The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

A breakfast buffet area with various pastries and a sign indicating the price of a cheese danish.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

louis

NT$3,195

NT$3,641 total

includes taxes & fees

Nov 22 - Nov 23

A cluster of modern, multi-story buildings with a river in the foreground.

A dining area with a glass table, wooden chairs, and potted plants.

A golf course with a pond, a clubhouse, and a hilly backdrop.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Stephanie

NT$4,168

NT$4,758 total

includes taxes & fees

Oct 28 - Oct 29

A modern dining area with multiple tables and chairs, a fireplace, and a television mounted on the wall.

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

3. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

LAURA

NT$3,550

NT$4,048 total

includes taxes & fees

Nov 1 - Nov 2

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.

4. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Joseph

NT$2,882

NT$3,285 total

includes taxes & fees

Oct 26 - Oct 27

An outdoor dining table set with chairs, string lights, and a sunset view.

A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.

A multi-story hotel with a prominent entrance, large windows, and a well-lit facade.

A modern lobby with a seating area, a kitchen, and a reception desk.

5. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Claudia

NT$4,545

NT$5,193 total

includes taxes & fees

Nov 22 - Nov 23

A spacious living area with a kitchen, modern furniture, and a fireplace.

A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

6. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

NT$3,492

NT$3,987 total

includes taxes & fees

Oct 26 - Oct 27

A modern hotel with a brick facade, large windows, and a covered entrance area.

An outdoor patio area with round tables and chairs, a fire pit, and a large umbrella.

A modern bar area with a wooden ceiling, bar stools, and a counter with a digital screen.

A hotel room with a desk, two beds, a TV, and a large window.

7. Springhill Suites Phoenix Scottsdale Marriott

18.2 km from Mayo Clinic Scottsdale

Lucinda

NT$3,569

NT$4,068 total

includes taxes & fees

Nov 22 - Nov 23

A hotel room with two beds, a television, a desk with a lamp, and artwork on the wall.

A hotel room with two beds, a desk, a TV, and a balcony with a view.

A modern hotel room with a large window, a desk with a lamp, a chair, and a television.

A hotel reception area with a wooden reception desk, a green carpet, and a yellow kiosk with snacks.

8. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Herbert M Beatty

NT$2,647

NT$3,022 total

includes taxes & fees

Nov 3 - Nov 4

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

A multi-story hotel with a central courtyard, parking, and a mountainous backdrop.

A bar area with a long counter, multiple stools, and overhead pendant lighting.

A reception area with marble reception desks, a wooden ceiling, and a wall-mounted refrigerator.

9. Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Deborah

NT$4,401

NT$5,016 total

includes taxes & fees

Nov 15 - Nov 16

A modern infinity pool with a view of mountains and a sunset.

A modern bar area with a unique ceiling design, a bar counter with multiple screens, and a patterned carpet.

An outdoor seating area with fire pits and lounge chairs, surrounded by trees and a building with illuminated windows in the background.

A poolside lounge with a view of a hotel building, a TV, and a bar area with a bottle of champagne.

10. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Jessica

NT$5,194

NT$6,851 total

includes taxes & fees

Nov 22 - Nov 23

A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.

A restaurant with multiple round tables and bar stools, a self-service beverage dispenser, and a television mounted on the wall.

A hotel room with two beds, a TV, a desk, a chair, and a view of palm trees.

A modern hotel with a covered entrance, multiple floors, and a parking lot.

11. Hyatt Place Phoenix/Mesa

17.8 km from Mayo Clinic Scottsdale

Laura

NT$4,401

NT$5,029 total

includes taxes & fees

Nov 22 - Nov 23

A restaurant setting with round tables, chairs, and empty wine glasses.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A bar area with a bar counter, multiple chairs, and a sofa.

12. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

Marie

NT$3,335

NT$3,801 total

includes taxes & fees

Oct 27 - Oct 28

A landscaped garden with a fountain, palm trees, and a building with a red roof.

A pool area with a rock formation, palm trees, and lounge chairs.

A modern kitchen with a glass dining table, bar stools, and a built-in island with a microwave and oven.

A tranquil pond with a fountain, surrounded by lush greenery and a large building in the background.

13. Westgate Painted Mountain Golf Resort

17.4 km from Mayo Clinic Scottsdale

Curtis

NT$3,270

NT$3,737 total

includes taxes & fees

Nov 1 - Nov 2

A swimming pool with people on inflatable floats, lounge chairs, and umbrellas in the background.

A spacious lobby with a stone wall, a fireplace, and a seating area with a sofa and chairs.

A modern restaurant interior with a central counter displaying food, wooden tables and chairs, and hanging red light fixtures.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

14. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Linda

NT$3,793

NT$5,299 total

includes taxes & fees

Oct 26 - Oct 27

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.

15. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Colleen

NT$3,713

NT$4,234 total

includes taxes & fees

Nov 8 - Nov 9

A hotel with a curved entrance, a flagpole, and palm trees.

A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.

An outdoor patio area with multiple tables and chairs, a barbecue grill, and a view of a building with large windows.

A buffet with various food items in metal containers, including omelets and other dishes.

16. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Linnette

NT$3,195

NT$3,641 total

includes taxes & fees

Nov 23 - Nov 24

A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and a television screen.

A bar area with multiple seating options, a bar counter, and a television screen displaying sports.

