The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

A breakfast buffet area with various pastries and a sign indicating the price of a cheese danish.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

Michael

NT$2,593

NT$2,956 total

includes taxes & fees

Oct 1 - Oct 2

A cluster of modern, multi-story buildings with a river in the foreground.

A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

A golf course with a pond, a clubhouse, and a hilly backdrop.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Andrei

NT$3,579

NT$4,086 total

includes taxes & fees

Sep 30 - Oct 1

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Cathleen

NT$2,618

NT$2,984 total

includes taxes & fees

Sep 30 - Oct 1

A hotel room with two beds, a TV, a desk, and a window with a view.

A modern office space with multiple desks, chairs, and a meeting area.

A hotel room with two beds, a desk, a TV, and a balcony with a view.

A pool area with a clear blue pool, lounge chairs, and a multi-story building with balconies.

4. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Peyton

NT$2,448

NT$2,795 total

includes taxes & fees

Oct 5 - Oct 6

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

5. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

William

NT$3,112

NT$3,548 total

includes taxes & fees

Sep 30 - Oct 1

A spacious living area with a kitchen, modern furniture, and a fireplace.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.

6. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

NT$2,985

NT$3,408 total

includes taxes & fees

Sep 30 - Oct 1

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

A lounge area with a grand piano, blue seating, and a stone wall.

A dining area with a large table set for six, surrounded by chairs, with a view of cacti and a stone wall outside.

7. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Darrick

NT$3,491

NT$5,852 total

includes taxes & fees

Sep 30 - Oct 1

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A bar area with a bar counter, multiple chairs, and a sofa.

A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.

8. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

cody

NT$2,734

NT$3,116 total

includes taxes & fees

Sep 30 - Oct 1

A modern infinity pool with a view of mountains and a sunset.

A modern bar area with a unique ceiling design, a bar counter with multiple screens, and a patterned carpet.

An outdoor seating area with fire pits and lounge chairs, surrounded by trees and a building with illuminated windows in the background.

A poolside lounge with a view of a hotel building, a TV, and a bar area with a bottle of champagne.

9. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Meghan Rebbecca

NT$6,744

NT$8,595 total

includes taxes & fees

Oct 1 - Oct 2

An outdoor dining table set with chairs, string lights, and a sunset view.

A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.

A modern living room with a sectional sofa, orange ottomans, a dining area, and a kitchen with a stone accent wall.

A multi-story hotel with a prominent entrance, large windows, and a well-lit facade.

10. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Damon

NT$5,030

NT$5,748 total

includes taxes & fees

Oct 1 - Oct 2

A resort with multiple buildings, a large pool area, and surrounding mountains.

Three people in a swimming pool with rocks and a red umbrella in the background.

A dining area with a table and chairs, a view of a cityscape, and decorative wall panels.

An outdoor wedding reception with round tables set with white chairs, floral centerpieces, and a view of the city in the background.

11. ADERO Scottsdale Resort, Autograph Collection

3.6 km from Mayo Clinic Scottsdale

Karen

NT$7,367

NT$9,680 total

includes taxes & fees

Oct 2 - Oct 3

A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.

A hotel breakfast area with a self-serve station, seating, and a trash bin.

A swimming pool with lounge chairs and umbrellas, surrounded by a fence and palm trees.

A hotel gym with dumbbells on racks, a bench, and a mirror.

12. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Melanie

NT$2,794

NT$3,185 total

includes taxes & fees

Oct 25 - Oct 26

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.

13. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Colleen

NT$3,880

NT$4,424 total

includes taxes & fees

Oct 25 - Oct 26

A hotel dining area with a table and chairs, patterned curtains, and a view through large windows.

A building entrance with a stone facade, large glass doors, and potted plants.

A hotel lobby with a bar area, seating, and a reception desk.

A hotel room with a large window, a desk, a bed, a TV, and a chair.

14. Hampton Inn & Suites Scottsdale at Talking Stick

9.1 km from Mayo Clinic Scottsdale

Mark

NT$3,880

NT$4,424 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor patio area with round tables and chairs, a pool in the background, and a covered seating area.

A hotel reception area with a large bridge mural, a reception desk, and a snack bar.

A hotel room with a bed, a desk, a chair, a sofa, a small table, and a TV.

A multi-story hotel with illuminated signage reading "Talking Stick" and "Resort".

15. Staybridge Suites Scottsdale - Talking Stick by IHG

9.7 km from Mayo Clinic Scottsdale

Gentry

NT$4,958

NT$5,653 total

includes taxes & fees

Oct 1 - Oct 2

A hotel room with a bed, desk, chair, television, fireplace, and a dining area.

An outdoor patio with a grill, table, and chairs.

A hotel room with a bed, a desk with a TV, a sofa, and a coffee table.

A breakfast buffet with various food items and a coffee machine.

