Midtown 4 Stars Hotels
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Midtown 4 Star Hotels
Compare Midtown 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Renaissance St. Louis Airport Hotel
Renaissance St. Louis Airport Hotel
8.4 out of 10, Very Good, (1010)
The price is NT$3,588
NT$4,198 total
includes taxes & fees
Nov 1 - Nov 2

Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
8.6 out of 10, Excellent, (3982)
The price is NT$3,710
NT$4,375 total
includes taxes & fees
Nov 2 - Nov 3

21C Museum Hotel St Louis
21C Museum Hotel St Louis
9.0 out of 10, Wonderful, (1393)
The price is NT$4,899
NT$5,880 total
includes taxes & fees
Nov 2 - Nov 3

St. Louis Union Station Hotel, Curio Collection by Hilton
St. Louis Union Station Hotel, Curio Collection by Hilton
8.4 out of 10, Very Good, (1027)
The price is NT$5,247
NT$6,241 total
includes taxes & fees
Oct 9 - Oct 10

Marriott St. Louis Grand
Marriott St. Louis Grand
8.2 out of 10, Very Good, (1050)
The price is NT$4,105
NT$4,882 total
includes taxes & fees
Nov 1 - Nov 2

DoubleTree by Hilton St. Louis Airport
DoubleTree by Hilton St. Louis Airport
7.8 out of 10, Good, (824)
The price is NT$3,464
NT$4,064 total
includes taxes & fees
Oct 12 - Oct 13

River City Casino & Hotel
River City Casino & Hotel
9.0 out of 10, Wonderful, (1395)
The price is NT$2,676
NT$3,556 total
includes taxes & fees
Oct 26 - Oct 27

Live by Loews - St.Louis
Live by Loews - St.Louis
9.2 out of 10, Wonderful, (1049)
The price is NT$5,139
NT$6,112 total
includes taxes & fees
Oct 5 - Oct 6
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Midtown.

Four Seasons Hotel St Louis
999 North Second Street, St. Louis, MO
The price is NT$12,924 per night from Oct 25 to Oct 26
NT$12,924
NT$15,112 total
Oct 25 - Oct 26
includes taxes & fees
9.4/10 Exceptional! (1,000 reviews)
Still don't see what you're looking for?
See all properties in Midtown.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Midtown Hotel Reviews

Renaissance St. Louis Airport Hotel
10/10 Excellent
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Midtown Hotels by Star Rating
Stay near popular Midtown attractions
- Hotels near St. Louis University
- Hotels near Chaifetz Arena
- Hotels near Scott Joplin House State Historic Site
- Hotels near Museum of Contemporary Religious Art
- Hotels near Samuel Cupples House
- Hotels near Busch Stadium
- Hotels near St. Louis Union Station
- Hotels near Gateway Arch
- Hotels near Washington University in St. Louis
- Hotels near St. Louis Zoo
- Hotels near Enterprise Center
- Hotels near Dome at America’s Center
- Hotels near City Museum
- Hotels near Forest Park
- Hotels near Mississippi River
- Hotels near Hollywood Casino Amphitheatre
- Hotels near America's Center Convention Complex
- Hotels near Ameristar Casino St. Charles
- Hotels near Barnes Jewish Hospital
- Hotels near Fox Theater
Explore more hotels
- 21C Museum Hotel St Louis
- The Arch Convention Hotel
- Forest Park Hotel by MDR
- Marriott St. Louis Grand
- Hilton St. Louis at the Ballpark
- Moonrise Hotel
- Drury Inn & Suites St. Louis Union Station
- DoubleTree by Hilton St. Louis Forest Park
- River City Casino & Hotel
- La Quinta Inn & Suites by Wyndham St. Louis Westport
- Hollywood Casino & Hotel St. Louis
- Live by Loews - St.Louis
- AC Hotel St. Louis Clayton
- The Royal Sonesta Chase Park Plaza St. Louis
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Aloft St. Louis Cortex
- Ameristar Casino Resort and Spa
- The West End
- Motel 6 Hazelwood, MO
- DoubleTree by Hilton St. Louis Airport
More ways to book
Expedia's Latest Trends
Hotels
Flights
Packages