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Our top choices for Florida Keys National Marine Sanctuary hotels

1. Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
3.5 star property
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
10.0 out of 10, Exceptional, (1,001 reviews)
"We really enjoyed our stay! The staff were amazing and the room was perfect!"
United States
Teresa
The price is NT$10,239
NT$11,519 total
includes taxes & fees
Nov 30 - Dec 1
Almond Tree Inn Hotel - Adults Only

2. Douglas House - Adults Only

Douglas House - Adults Only
3.0 star property
Uptown - Upper Duval, 0.9 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (574 reviews)
"Loved our stay! I would definitely stay there again."
United States
Maricela
The price is NT$5,904
NT$7,306 total
includes taxes & fees
Nov 3 - Nov 4
Douglas House - Adults Only

3. Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Uptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,000 reviews)
"Stayed there for a week for our honeymoon, could not have had a better stay."
United States
ben
The price is NT$10,244
NT$11,524 total
includes taxes & fees
Nov 3 - Nov 4
Orchid Key Inn - Adults Only

4. H2O Suites - Adults Only

H2O Suites - Adults Only
3.5 star property
Uptown - Upper Duval, 1.1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (671 reviews)
"Amazing stay! Loved the private pool!"
United States
Kimberly
The price is NT$11,703
NT$15,366 total
includes taxes & fees
Nov 30 - Dec 1
H2O Suites - Adults Only

5. Key West Villas

Key West Villas
3.5 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (279 reviews)
"Great location and very hospitable hotel owners"
United States
Margaret
The price is NT$7,305
NT$8,219 total
includes taxes & fees
Nov 3 - Nov 4
Key West Villas

6. The Gardens Hotel

The Gardens Hotel
4.0 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,002 reviews)
"Really nice place, We strongly recommend!"
United States
Gisele
The price is NT$8,765
NT$9,860 total
includes taxes & fees
Dec 1 - Dec 2
The Gardens Hotel

7. Alexander's Guesthouse - Adult Exclusive

Alexander's Guesthouse - Adult Exclusive
3.5 star property
Old Town Key West, 1.7 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (174 reviews)
"We had such a great stay, nice property, Great location , the staff was helpful, friendly and fantastic! Delicious breakfast included … we really loved this place and we are looking forward to come back!"
United States
Nestor
The price is NT$4,078
NT$5,844 total
includes taxes & fees
Nov 3 - Nov 4
Alexander's Guesthouse - Adult Exclusive

8. The Marquesa Hotel

The Marquesa Hotel
3.5 star property
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,001 reviews)
"This is my favorite hotel in the world, and Key West"
United States
Josh
The price is NT$13,272
NT$16,765 total
includes taxes & fees
Nov 29 - Nov 30
The Marquesa Hotel

9. The Conch House Heritage Inn

The Conch House Heritage Inn
3.5 star property
Old Town Key West, 1.1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (197 reviews)
"We really enjoyed getting to know the staff. The breakfast was excellent and everything was in walking distance."
United States
Jennifer
The price is NT$10,875
NT$12,234 total
includes taxes & fees
Nov 24 - Nov 25
The Conch House Heritage Inn

10. Duval House

Duval House
3.0 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,128 reviews)
"Great stay!"
United States
Dennis
The price is NT$6,161
NT$7,632 total
includes taxes & fees
Nov 11 - Nov 12
Duval House

11. Island City House Hotel

Island City House Hotel
3.0 star property
Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,003 reviews)
"Great place with lots of character and perfect location."
United States
Elise
The price is NT$7,717
NT$8,682 total
includes taxes & fees
Nov 3 - Nov 4
Island City House Hotel

12. Santa Maria Suites

Santa Maria Suites
4.0 star property
Uptown - Upper Duval, 1.3 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,001 reviews)
"Great place for families"
United States
Anthony
The price is NT$12,355
NT$16,099 total
includes taxes & fees
Dec 1 - Dec 2
Santa Maria Suites

13. The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West, 1.6 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,001 reviews)
"Fun apartment style living in Key West…fun little patio with coffee and continental breakfast. Make sure you look at the check in hours :) great spot makes you feel local"
United States
Justyn
The price is NT$5,164
NT$6,625 total
includes taxes & fees
Nov 3 - Nov 4
The Grand Guesthouse

14. The Mermaid & Alligator

The Mermaid & Alligator
3.5 star property
Old Town Key West, 1.2 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (331 reviews)
"such a lovely location. nice and quiet for a restful stay. staff was attentive to all our needs. would definitely return"
United States
christine
The price is NT$10,591
NT$11,915 total
includes taxes & fees
Nov 22 - Nov 23
The Mermaid & Alligator

15. Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
4.0 star property
Uptown - Upper Duval, 1.2 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,000 reviews)
"staff was super friendly and accomodating"
United States
Janet
The price is NT$6,366
NT$11,288 total
includes taxes & fees
Nov 8 - Nov 9
Southernmost House - Adult Exclusive

16. L'Habitation Guest House - Adults Only

L'Habitation Guest House - Adults Only
2.5 star property
Historic Seaport, 0.8 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,000 reviews)
"Everything was amazing. Drew runs a beautiful place."
United States
Matthew
The price is NT$5,399
NT$6,074 total
includes taxes & fees
Nov 29 - Nov 30
L'Habitation Guest House - Adults Only

17. Westwinds Inn

Westwinds Inn
3.5 star property
Historic Seaport, 1.4 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,003 reviews)
"Breakfast was great . Pools were great and easy walk or bike ride to Duval street"
United States
Shari
The price is NT$6,454
NT$7,261 total
includes taxes & fees
Nov 3 - Nov 4
Westwinds Inn

18. Coco Plum Inn

Coco Plum Inn
3.0 star property
Downtown Key West, 0.6 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (575 reviews)
"Location was perfect"
United States
August
The price is NT$8,330
NT$9,372 total
includes taxes & fees
Nov 3 - Nov 4
Coco Plum Inn

19. Silver Palms Inn & Historic Homes

Silver Palms Inn & Historic Homes
3.5 star property
Old Town Key West, 1.3 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,029 reviews)
"Great location Beautiful property very clean and quiet. Great omelet station w breakfast."
United States
Carleen
The price is NT$4,958
NT$7,779 total
includes taxes & fees
Dec 2 - Dec 3
Silver Palms Inn & Historic Homes

20. Ambrosia Key West

Ambrosia Key West
3.5 star property
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,004 reviews)
"Great location beautiful property we enjoyed our stay !"
United States
daniela
The price is NT$7,711
NT$8,675 total
includes taxes & fees
Nov 3 - Nov 4
Ambrosia Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Florida Keys National Marine Sanctuary

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A modern hotel room with a large bed, a nightstand, a bedside table, and a bathroom visible through an open door.
Almond Tree Inn Hotel - Adults Only
3.5 star property
10.0
Exceptional
1,001 reviews
View
A tropical outdoor area with palm trees, hanging plants, and string lights.
Douglas House - Adults Only
3.0 star property
9.8
Exceptional
574 reviews
View
A pool area with lounge chairs and a table, surrounded by palm trees.
Orchid Key Inn - Adults Only
3.5 star property
9.8
Exceptional
1,000 reviews
View
A modern outdoor area with a pool, lounge chairs, and a bar area.
H2O Suites - Adults Only
3.5 star property
9.8
Exceptional
671 reviews
View
A gated entrance to Villas Key West with a brick pathway leading to the gate.
Key West Villas
3.5 star property
9.8
Exceptional
279 reviews
View

Top Florida Keys National Marine Sanctuary Hotel Reviews

Other attractions near Florida Keys National Marine Sanctuary

Frequently asked questions

What's the area like around Florida Keys National Marine Sanctuary?
Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, biking, and lively festivals. If you're looking for a convenient place to stay, check out the 1487 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Florida Keys National Marine Sanctuary?
Adjacent to Florida Keys National Marine Sanctuary, Tranquility Guest House is one of the top choices for your stay based on our traveler data, and this hotel offers an outdoor pool and free WiFi. Other good choices close by include Southernmost Beach Resort and Guesthouses and La Concha Key West, Autograph Collection.
How many hotels will I be able to find near Florida Keys National Marine Sanctuary?
Expedia has 1487 hotels and other accommodations within a mile from Florida Keys National Marine Sanctuary.
If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?
Yes, most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best options available near Florida Keys National Marine Sanctuary.
Where can I learn more about changing or cancelling my trip in the area near Florida Keys National Marine Sanctuary?
To find more details about updating your stay near Florida Keys National Marine Sanctuary or cancelling it, head over to our customer service page.
What can I see and do near Florida Keys National Marine Sanctuary?
Florida Keys Eco - Discovery Center, Harry S. Truman Little White House, and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum, and Fort East Martello Museum and Gallery are some of the notable landmarks to see in the area. You can watch performances at Red Barn Theater, Coffee Butler Amphitheater, and Key West Film Society if you're interested in local theater.

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