Find Business Hotels in Central West End, MO

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Check availability on Central West End Business Hotels

Tonight
Dec 30 - Dec 31
Tomorrow
Dec 31 - Jan 1
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for Central West End business-friendly hotels

Lobby
AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End
4.0 star property
Central West End
9.0 out of 10, Wonderful, (686)
"Clean room, Helpful staff, Easy/cheap parking "
United States
Delaney
The price is NT$3,988
NT$4,703 total
includes taxes & fees
Jan 4 - 2026/1/5
AC Hotel St. Louis Central West End
In-room safe, desk, blackout drapes, iron/ironing board
DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End
8.2 out of 10, Very Good, (1000)
"Good breakfast and perfect location. "
United States
Chaquita
The price is NT$3,837
NT$4,525 total
includes taxes & fees
Jan 13 - 2026/1/14
DoubleTree by Hilton St. Louis Forest Park
Seasonal outdoor pool
The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.0 out of 10, Wonderful, (1003)
"Clean nice room, friendly staff, and good restaurants "
United States
Timothy
The price is NT$4,742
NT$6,518 total
includes taxes & fees
Jan 25 - 2026/1/26
The Royal Sonesta Chase Park Plaza St. Louis
Restaurant
Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG
3.5 star property
Central West End
8.2 out of 10, Very Good, (1000)
"Very friendly staff. Clean modern hotel room with comfortable bed and spacious shower! "
United States
Courtney
The price is NT$3,643
NT$4,640 total
includes taxes & fees
Jan 27 - 2026/1/28
Hotel Indigo St Louis - Central West End by IHG
Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.4 out of 10, Very Good, (4043)
"Staff was supper nice and it all went so smooth."
United States
Brayden
The price is NT$4,051
NT$4,777 total
includes taxes & fees
Jan 2 - 2026/1/3
Hyatt Regency St. Louis at The Arch
Lobby
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
St. Ann
9.4 out of 10, Exceptional, (2765)
"Very clean and will definitely stay there again next time!"
United States
Tonya
The price is NT$2,826
NT$3,327 total
includes taxes & fees
Jan 4 - 2026/1/5
Pear Tree Inn St. Louis Airport
Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1178)
"Great staff and location"
United States
Robin or David
The price is NT$3,046
NT$3,623 total
includes taxes & fees
Jan 25 - 2026/1/26
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Rooftop terrace
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (3289)
"The room was great , the staff was awesome breakfast and evening drinks and food were great overall it was an excellent stay "
United States
Daniel
The price is NT$4,522
NT$5,287 total
includes taxes & fees
Jan 4 - 2026/1/5
Drury Plaza Hotel St. Louis at the Arch
Terrace/patio
Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
Richmond Heights
9.4 out of 10, Exceptional, (842)
"Clean, would stay again."
United States
Eryka
The price is NT$3,177
NT$3,897 total
includes taxes & fees
Jan 4 - 2026/1/5
Courtyard by Marriott St. Louis Brentwood
Lobby
Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown
3.0 star property
Downtown West
8.0 out of 10, Very Good, (623)
"Great stay "
United States
Kevin
The price is NT$2,446
NT$2,861 total
includes taxes & fees
Jan 16 - 2026/1/17
Home2 Suites by Hilton St. Louis Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Central West End Hotel Reviews

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent
"It was nice clean and the front desk help were very professional. "
Peter 1-night trip
Posted 11 hours ago
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Frequently asked questions

Why book your business-friendly hotel in Central West End with Expedia?
We're here to help you find a fantastic business-friendly hotel when work takes you away from home. From conference spaces and meeting rooms to gyms and spas, our properties have the things you'll need to close that big deal.
How can I find cheap business-friendly hotels in Central West End?
When you're traveling for work in Central West End, our "business friendly" filter will help you find the right hotel. From free WiFi to concierge services and conference spaces, they come with the amenities you need for a productive and comfortable stay. You can also narrow your search by your preferred star rating and budget to view the cheapest options.

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