Default HTG hotel image

Find hotels near Florida Keys National Marine Sanctuary, Key West from NT$4,126

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Sep 8 - Sep 9
Tomorrow
Sep 9 - Sep 10
This weekend
Sep 11 - Sep 13
Next weekend
Sep 18 - Sep 20

Filter by

Star rating

Guest rating

Our top choices for Florida Keys National Marine Sanctuary hotels

1. Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
Uptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary
United States
Nicholas
NT$5,087
NT$5,723 total
includes taxes & fees
Sep 14 - Sep 15
Orchid Key Inn - Adults Only

2. Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages
Historic Seaport, 1 km from Florida Keys National Marine Sanctuary
United States
Robin
NT$5,332
NT$5,998 total
includes taxes & fees
Sep 10 - Sep 11
Simonton Court Historic Inn & Cottages

3. The Gardens Hotel

The Gardens Hotel
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
United States
Jason
NT$5,310
NT$5,973 total
includes taxes & fees
Sep 21 - Sep 22
The Gardens Hotel

4. The Porch on Frances Inn

The Porch on Frances Inn
Old Town Key West, 1.6 km from Florida Keys National Marine Sanctuary
United States
Corrynne
NT$3,660
NT$5,064 total
includes taxes & fees
Sep 15 - Sep 16
The Porch on Frances Inn

5. The Marquesa Hotel

The Marquesa Hotel
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
United States
LISA
NT$6,961
NT$9,605 total
includes taxes & fees
Sep 27 - Sep 28
The Marquesa Hotel

6. Douglas House - Adults Only

Douglas House - Adults Only
Uptown - Upper Duval, 0.9 km from Florida Keys National Marine Sanctuary
United States
michael
NT$3,718
NT$4,601 total
includes taxes & fees
Sep 29 - Sep 30
Douglas House - Adults Only

7. H2O Suites - Adults Only

H2O Suites - Adults Only
Uptown - Upper Duval, 1.1 km from Florida Keys National Marine Sanctuary
United States
Kourosh
NT$8,802
NT$12,032 total
includes taxes & fees
Sep 9 - Sep 10
H2O Suites - Adults Only

8. Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
Old Town Key West, 1.7 km from Florida Keys National Marine Sanctuary
United States
Jaime
NT$3,095
NT$4,673 total
includes taxes & fees
Sep 9 - Sep 10
Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

9. The Conch House Heritage Inn

The Conch House Heritage Inn
Old Town Key West, 1.1 km from Florida Keys National Marine Sanctuary
United States
John
NT$5,619
NT$6,322 total
includes taxes & fees
Sep 13 - Sep 14
The Conch House Heritage Inn

10. Island City House Hotel

Island City House Hotel
Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary
United States
Paul
NT$4,851
NT$5,457 total
includes taxes & fees
Sep 9 - Sep 10
Island City House Hotel

11. Duval House

Duval House
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
United States
Robert
NT$3,132
NT$4,204 total
includes taxes & fees
Sep 16 - Sep 17
Duval House

12. Tropical Inn

Tropical Inn
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
United States
Anthony
NT$3,044
NT$4,213 total
includes taxes & fees
Sep 9 - Sep 10
Tropical Inn

13. The Grand Guesthouse

The Grand Guesthouse
Old Town Key West, 1.6 km from Florida Keys National Marine Sanctuary
United States
Alissa
NT$3,559
NT$4,793 total
includes taxes & fees
Sep 9 - Sep 10
The Grand Guesthouse

14. The Mermaid & Alligator

The Mermaid & Alligator
Old Town Key West, 1.2 km from Florida Keys National Marine Sanctuary
United States
Johnny
NT$5,679
NT$6,389 total
includes taxes & fees
Sep 14 - Sep 15
The Mermaid & Alligator

15. Santa Maria Suites

Santa Maria Suites
Uptown - Upper Duval, 1.3 km from Florida Keys National Marine Sanctuary
United States
June Young
NT$8,802
NT$12,032 total
includes taxes & fees
Sep 15 - Sep 16
Santa Maria Suites

