The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A cluster of modern, multi-story buildings with a river in the foreground.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

A golf course with a pond, a clubhouse, and a hilly backdrop.

A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

1. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Andrei

NT$5,046

NT$5,761 total

includes taxes & fees

Oct 8 - Oct 9

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

A breakfast buffet area with various pastries and a sign indicating the price of a cheese danish.

2. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

Michael

NT$3,409

NT$3,885 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

A modern hotel lobby with a central bar area, seating arrangements, and a clean, contemporary design.

3. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

William

NT$3,302

NT$3,765 total

includes taxes & fees

Oct 11 - Oct 12

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.

4. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Cathleen

NT$2,685

NT$3,060 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with two beds, a TV, a desk, and a window with a view.

A modern office space with multiple desks, chairs, and a meeting area.

A pool area with a clear blue pool, lounge chairs, and a multi-story building with balconies.

A modern hotel room with a large window, a desk with a lamp, a microwave, and a chair.

5. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Peyton

NT$2,455

NT$2,803 total

includes taxes & fees

Oct 14 - Oct 15

A wooden door with a glass panel, a doormat, and a small window above it.

A modern kitchen with white cabinets, a built-in oven, and a large window.

6. Close to Hiking! Family-friendly Mesa Retreat

13.6 km from Mayo Clinic Scottsdale

NT$5,734

NT$24,943 total

includes taxes & fees

Oct 14 - Oct 15

An outdoor dining table set with chairs, string lights, and a sunset view.

A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.

A multi-story hotel with a prominent entrance, large windows, and a well-lit facade.

A modern living room with a sectional sofa, orange ottomans, a dining area, and a kitchen with a stone accent wall.

7. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Damon

NT$4,963

NT$5,671 total

includes taxes & fees

Nov 1 - Nov 2

A spacious living area with a kitchen, modern furniture, and a fireplace.

A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

8. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

NT$3,318

NT$3,788 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

A lounge area with a grand piano, blue seating, and a stone wall.

A dining area with a large table set for six, surrounded by chairs, with a view of cacti and a stone wall outside.

9. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Darrick

NT$5,232

NT$7,840 total

includes taxes & fees

Nov 1 - Nov 2

A modern infinity pool with a view of mountains and a sunset.

An outdoor seating area with fire pits and lounge chairs, surrounded by trees and a building with illuminated windows in the background.

A restaurant with high tables and booths, floral wall decorations, and a view of the mountains.

A poolside lounge with a view of a hotel building, a TV, and a bar area with a bottle of champagne.

10. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Meghan Rebbecca

NT$6,558

NT$8,387 total

includes taxes & fees

Oct 5 - Oct 6

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

A bar area with a bar counter, multiple chairs, and a sofa.

A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

11. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

cody

NT$3,213

NT$3,662 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with a bed, desk, chair, television, fireplace, and a dining area.

A hotel room with a bed, a desk with a TV, a sofa, and a coffee table.

An outdoor patio with a grill, table, and chairs.

A breakfast buffet with various food items and a coffee machine.

12. Sonesta ES Suites Scottsdale Paradise Valley

14 km from Mayo Clinic Scottsdale

Michael

NT$3,861

NT$4,400 total

includes taxes & fees

Oct 14 - Oct 15

A circular fire feature with a stone border, surrounded by a landscaped garden with cacti and shrubs, under a sunset sky.

A pool area with lounge chairs and umbrellas, surrounded by buildings with balconies and outdoor seating.

A modern bar area with seating, a digital menu display, and a beverage refrigerator.

A Courtyard by Marriott hotel with a modern design, featuring a covered entrance and stone pillars.

13. Courtyard Scottsdale Salt River

12.2 km from Mayo Clinic Scottsdale

Karl

NT$4,658

NT$5,309 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.

A hotel room with a desk, chair, television, lamp, and a framed artwork on the wall.

A hotel gym with dumbbells on racks, a bench, and a mirror.

A hotel breakfast area with a self-serve station, seating, and a trash bin.

14. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Melanie

NT$2,899

NT$3,304 total

includes taxes & fees

Nov 1 - Nov 2

A hotel dining area with a table and chairs, patterned curtains, and a view through large windows.

A building entrance with a stone facade, large glass doors, and potted plants.

A golf course with sand bunkers, a flagstick, and mountains in the background.

A hotel lobby with a bar area, seating, and a reception desk.

15. Hampton Inn & Suites Scottsdale at Talking Stick

9.1 km from Mayo Clinic Scottsdale

Mark

NT$3,898

NT$4,445 total

includes taxes & fees

Oct 11 - Oct 12

An outdoor patio area with round tables and chairs, a pool in the background, and a covered seating area.

A multi-story hotel with illuminated signage reading "Talking Stick" and "Resort".

A hotel room with a desk, a bed, a TV, a sofa, a small table, and a view of the outdoors.

A hotel room with a bed, a desk, a chair, a sofa, a small table, and a TV.

