The illuminated Gateway Arch at night with a city skyline in the background.

Clayton 4 Stars Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Clayton 4 Star Hotels

Our top choices for Clayton 4-star hotels

A buffet with fruits, pastries, and beverages.

1. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very good, (1,169 reviews)
"Great stay"
United States
Anthony
The price is NT$3,772
NT$4,413 total
includes taxes & fees
Oct 29 - Oct 30
Renaissance St. Louis Airport Hotel
A lobby with a sofa, two armchairs, a coffee table, and a staircase.

2. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,346 reviews)
"Great stay"
United States
Johnny
The price is NT$4,281
NT$5,049 total
includes taxes & fees
Oct 30 - Oct 31
Hyatt Regency St. Louis at The Arch
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.

3. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (2,127 reviews)
"Great place to stay!"
United States
Zane
The price is NT$4,586
NT$5,522 total
includes taxes & fees
Nov 1 - Nov 2
21C Museum Hotel St Louis
A cozy lounge area with leather sofas, a fireplace, and a bar counter.

4. The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.8 out of 10, Excellent, (1,003 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
The price is NT$4,738
NT$5,626 total
includes taxes & fees
Oct 18 - Oct 19
The Cheshire
A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

5. Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,346 reviews)
"Great stay!"
United States
Molly
The price is NT$5,076
NT$6,037 total
includes taxes & fees
Oct 18 - Oct 19
Live by Loews - St.Louis
A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.

6. The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1,004 reviews)
"Amazing property, staff was very friendly, great location!!"
United States
Stacy
The price is NT$4,186
NT$4,895 total
includes taxes & fees
Oct 18 - Oct 19
The Westin St. Louis
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

7. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.2 out of 10, Wonderful, (1,004 reviews)
"The Sonesta is a lovely hotel with a beautiful pool. Our stay was a relaxing getaway and pleasant in every way."
United States
Kristina
The price is NT$5,140
NT$7,003 total
includes taxes & fees
Nov 1 - Nov 2
The Royal Sonesta Chase Park Plaza St. Louis
A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.

8. River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.2 out of 10, Wonderful, (1,810 reviews)
"Great accommodations - highly recommend"
United States
jodi
The price is NT$3,101
NT$4,106 total
includes taxes & fees
Oct 27 - Oct 28
River City Casino & Hotel
A rooftop terrace with outdoor seating, string lights, and a city skyline view.

9. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
Grand Center
8.8 out of 10, Excellent, (1,172 reviews)
"Always our top pick to stay when in town for travel. Great people, Great vibes and a Great distance from alot of downtown hot spots ☺️"
United States
Skylee
The price is NT$4,032
NT$4,754 total
includes taxes & fees
Oct 15 - Oct 16
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

10. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,075 reviews)
"Wonderful stay for a small bachelorette party. Had a wonderful time!"
United States
Kara
The price is NT$5,718
NT$7,213 total
includes taxes & fees
Oct 12 - Oct 13
Ameristar Casino Resort and Spa
A multi-story hotel with a prominent 'Marriott' sign, featuring a classic architectural style with a red brick facade and large windows.

11. Marriott St. Louis Grand

Marriott St. Louis Grand
4.0 star property
Downtown St. Louis
8.4 out of 10, Very good, (1,001 reviews)
"Great hotel"
United States
Andrew
The price is NT$4,853
NT$5,771 total
includes taxes & fees
Oct 20 - Oct 21
Marriott St. Louis Grand
A rooftop restaurant with round tables, chairs, and a view of the city.

12. Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (2,038 reviews)
"Great location"
United States
Katherine
The price is NT$5,146
NT$6,120 total
includes taxes & fees
Nov 3 - Nov 4
Moonrise Hotel
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

13. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
Brentwood
9.6 out of 10, Exceptional, (1,001 reviews)
"Excellent place to stay. Beautiful hotel, amazing friendly and attentive staff. Would highly recommend!!"
United States
Janell
The price is NT$4,182
NT$4,966 total
includes taxes & fees
Nov 1 - Nov 2
Drury Plaza Hotel St. Louis Brentwood
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

14. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
9.0 out of 10, Wonderful, (1,348 reviews)
"It was a pleasant stay, and the location was ideal."
United States
John
The price is NT$3,772
NT$4,486 total
includes taxes & fees
Oct 18 - Oct 19
Embassy Suites by Hilton St. Louis Downtown
A modern hotel with a prominent Hilton sign, surrounded by high-rise buildings and a clear sky.

15. Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis
7.6 out of 10, Good, (1,281 reviews)
"Staff was very friendly and helpful. Room was clean and rooftop bar was great!"
United States
kristen
The price is NT$4,686
NT$5,573 total
includes taxes & fees
Oct 18 - Oct 19
Hilton St. Louis at the Ballpark
A brick building with a tower, large windows, and a fountain in the garden.

16. Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
Frontenac
8.8 out of 10, Excellent, (1,003 reviews)
"Terrific location in the St. Louis area and very helpful staff with many amenities in the hotel."
United States
Linda L
The price is NT$4,424
NT$5,154 total
includes taxes & fees
Nov 1 - Nov 2
Hilton St. Louis Frontenac
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a modern building with large windows.

17. Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (787 reviews)
"Staff was outstanding. Location and room ideal."
United States
Steven
The price is NT$4,858
NT$5,719 total
includes taxes & fees
Oct 18 - Oct 19
Le Méridien St. Louis Clayton
A modern dining area with round tables, orange chairs, and a decorative wall with pottery.

18. Marriott St. Louis Airport

Marriott St. Louis Airport
4.0 star property
Edmundson
8.0 out of 10, Very good, (1,003 reviews)
"I love the Brand !!"
United States
Sha
The price is NT$4,553
NT$5,479 total
includes taxes & fees
Oct 30 - Oct 31
Marriott St. Louis Airport
A bar area with a central bar, multiple stools, and a chandelier.

19. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1,385 reviews)
"Great place"
United States
Carol
The price is NT$3,544
NT$4,215 total
includes taxes & fees
Oct 18 - Oct 19
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
A spacious lobby with high arched ceilings, ornate columns, and a central fountain.

20. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.8 out of 10, Excellent, (1,002 reviews)
"The property is beautiful, very well kept. The room was very clean. Staff was very helpful"
United States
Maryann
The price is NT$5,210
NT$6,196 total
includes taxes & fees
Oct 31 - Nov 1
St. Louis Union Station Hotel, Curio Collection by Hilton
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Clayton.
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO
The price is NT$11,972 per night from Oct 12 to Oct 13
NT$11,972
NT$13,999 total
Oct 12 - Oct 13
includes taxes & fees
Still don't see what you're looking for?
See all properties in Clayton.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Clayton Hotel Reviews

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

8/10 Good
"Room was smaller than I expected. Staffs were very kind and helpful."
kijoon 1-night trip
Posted 8 days ago
Le Méridien St. Louis Clayton

Frequently asked questions

What are the best 4-star hotels in Clayton?
Le Méridien St. Louis Clayton is a 4-star hotel in Clayton that ranks highly among Expedia guests. A swimming pool and a terrace are just a couple of its amenities. Travelers also recommend The Cheshire. From designer toiletries to a pillowtop mattress, it offers conveniences that cater to every aspect of your enjoyment and relaxation.
How much does it cost to stay in a 4-star hotel in Clayton?
With Expedia's search and sort filters, locking in a superb deal on a 4-star hotel in Clayton just got easier. Start by entering your chosen travel dates and length of your stay. Then sort the results by price and pick the option that best fits your style and budget.

  • Search for the lowest price from NT$13,999

What's the difference between 5-star and 4-star hotels in Clayton?
If you choose to vacation at a 4-star hotel in Clayton, you'll usually find loads of conveniences to ensure you're comfortable, such as a restaurant, pool and gym. You can look forward to high-quality service and upscale surroundings. Go for a 5-star hotel and you'll get a few extra bells and whistles — think on-site spas, 24-hour front desk and opulent turndown services. You're likely to get extra amenities and premium services at a 5-star retreat, but both are awesome options for luxury guests.

Explore a world of travel with Expedia