A multi-story hotel with a flat roof and balconies, surrounded by well-maintained grass and trees.

A spacious hotel lobby with a reception desk, seating areas, and a view of the dining and kitchen areas.

17. Embassy Suites by Hilton Phoenix Scottsdale

17.8 km from Mayo Clinic Scottsdale

Matthew

NT$4,785

NT$5,411 total

includes taxes & fees

Nov 22 - Nov 23

A hotel dining area with a table and chairs, patterned curtains, and a view through large windows.

A hotel lobby with a bar area, seating, and a reception desk.

A building entrance with a stone facade, large glass doors, and potted plants.

A golf course with sand bunkers, a flagstick, and mountains in the background.

18. Hampton Inn & Suites Scottsdale at Talking Stick

9.1 km from Mayo Clinic Scottsdale

Cynthia

NT$3,852

NT$4,392 total

includes taxes & fees

Nov 22 - Nov 23

A resort with multiple buildings, a large pool area, and surrounding mountains.

A dining area with a table and chairs, a view of a cityscape, and decorative wall panels.

An outdoor wedding reception with round tables set with white chairs, floral centerpieces, and a view of the city in the background.

A dining area with a table set for six, overlooking a scenic landscape.

19. ADERO Scottsdale Resort, Autograph Collection

3.6 km from Mayo Clinic Scottsdale

Garrett

NT$6,814

NT$9,082 total

includes taxes & fees

Oct 31 - Nov 1

A swimming pool with a bridge structure, surrounded by buildings with outdoor seating and a clear sky.

A hotel room with a sofa, a chair, a desk with a television, a lamp, and a framed artwork on the wall.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.

A breakfast bar with a variety of baked goods and a sign indicating fresh baked items.

20. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Ally Marie

NT$4,140

NT$4,719 total

includes taxes & fees

Nov 22 - Nov 23

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very good 1,093 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,036 reviews	View
Comfort Suites Scottsdale Talking Stick Entertainment District	9.2 Wonderful 2,059 reviews	View
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale	8.8 Excellent 1,884 reviews	View
Home2 Suites by Hilton Mesa Longbow, AZ	9.6 Exceptional 921 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

ADERO Scottsdale Resort, Autograph Collection

10/10 Excellent

"Our room was lovely, pools were beautiful with lots of chairs and towels, restaurant was great! We loved the star gazing activity."

Talking Stick Resort

8/10 Good

"The resort was short staffed making getting good service difficult. Luis out at the main pool was amazing and made us feel special. The room was amazing. Was looking forward to sitting out by the fire pits at night but they were never lit and even after asking one night no one showed up to light them. The slot machines very tight seemed like no one was winning on them. Golf course was in great condition but expensive. Resort was very clean with decently priced drinks."

Aiden by Best Western Scottsdale North

10/10 Excellent

"Clean and spacious room"

Staybridge Suites Scottsdale - Talking Stick by IHG

10/10 Excellent

"Very convenient and enjoyable location"

Sonesta Select Scottsdale at Mayo Clinic Campus

10/10 Excellent

"Location is wonderful for appointments I have with Mayo Clinic or hospital"

Inn at Eagle Mountain

8/10 Good

"I think I was able to get one of the last rooms same day....beautiful room, comfortable and spacious, bathroom as well. My view was the parking lot, but next time I will book in advance for hopefully a valley view. Friendly young front desk rep offering wine tasting at that time."

Sonesta Simply Suites Phoenix Scottsdale

10/10 Excellent

"Great price! It was actually a suitet with a kitchenette although I didn't use it. I would definitely stay there again if I was in the area!"

Spark by Hilton Fountain Hills Scottsdale

8/10 Good

"Excellent value for a traveler."

Home2 Suites by Hilton Scottsdale Salt River

10/10 Excellent

"Everything was perfect. Coffee ready in lobby at 4am every morning!"

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$3,022

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. Comfort Suites Scottsdale Talking Stick Entertainment District

4. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

5. Home2 Suites by Hilton Mesa Longbow, AZ

6. Fountain Park Hotel, BW Signature Collection

7. Springhill Suites Phoenix Scottsdale Marriott

8. Spark by Hilton Fountain Hills Scottsdale

9. Hyatt House North Scottsdale

10. Talking Stick Resort

11. Hyatt Place Phoenix/Mesa

12. Aiden by Best Western Scottsdale North

13. Westgate Painted Mountain Golf Resort

14. Wekopa Casino Resort

15. Tru By Hilton Scottsdale Salt River

16. Holiday Inn Express Scottsdale North by IHG

17. Embassy Suites by Hilton Phoenix Scottsdale

18. Hampton Inn & Suites Scottsdale at Talking Stick

19. ADERO Scottsdale Resort, Autograph Collection

20. Holiday Inn & Suites Scottsdale North - Airpark by IHG

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

ADERO Scottsdale Resort, Autograph Collection

Talking Stick Resort

Aiden by Best Western Scottsdale North

Staybridge Suites Scottsdale - Talking Stick by IHG

Sonesta Select Scottsdale at Mayo Clinic Campus

Inn at Eagle Mountain

Sonesta Simply Suites Phoenix Scottsdale

Spark by Hilton Fountain Hills Scottsdale

Home2 Suites by Hilton Scottsdale Salt River

Frequently asked questions

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