The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

A breakfast buffet area with various pastries and a sign indicating the price of a cheese danish.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

louis

NT$3,195

NT$3,641 total

includes taxes & fees

Nov 22 - Nov 23

A cluster of modern, multi-story buildings with a river in the foreground.

A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

A dining area with a glass table, wooden chairs, and potted plants.

A golf course with a pond, a clubhouse, and a hilly backdrop.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Stephanie

NT$4,168

NT$4,758 total

includes taxes & fees

Oct 28 - Oct 29

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

A modern hotel lobby with a central bar area, seating arrangements, and a clean, contemporary design.

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

3. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

LAURA

NT$3,550

NT$4,048 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor dining table set with chairs, string lights, and a sunset view.

A modern living room with a sectional sofa, orange ottomans, a dining area, and a kitchen with a stone accent wall.

A multi-story hotel with a prominent entrance, large windows, and a well-lit facade.

A modern lobby with a seating area, a kitchen, and a reception desk.

4. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Claudia

NT$4,545

NT$5,193 total

includes taxes & fees

Nov 22 - Nov 23

A modern hotel with a brick facade, large windows, and a covered entrance area.

A hotel room with a desk, two beds, a TV, and a large window.

A modern lobby with a sectional sofa, a round coffee table, and a mural on the wall.

A modern bar area with a wooden ceiling, bar stools, and a counter with a digital screen.

5. Springhill Suites Phoenix Scottsdale Marriott

18.2 km from Mayo Clinic Scottsdale

Lucinda

NT$3,569

NT$4,068 total

includes taxes & fees

Nov 22 - Nov 23

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

6. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Joseph

NT$2,882

NT$3,285 total

includes taxes & fees

Oct 26 - Oct 27

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

A multi-story hotel with a central courtyard, parking, and a mountainous backdrop.

A bar area with a long counter, multiple stools, and overhead pendant lighting.

A spacious living area with a sofa, chairs, a coffee table, and a TV mounted on the wall.

7. Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Deborah

NT$4,401

NT$5,016 total

includes taxes & fees

Nov 15 - Nov 16

A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.

A modern lobby with a brick wall, seating area, and a flat-screen TV.

A hotel room with two beds, a TV, a desk, a chair, and a view of palm trees.

A restaurant with multiple round tables and bar stools, a self-service beverage dispenser, and a television mounted on the wall.

8. Hyatt Place Phoenix/Mesa

17.8 km from Mayo Clinic Scottsdale

Laura

NT$4,401

NT$5,029 total

includes taxes & fees

Nov 22 - Nov 23

A modern infinity pool with a view of mountains and a sunset.

A poolside lounge with a view of a hotel building, a TV, and a bar area with a bottle of champagne.

An outdoor seating area with fire pits and lounge chairs, surrounded by trees and a building with illuminated windows in the background.

A modern bar area with a unique ceiling design, a bar counter with multiple screens, and a patterned carpet.

9. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Jessica

NT$5,194

NT$6,851 total

includes taxes & fees

Nov 22 - Nov 23

A restaurant setting with round tables, chairs, and empty wine glasses.

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.

10. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

Marie

NT$3,335

NT$3,801 total

includes taxes & fees

Oct 26 - Oct 27

A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and a television screen.

A bar area with multiple seating options, a bar counter, and a television screen displaying sports.

A spacious hotel lobby with a reception desk, seating areas, and a view of the dining and kitchen areas.

A multi-story hotel with a flat roof and balconies, surrounded by well-maintained grass and trees.

11. Embassy Suites by Hilton Phoenix Scottsdale

17.8 km from Mayo Clinic Scottsdale

Matthew

NT$4,785

NT$5,411 total

includes taxes & fees

Nov 22 - Nov 23

A spacious living area with a kitchen, modern furniture, and a fireplace.

A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

12. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

NT$3,880

NT$4,429 total

includes taxes & fees

Oct 26 - Oct 27

A hotel room with two beds, a desk, a lamp, and artwork on the wall.

A modern hotel room with a large window, a desk with a lamp, a chair, and a television.

A reception area with a wooden counter, a large abstract painting above it, and a green carpet. There are shelves with bottled water and snacks on the right.

A hotel entrance with a sign reading 'spark by Hilton' and a covered outdoor area with palm trees.

13. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Herbert M Beatty

NT$2,647

NT$3,022 total

includes taxes & fees

Nov 3 - Nov 4

A hotel with a modern design, featuring a curved roof, large windows, and a landscaped entrance area with palm trees and shrubs.

A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.

A buffet with labeled trays of turkey sausage and cookies.

A swimming pool with lounge chairs and umbrellas, surrounded by a fence and palm trees.

14. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Melanie

NT$3,195

NT$3,641 total

includes taxes & fees

Nov 23 - Nov 24

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.

15. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Colleen

NT$3,713

NT$4,234 total

includes taxes & fees

Nov 8 - Nov 9

A hotel dining area with a table and chairs, patterned curtains, and a view through large windows.

A hotel lobby with a bar area, seating, and a reception desk.

A building entrance with a stone facade, large glass doors, and potted plants.

A golf course with sand bunkers, a flagstick, and mountains in the background.

16. Hampton Inn & Suites Scottsdale at Talking Stick

9.1 km from Mayo Clinic Scottsdale

Cynthia

NT$3,852

NT$4,392 total

includes taxes & fees

Nov 22 - Nov 23

A modern hotel with a flat roof, multiple floors, and a sign indicating 'Springhill Suites'.

