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Our top choices for Mayo Clinic Scottsdale hotels

A cluster of modern, multi-story buildings with a river in the foreground.
A dining area with a glass table, wooden chairs, and potted plants.
An outdoor patio with a stone wall, wooden pergola, and a cactus.
A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

1. Inn at Eagle Mountain

Inn at Eagle Mountain
3.1 km from Mayo Clinic Scottsdale
United States
Shelby
NT$4,222
NT$4,820 total
includes taxes & fees
Oct 25 - Oct 26
Inn at Eagle Mountain
A hotel lobby with a reception desk, seating area, and a large wall mural.
A hotel room with two beds, a desk, a lamp, and a window with curtains.
A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.
A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

2. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale
United States
Paul
NT$2,686
NT$3,062 total
includes taxes & fees
Oct 25 - Oct 26
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
A hotel room with two beds, a desk with a chair, a TV, and a lamp.
Pool
A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.
A modern hotel lobby with a central bar area, seating arrangements, and a clean, contemporary design.

3. Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District
9.6 km from Mayo Clinic Scottsdale
United States
LAURA
NT$3,477
NT$3,964 total
includes taxes & fees
Oct 25 - Oct 26
Comfort Suites Scottsdale Talking Stick Entertainment District
An outdoor dining table set with chairs, string lights, and a sunset view.
A multi-story hotel with a prominent entrance, large windows, and a well-lit facade.
A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.
A modern lobby with a seating area, a kitchen, and a reception desk.

4. Home2 Suites by Hilton Mesa Longbow, AZ

Home2 Suites by Hilton Mesa Longbow, AZ
14.8 km from Mayo Clinic Scottsdale
United States
Damon
NT$4,966
NT$5,674 total
includes taxes & fees
Nov 1 - Nov 2
Home2 Suites by Hilton Mesa Longbow, AZ
A wooden door with a glass panel, a doormat, and a small window above it.
Front of property
A bedroom with a desk, a bed, a ceiling fan, and a window with blinds.
Interior

5. Close to Hiking! Family-friendly Mesa Retreat

Close to Hiking! Family-friendly Mesa Retreat
13.6 km from Mayo Clinic Scottsdale
NT$5,746
NT$24,996 total
includes taxes & fees
Oct 26 - Oct 27
Close to Hiking! Family-friendly Mesa Retreat
A spacious living area with a kitchen, modern furniture, and a fireplace.
A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.
A modern lobby with a pool view, orange seating, and a wooden accent wall.
A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

6. Fountain Park Hotel, BW Signature Collection

Fountain Park Hotel, BW Signature Collection
7.3 km from Mayo Clinic Scottsdale
United States
Guadalupe
NT$3,480
NT$3,973 total
includes taxes & fees
Oct 15 - Oct 16
Fountain Park Hotel, BW Signature Collection
A hotel room with two beds, a TV, a desk, and a window with a view.
A hotel room with two beds, a desk, a TV, and a balcony with a view.
A pool area with a clear blue pool, lounge chairs, and a multi-story building with balconies.
A modern office space with multiple desks, chairs, and a meeting area.

7. Spark by Hilton Fountain Hills Scottsdale

Spark by Hilton Fountain Hills Scottsdale
7.6 km from Mayo Clinic Scottsdale
United States
Herlyn
NT$2,853
NT$3,258 total
includes taxes & fees
Oct 20 - Oct 21
Spark by Hilton Fountain Hills Scottsdale
A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.
A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.
A bar area with a bar counter, multiple chairs, and a sofa.
A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

8. Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North
8.7 km from Mayo Clinic Scottsdale
United States
PATRICK
NT$3,266
NT$3,722 total
includes taxes & fees
Oct 26 - Oct 27
Aiden by Best Western Scottsdale North
A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.
A reception area with marble reception desks, a wooden ceiling, and a wall-mounted refrigerator.
A multi-story hotel with a central courtyard, parking, and a mountainous backdrop.
A bar area with a long counter, multiple stools, and overhead pendant lighting.

9. Hyatt House North Scottsdale

Hyatt House North Scottsdale
14.1 km from Mayo Clinic Scottsdale
United States
Slyqavious
NT$4,310
NT$4,912 total
includes taxes & fees
Oct 21 - Oct 22
Hyatt House North Scottsdale
A landscaped garden with a fountain, palm trees, and a building with a red roof.
A pool area with a rock formation, palm trees, and lounge chairs.
A modern kitchen with a glass dining table, bar stools, and a built-in island with a microwave and oven.
A tranquil pond with a fountain, surrounded by lush greenery and a large building in the background.

