A large white building with a dome and a statue in front, surrounded by fountains and trees.

Find Business Hotels in St. Louis, MO

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on St. Louis Business Hotels

Tonight
Sep 5 - Sep 6
Tomorrow
Sep 6 - Sep 7
Next weekend
Sep 11 - Sep 13
In two weeks
Sep 18 - Sep 20

Our top choices for St. Louis business-friendly hotels

A rooftop terrace with wicker furniture, offering a city view.
A modern hotel lobby with a bar area, seating arrangements, and a large chandelier.
A spacious lobby with a blue sofa, a glass coffee table, and a chandelier.
A hotel room with a large window offering a view of the Gateway Arch and a modern building.

1. Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
Downtown St. Louis
United States
misty
NT$4,271
NT$4,994 total
includes taxes & fees
Oct 5 - Oct 6
Drury Plaza Hotel St. Louis at the Arch
A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.
A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.
A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.
A hotel room with a bed, a desk, a television, and a lamp.

2. Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
St. Ann
United States
Darren
NT$2,847
NT$3,352 total
includes taxes & fees
Sep 27 - Sep 28
Pear Tree Inn St. Louis Airport
A lobby with a sofa, two armchairs, a coffee table, and a staircase.
A modern hotel room with a large window, a flat-screen TV mounted on the wall, a round dining table with chairs, and a patterned rug.
A spacious lobby with a sectional sofa, a white armchair, and a glass coffee table. There is a dining area in the background with a chandelier.
A park with a pathway, trees, and a modern sculpture.

3. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
Downtown St. Louis
United States
TRACY
NT$4,547
NT$5,362 total
includes taxes & fees
Sep 6 - Sep 7
Hyatt Regency St. Louis at The Arch
The Clayton Plaza Hotel sign with a stone wall and plants in front.
A hotel room with two beds, a desk, a chair, and a television.
A large conference room with rows of tables and chairs, a podium, and a buffet table with plates and napkins.
A lobby with a chandelier, a round table with a floral arrangement, and a painting on the wall.

4. Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
Clayton
United States
Gail
NT$3,320
NT$3,876 total
includes taxes & fees
Oct 4 - Oct 5
Clayton Plaza Hotel & Extended Stay
An indoor pool area with a hot tub, seating, and a stone wall.
A conference room with a large table, six chairs, a flat-screen TV, and a patterned carpet.
A reception desk with a marble top, wooden paneling, and a sign indicating it's the Drury Inn.

5. Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station
Downtown West
United States
Kelvin
NT$4,271
NT$5,080 total
includes taxes & fees
Oct 5 - Oct 6
Drury Plaza Hotel St. Louis Union Station
A large hotel with a prominent tower and multiple parking areas.
A crowded indoor space with a chandelier, brick walls, and tables where people are seated and standing.
A spacious lobby with a patterned carpet, a reception desk, and a seating area with a sofa and chairs.
A lobby with a large screen displaying "Hollywood Casino" and "Wood Casino" signs, multiple chandeliers, and a polished floor.

6. Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
Riverport
United States
Glenda
NT$2,955
NT$4,387 total
includes taxes & fees
Oct 5 - Oct 6
Hollywood Casino & Hotel St. Louis
A hotel with a prominent tower, a fountain in the courtyard, and a well-maintained garden.
A spacious living area with a staircase, a large painting, and a chandelier.
A modern bathroom with a large mirror, white vanity, and a bathtub.
A formal dining table set for six with a vase of white flowers, candles, and a view of buildings through large windows.

7. The Wildwood Hotel

The Wildwood Hotel
Wildwood
United States
Hailey
NT$2,791
NT$3,251 total
includes taxes & fees
Sep 30 - Oct 1
The Wildwood Hotel
A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.
A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.
A hotel room with a desk, chair, TV, and a framed picture on the wall.
A hotel room with two beds, a desk, a chair, and a large window with curtains.

8. Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
St. Ann
United States
Margaret
NT$3,496
NT$4,116 total
includes taxes & fees
Sep 14 - Sep 15
Wingate by Wyndham St. Louis Airport
A modern living area with a sofa, armchairs, a coffee table, and a kitchen in the background.
A modern lobby with a reception desk, seating area, and a fireplace.
A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.
A modern living room with a sectional sofa, a round coffee table, and large windows offering a view of the city.

9. Best Western St. Louis Inn

Best Western St. Louis Inn
St. Louis
United States
Bryan
NT$2,262
NT$2,601 total
includes taxes & fees
Sep 13 - Sep 14
Best Western St. Louis Inn
A rooftop terrace with outdoor seating, string lights, and a city skyline view.
A multi-story hotel with a classic architectural style, featuring a prominent entrance and a large sign indicating it is a hotel.
A modern lounge area with a central cylindrical light fixture, white seating, and artwork on the walls.
A modern hotel room with a large window, a bathtub, and a unique eye-themed pillow.

10. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
United States
Jordan
NT$3,998
NT$4,715 total
includes taxes & fees
Oct 2 - Oct 3
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
View all properties

Top St. Louis Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

8/10 Good
"The hotel is located in a great area, and it’s especially convenient that they offer on-site parking"
Margarita 2-night trip
Posted 3 hours ago
Clayton Plaza Hotel & Extended Stay
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

10/10 Excellent
"Great location, great staff, and convenient"
David 2-night trip
Posted 16 hours ago
Hyatt Regency St. Louis at The Arch
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

8/10 Good
"Room was clean Pillows not comfy There was no cold water-odd as no hot water is the common problem with water but too hot to take a shower !!!"
Mary 1-night trip
Posted 18 hours ago
Ameristar Casino Resort and Spa
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent
"Nice place to stay. Great parking, easy in and out even in my pickup truck. Good breakfast. Nothing over the top but good customer service and nice clean rooms."
David 4-night trip
Posted 21 hours ago
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Frequently asked questions

How much do business-friendly hotels in St. Louis cost?
You can expect to pay between NT$2,601 and NT$5,362 per night for business-friendly hotels in St. Louis. Awesome deals on properties that are suitable for work-related guests are just a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in St. Louis?
A lot of corporate travelers recommend Drury Inn & Suites St. Louis Brentwood. This 3-stars property offers amenities such as a swimming pool and WiFi. Drury Plaza Hotel St. Louis at the Arch is another sought-after option. It has a 3-stars rating and conveniences including a swimming pool and a terrace. You'll have your pick of multiple business-friendly hotels in St. Louis that have a total average guest review rating of 9.0.
How many business-friendly hotels are there in St. Louis?
When your job takes you on the road in St. Louis, you'll have 195 business-friendly hotels to pick from. These stays offer a well-suited location with the conveniences corporate travelers need.
What are the best cheap business-friendly hotels in St. Louis?
Save money on your work trip to St. Louis by choosing one of our business-friendly hotels that start from only NT$2,601 per night. One inexpensive property is Hampton Inn & Suites St. Louis at Forest Park, which comes with amenities like a swimming pool and pillow top mattresses. Hampton Inn St. Louis-Downtown (At the Gateway Arch) is another leading pick for corporate travelers with a tight budget. It features pool sun loungers and an electric car charging station. However, your St. Louis visit shouldn't be all work and no play. Explore some fun and free attractions, such as Forest Park and Anheuser-Busch Brewery. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in St. Louis that are also business friendly?
Drury Plaza Hotel St. Louis at the Arch is popular with both business and leisure guests. Complimentary breakfast and WiFi are just a couple of the amenities available at this 3-stars St. Louis escape. Alternatively, vacation with the family and get down to work at Drury Inn & Suites St. Louis Forest Park. Enjoy the use of conveniences such as complimentary breakfast and housekeeping services at this top 3-stars option. St. Louis has tons of family-friendly attractions to check out when you're done with work. Take the kids on an outing to St. Louis Zoo and Forest Park.
Are there any 5-star business-friendly hotels in St. Louis?
St. Louis has some great 5-star options for corporate guests. Enjoy luxury perks after a busy day with clients at Four Seasons Hotel St Louis. Amenities at this business-friendly stay, around 2 kilometers from St. Louis's center, include a sauna and treatment rooms. Another high-end property that has everything you need for a work trip is The Ritz-Carlton, St. Louis. It features designer toiletries and concierge services and is 11 kilometers from the downtown area.
Why book your business-friendly hotel in St. Louis with Expedia?
With useful amenities like conference rooms, 24-hour front desk support and free parking, our business-friendly hotels come with all you'll need to settle that big contract — and then relax in the comfort of your room. Enter your preferred dates and travel destination and Expedia will help you plan the rest.
How can I find cheap business-friendly hotels in St. Louis?
Select the "business friendly" filter, listed just under the "traveler experience" heading, to find cheap business-friendly hotels in St. Louis. Then narrow your search by your budget and preferred hotel star rating. Looking for stays away from the center is another easy way to save.
What is there to do in St. Louis near my business-friendly hotel?
Whatever you love to do, St. Louis has a whole lot to keep you on the go. St. Louis Zoo, Forest Park and Fox Theater are on most visitors' sightseeing plans. Don't head home without exploring Anheuser-Busch Brewery, St. Louis Aquarium at Union Station and St. Louis Science Center either. With Expedia's business-friendly hotel deals, you can discover more renowned attractions like these with the cash you save.

Explore a world of travel with Expedia