The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

A breakfast buffet area with various pastries and a sign indicating the price of a cheese danish.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

Teri

NT$2,118

NT$2,414 total

includes taxes & fees

Sep 4 - Sep 5

A cluster of modern, multi-story buildings with a river in the foreground.

A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

A golf course with a pond, a clubhouse, and a hilly backdrop.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Lucia

NT$2,796

NT$3,192 total

includes taxes & fees

Aug 31 - Sep 1

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

A multi-story hotel with a parking lot and a road leading to a roundabout.

A bar area with a long counter, multiple bar stools, and overhead lighting.

A hotel room with two beds, a desk, a sofa, and a TV.

3. Hyatt Place North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Derrick

NT$2,150

NT$2,450 total

includes taxes & fees

Sep 6 - Sep 7

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

4. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

cody

NT$2,485

NT$2,832 total

includes taxes & fees

Aug 31 - Sep 1

A circular fire feature with a stone border, surrounded by a landscaped garden with cacti and shrubs, under a sunset sky.

A modern bar area with seating, a digital menu display, and a beverage refrigerator.

A pool area with lounge chairs and umbrellas, surrounded by buildings with balconies and outdoor seating.

A Courtyard by Marriott hotel with a modern design, featuring a covered entrance and stone pillars.

5. Courtyard Scottsdale Salt River

12.2 km from Mayo Clinic Scottsdale

Karl

NT$2,561

NT$2,919 total

includes taxes & fees

Sep 6 - Sep 7

A hotel room with two beds, a TV, a desk, and a window with a view.

A modern hotel room with a large window, a desk with a lamp, a microwave, and a chair.

A pool area with a clear blue pool, lounge chairs, and a multi-story building with balconies.

A hotel room with two beds, a desk, a TV, and a balcony with a view.

6. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Jim

NT$2,178

NT$2,487 total

includes taxes & fees

Sep 4 - Sep 5

An outdoor dining table set with chairs, string lights, and a sunset view.

A modern lobby with a seating area, a kitchen, and a reception desk.

A modern living room with a sectional sofa, orange ottomans, a dining area, and a kitchen with a stone accent wall.

A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.

7. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Marie

NT$3,275

NT$3,742 total

includes taxes & fees

Sep 3 - Sep 4

A hotel room with a sofa, a chair, a desk with a television, a lamp, and a framed artwork on the wall.

A breakfast bar with a variety of baked goods and a sign indicating fresh baked items.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a landscaped entrance area with palm trees and shrubs.

A swimming pool with a bridge structure, surrounded by buildings with outdoor seating and a clear sky.

8. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Christiaan Leonard

NT$2,782

NT$3,171 total

includes taxes & fees

Sep 6 - Sep 7

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A golf course with a mountain backdrop, surrounded by desert vegetation.

A lounge area with a grand piano, blue seating, and a stone wall.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

9. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

NT$4,018

NT$6,447 total

includes taxes & fees

Aug 30 - Aug 31

A modern infinity pool with a view of mountains and a sunset.

An outdoor seating area with fire pits and lounge chairs, surrounded by trees and a building with illuminated windows in the background.

A restaurant with high tables and booths, floral wall decorations, and a view of the mountains.

A poolside lounge with a view of a hotel building, a TV, and a bar area with a bottle of champagne.

10. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Daryl

NT$4,203

NT$5,697 total

includes taxes & fees

Sep 7 - Sep 8

A spacious living area with a kitchen, modern furniture, and a fireplace.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

A spacious lobby with a high ceiling, modern chandeliers, a fire feature, and a large TV screen.

11. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Emily

NT$2,656

NT$3,032 total

includes taxes & fees

Sep 1 - Sep 2

A resort with multiple buildings, a large pool area, and surrounding mountains.

Three people in a swimming pool with rocks and a red umbrella in the background.

A dining area with a table set for six, overlooking a scenic landscape.

A dining area with a table and chairs, a view of a cityscape, and decorative wall panels.

12. ADERO Scottsdale Resort, Autograph Collection

3.6 km from Mayo Clinic Scottsdale

Bassim

NT$4,184

NT$6,044 total

includes taxes & fees

Aug 30 - Aug 31

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

A spacious living area with a sofa, chairs, a coffee table, and a TV mounted on the wall.

A multi-story hotel with a central courtyard, parking, and a mountainous backdrop.

A reception area with marble reception desks, a wooden ceiling, and a wall-mounted refrigerator.

13. Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Christopher

NT$2,909

NT$3,315 total

includes taxes & fees

Aug 31 - Sep 1

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

14. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Andrea

NT$2,443

NT$2,786 total

includes taxes & fees

Sep 13 - Sep 14

A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.

A Hampton Inn & Suites with a stone facade, a welcoming entrance, and a clear sky at dusk.

A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows and a covered patio area.

A modern kitchen with dark wooden cabinets, a white countertop, and a black refrigerator.

15. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Central Scottsdale, 12.3 km from Mayo Clinic Scottsdale

Dana

NT$3,301

NT$3,762 total

includes taxes & fees

Sep 7 - Sep 8

An outdoor patio area with a central fire feature, seating arrangements, and a covered walkway.

A modern lounge area with a large flat-screen TV, comfortable seating, and a large window offering a view of the outdoors.

A multi-story residential building with balconies, a landscaped courtyard with seating, and a fire pit.

A modern lounge area with dark blue upholstered chairs, round tables, and a leather sofa.

