The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

louis

NT$3,520 total

includes taxes & fees

Nov 22 - Nov 23

A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Jose Jr

NT$5,836 total

includes taxes & fees

Nov 18 - Nov 19

A modern infinity pool with a view of mountains and a sunset.

3. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Jessica

NT$5,586 total

includes taxes & fees

Nov 22 - Nov 23

A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.

4. Hyatt Place Phoenix/Mesa

17.8 km from Mayo Clinic Scottsdale

Laura

NT$3,792 total

includes taxes & fees

Nov 22 - Nov 23

A modern kitchen with dark cabinetry, a wooden island, stainless steel appliances, and pendant lighting.

5. Close to Hiking! Family-friendly Mesa Retreat

13.6 km from Mayo Clinic Scottsdale

NT$26,699 total

includes taxes & fees

Nov 29 - Nov 30

An outdoor dining table set with chairs, string lights, and a sunset view.

6. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Claudia

NT$5,233 total

includes taxes & fees

Nov 22 - Nov 23

A modern dining area with multiple tables and chairs, a fireplace, and a television mounted on the wall.

7. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

LAURA

NT$3,877 total

includes taxes & fees

Nov 29 - Nov 30

A hotel room with two beds, a television, a desk with a lamp, and artwork on the wall.

8. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Herbert M Beatty

NT$3,045 total

includes taxes & fees

Nov 16 - Nov 17

A modern hotel with a brick facade, large windows, and a covered entrance area.

9. Springhill Suites Phoenix Scottsdale Marriott

18.2 km from Mayo Clinic Scottsdale

Lucinda

NT$3,787 total

includes taxes & fees

Nov 22 - Nov 23

A spacious living area with a kitchen, modern furniture, and a fireplace.

10. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Laura

NT$4,464 total

includes taxes & fees

Nov 29 - Nov 30

A restaurant setting with round tables, chairs, and empty wine glasses.

11. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

Marie

NT$3,682 total

includes taxes & fees

Nov 22 - Nov 23

A hotel lobby with a reception desk, seating area, and a large wall mural.

12. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Kristle

NT$3,819 total

includes taxes & fees

Nov 23 - Nov 24

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

13. Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Chantella

NT$5,055 total

includes taxes & fees

Nov 15 - Nov 16

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

14. Hyatt Place Scottsdale - North

14.1 km from Mayo Clinic Scottsdale

Ted

NT$4,886 total

includes taxes & fees

Nov 22 - Nov 23

A swimming pool with people on inflatable floats, lounge chairs, and umbrellas in the background.

15. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Joshua

NT$6,045 total

includes taxes & fees

Nov 16 - Nov 17

An outdoor seating area with fire pit, red Adirondack chairs, and a covered patio with string lights.

16. Home2 Suites by Hilton Scottsdale North

15 km from Mayo Clinic Scottsdale

Susan

NT$4,424 total

includes taxes & fees

Nov 29 - Nov 30

A Courtyard by Marriott hotel with a landscaped entrance featuring a small waterfall and rock formations.

17. Courtyard by Marriott Scottsdale North

13.6 km from Mayo Clinic Scottsdale

Katie

NT$4,073 total

includes taxes & fees

Nov 22 - Nov 23

A circular fire feature with a stone border, surrounded by a landscaped garden with cacti and shrubs, under a sunset sky.

18. Courtyard Scottsdale Salt River

12.2 km from Mayo Clinic Scottsdale

Karl

NT$4,424 total

includes taxes & fees

Nov 22 - Nov 23

A swimming pool with a bridge structure, surrounded by buildings with outdoor seating and a clear sky.

19. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Ally Marie

NT$4,755 total

includes taxes & fees

Nov 22 - Nov 23

A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and a television screen.

20. Embassy Suites by Hilton Phoenix Scottsdale

17.8 km from Mayo Clinic Scottsdale

Matthew

NT$4,995 total

includes taxes & fees

Nov 22 - Nov 23

View all properties

Top Mayo Clinic Scottsdale Hotel Reviews

A living room with a sofa, a coffee table, and a kitchen area with a refrigerator and microwave.

