Find Resorts & Hotels with Spas in Odessa, MO

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Odessa Resorts & Hotels with Spas

Top Odessa Resorts & Hotels with Spas

Top Odessa Hotel Reviews

Drury Inn & Suites Kansas City Independence

Drury Inn & Suites Kansas City Independence

10/10 Excellent
"Great staff and they give you a nice buffet breakfast and dinner for free! "
Elaine 1-night trip
Posted 3 days ago
Drury Inn & Suites Kansas City Independence

Frequently asked questions

Looking for a spa hotel in Odessa?
Forget the stress of everyday life and book yourself a lush spa hotel. Hotels with spas are a great way to break away from your routine and add a layer of luxury to your weekend away.
What's there to see and do in Odessa?
Experience Odessa and visit Powell Gardens, Arcadian Moon Vineyards and Winery, and Lake Remembrance. If you have a bit of extra time while you're in the area, you might want to check out Blue Spring and Burr Oak Woods Conservation Area.
What is a Odessa spa hotel?
Spa hotels in Odessa provide lodging and have an on-site spa which offers services like couples massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.