10. Westgate Painted Mountain Golf Resort

Westgate Painted Mountain Golf Resort
17.4 km from Mayo Clinic Scottsdale
United States
Tammie
NT$3,267
NT$3,733 total
includes taxes & fees
Oct 27 - Oct 28
Westgate Painted Mountain Golf Resort
A modern infinity pool with a view of mountains and a sunset.
A modern bar area with a unique ceiling design, a bar counter with multiple screens, and a patterned carpet.
An outdoor seating area with fire pits and lounge chairs, surrounded by trees and a building with illuminated windows in the background.
A restaurant with high tables and booths, floral wall decorations, and a view of the mountains.

11. Talking Stick Resort

Talking Stick Resort
8.8 km from Mayo Clinic Scottsdale
United States
Jessica
NT$6,780
NT$8,641 total
includes taxes & fees
Nov 8 - Nov 9
Talking Stick Resort
A hotel room with a bed, desk, chair, television, fireplace, and a dining area.
An outdoor patio with a grill, table, and chairs.
A reception area with a counter, two armchairs, and a round table.
A hotel room with a bed, a desk with a TV, a sofa, and a coffee table.

12. Sonesta ES Suites Scottsdale Paradise Valley

Sonesta ES Suites Scottsdale Paradise Valley
14 km from Mayo Clinic Scottsdale
United States
Eriel
NT$3,799
NT$4,330 total
includes taxes & fees
Oct 25 - Oct 26
Sonesta ES Suites Scottsdale Paradise Valley
A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.
A hotel room with a desk, chair, television, lamp, and a framed artwork on the wall.
A swimming pool with lounge chairs and umbrellas, surrounded by a fence and palm trees.
A hotel breakfast area with a self-serve station, seating, and a trash bin.

13. Holiday Inn Express Scottsdale North by IHG

Holiday Inn Express Scottsdale North by IHG
Central Scottsdale, 12 km from Mayo Clinic Scottsdale
United States
Linnette
NT$3,352
NT$3,820 total
includes taxes & fees
Oct 26 - Oct 27
Holiday Inn Express Scottsdale North by IHG
An outdoor patio area with stone pillars, a fire pit, and seating arrangements.
A lounge area with a grand piano, blue seating, and a stone wall.
A dining area with a large table set for six, surrounded by chairs, with a view of cacti and a stone wall outside.
A golf course with a mountain backdrop, surrounded by desert vegetation.

14. Wekopa Casino Resort

Wekopa Casino Resort
10.3 km from Mayo Clinic Scottsdale
United States
jennifer
NT$5,848
NT$7,620 total
includes taxes & fees
Nov 8 - Nov 9
Wekopa Casino Resort
A modern bathroom with a bathtub, toilet, and sink. It includes grab bars and a shower area.
A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.
An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.
A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

15. Tru By Hilton Scottsdale Salt River

Tru By Hilton Scottsdale Salt River
8.9 km from Mayo Clinic Scottsdale
United States
Colleen
NT$3,663
NT$4,177 total
includes taxes & fees
Nov 8 - Nov 9
Tru By Hilton Scottsdale Salt River
An outdoor patio area with round tables and chairs, a pool in the background, and a covered seating area.
A hotel room with a desk, a bed, a TV, a sofa, a small table, and a view of the outdoors.
A multi-story hotel with illuminated signage reading "Talking Stick" and "Resort".
A hotel room with a bed, a desk, a chair, a sofa, a small table, and a TV.

16. Staybridge Suites Scottsdale - Talking Stick by IHG

Staybridge Suites Scottsdale - Talking Stick by IHG
9.7 km from Mayo Clinic Scottsdale
United States
Gentry
NT$5,267
NT$6,006 total
includes taxes & fees
Oct 26 - Oct 27
Staybridge Suites Scottsdale - Talking Stick by IHG
A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.
A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows and a covered patio area.
A modern kitchen with dark wooden cabinets, a white countertop, and a black refrigerator.
An outdoor patio area with stone pillars, fire pit seating, and tables.

17. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard
Central Scottsdale, 12.3 km from Mayo Clinic Scottsdale
United States
Dana
NT$5,183
NT$5,907 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard
An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.
A multi-story hotel with a parking lot and a road leading to a roundabout.
A spacious living area with a sofa, armchairs, and a coffee table. There is a TV mounted on the wall and a balcony with outdoor seating.
A hotel room with two beds, a desk, a sofa, and a TV.