16. Silver Palms Inn & Historic Homes

Silver Palms Inn & Historic Homes
Old Town Key West, 1.3 km from Florida Keys National Marine Sanctuary
United States
Shawn
NT$2,527
NT$4,973 total
includes taxes & fees
Sep 10 - Sep 11
Silver Palms Inn & Historic Homes

17. Westwinds Inn

Westwinds Inn
Historic Seaport, 1.4 km from Florida Keys National Marine Sanctuary
United States
Tricia
NT$3,668
NT$4,126 total
includes taxes & fees
Sep 13 - Sep 14
Westwinds Inn

18. Coco Plum Inn

Coco Plum Inn
Downtown Key West, 0.6 km from Florida Keys National Marine Sanctuary
United States
Jake
NT$4,235
NT$4,765 total
includes taxes & fees
Sep 9 - Sep 10
Coco Plum Inn

19. Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
Uptown - Upper Duval, 1.2 km from Florida Keys National Marine Sanctuary
United States
Mark
NT$4,395
NT$8,937 total
includes taxes & fees
Oct 1 - Oct 2
Southernmost House - Adult Exclusive

20. Weatherstation Inn

Weatherstation Inn
Truman Annex, 0.6 km from Florida Keys National Marine Sanctuary
United States
Svetlana
NT$5,347
NT$6,016 total
includes taxes & fees
Sep 16 - Sep 17
Weatherstation Inn
View all properties

Compare popular hotels close to Florida Keys National Marine Sanctuary

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Property grounds
Orchid Key Inn - Adults Only
9.8
Exceptional
1,010 reviews
View
Queen with Pool View
Simonton Court Historic Inn & Cottages
9.8
Exceptional
1,005 reviews
View
Exterior detail
The Gardens Hotel
9.8
Exceptional
1,004 reviews
View
Front of property
The Porch on Frances Inn
9.8
Exceptional
139 reviews
View
Exterior
The Marquesa Hotel
9.8
Exceptional
1,002 reviews
View

Top Florida Keys National Marine Sanctuary Hotel Reviews

Douglas House - Adults Only

Douglas House - Adults Only

10/10 Excellent
"Great spot right off Duval. Pool was nice with coffee, tea, and juices available 24x7. Jen at the front desk was awesome, Hanzi was there the last day and was also helpful. Only thing that was a little annoying was the keypads. By the end of the weekend, we had it down 😁"
Cheryl 3-night trip
Posted 8 hours ago
Douglas House - Adults Only
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

10/10 Excellent
"Everyone was amazing, and the room was super clean! Comfy cozy and location was great!"
Sabrina Victoria 5-night trip
Posted 9 hours ago
Southernmost Beach Resort and Guesthouses
Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa

10/10 Excellent
"Loved the stay. Definitely will be back"
Kelli 4-night trip
Posted 11 hours ago
Hyatt Centric Key West Resort and Spa
Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West

10/10 Excellent
"Best Hotel"
Clara 2-night trip
Posted 13 hours ago
Opal Key Resort & Marina, Key West
Pier House Resort & Spa

Pier House Resort & Spa

8/10 Good
"We loved this place and would stay here again. The staff were amazing. The rooms were clean. The shower was fantastic! The private beach was a plus. I only knocked off one star because there’s not really a good place to get coffee in the morning at the resort and the coffee fixings in the room were meager."
Sarah 3-night trip
Posted 13 hours ago
Pier House Resort & Spa
Winslow's Bungalows - Key West Historic Inns

Winslow's Bungalows - Key West Historic Inns

8/10 Good
"The exterior of the property is very beautiful, staff were all so kind and friendly, and the breakfast was a great perk every morning. Large property with 3 different parking lots and bike rentals. Very pet friendly resort, which was great since we were traveling with our senior dog."
Olga 3-night trip
Posted 14 hours ago
Winslow's Bungalows - Key West Historic Inns
Tranquility Guest House

