a sectional sofa, orange ottomans, a dining area, and a kitchen with a stone accent wall.

A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.

A modern lobby with a seating area, a kitchen, and a reception desk.

5. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Damon

NT$5,012

NT$5,728 total

includes taxes & fees

Nov 1 - Nov 2

A spacious living area with a kitchen, modern furniture, and a fireplace.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

6. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

NT$3,532

NT$4,032 total

includes taxes & fees

Oct 21 - Oct 22

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

A multi-story hotel with a central courtyard, parking, and a mountainous backdrop.

A spacious living area with a sofa, chairs, a coffee table, and a TV mounted on the wall.

A bar area with a long counter, multiple stools, and overhead pendant lighting.

7. Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Cassie

NT$4,374

NT$4,985 total

includes taxes & fees

Oct 25 - Oct 26

A modern office space with multiple desks, chairs, and a meeting area.

A reception area with a wooden counter, a large abstract painting above it, and a green carpet. There are shelves with bottled water and snacks on the right.

A hotel with a parking area marked for electric vehicles, a covered walkway, and a clear blue sky.

A hotel room with a large bed, a desk with a phone, a chair, a desk lamp, a painting, and a view of the outdoors.

8. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Herlyn

NT$2,896

NT$3,306 total

includes taxes & fees

Oct 28 - Oct 29

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

A lounge area with a grand piano, blue seating, and a stone wall.

A golf course with a mountain backdrop, surrounded by desert vegetation.

9. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

jennifer

NT$3,770

NT$5,267 total

includes taxes & fees

Oct 20 - Oct 21

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

10. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

Marie

NT$3,315

NT$3,778 total

includes taxes & fees

Oct 26 - Oct 27

A landscaped garden with a fountain, palm trees, and a building with a red roof.

A pool area with a rock formation, palm trees, and lounge chairs.

A tranquil pond with a fountain, surrounded by lush greenery and a large building in the background.

A modern kitchen with a glass dining table, bar stools, and a built-in island with a microwave and oven.

11. Westgate Painted Mountain Golf Resort

17.4 km from Mayo Clinic Scottsdale

Tammie

NT$3,301

NT$3,772 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.

A hotel gym with dumbbells on racks, a bench, and a mirror.

A hotel breakfast area with a self-serve station, seating, and a trash bin.

A swimming pool with lounge chairs and umbrellas, surrounded by a fence and palm trees.

12. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Melanie

NT$3,402

NT$3,877 total

includes taxes & fees

Oct 26 - Oct 27

A hotel room with a bed, desk, chair, television, fireplace, and a dining area.

A hotel room with a bed, a desk with a TV, a sofa, and a coffee table.

A breakfast buffet with various food items and a coffee machine.

A reception area with a counter, two armchairs, and a round table.

13. Sonesta ES Suites Scottsdale Paradise Valley

14 km from Mayo Clinic Scottsdale

Denine

NT$3,856

NT$4,394 total

includes taxes & fees

Oct 25 - Oct 26

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.

A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

14. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Colleen

NT$3,718

NT$4,239 total

includes taxes & fees

Nov 8 - Nov 9

An outdoor patio area with round tables and chairs, a pool in the background, and a covered seating area.

A hotel room with a desk, a bed, a TV, a sofa, a small table, and a view of the outdoors.

A hotel room with a bed, a desk, a chair, a sofa, a small table, and a TV.

A hotel reception area with a large bridge mural, a reception desk, and a snack bar.

15. Staybridge Suites Scottsdale - Talking Stick by IHG

9.7 km from Mayo Clinic Scottsdale

Steve

NT$5,346

NT$6,096 total

includes taxes & fees

Oct 26 - Oct 27

A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.

A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows and a covered patio area.

A Hampton Inn & Suites with a stone facade, a welcoming entrance, and a clear sky at dusk.

An outdoor patio area with stone pillars, fire pit seating, and tables.

16. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Central Scottsdale, 12.3 km from Mayo Clinic Scottsdale

Dana

NT$4,930

NT$5,619 total

includes taxes & fees

Oct 27 - Oct 28

A swimming pool with a water slide, a sun lounger, and a covered seating area.

A reception area with a blue counter, a television screen, and a modern interior design.

A breakfast bar with a variety of baked goods and a sign indicating fresh baked items.

A hotel room with a sofa, a chair, a desk with a television, a lamp, and a framed artwork on the wall.

17. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Ally Marie

NT$5,022

NT$5,724 total

includes taxes & fees

Nov 16 - Nov 17

A spacious lobby with a large seating area, a reception desk, and artwork on the walls.

A buffet counter with various food items, a refrigerator, and a wall-mounted clock.

