Find Family Hotels in Clayton, MO

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Our top choices for Clayton family-friendly hotels

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
Clayton
8.8 out of 10, Excellent, (3044)
"Clean room, good breakfast and good location "
United States
Martin
The price is NT$3,096
NT$3,614 total
includes taxes & fees
Dec 30 - Dec 31
Clayton Plaza Hotel & Extended Stay

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (681)
"The gym was amazing! "
United States
Hannah
The price is NT$3,747
NT$4,412 total
includes taxes & fees
Jan 1 - 2026/1/2
Le Méridien St. Louis Clayton

AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton
3.0 star property
Clayton
9.0 out of 10, Wonderful, (227)
"The room was very clean and well designed.very quiet and restful. We were even given adjoining rooms without asking "
United States
Elizabeth
The price is NT$4,086
NT$4,770 total
includes taxes & fees
Jan 4 - 2026/1/5
AC Hotel St. Louis Clayton

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
Clayton
8.4 out of 10, Very Good, (577)
"Love this place."
United States
Robert
The price is NT$4,118
NT$5,106 total
includes taxes & fees
Jan 1 - 2026/1/2
Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1168)
"Staff was helpful at suggesting places to eat and shop"
United States
Ann Marie
The price is NT$3,049
NT$3,626 total
includes taxes & fees
Jan 25 - 2026/1/26
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1254)
"Very cool hotel, rooms were clean and nice design, the food at the bar/restaurant was fantastic!!!"
United States
Cullin
The price is NT$3,454
NT$4,108 total
includes taxes & fees
Jan 3 - 2026/1/4
Embassy Suites by Hilton St. Louis Downtown

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1191)
"The staff was probably the best part of the stay. "
United States
Ja Nelle
The price is NT$3,067
NT$3,587 total
includes taxes & fees
Jan 3 - 2026/1/4
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Pear Tree Inn St. Louis Convention Center

Pear Tree Inn St. Louis Convention Center
3.0 star property
Downtown St. Louis
9.0 out of 10, Wonderful, (1056)
"It was perfect for our stay in St. Louis to visit the arch."
United States
Jacob
The price is NT$2,954
NT$3,455 total
includes taxes & fees
Jan 1 - 2026/1/2
Pear Tree Inn St. Louis Convention Center

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (3281)
"The room was great , the staff was awesome breakfast and evening drinks and food were great overall it was an excellent stay "
United States
Daniel
The price is NT$4,526
NT$5,292 total
includes taxes & fees
Jan 1 - 2026/1/2
Drury Plaza Hotel St. Louis at the Arch

The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1003)
"Great location "
United States
Gregory
The price is NT$3,981
NT$4,655 total
includes taxes & fees
Jan 3 - 2026/1/4
The Westin St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Clayton Hotel Reviews

Frequently asked questions

What's Clayton like for family-friendly vacations?
The welcoming destination of Clayton is a good choice if you've been thinking about a trip with your kids. The museums, soccer matches, and cafes are just some of the things that make this an attractive family vacation spot. Fly into St. Louis Lambert Intl. Airport (STL), which is the closest airport, or St. Louis, MO (SUS-Spirit of St. Louis), which is located 17.4 mi (28 km) from the center of Clayton.
What's the best accommodation for a family vacation to Clayton?
Le Méridien St. Louis Clayton is a hotel with an outdoor pool and a restaurant, and it's a top choice on Expedia for families. Other choices to stay with the kids include Seven Gables, St. Louis West, a Tribute Portfolio Hotel and AC Hotel St. Louis Clayton.
What's there to see and do with your family in Clayton?
While you are visiting Clayton, you might want to round up the kiddos and make time to see interesting attractions such as Shaw Park Tennis Center and Busch Stadium. Make sure you have lots of time for activities like Saint Louis Galleria Mall and St. Louis Zoo.

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