A modern hotel lobby with multiple seating areas, a reception desk, and a large flat-screen TV mounted on the wall.

A hotel room with a wooden desk, a flat-screen TV, a sofa, and a tray table with a book.

17. SpringHill Suites Scottsdale North

13.8 km from Mayo Clinic Scottsdale

Charlene

NT$3,852

NT$4,355 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

A bar area with a long counter, multiple bar stools, and overhead lighting.

A hotel room with two beds, a desk, a sofa, and a TV.

A spacious living area with a sofa, armchairs, and a coffee table. There is a TV mounted on the wall and a balcony with outdoor seating.

18. Hyatt Place Scottsdale - North

14.1 km from Mayo Clinic Scottsdale

Ted

NT$5,249

NT$5,982 total

includes taxes & fees

Nov 22 - Nov 23

A spacious lobby with a modern staircase, a comfortable seating area, and a large window providing natural light.

A hotel pool area with two hot tubs and lounge chairs.

A hotel room with two beds, a nightstand, a lamp, and framed pictures on the wall.

A patio area with wicker furniture, a large umbrella, and a pool in the background.

19. Sleep Inn North Scottsdale near Mayo Clinic

Paradise Valley Village, 13.5 km from Mayo Clinic Scottsdale

Margret

NT$3,575

NT$4,042 total

includes taxes & fees

Nov 22 - Nov 23

A swimming pool with a bridge structure, surrounded by buildings with outdoor seating and a clear sky.

A breakfast bar with a variety of baked goods and a sign indicating fresh baked items.

A reception area with a blue counter, a television screen, and a modern interior design.

A hotel room with a sofa, a chair, a desk with a television, a lamp, and a framed artwork on the wall.

20. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Ally Marie

NT$4,140

NT$4,719 total

includes taxes & fees

Nov 22 - Nov 23

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very good 1,093 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,035 reviews	View
Comfort Suites Scottsdale Talking Stick Entertainment District	9.2 Wonderful 2,058 reviews	View
Home2 Suites by Hilton Mesa Longbow, AZ	9.6 Exceptional 921 reviews	View
Springhill Suites Phoenix Scottsdale Marriott	9.4 Exceptional 456 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Staybridge Suites Scottsdale - Talking Stick by IHG

10/10 Excellent

"Very convenient and enjoyable location"

Sonesta Select Scottsdale at Mayo Clinic Campus

10/10 Excellent

"Location is wonderful for appointments I have with Mayo Clinic or hospital"

Comfort Suites Scottsdale Talking Stick Entertainment District

10/10 Excellent

"Staff great Reasonable rates and location was perfect."

ADERO Scottsdale Resort, Autograph Collection

10/10 Excellent

"We had a great weekend at Adero, a lovely location that is in the foothills and very quiet. We had a beautiful view from our room and enjoyed playing tennis both days. The staff was really helpful and friendly. We would definitely recommend!"

Inn at Eagle Mountain

8/10 Good

"I think I was able to get one of the last rooms same day....beautiful room, comfortable and spacious, bathroom as well. My view was the parking lot, but next time I will book in advance for hopefully a valley view. Friendly young front desk rep offering wine tasting at that time."

Aiden by Best Western Scottsdale North

8/10 Good

"Room was not done at check in"

Sonesta Simply Suites Phoenix Scottsdale

10/10 Excellent

"Great price! It was actually a suitet with a kitchenette although I didn't use it. I would definitely stay there again if I was in the area!"

Fountain Park Hotel, BW Signature Collection

10/10 Excellent

"Everything was in order. No issues, helpful staff and a good location"

Wekopa Casino Resort

10/10 Excellent

"We had fun at the slot machines over the Fri-Sat weekend. Hotel is clean and decent. They had healthy options at the fast food. We'll be back."

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$3,022

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. Comfort Suites Scottsdale Talking Stick Entertainment District

4. Home2 Suites by Hilton Mesa Longbow, AZ

5. Springhill Suites Phoenix Scottsdale Marriott

6. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

7. Hyatt House North Scottsdale

8. Hyatt Place Phoenix/Mesa

9. Talking Stick Resort

10. Aiden by Best Western Scottsdale North

11. Embassy Suites by Hilton Phoenix Scottsdale

12. Fountain Park Hotel, BW Signature Collection

13. Spark by Hilton Fountain Hills Scottsdale

14. Holiday Inn Express Scottsdale North by IHG

15. Tru By Hilton Scottsdale Salt River

16. Hampton Inn & Suites Scottsdale at Talking Stick

17. SpringHill Suites Scottsdale North

18. Hyatt Place Scottsdale - North

19. Sleep Inn North Scottsdale near Mayo Clinic

20. Holiday Inn & Suites Scottsdale North - Airpark by IHG

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Staybridge Suites Scottsdale - Talking Stick by IHG

Sonesta Select Scottsdale at Mayo Clinic Campus

Comfort Suites Scottsdale Talking Stick Entertainment District

ADERO Scottsdale Resort, Autograph Collection

Inn at Eagle Mountain

Aiden by Best Western Scottsdale North

Sonesta Simply Suites Phoenix Scottsdale

Fountain Park Hotel, BW Signature Collection

Wekopa Casino Resort

Frequently asked questions

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