A spacious lobby with leather armchairs, a patterned rug, and a large metal coffee table.

18. Best Western Plus Scottsdale Thunderbird Suites

Thunderbird Industrial Airpark, 12.1 km from Mayo Clinic Scottsdale

Susan

NT$3,639

NT$4,148 total

includes taxes & fees

Oct 26 - Oct 27

A resort with multiple buildings, a large pool area, and surrounding mountains.

A dining area with a table set for six, overlooking a scenic landscape.

A dining area with a table and chairs, a view of a cityscape, and decorative wall panels.

Three people in a swimming pool with rocks and a red umbrella in the background.

19. ADERO Scottsdale Resort, Autograph Collection

3.6 km from Mayo Clinic Scottsdale

Garrett

NT$6,969

NT$9,252 total

includes taxes & fees

Oct 21 - Oct 22

A building with a symmetrical facade, multiple balconies, and a central entrance.

A conference room with a long table, four chairs, a flat-screen TV mounted on a textured wall, and large windows offering a view of outdoor seating.

A multi-story building with balconies, a central staircase, and outdoor seating with a table and benches.

A multi-story building with a beige facade, large windows, and a central staircase.

20. Hilton Vacation Club Scottsdale Links Resort

11.3 km from Mayo Clinic Scottsdale

Jacob

NT$4,224

NT$5,775 total

includes taxes & fees

Oct 28 - Oct 29

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very good 1,088 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,035 reviews	View
Comfort Suites Scottsdale Talking Stick Entertainment District	9.2 Wonderful 2,056 reviews	View
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale	8.8 Excellent 1,875 reviews	View
Home2 Suites by Hilton Mesa Longbow, AZ	9.6 Exceptional 916 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Sonesta Select Scottsdale at Mayo Clinic Campus

10/10 Excellent

"all good happy place to stay"

Comfort Suites Scottsdale Talking Stick Entertainment District

10/10 Excellent

"Clean room"

Aiden by Best Western Scottsdale North

10/10 Excellent

"We really enjoyed the suite on the lower floor with access to the pool area/patio very comfortable bed, sheets and towels were excellent. I would definitely stay again if we are in the area."

Spark by Hilton Fountain Hills Scottsdale

8/10 Good

"Clean rooms although a slightly weird smell in our room when we arrived. Nothing gross just odd but it went away. Very nice and attentive staff. The continental breakfast could be a little bit nicer, but I definitely think for the size and quality of the hotel, It was expected."

Wekopa Casino Resort

10/10 Excellent

"Beautiful, spacious rooms. Staff was helpful and friendly."

Inn at Eagle Mountain

10/10 Excellent

"A very nice and peaceful place, the surroundings and people were warm and down to earth,I will definitely be coming back."

Holiday Inn & Suites Scottsdale North - Airpark by IHG

10/10 Excellent

"Wonderful personnel, clean environment and easy access to restaurants etc. The only down was the towels were very scratchy. The free Lyft was so convenient and easy to use. I really enjoyed my week."

Sonesta Simply Suites Phoenix Scottsdale

10/10 Excellent

"W"

Tru By Hilton Scottsdale Salt River

10/10 Excellent

"Very clean rooms and the staff very polite and friendly,"

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$3,108

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Be picky

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. Comfort Suites Scottsdale Talking Stick Entertainment District

4. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

5. Home2 Suites by Hilton Mesa Longbow, AZ

6. Fountain Park Hotel, BW Signature Collection

7. Hyatt House North Scottsdale

8. Spark by Hilton Fountain Hills Scottsdale

9. Wekopa Casino Resort

10. Aiden by Best Western Scottsdale North

11. Westgate Painted Mountain Golf Resort

12. Holiday Inn Express Scottsdale North by IHG

13. Sonesta ES Suites Scottsdale Paradise Valley

14. Tru By Hilton Scottsdale Salt River

15. Staybridge Suites Scottsdale - Talking Stick by IHG

16. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

17. Holiday Inn & Suites Scottsdale North - Airpark by IHG

18. Best Western Plus Scottsdale Thunderbird Suites

19. ADERO Scottsdale Resort, Autograph Collection

20. Hilton Vacation Club Scottsdale Links Resort

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Sonesta Select Scottsdale at Mayo Clinic Campus

Comfort Suites Scottsdale Talking Stick Entertainment District

Aiden by Best Western Scottsdale North

Spark by Hilton Fountain Hills Scottsdale

Wekopa Casino Resort

Inn at Eagle Mountain

Holiday Inn & Suites Scottsdale North - Airpark by IHG

Sonesta Simply Suites Phoenix Scottsdale

Tru By Hilton Scottsdale Salt River

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