Tranquility Guest House

8/10 Good
"The room was clean and the location was perfect."
Sandra 3-night trip
Posted 14 hours ago
Tranquility Guest House
Weatherstation Inn

Weatherstation Inn

10/10 Excellent
"Awesome spot"
Christian 1-night trip
Posted 1 day ago
Weatherstation Inn
Wicker Guesthouse

Wicker Guesthouse

8/10 Good
"Cute little place. Perfect location. Parking is kind of a hassle, but we walked everywhere. We did have a major issue with ants, tiny ones. Didn’t get much assistance to get that rectified. Other than that, good choice."
Michael 3-night trip
Posted 3 days ago
Wicker Guesthouse

Other attractions near Florida Keys National Marine Sanctuary

A yellow exhibit labeled 'NOAA's AQUARIUS UNDERSEA LAB' with a circular window and a door.

Florida Keys Eco - Discovery Center

8.8/10 (128 reviews)
Learn about the area’s important marine ecology at this comprehensive attraction that addresses global environmental concerns, interesting for visitors of all ages.
See properties
A brick corridor with arched ceilings and benches.

Fort Zachary Taylor Historic State Park

9.0/10 (4,544 reviews)
The displays of old weapons and interpretive panels in a fort at the heart of the southernmost state park in the continental U.S. provide information about the Civil War.
See properties
A wooden signpost with directional arrows pointing to various cities and their distances.
Photo by Martin Pettersson

Truman Beach

Why not spend a lazy afternoon at Truman Beach during your trip to Key West? Stroll along the seaside or discover the area's beautiful sunsets.
See properties
The Monroe County Courthouse with a clock tower, surrounded by trees and a clear blue sky.

Jackson Square

8.8/10 (110 reviews)
You can learn about the history of Key West with a stop at Jackson Square. Stroll along the seaside or discover the area's beautiful sunsets.
See properties

Coffee Butler Amphitheater

You can enjoy a show at Coffee Butler Amphitheater during your trip to Key West. Discover the area's lively bars and its entertainment choices.
See properties

USCGC Ingham Maritime Museum

You can spend an afternoon exploring the galleries in USCGC Ingham Maritime Museum during your trip to Key West.
See properties

Truman Waterfront Park

You can take time to visit Truman Waterfront Park during your travels to Key West. Discover the area's lively bars and its entertainment choices.
See properties

We Cycle Key West

You can search for that perfect souvenir at We Cycle Key West during your trip to Key West.
See properties

Frequently asked questions

What's the area like around Florida Keys National Marine Sanctuary?
Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, biking, and lively festivals. If you're looking for a convenient place to stay, check out the 1494 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Florida Keys National Marine Sanctuary?
Adjacent to Florida Keys National Marine Sanctuary, Tranquility Guest House is one of the top choices for your stay based on our traveler data, and this hotel offers an outdoor pool and free WiFi. Other good choices close by include Southernmost Beach Resort and Guesthouses and La Concha Key West, Autograph Collection.
How many hotels will I be able to find near Florida Keys National Marine Sanctuary?
Expedia has 1494 hotels and other accommodations within a mile from Florida Keys National Marine Sanctuary.
If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?
Yes, most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best options available near Florida Keys National Marine Sanctuary.
Where can I learn more about changing or cancelling my trip in the area near Florida Keys National Marine Sanctuary?
To find more details about updating your stay near Florida Keys National Marine Sanctuary or cancelling it, head over to our customer service page.
What can I see and do near Florida Keys National Marine Sanctuary?
Florida Keys Eco - Discovery Center, Harry S. Truman Little White House, and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum, and Fort East Martello Museum and Gallery are some of the notable landmarks to see in the area. You can watch performances at Waterfront Playhouse, Coffee Butler Amphitheater, and Key West Film Society if you're interested in local theater.

Explore a world of travel with Expedia