Starlite Motel

Central Mesa

10/10 Excellent

Virginia

A group of people dining at an outdoor table with a view of a pool and palm trees.

Mountain Shadows Resort Scottsdale

Paradise Valley

10/10 Excellent

Rachael

Hyatt House North Scottsdale

Scottsdale

10/10 Excellent

Alicia

Home2 Suites by Hilton Mesa Longbow, AZ

Falcon Field Area

10/10 Excellent

Alvin

A modern lounge area with a sectional sofa, armchairs, and a coffee table.

The 233 Suites Unscripted by Hyatt

Downtown

10/10 Excellent

Jade

Comfort Suites Scottsdale Talking Stick Entertainment District

Scottsdale

10/10 Excellent

Darla

Canopy by Hilton Scottsdale Old Town

Old Town

10/10 Excellent

Shahar

Courtyard Scottsdale Salt River

Scottsdale

10/10 Excellent

Monica

An outdoor patio area with a central fire feature, seating arrangements, and a covered walkway.

Residence Inn Scottsdale Salt River

Scottsdale

10/10 Excellent

Maria Robelle

A modern lounge area with seating, a bar, and a fireplace.

Hotel Valley Ho

Old Town

10/10 Excellent

Andrew T

Inn at Eagle Mountain

Eagle Mountain

10/10 Excellent

carla

A pool area with multiple swimming pools, lounge chairs, and potted plants.

Fairfield Inn & Suites by Marriott Tempe

Tempe

10/10 Excellent

I planned a weekend staycation and just wanted a quiet weekend. The price was shockingly great for the location and quality, the reviews and photos sold me and it didn't disappoint. The pool is beautiful. The restaurant in the hotel is pretty good as well, we ordered the Cowboy Burger and the Surf n Turf Burger and both were very good. The hotel was clean, the location is convenient being by Tempe Marketplace so there's plenty to eat and do, and it was overall a great option. I'd absolutely stay...

Krimsun

A modern outdoor living area with a fire pit, comfortable seating, and a city view at dusk.

Sanctuary Camelback Mountain Resort and Spa

Camel Dale Properties

10/10 Excellent

Everything was wonderful. Our room was great, the staff at the pool were friendly. My only complaint is when we checked out and received our bill, there were several extra charges that we did not have and I Had to call several times to get them to correct our bill. We took things from the mini bar. For example, the wine was $35, and we were charged $45. They said there was a $7 tax fee and a $3 restock fee. We were also charged for a charger we never asked for. We took a beer and chips...

Anonymous traveler

A hotel pool area with sun loungers, a children's play area, and a building with a sign.

Home2 Suites by Hilton Scottsdale Salt River

Scottsdale

10/10 Excellent

Tracy

Wekopa Casino Resort

Fort McDowell

10/10 Excellent

Helen

Frequently Asked Questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,666

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. Talking Stick Resort

4. Hyatt Place Phoenix/Mesa

5. Close to Hiking! Family-friendly Mesa Retreat

6. Home2 Suites by Hilton Mesa Longbow, AZ

7. Comfort Suites Scottsdale Talking Stick Entertainment District

8. Spark by Hilton Fountain Hills Scottsdale

9. Springhill Suites Phoenix Scottsdale Marriott

10. Fountain Park Hotel, BW Signature Collection

11. Aiden by Best Western Scottsdale North

12. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

13. Hyatt House North Scottsdale

14. Hyatt Place Scottsdale - North

15. Wekopa Casino Resort

16. Home2 Suites by Hilton Scottsdale North

17. Courtyard by Marriott Scottsdale North

18. Courtyard Scottsdale Salt River

19. Holiday Inn & Suites Scottsdale North - Airpark by IHG

20. Embassy Suites by Hilton Phoenix Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Starlite Motel

10/10 Excellent

Frequently Asked Questions

What's the area like around Mayo Clinic Scottsdale?

What's the best place to stay near Mayo Clinic Scottsdale?

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

What can I see and do near Mayo Clinic Scottsdale?

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