The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

A breakfast buffet area with various pastries and a sign indicating the price of a cheese danish.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

Michael

NT$3,409

NT$3,885 total

includes taxes & fees

Oct 4 - Oct 5

A cluster of modern, multi-story buildings with a river in the foreground.

A golf course with a pond, a clubhouse, and a hilly backdrop.

A dining area with a glass table, wooden chairs, and potted plants.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Andrei

NT$4,258

NT$4,861 total

includes taxes & fees

Oct 28 - Oct 29

An outdoor dining table set with chairs, string lights, and a sunset view.

A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.

A multi-story hotel with a prominent entrance, large windows, and a well-lit facade.

A modern lobby with a seating area, a kitchen, and a reception desk.

3. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Damon

NT$4,856

NT$5,549 total

includes taxes & fees

Nov 1 - Nov 2

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

4. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Cathleen

NT$2,681

NT$3,055 total

includes taxes & fees

Oct 25 - Oct 26

A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.

A hotel room with two beds, a TV, a desk, a chair, and a view of palm trees.

A modern hotel with a covered entrance, multiple floors, and a parking lot.

A modern lobby with a brick wall, seating area, and a flat-screen TV.

5. Hyatt Place Phoenix/Mesa

17.8 km from Mayo Clinic Scottsdale

greg

NT$3,985

NT$4,554 total

includes taxes & fees

Oct 5 - Oct 6

A wooden door with a glass panel, a doormat, and a small window above it.

A modern kitchen with white cabinets, a built-in oven, and a large window.

A bedroom with a desk, a bed, a ceiling fan, and a window with blinds.

6. Close to Hiking! Family-friendly Mesa Retreat

13.6 km from Mayo Clinic Scottsdale

NT$5,734

NT$24,943 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with two beds, a TV, a desk, and a window with a view.

A modern office space with multiple desks, chairs, and a meeting area.

A hotel room with two beds, a desk, a TV, and a balcony with a view.

A pool area with a clear blue pool, lounge chairs, and a multi-story building with balconies.

7. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Patricia

NT$2,464

NT$2,813 total

includes taxes & fees

Oct 15 - Oct 16

A spacious living area with a kitchen, modern furniture, and a fireplace.

A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

A spacious lobby with a high ceiling, modern chandeliers, a fire feature, and a large TV screen.

8. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

NT$3,472

NT$3,964 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

A golf course with a mountain backdrop, surrounded by desert vegetation.

A lounge area with a grand piano, blue seating, and a stone wall.

9. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Darrick

NT$3,517

NT$5,895 total

includes taxes & fees

Oct 4 - Oct 5

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A bar area with a bar counter, multiple chairs, and a sofa.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

10. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

cody

NT$2,719

NT$3,098 total

includes taxes & fees

Oct 4 - Oct 5

A modern infinity pool with a view of mountains and a sunset.

An outdoor seating area with fire pits and lounge chairs, surrounded by trees and a building with illuminated windows in the background.

A poolside lounge with a view of a hotel building, a TV, and a bar area with a bottle of champagne.

A restaurant with high tables and booths, floral wall decorations, and a view of the mountains.

11. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Meghan Rebbecca

NT$6,243

NT$8,027 total

includes taxes & fees

Oct 5 - Oct 6

A modern hotel with a brick facade, large windows, and a covered entrance area.

A hotel room with a desk, two beds, a TV, and a large window.

An outdoor patio area with round tables and chairs, a fire pit, and a large umbrella.

A modern lobby with a sectional sofa, a round coffee table, and a mural on the wall.

12. Springhill Suites Phoenix Scottsdale Marriott

18.2 km from Mayo Clinic Scottsdale

Marie

NT$4,094

NT$4,666 total

includes taxes & fees

Oct 11 - Oct 12

A hotel pool area with sun loungers, a children's play area, and a building with a sign.

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

An outdoor patio area with round tables and white wicker chairs, red umbrellas, and potted plants.

A hotel room with a bed, a green sofa, a TV, a desk, and a green carpet.

13. Home2 Suites by Hilton Scottsdale Salt River

9.6 km from Mayo Clinic Scottsdale

Kate

NT$4,174

NT$4,759 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and a television screen.

An outdoor seating area with a fire feature, surrounded by a fence and palm trees, under a sunset sky.

A bar area with multiple seating options, a bar counter, and a television screen displaying sports.

A multi-story hotel with a flat roof and balconies, surrounded by well-maintained grass and trees.

14. Embassy Suites by Hilton Phoenix Scottsdale

17.8 km from Mayo Clinic Scottsdale

Maria Antoinette

NT$4,945

NT$5,591 total

includes taxes & fees

Oct 8 - Oct 9

A breakfast bar with a variety of baked goods and a sign indicating fresh baked items.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.

A hotel room with a sofa, a chair, a desk with a television, a lamp, and a framed artwork on the wall.

A hotel room with a flat-screen TV, a fireplace, a sofa, a coffee table, and a large window with a view.

15. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Ally Marie

NT$4,428

NT$5,047 total

includes taxes & fees

Oct 25 - Oct 26

A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.

A modern kitchen with dark wooden cabinets, a white countertop, and a black refrigerator.

A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows and a covered patio area.

An outdoor patio area with stone pillars, fire pit seating, and tables.

16. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Central Scottsdale, 12.3 km from Mayo Clinic Scottsdale

Dana

NT$5,068

NT$5,776 total

includes taxes & fees

Oct 25 - Oct 26

A spacious lobby with stone walls, comfortable seating, and a large window offering a mountain view.

A spacious lobby with a central table set for a small gathering, flanked by seating and a modern ceiling design.

A spacious outdoor lounge area with a fire feature, comfortable seating, a bar with a view, and a stone wall.

A spacious restaurant with wooden flooring, high tables, and chairs, featuring a bar area and large windows overlooking a scenic view.

17. Hilton North Scottsdale At Cavasson

13.4 km from Mayo Clinic Scottsdale

Marcos

NT$8,806

NT$10,036 total

includes taxes & fees

Oct 9 - Oct 10

A circular fire feature with a stone border, surrounded by a landscaped garden with cacti and shrubs, under a sunset sky.

A Courtyard by Marriott hotel with a modern design, featuring a covered entrance and stone pillars.

A modern lobby with a central water feature, seating area, and a stone pillar.

A modern bar area with seating, a digital menu display, and a beverage refrigerator.

18. Courtyard Scottsdale Salt River

12.2 km from Mayo Clinic Scottsdale

Karl

NT$4,674

NT$5,327 total

includes taxes & fees

Oct 11 - Oct 12

A resort with multiple buildings, a large pool area, and surrounding mountains.

Three people in a swimming pool with rocks and a red umbrella in the background.

A dining area with a table and chairs, a view of a cityscape, and decorative wall panels.

A dining area with a table set for six, overlooking a scenic landscape.

19. ADERO Scottsdale Resort, Autograph Collection

3.6 km from Mayo Clinic Scottsdale

Truzanne

NT$7,907

NT$10,307 total

includes taxes & fees

Oct 11 - Oct 12

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.

An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

20. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Colleen

NT$3,835

NT$4,373 total

includes taxes & fees

Nov 1 - Nov 2

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very good 1,103 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,022 reviews	View
Home2 Suites by Hilton Mesa Longbow, AZ	9.6 Exceptional 906 reviews	View
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale	8.8 Excellent 1,852 reviews	View
Hyatt Place Phoenix/Mesa	9.2 Wonderful 1,998 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Talking Stick Resort

10/10 Excellent

"The room was neat and tidy. The view is beautiful. It was my first time flying to Phoenix. The casino had many slots to choose from. Will be visiting again."

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

10/10 Excellent

"Employees were great! Also excellent location"

Comfort Suites Scottsdale Talking Stick Entertainment District

10/10 Excellent

"Clean large rooms. Great staff. Friendly. Breakfast definitely a great value. Location was great."

ADERO Scottsdale Resort, Autograph Collection

10/10 Excellent

"Great rooms and hotel, staff very helpful at all times and the relaxation was perfect."

Home2 Suites by Hilton Scottsdale Salt River

8/10 Good

"Quiet location and great staff."

Great Wolf Lodge Arizona

10/10 Excellent

"Facilities are amazing for families with kids. Please note there’s no in-room safe for your money,passports belonging."

Fountain Park Hotel, BW Signature Collection

10/10 Excellent

"We will return to this hotel."

Sonesta Simply Suites Phoenix Scottsdale

10/10 Excellent

"The microwave didn't have a rotating plate. There was a coffee pot but no coffee. Only one cup for two people. One bowl, no plates. Therefore, kitchen amenities were incomplete."

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,813

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. Home2 Suites by Hilton Mesa Longbow, AZ

4. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

5. Hyatt Place Phoenix/Mesa

6. Close to Hiking! Family-friendly Mesa Retreat

7. Spark by Hilton Fountain Hills Scottsdale

8. Fountain Park Hotel, BW Signature Collection

9. Wekopa Casino Resort

10. Aiden by Best Western Scottsdale North

11. Talking Stick Resort

12. Springhill Suites Phoenix Scottsdale Marriott

13. Home2 Suites by Hilton Scottsdale Salt River

14. Embassy Suites by Hilton Phoenix Scottsdale

15. Holiday Inn & Suites Scottsdale North - Airpark by IHG

16. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

17. Hilton North Scottsdale At Cavasson

18. Courtyard Scottsdale Salt River

19. ADERO Scottsdale Resort, Autograph Collection

20. Tru By Hilton Scottsdale Salt River

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Talking Stick Resort

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Comfort Suites Scottsdale Talking Stick Entertainment District

ADERO Scottsdale Resort, Autograph Collection

Home2 Suites by Hilton Scottsdale Salt River

Great Wolf Lodge Arizona

Fountain Park Hotel, BW Signature Collection

Sonesta Simply Suites Phoenix Scottsdale

Frequently asked questions

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