16. Staybridge Suites Scottsdale - Talking Stick by IHG

9.7 km from Mayo Clinic Scottsdale

Gentry

NT$5,264

NT$6,002 total

includes taxes & fees

Oct 26 - Oct 27

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

17. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Colleen

NT$3,898

NT$4,445 total

includes taxes & fees

Oct 25 - Oct 26

A resort with multiple buildings, a large pool area, and surrounding mountains.

A dining area with a table and chairs, a view of a cityscape, and decorative wall panels.

A dining area with a table set for six, overlooking a scenic landscape.

Three people in a swimming pool with rocks and a red umbrella in the background.

18. ADERO Scottsdale Resort, Autograph Collection

3.6 km from Mayo Clinic Scottsdale

Karen

NT$7,591

NT$9,942 total

includes taxes & fees

Oct 2 - Oct 3

A breakfast bar with a variety of baked goods and a sign indicating fresh baked items.

A reception area with a blue counter, a television screen, and a modern interior design.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.

A hotel room with a flat-screen TV, a fireplace, a sofa, a coffee table, and a large window with a view.

19. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Ally Marie

NT$4,435

NT$5,054 total

includes taxes & fees

Oct 25 - Oct 26

A spacious lobby with stone walls, comfortable seating, and a large window offering a mountain view.

A spacious living area with a large sectional sofa, wooden coffee tables, and a stone wall.

A spacious lobby with a central table set for a small gathering, flanked by seating and a modern ceiling design.

A spacious restaurant with wooden flooring, high tables, and chairs, featuring a bar area and large windows overlooking a scenic view.

20. Hilton North Scottsdale At Cavasson

13.4 km from Mayo Clinic Scottsdale

Marcos

NT$8,776

NT$10,003 total

includes taxes & fees

Oct 9 - Oct 10

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Inn at Eagle Mountain	9.0 Wonderful 1,019 reviews	View
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very good 1,103 reviews	View
Comfort Suites Scottsdale Talking Stick Entertainment District	9.2 Wonderful 2,034 reviews	View
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale	8.8 Excellent 1,864 reviews	View
Spark by Hilton Fountain Hills Scottsdale	8.8 Excellent 320 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Inn at Eagle Mountain

8/10 Good

"This was the perfect respite for days of appointments at Mayo."

Spark by Hilton Fountain Hills Scottsdale

10/10 Excellent

"Great parking."

Home2 Suites by Hilton Scottsdale Salt River

8/10 Good

"Quiet location and great staff."

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

10/10 Excellent

"Quality service"

Wekopa Casino Resort

10/10 Excellent

"Prompt valet, quick check-in, clean room with everything you need and a comfy bed. Convenient food/bev downstairs any time, good casino, worth the extra drive time to get there."

Great Wolf Lodge Arizona

10/10 Excellent

"Facilities are amazing for families with kids. Please note there’s no in-room safe for your money,passports belonging."

Aiden by Best Western Scottsdale North

8/10 Good

"Hot tub was not working, 11 dollars for typical breakfast that is usually free."

Fountain Park Hotel, BW Signature Collection

10/10 Excellent

"We will return to this hotel."

Hampton Inn & Suites Scottsdale at Talking Stick

10/10 Excellent

"It’s what I usually expect for a Hampton Inn. Clean, cheap, easy quiet. No surprises. The free waffles closed the deal."

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,803

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Our top choices for Mayo Clinic Scottsdale hotels

1. Inn at Eagle Mountain

2. Sonesta Select Scottsdale at Mayo Clinic Campus

3. Comfort Suites Scottsdale Talking Stick Entertainment District

4. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

5. Spark by Hilton Fountain Hills Scottsdale

6. Close to Hiking! Family-friendly Mesa Retreat

7. Home2 Suites by Hilton Mesa Longbow, AZ

8. Fountain Park Hotel, BW Signature Collection

9. Wekopa Casino Resort

10. Talking Stick Resort

11. Aiden by Best Western Scottsdale North

12. Sonesta ES Suites Scottsdale Paradise Valley

13. Courtyard Scottsdale Salt River

14. Holiday Inn Express Scottsdale North by IHG

15. Hampton Inn & Suites Scottsdale at Talking Stick

16. Staybridge Suites Scottsdale - Talking Stick by IHG

17. Tru By Hilton Scottsdale Salt River

18. ADERO Scottsdale Resort, Autograph Collection

19. Holiday Inn & Suites Scottsdale North - Airpark by IHG

20. Hilton North Scottsdale At Cavasson

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Inn at Eagle Mountain

Spark by Hilton Fountain Hills Scottsdale

Home2 Suites by Hilton Scottsdale Salt River

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Wekopa Casino Resort

Great Wolf Lodge Arizona

Aiden by Best Western Scottsdale North

Fountain Park Hotel, BW Signature Collection

Hampton Inn & Suites Scottsdale at Talking Stick

Frequently asked questions

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