The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

Michael

NT$3,063

NT$3,491 total

includes taxes & fees

Oct 1 - Oct 2

A cluster of modern, multi-story buildings with a river in the foreground.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

A dining area with a glass table, wooden chairs, and potted plants.

A golf course with a pond, a clubhouse, and a hilly backdrop.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Andrei

NT$5,337

NT$6,093 total

includes taxes & fees

Oct 7 - Oct 8

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Cathleen

NT$2,674

NT$3,048 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor dining table set with chairs, string lights, and a sunset view.

A multi-story hotel with a prominent entrance, large windows, and a well-lit facade.

A modern living room with a sectional sofa, orange ottomans, a dining area, and a kitchen with a stone accent wall.

A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.

4. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Damon

NT$5,221

NT$5,966 total

includes taxes & fees

Oct 15 - Oct 16

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

A modern hotel lobby with a central bar area, seating arrangements, and a clean, contemporary design.

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

5. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

William

NT$3,302

NT$3,765 total

includes taxes & fees

Oct 11 - Oct 12

A wooden door with a glass panel, a doormat, and a small window above it.

A modern kitchen with white cabinets, a built-in oven, and a large window.

A bedroom with a desk, a bed, a ceiling fan, and a window with blinds.

6. Close to Hiking! Family-friendly Mesa Retreat

13.6 km from Mayo Clinic Scottsdale

NT$5,720

NT$24,884 total

includes taxes & fees

Oct 4 - Oct 5

A spacious living area with a kitchen, modern furniture, and a fireplace.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.

A spacious lobby with a high ceiling, modern chandeliers, a fire feature, and a large TV screen.

7. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

NT$2,999

NT$3,424 total

includes taxes & fees

Oct 1 - Oct 2

A hotel room with two beds, a TV, a desk, and a window with a view.

A pool area with a clear blue pool, lounge chairs, and a multi-story building with balconies.

A modern hotel room with a large window, a desk with a lamp, a microwave, and a chair.

A modern office space with multiple desks, chairs, and a meeting area.

8. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Jim

NT$2,450

NT$2,797 total

includes taxes & fees

Oct 8 - Oct 9

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

A golf course with a mountain backdrop, surrounded by desert vegetation.

A lounge area with a grand piano, blue seating, and a stone wall.

9. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Darrick

NT$3,505

NT$5,875 total

includes taxes & fees

Oct 4 - Oct 5

A modern infinity pool with a view of mountains and a sunset.

A poolside lounge with a view of a hotel building, a TV, and a bar area with a bottle of champagne.

An outdoor seating area with fire pits and lounge chairs, surrounded by trees and a building with illuminated windows in the background.

A modern bar area with a unique ceiling design, a bar counter with multiple screens, and a patterned carpet.

10. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Meghan Rebbecca

NT$6,532

NT$8,354 total

includes taxes & fees

Oct 5 - Oct 6

A hotel room with a bed, desk, chair, television, fireplace, and a dining area.

A breakfast buffet with various food items and a coffee machine.

A hotel room with a bed, a desk with a TV, a sofa, and a coffee table.

An outdoor patio with a grill, table, and chairs.

11. Sonesta ES Suites Scottsdale Paradise Valley

14 km from Mayo Clinic Scottsdale

Michael

NT$3,861

NT$4,400 total

includes taxes & fees

Oct 14 - Oct 15

A landscaped garden with a fountain, palm trees, and a building with a red roof.

A courtyard with palm trees, a fountain, and a bench.

A modern kitchen with a glass dining table, bar stools, and a built-in island with a microwave and oven.

A tranquil pond with a fountain, surrounded by lush greenery and a large building in the background.

12. Westgate Painted Mountain Golf Resort

17.4 km from Mayo Clinic Scottsdale

Tammie

NT$3,146

NT$3,595 total

includes taxes & fees

Oct 1 - Oct 2

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

A multi-story hotel with a central courtyard, parking, and a mountainous backdrop.

A reception area with marble reception desks, a wooden ceiling, and a wall-mounted refrigerator.

A bar area with a long counter, multiple stools, and overhead pendant lighting.

13. Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Slyqavious

NT$4,290

NT$4,890 total

includes taxes & fees

Oct 25 - Oct 26

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A bar area with a bar counter, multiple chairs, and a sofa.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.

14. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

cody

NT$2,999

NT$3,418 total

includes taxes & fees

Oct 1 - Oct 2

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

A bar area with a long counter, multiple bar stools, and overhead lighting.

A spacious living area with a sofa, armchairs, and a coffee table. There is a TV mounted on the wall and a balcony with outdoor seating.

A multi-story hotel with a parking lot and a road leading to a roundabout.

15. Hyatt Place North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Ana

NT$4,119

NT$4,694 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.

A swimming pool with lounge chairs and umbrellas, surrounded by a fence and palm trees.

A hotel room with a desk, chair, television, lamp, and a framed artwork on the wall.

A hotel breakfast area with a self-serve station, seating, and a trash bin.

16. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Melanie

NT$2,797

NT$3,187 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor patio area with round tables and chairs, a pool in the background, and a covered seating area.

A multi-story hotel with illuminated signage reading "Talking Stick" and "Resort".

A hotel reception area with a large bridge mural, a reception desk, and a snack bar.

A hotel room with a bed, a desk, a chair, a sofa, a small table, and a TV.

17. Staybridge Suites Scottsdale - Talking Stick by IHG

9.7 km from Mayo Clinic Scottsdale

Gentry

NT$5,232

NT$5,966 total

includes taxes & fees

Oct 1 - Oct 2

A hotel dining area with a table and chairs, patterned curtains, and a view through large windows.

A hotel room with a large window, a desk, a bed, a TV, and a chair.

A golf course with sand bunkers, a flagstick, and mountains in the background.

A building entrance with a stone facade, large glass doors, and potted plants.

18. Hampton Inn & Suites Scottsdale at Talking Stick

9.1 km from Mayo Clinic Scottsdale

Mark

NT$3,883

NT$4,427 total

includes taxes & fees

Oct 25 - Oct 26

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.

19. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Colleen

NT$3,883

NT$4,427 total

includes taxes & fees

Oct 25 - Oct 26

A resort with multiple buildings, a large pool area, and surrounding mountains.

Three people in a swimming pool with rocks and a red umbrella in the background.

A dining area with a table set for six, overlooking a scenic landscape.

An outdoor wedding reception with round tables set with white chairs, floral centerpieces, and a view of the city in the background.

20. ADERO Scottsdale Resort, Autograph Collection

3.6 km from Mayo Clinic Scottsdale

Karen

NT$7,373

NT$9,688 total

includes taxes & fees

Oct 2 - Oct 3

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very good 1,102 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,018 reviews	View
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale	8.8 Excellent 1,864 reviews	View
Home2 Suites by Hilton Mesa Longbow, AZ	9.6 Exceptional 906 reviews	View
Comfort Suites Scottsdale Talking Stick Entertainment District	9.2 Wonderful 2,034 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Spark by Hilton Fountain Hills Scottsdale

8/10 Good

"The only reason for the 4 star was the bed was a bit to hard for my back and the breakfast was a bit limited. Other than that the hotel was clean and the and the rooms were nice. Good bargain overall."

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

10/10 Excellent

"Quality service"

Wekopa Casino Resort

10/10 Excellent

"Prompt valet, quick check-in, clean room with everything you need and a comfy bed. Convenient food/bev downstairs any time, good casino, worth the extra drive time to get there."

Great Wolf Lodge Arizona

10/10 Excellent

"Facilities are amazing for families with kids. Please note there’s no in-room safe for your money,passports belonging."

Aiden by Best Western Scottsdale North

8/10 Good

"Hot tub was not working, 11 dollars for typical breakfast that is usually free."

Fountain Park Hotel, BW Signature Collection

10/10 Excellent

"We will return to this hotel."

Hampton Inn & Suites Scottsdale at Talking Stick

10/10 Excellent

"It’s what I usually expect for a Hampton Inn. Clean, cheap, easy quiet. No surprises. The free waffles closed the deal."

Sonesta Simply Suites Phoenix Scottsdale

10/10 Excellent

"The microwave didn't have a rotating plate. There was a coffee pot but no coffee. Only one cup for two people. One bowl, no plates. Therefore, kitchen amenities were incomplete."

Staybridge Suites Scottsdale - Talking Stick by IHG

10/10 Excellent

"The breakfast was fantastic!!"

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 21 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 21 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,797

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

4. Home2 Suites by Hilton Mesa Longbow, AZ

5. Comfort Suites Scottsdale Talking Stick Entertainment District

6. Close to Hiking! Family-friendly Mesa Retreat

7. Fountain Park Hotel, BW Signature Collection

8. Spark by Hilton Fountain Hills Scottsdale

9. Wekopa Casino Resort

10. Talking Stick Resort

11. Sonesta ES Suites Scottsdale Paradise Valley

12. Westgate Painted Mountain Golf Resort

13. Hyatt House North Scottsdale

14. Aiden by Best Western Scottsdale North

15. Hyatt Place North Scottsdale

16. Holiday Inn Express Scottsdale North by IHG

17. Staybridge Suites Scottsdale - Talking Stick by IHG

18. Hampton Inn & Suites Scottsdale at Talking Stick

19. Tru By Hilton Scottsdale Salt River

20. ADERO Scottsdale Resort, Autograph Collection

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Spark by Hilton Fountain Hills Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Wekopa Casino Resort

Great Wolf Lodge Arizona

Aiden by Best Western Scottsdale North

Fountain Park Hotel, BW Signature Collection

Hampton Inn & Suites Scottsdale at Talking Stick

Sonesta Simply Suites Phoenix Scottsdale

Staybridge Suites Scottsdale - Talking Stick by IHG

Frequently asked questions

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