16. Residence Inn Scottsdale Salt River

12 km from Mayo Clinic Scottsdale

Michael

NT$3,510

NT$4,002 total

includes taxes & fees

Sep 4 - Sep 5

An outdoor seating area with fire pit, red Adirondack chairs, and a covered patio with string lights.

A multi-story hotel with a modern design, featuring a prominent 'Home Suites by Hilton' sign.

A modern hotel lobby with a variety of seating options, including tables and chairs, a sofa area, and a reception desk.

A modern hotel room with a dining area, a bed, a desk, and a view of the city.

17. Home2 Suites by Hilton Scottsdale North

15 km from Mayo Clinic Scottsdale

Eloiza

NT$2,567

NT$2,925 total

includes taxes & fees

Sep 6 - Sep 7

A hotel with a modern design, featuring a curved roof, large windows, and a landscaped entrance area with palm trees and shrubs.

A swimming pool with lounge chairs and umbrellas, surrounded by a fence and palm trees.

A hotel with a curved entrance, a flagpole, and palm trees.

A hotel dining area with multiple tables and chairs, framed artwork on the walls, and potted plants.

18. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Valeria

NT$2,498

NT$2,847 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with a bed, desk, television, fireplace, and seating area.

A hotel room with a bed, a desk, a TV, a sofa, and a chair.

A breakfast buffet with various food items and a coffee machine.

A reception area with a counter, two armchairs, and a round table.

19. Sonesta ES Suites Scottsdale Paradise Valley

14 km from Mayo Clinic Scottsdale

Jonathan

NT$2,251

NT$2,565 total

includes taxes & fees

Sep 6 - Sep 7

A spacious lobby with stone walls, comfortable seating, and a large window offering a mountain view.

A spacious outdoor lounge area with a fire feature, comfortable seating, a bar with a view, and a stone wall.

A spacious lobby with a central table set for a small gathering, flanked by seating and a modern ceiling design.

A spacious restaurant with wooden flooring, high tables, and chairs, featuring a bar area and large windows overlooking a scenic view.

20. Hilton North Scottsdale At Cavasson

13.4 km from Mayo Clinic Scottsdale

Contantine

NT$4,382

NT$4,994 total

includes taxes & fees

Sep 4 - Sep 5

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very Good 1,097 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,009 reviews	View
Hyatt Place North Scottsdale	9.4 Exceptional 1,228 reviews	View
Aiden by Best Western Scottsdale North	9.0 Wonderful 1,148 reviews	View
Courtyard Scottsdale Salt River	9.4 Exceptional 996 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Aiden by Best Western Scottsdale North

10/10 Excellent

"The room was beautiful and super clean. Great location for a hotel. Private enough"

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

10/10 Excellent

"It's convenient to shopping, eating, movie theater,golfing and gambling. There breakfast is ok. They could add a few more options but looking at their space where they set up would not allow it. Rooms clean and the beds are super comfy."

Sonesta Select Scottsdale at Mayo Clinic Campus

10/10 Excellent

"Very convenient to Mayo (basically in the same parking lot). Clean, reasonable, good bed and AC (it was 107). AC was a little noisy and the Starbucks at front was only breakfast, but all good. Staff were great. I’ll stay again."

Hampton Inn & Suites Scottsdale at Talking Stick

10/10 Excellent

"It’s a cool place to sleep at. It felt safe and pretty clean. Eric at the front desk was awesome!"

Tru By Hilton Scottsdale Salt River

8/10 Good

"Smaller than I expected. Rooms are smaller in square footage and not much of a great view if facing north. Breakfast was plain. Clean room. Nice staff. Pool table was neat. Quiet. Overall decent."

Fountain Park Hotel, BW Signature Collection

10/10 Excellent

"Clean comfortable rooms, plenty of place s and things to do in walking distance, right across from fountain park"

ADERO Scottsdale Resort, Autograph Collection

10/10 Excellent

"Great place to get away"

Home2 Suites by Hilton Scottsdale Salt River

8/10 Good

"Breakfast wasn't best. Eggs & sausage cold."

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 24 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 24 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, McDowell Mountain Golf Club, or Golf Club at Eagle Mountain are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,414

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. Hyatt Place North Scottsdale

4. Aiden by Best Western Scottsdale North

5. Courtyard Scottsdale Salt River

6. Spark by Hilton Fountain Hills Scottsdale

7. Home2 Suites by Hilton Mesa Longbow, AZ

8. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9. Wekopa Casino Resort

10. Talking Stick Resort

11. Fountain Park Hotel, BW Signature Collection

12. ADERO Scottsdale Resort, Autograph Collection

13. Hyatt House North Scottsdale

14. Tru By Hilton Scottsdale Salt River

15. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

16. Residence Inn Scottsdale Salt River

17. Home2 Suites by Hilton Scottsdale North

18. Holiday Inn Express Scottsdale North by IHG

19. Sonesta ES Suites Scottsdale Paradise Valley

20. Hilton North Scottsdale At Cavasson

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Aiden by Best Western Scottsdale North

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Sonesta Select Scottsdale at Mayo Clinic Campus

Hampton Inn & Suites Scottsdale at Talking Stick

Tru By Hilton Scottsdale Salt River

Fountain Park Hotel, BW Signature Collection

ADERO Scottsdale Resort, Autograph Collection

Home2 Suites by Hilton Scottsdale Salt River

Frequently asked questions

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