16. Sonesta ES Suites Scottsdale Paradise Valley

14 km from Mayo Clinic Scottsdale

Michael

NT$3,811

NT$4,343 total

includes taxes & fees

Oct 15 - Oct 16

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

A multi-story hotel with a central courtyard, parking, and a mountainous backdrop.

A spacious living area with a sofa, chairs, a coffee table, and a TV mounted on the wall.

A bar area with a long counter, multiple stools, and overhead pendant lighting.

17. Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Slyqavious

NT$4,287

NT$4,886 total

includes taxes & fees

Oct 21 - Oct 22

A circular fire feature with a stone border, surrounded by a landscaped garden with cacti and shrubs, under a sunset sky.

A modern bar area with seating, a digital menu display, and a beverage refrigerator.

A Courtyard by Marriott hotel with a modern design, featuring a covered entrance and stone pillars.

A modern lobby with a central water feature, seating area, and a stone pillar.

18. Courtyard Scottsdale Salt River

12.2 km from Mayo Clinic Scottsdale

Karl

NT$4,640

NT$5,288 total

includes taxes & fees

Oct 11 - Oct 12

A breakfast bar with a variety of baked goods and a sign indicating fresh baked items.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.

A hotel room with a flat-screen TV, a fireplace, a sofa, a coffee table, and a large window with a view.

A hotel room with a sofa, a chair, a desk with a television, a lamp, and a framed artwork on the wall.

19. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Ally Marie

NT$4,414

NT$5,031 total

includes taxes & fees

Oct 25 - Oct 26

A hotel pool area with sun loungers, a children's play area, and a building with a sign.

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

An outdoor patio area with round tables and white wicker chairs, red umbrellas, and potted plants.

A modern kitchen with a central island, bar stools, and a sign that reads "inspired table".

20. Home2 Suites by Hilton Scottsdale Salt River

9.6 km from Mayo Clinic Scottsdale

Kate

NT$4,406

NT$5,024 total

includes taxes & fees

Oct 25 - Oct 26

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very good 1,102 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,017 reviews	View
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale	8.8 Excellent 1,862 reviews	View
Spark by Hilton Fountain Hills Scottsdale	8.8 Excellent 318 reviews	View
Comfort Suites Scottsdale Talking Stick Entertainment District	9.2 Wonderful 2,033 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Aiden by Best Western Scottsdale North

8/10 Good

"Hot tub was not working, 11 dollars for typical breakfast that is usually free."

Fountain Park Hotel, BW Signature Collection

10/10 Excellent

"We will return to this hotel."

Inn at Eagle Mountain

10/10 Excellent

"Beautiful and quiet location. Nice place to stay and relax. Room is clean and well maintained. Highly recommend."

Wekopa Casino Resort

10/10 Excellent

"Rooms clean, breakfast super. Playing golf they will run ya right to the front door of clubhouse! Outstanding stay!"

Spark by Hilton Fountain Hills Scottsdale

8/10 Good

"Highly recommended for the price you pay"

Hampton Inn & Suites Scottsdale at Talking Stick

10/10 Excellent

"It’s what I usually expect for a Hampton Inn. Clean, cheap, easy quiet. No surprises. The free waffles closed the deal."

Sonesta Simply Suites Phoenix Scottsdale

10/10 Excellent

"The microwave didn't have a rotating plate. There was a coffee pot but no coffee. Only one cup for two people. One bowl, no plates. Therefore, kitchen amenities were incomplete."

Great Wolf Lodge Arizona

10/10 Excellent

"O"

Staybridge Suites Scottsdale - Talking Stick by IHG

10/10 Excellent

"The breakfast was fantastic!!"

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 21 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 21 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,795

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

4. Spark by Hilton Fountain Hills Scottsdale

5. Comfort Suites Scottsdale Talking Stick Entertainment District

6. Fountain Park Hotel, BW Signature Collection

7. Wekopa Casino Resort

8. Aiden by Best Western Scottsdale North

9. Talking Stick Resort

10. Home2 Suites by Hilton Mesa Longbow, AZ

11. ADERO Scottsdale Resort, Autograph Collection

12. Holiday Inn Express Scottsdale North by IHG

13. Tru By Hilton Scottsdale Salt River

14. Hampton Inn & Suites Scottsdale at Talking Stick

15. Staybridge Suites Scottsdale - Talking Stick by IHG

16. Sonesta ES Suites Scottsdale Paradise Valley

17. Hyatt House North Scottsdale

18. Courtyard Scottsdale Salt River

19. Holiday Inn & Suites Scottsdale North - Airpark by IHG

20. Home2 Suites by Hilton Scottsdale Salt River

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Aiden by Best Western Scottsdale North

Fountain Park Hotel, BW Signature Collection

Inn at Eagle Mountain

Wekopa Casino Resort

Spark by Hilton Fountain Hills Scottsdale

Hampton Inn & Suites Scottsdale at Talking Stick

Sonesta Simply Suites Phoenix Scottsdale

Great Wolf Lodge Arizona

Staybridge Suites Scottsdale - Talking Stick by IHG

Frequently asked questions

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