The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

A breakfast buffet area with various pastries and a sign indicating the price of a cheese danish.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

Michael

NT$3,063

NT$3,491 total

includes taxes & fees

Oct 1 - Oct 2

A cluster of modern, multi-story buildings with a river in the foreground.

A dining area with a glass table, wooden chairs, and potted plants.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Andrei

NT$5,054

NT$5,770 total

includes taxes & fees

Oct 5 - Oct 6

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Cathleen

NT$2,685

NT$3,060 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor dining table set with chairs, string lights, and a sunset view.

A modern living room with a sectional sofa, orange ottomans, a dining area, and a kitchen with a stone accent wall.

A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.

A modern lobby with a seating area, a kitchen, and a reception desk.

4. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Damon

NT$5,285

NT$6,039 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

A modern hotel lobby with a central bar area, seating arrangements, and a clean, contemporary design.

5. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

William

NT$3,302

NT$3,765 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with two beds, a TV, a desk, and a window with a view.

A pool area with a clear blue pool, lounge chairs, and a multi-story building with balconies.

A modern hotel room with a large window, a desk with a lamp, a microwave, and a chair.

A modern office space with multiple desks, chairs, and a meeting area.

6. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Peyton

NT$2,459

NT$2,808 total

includes taxes & fees

Oct 7 - Oct 8

A spacious living area with a kitchen, modern furniture, and a fireplace.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

A spacious lobby with a high ceiling, modern chandeliers, a fire feature, and a large TV screen.

7. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

NT$2,999

NT$3,424 total

includes taxes & fees

Oct 1 - Oct 2

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A lounge area with a grand piano, blue seating, and a stone wall.

A golf course with a mountain backdrop, surrounded by desert vegetation.

A dining area with a large table set for six, surrounded by chairs, with a view of cacti and a stone wall outside.

8. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Darrick

NT$3,505

NT$5,875 total

includes taxes & fees

Oct 4 - Oct 5

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

A bar area with a bar counter, multiple chairs, and a sofa.

9. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

cody

NT$2,999

NT$3,418 total

includes taxes & fees

Oct 1 - Oct 2

A modern infinity pool with a view of mountains and a sunset.

A poolside lounge with a view of a hotel building, a TV, and a bar area with a bottle of champagne.

An outdoor seating area with fire pits and lounge chairs, surrounded by trees and a building with illuminated windows in the background.

A modern bar area with a unique ceiling design, a bar counter with multiple screens, and a patterned carpet.

10. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Meghan Rebbecca

NT$6,558

NT$8,387 total

includes taxes & fees

Oct 5 - Oct 6

A hotel room with a bed, desk, chair, television, fireplace, and a dining area.

A reception area with a counter, two armchairs, and a round table.

A breakfast buffet with various food items and a coffee machine.

An outdoor patio with a grill, table, and chairs.

11. Sonesta ES Suites Scottsdale Paradise Valley

14 km from Mayo Clinic Scottsdale

Michael

NT$3,861

NT$4,400 total

includes taxes & fees

Oct 14 - Oct 15

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

A multi-story hotel with a central courtyard, parking, and a mountainous backdrop.

A bar area with a long counter, multiple stools, and overhead pendant lighting.

A spacious living area with a sofa, chairs, a coffee table, and a TV mounted on the wall.

12. Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Slyqavious

NT$4,307

NT$4,909 total

includes taxes & fees

Oct 21 - Oct 22

An outdoor patio area with round tables and chairs, a pool in the background, and a covered seating area.

A hotel room with a desk, a bed, a TV, a sofa, a small table, and a view of the outdoors.

A multi-story hotel with illuminated signage reading "Talking Stick" and "Resort".

A hotel reception area with a large bridge mural, a reception desk, and a snack bar.

13. Staybridge Suites Scottsdale - Talking Stick by IHG

9.7 km from Mayo Clinic Scottsdale

Gentry

NT$5,232

NT$5,966 total

includes taxes & fees

Oct 1 - Oct 2

A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.

A hotel breakfast area with a self-serve station, seating, and a trash bin.

A hotel gym with dumbbells on racks, a bench, and a mirror.

A swimming pool with lounge chairs and umbrellas, surrounded by a fence and palm trees.

14. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Melanie

NT$2,935

NT$3,345 total

includes taxes & fees

Oct 4 - Oct 5

A hotel dining area with a table and chairs, patterned curtains, and a view through large windows.

A golf course with sand bunkers, a flagstick, and mountains in the background.

A hotel room with a large window, a desk, a bed, a TV, and a chair.

A hotel lobby with a bar area, seating, and a reception desk.