18. Hyatt Place Scottsdale - North

Hyatt Place Scottsdale - North
14.1 km from Mayo Clinic Scottsdale
United States
Ted
NT$4,629
NT$5,276 total
includes taxes & fees
Oct 25 - Oct 26
Hyatt Place Scottsdale - North
A hotel dining area with a table and chairs, patterned curtains, and a view through large windows.
A hotel lobby with a bar area, seating, and a reception desk.
A hotel room with a large window, a desk, a bed, a TV, and a chair.
A golf course with sand bunkers, a flagstick, and mountains in the background.

19. Hampton Inn & Suites Scottsdale at Talking Stick

Hampton Inn & Suites Scottsdale at Talking Stick
9.1 km from Mayo Clinic Scottsdale
United States
Mark
NT$3,636
NT$4,146 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn & Suites Scottsdale at Talking Stick
A breakfast bar with a variety of baked goods and a sign indicating fresh baked items.
A hotel room with a sofa, a chair, a desk with a television, a lamp, and a framed artwork on the wall.
A reception area with a blue counter, a television screen, and a modern interior design.
A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.

20. Holiday Inn & Suites Scottsdale North - Airpark by IHG

Holiday Inn & Suites Scottsdale North - Airpark by IHG
9.7 km from Mayo Clinic Scottsdale
United States
Ally Marie
NT$5,140
NT$5,858 total
includes taxes & fees
Oct 16 - Oct 17
Holiday Inn & Suites Scottsdale North - Airpark by IHG
View all properties

Top Mayo Clinic Scottsdale Hotel Reviews

Staybridge Suites Scottsdale - Talking Stick by IHG

Staybridge Suites Scottsdale - Talking Stick by IHG

8/10 Good
"All was clean."
david 6-night trip
Posted 4 hours ago
Staybridge Suites Scottsdale - Talking Stick by IHG
Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North

8/10 Good
"."
Jorge Cordova 1-night trip
Posted 9 hours ago
Aiden by Best Western Scottsdale North
Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District

10/10 Excellent
"Very clean, looks pretty new. Great breakfast in the morning! Super nice and fast check in."
Pamela 1-night trip
Posted 22 hours ago
Comfort Suites Scottsdale Talking Stick Entertainment District
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

8/10 Good
"It’s a good value for the cost."
Susan 3-night trip
Posted 23 hours ago
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
Fountain Park Hotel, BW Signature Collection

Fountain Park Hotel, BW Signature Collection

8/10 Good
"The property location is beautiful overlooking fountain park. The location was well kept; the pool was clean and inviting. Staff was friendly and helpful. You do need to be careful in the night we saw a pack of Javalinas, they were around 20. the only thing I have a complaint is the breakfast hours. The breakfast is in a room where they keep lock and the hours are 7am-9am, would of appreciated if they were earlier in morning. Had various appt that made it difficult to partake. And in the rooms, there is coffee but no tea bags."
Berenice 3-night trip
Posted 1 day ago
Fountain Park Hotel, BW Signature Collection
Wekopa Casino Resort

Wekopa Casino Resort

10/10 Excellent
"The hotel staff was very accommodating and helped us check in a little early as we had spa appointments. The beds were comfortable. The room is spacious. The bathroom products have a slight scent that was very pleasing and not overwhelming. There are numerous places to eat - from grab and go to a fine dining restaurant. We had dinner and breakfast in the new Sports Entertainment restaurant, and both meals were very good. This was great for a "staycation" - spa treatments, meal, bingo and gambling. It was raining so we did not try the pool, but it looked inviting."
Cynthia 1-night trip
Posted 1 day ago
Wekopa Casino Resort
Hampton Inn & Suites Scottsdale at Talking Stick

Hampton Inn & Suites Scottsdale at Talking Stick

10/10 Excellent
"Love it here super clean and friendly. especially the white guy at night he was supper nice and helpful."
Lucianna 1-night trip
Posted 3 days ago
Hampton Inn & Suites Scottsdale at Talking Stick
Inn at Eagle Mountain

Inn at Eagle Mountain

10/10 Excellent
"Wonderful staff!!"
Richard 2-night trip
Posted 4 days ago
Inn at Eagle Mountain

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?
Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Mayo Clinic Scottsdale?
Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.
How many hotels will I be able to find close to Mayo Clinic Scottsdale?
Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.
Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?
To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.
What can I see and do near Mayo Clinic Scottsdale?
You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

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