Find Family Hotels in Clayton, MO
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Clayton Family Hotels
Our top choices for Clayton family-friendly hotels
8.8 out of 10, Excellent, (3044)
"Clean room, good breakfast and good location "
Martin
The price is NT$3,096
NT$3,614 total
includes taxes & fees
Dec 30 - Dec 31
8.8 out of 10, Excellent, (681)
"The gym was amazing! "
Hannah
The price is NT$3,747
NT$4,412 total
includes taxes & fees
Jan 1 - 2026/1/2
9.0 out of 10, Wonderful, (227)
"The room was very clean and well designed.very quiet and restful. We were even given adjoining rooms without asking "
Elizabeth
The price is NT$4,086
NT$4,770 total
includes taxes & fees
Jan 4 - 2026/1/5
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Seven Gables, St. Louis West, a Tribute Portfolio HotelClayton
8.4 out of 10, Very Good, (577)
"Love this place."
Robert
The price is NT$4,118
NT$5,106 total
includes taxes & fees
Jan 1 - 2026/1/2
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Magnolia Hotel St. Louis, a Tribute Portfolio HotelDowntown St. Louis
8.8 out of 10, Excellent, (1168)
"Staff was helpful at suggesting places to eat and shop"
Ann Marie
The price is NT$3,049
NT$3,626 total
includes taxes & fees
Jan 25 - 2026/1/26
Embassy Suites by Hilton St. Louis Downtown
Embassy Suites by Hilton St. Louis DowntownDowntown St. Louis
8.8 out of 10, Excellent, (1254)
"Very cool hotel, rooms were clean and nice design, the food at the bar/restaurant was fantastic!!!"
Cullin
The price is NT$3,454
NT$4,108 total
includes taxes & fees
Jan 3 - 2026/1/4
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Hampton Inn St. Louis-Downtown (At the Gateway Arch)Downtown St. Louis
8.8 out of 10, Excellent, (1191)
"The staff was probably the best part of the stay. "
Ja Nelle
The price is NT$3,067
NT$3,587 total
includes taxes & fees
Jan 3 - 2026/1/4
Pear Tree Inn St. Louis Convention Center
Pear Tree Inn St. Louis Convention CenterDowntown St. Louis
9.0 out of 10, Wonderful, (1056)
"It was perfect for our stay in St. Louis to visit the arch."
Jacob
The price is NT$2,954
NT$3,455 total
includes taxes & fees
Jan 1 - 2026/1/2
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Clayton Hotel Reviews
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
- 5 Star Hotels in Clayton
- Adventure Hotels in University City
- Apartments in St Louis City County
- Winery Hotels in St. Louis
- Hotels near Mildred Lane Kemper Art Museum
- St. Louis Hotels
- Red Roof Inn Hotels in St. Louis
- Hotels near St. Louis Zoo
- Hotels with Bars in Central West End
- Hotels near Grant's Farm
- Hotels near Washington University in St. Louis
- Hotels near Barnes Jewish Hospital
- B&B in Olivette
- Hotels with Hot Tubs in Clayton
- Hotels with an Indoor Pool in Woodson Terrace
- Hotels near City Museum
- Resorts & Hotels with Spas in Frontenac
- Hotel Wedding Venues Hotels in Clayton
- Romantic Hotels in Clayton
- Hotels with a Pool in The Hill
- Boutique Hotels in Clayton
- Cheap Hotels in Downtown St. Louis
- Hotels near Saint Louis Galleria Mall
- Hotels with a Pool in Maryland Heights
- Romantic Hotels in Edmundson
- Resorts & Hotels with Spas in Central West End
- Adults Only Resorts & in St. Louis
- Resorts & Hotels with Spas in St. Louis
- Hotels near St. Alphonsus Liguori Catholic Church
- Webster Groves Hotels
- 5 Star Hotels in Richmond Heights
- 5 Star Hotels in Kirkwood
- Hotels near St. Louis Science Center
- Hotels near Central West End Station
- Shopping Hotels in Near North Riverfront
- B&B in Webster Groves
- Hotels near St. Louis University
- Business Hotels in Creve Coeur
- 5 Star Hotels in Ladue
- Frontenac Hotels
- Hotels with an Indoor Pool in St. Louis
- Guest Houses in Sunnen Station
- Hotels near Chaifetz Arena
- Romantic Hotels in Richmond Heights
- Hotels near The Muny Theater
- Brentwood Hotels
- Hotels with an Indoor Pool in Frontenac
- Green Hotels in Breckenridge Hills
- Houseboats in St Louis City County
- Hotel Wedding Venues Hotels in St. Louis
- Historic Hotels in Central West End
- Luxury Hotels in Frontenac
- Business Hotels in Brentwood
- Drury Inn & Suites Hotels in St. John
- Hotels near America's Center Convention Complex
- Business Hotels in Clayton
- Hotels with a Pool in Richmond Heights
- Hotels with an Indoor Pool in Central West End
- Business Hotels in St. Louis
- Flights to Richmond Heights
- Flights from Louisville (SDF) to St. Louis (STL)
- Flights from Homer (HOM) to St. Louis (STL)
- Flights to Rock Hill
- Flights from Fayetteville (FAY) to St. Louis (STL)
- Flights from Bismarck (BIS) to St. Louis (STL)
- Flights from Baltimore (BWI) to St. Louis (STL)
- Flights to Overland
- Flights from Champaign (CMI) to St. Louis (STL)
- Flights from Taipei (TPE) to St. Louis (STL)
- Flights from Washington (DCA) to St. Louis (STL)
- Flights from Sao Joao del Rei (JDR) to St. Louis (STL)
- Flights from Bodo (BOO) to St. Louis (STL)
- Visit Compton Heights
- Missouri History Museum
- St. Louis Zoo
- Barnes Jewish Hospital
- Pulitzer Foundation for the Arts
- Visit University City
- Forest Park
- St. Louis Science Center
- Overland Vacations
- Bruno David Gallery
- Chaifetz Arena
- Visit Creve Coeur
- The Muny Theater
- Visit Central West End
- Visit Olivette
- Visit Lindenwood Park
- Saint Louis Galleria Mall
- Cathedral Basilica of St. Louis
- St. Louis Art Museum