15. Hampton Inn & Suites Scottsdale at Talking Stick

9.1 km from Mayo Clinic Scottsdale

Mark

NT$3,898

NT$4,445 total

includes taxes & fees

Oct 11 - Oct 12

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

16. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Colleen

NT$3,898

NT$4,445 total

includes taxes & fees

Oct 25 - Oct 26

A resort with multiple buildings, a large pool area, and surrounding mountains.

Three people in a swimming pool with rocks and a red umbrella in the background.

A dining area with a table set for six, overlooking a scenic landscape.

A dining area with a table and chairs, a view of a cityscape, and decorative wall panels.

17. ADERO Scottsdale Resort, Autograph Collection

3.6 km from Mayo Clinic Scottsdale

Karen

NT$7,591

NT$9,942 total

includes taxes & fees

Oct 1 - Oct 2

A breakfast bar with a variety of baked goods and a sign indicating fresh baked items.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.

A hotel room with a flat-screen TV, a fireplace, a sofa, a coffee table, and a large window with a view.

A reception area with a blue counter, a television screen, and a modern interior design.

18. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Ally Marie

NT$4,435

NT$5,054 total

includes taxes & fees

Oct 25 - Oct 26

A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.

An outdoor patio area with stone pillars, fire pit seating, and tables.

A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows and a covered patio area.

A modern kitchen with dark wooden cabinets, a white countertop, and a black refrigerator.

19. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Central Scottsdale, 12.3 km from Mayo Clinic Scottsdale

Dana

NT$4,754

NT$5,418 total

includes taxes & fees

Oct 1 - Oct 2

A spacious lobby with a large seating area, a reception desk, and artwork on the walls.

A buffet counter with various food items, a refrigerator, and a wall-mounted clock.

20. Best Western Plus Scottsdale Thunderbird Suites

Thunderbird Industrial Airpark, 12.1 km from Mayo Clinic Scottsdale

Susan

NT$4,231

NT$4,822 total

includes taxes & fees

Oct 27 - Oct 28

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very good 1,103 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,019 reviews	View
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale	8.8 Excellent 1,864 reviews	View
Home2 Suites by Hilton Mesa Longbow, AZ	9.6 Exceptional 906 reviews	View
Comfort Suites Scottsdale Talking Stick Entertainment District	9.2 Wonderful 2,034 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Inn at Eagle Mountain

8/10 Good

"This was the perfect respite for days of appointments at Mayo."

Spark by Hilton Fountain Hills Scottsdale

10/10 Excellent

"Great parking."

Home2 Suites by Hilton Scottsdale Salt River

8/10 Good

"Quiet location and great staff."

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

10/10 Excellent

"Quality service"

Wekopa Casino Resort

10/10 Excellent

"Prompt valet, quick check-in, clean room with everything you need and a comfy bed. Convenient food/bev downstairs any time, good casino, worth the extra drive time to get there."

Great Wolf Lodge Arizona

10/10 Excellent

"Facilities are amazing for families with kids. Please note there’s no in-room safe for your money,passports belonging."

Aiden by Best Western Scottsdale North

8/10 Good

"Hot tub was not working, 11 dollars for typical breakfast that is usually free."

Fountain Park Hotel, BW Signature Collection

10/10 Excellent

"We will return to this hotel."

Hampton Inn & Suites Scottsdale at Talking Stick

10/10 Excellent

"It’s what I usually expect for a Hampton Inn. Clean, cheap, easy quiet. No surprises. The free waffles closed the deal."

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,808

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Be picky

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

4. Home2 Suites by Hilton Mesa Longbow, AZ

5. Comfort Suites Scottsdale Talking Stick Entertainment District

6. Spark by Hilton Fountain Hills Scottsdale

7. Fountain Park Hotel, BW Signature Collection

8. Wekopa Casino Resort

9. Aiden by Best Western Scottsdale North

10. Talking Stick Resort

11. Sonesta ES Suites Scottsdale Paradise Valley

12. Hyatt House North Scottsdale

13. Staybridge Suites Scottsdale - Talking Stick by IHG

14. Holiday Inn Express Scottsdale North by IHG

15. Hampton Inn & Suites Scottsdale at Talking Stick

16. Tru By Hilton Scottsdale Salt River

17. ADERO Scottsdale Resort, Autograph Collection

18. Holiday Inn & Suites Scottsdale North - Airpark by IHG

19. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

20. Best Western Plus Scottsdale Thunderbird Suites

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Inn at Eagle Mountain

Spark by Hilton Fountain Hills Scottsdale

Home2 Suites by Hilton Scottsdale Salt River

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Wekopa Casino Resort

Great Wolf Lodge Arizona

Aiden by Best Western Scottsdale North

Fountain Park Hotel, BW Signature Collection

Hampton Inn & Suites Scottsdale at Talking Stick

Frequently asked questions

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