Find hotels in Serra Mesa, San Diego from NT$2,828

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Sep 17 - Sep 18
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Sep 19 - Sep 21
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Sep 26 - Sep 28

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Discover 9,006 Serra Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Serra Mesa hotels

Wyndham San Diego Bayside
Terrace/patio

Wyndham San Diego Bayside

4.0 star property
8.4 out of 10, Very Good, (5943)
"Great place to stay!!!!"
The price is NT$4,575
NT$6,056 total
includes taxes & fees
Oct 1 - Oct 2
Wyndham San Diego Bayside
Palihotel San Diego Gaslamp Quarter
Rooftop terrace

Palihotel San Diego Gaslamp Quarter

4.0 star property
8.8 out of 10, Excellent, (1791)
"Awesome place!!! "
The price is NT$3,112
NT$3,608 total
includes taxes & fees
Oct 13 - Oct 14
Palihotel San Diego Gaslamp Quarter
Hard Rock Hotel San Diego
Outdoor pool

Hard Rock Hotel San Diego

4.0 star property
9.0 out of 10, Wonderful, (2922)
"The stay was great! Highly recommend!!"
The price is NT$5,962
NT$8,302 total
includes taxes & fees
Sep 21 - Sep 22
Hard Rock Hotel San Diego
Loews Coronado Bay Resort
Exterior

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1034)
"Loved this stay, will be back! "
The price is NT$7,109
NT$9,281 total
includes taxes & fees
Sep 24 - Sep 25
Loews Coronado Bay Resort
Best Western Plus Marina Gateway Hotel
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3294)
"Good place to stay"
The price is NT$4,057
NT$4,470 total
includes taxes & fees
Sep 28 - Sep 29
Best Western Plus Marina Gateway Hotel
The Horton Grand, Downtown/Gaslamp Quarter
Serves dinner and happy hour

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
9.0 out of 10, Wonderful, (2544)
"Beautiful Boutique Hotel"
The Horton Grand, Downtown/Gaslamp Quarter
Gaslamp Plaza Suites
Lobby

Gaslamp Plaza Suites

3.5 star property
8.8 out of 10, Excellent, (1012)
"Great stay and great for tourist "
The price is NT$3,297
NT$3,751 total
includes taxes & fees
Sep 29 - Sep 30
Gaslamp Plaza Suites
The Sofia Hotel
Front of property

The Sofia Hotel

3.5 star property
8.4 out of 10, Very Good, (1572)
"I was very happy with my stay."
The Sofia Hotel
Sentral Gaslamp Quarter
Premium bedding, pillowtop beds, desk, laptop workspace

Sentral Gaslamp Quarter

3.0 star property
9.2 out of 10, Wonderful, (385)
"Great place to stay!"
The price is NT$5,386
NT$7,116 total
includes taxes & fees
Sep 21 - Sep 22
Sentral Gaslamp Quarter
The Bristol Hotel San Diego
Property entrance

The Bristol Hotel San Diego

3.5 star property
8.4 out of 10, Very Good, (1379)
"Great stay"
The Bristol Hotel San Diego
El Cordova Hotel on Coronado Island
Lobby

El Cordova Hotel on Coronado Island

3.5 star property
8.8 out of 10, Excellent, (1004)
"Perfect location! Close to beach, harbor and lots of dining options. Staff is very friendly and helpful. We stayed in the large suite which exceeded our expectations in every way."
El Cordova Hotel on Coronado Island
Legacy Resort Hotel & Spa
Garden

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2857)
"Amazing place to stay. "
The price is NT$5,274
NT$6,062 total
includes taxes & fees
Sep 26 - Sep 27
Legacy Resort Hotel & Spa
Days Inn by Wyndham San Diego Hotel Circle
Outdoor pool, a heated pool

Days Inn by Wyndham San Diego Hotel Circle

3.0 star property
8.0 out of 10, Very Good, (2336)
"We enjoyed our stay "
The price is NT$2,950
NT$3,391 total
includes taxes & fees
Sep 21 - Sep 22
Days Inn by Wyndham San Diego Hotel Circle
La Pensione Hotel
Exterior

La Pensione Hotel

3.0 star property
8.6 out of 10, Excellent, (1864)
"Friendly staff, lot of food options nearby"
La Pensione Hotel
The Dana on Mission Bay
2 outdoor pools, a heated pool, sun loungers

The Dana on Mission Bay

3.5 star property
8.8 out of 10, Excellent, (3745)
"Perfect stay!! "
The price is NT$4,575
NT$5,860 total
includes taxes & fees
Sep 28 - Sep 29
The Dana on Mission Bay
Glorietta Bay Inn Coronado Island
Front of property - evening/night

Glorietta Bay Inn Coronado Island

3.5 star property
8.6 out of 10, Excellent, (1005)
"Great location"
The price is NT$6,620
NT$8,699 total
includes taxes & fees
Sep 21 - Sep 22
Glorietta Bay Inn Coronado Island
Staypineapple, Hotel Z, Gaslamp San Diego
Premium bedding, pillowtop beds, desk, blackout drapes

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
9.4 out of 10, Exceptional, (1008)
"Very cute and comfortable stay"
The price is NT$4,207
NT$5,747 total
includes taxes & fees
Oct 1 - Oct 2
Staypineapple, Hotel Z, Gaslamp San Diego
Urban Boutique Hotel
Check-in/check-out kiosk

Urban Boutique Hotel

3.0 star property
8.6 out of 10, Excellent, (1254)
"Great hotel and excellent location!"
Urban Boutique Hotel
Bay Club Hotel & Marina
Exterior

Bay Club Hotel & Marina

3.5 star property
9.0 out of 10, Wonderful, (2943)
"We really enjoyed our stay"
The price is NT$4,682
NT$5,382 total
includes taxes & fees
Sep 21 - Sep 22
Bay Club Hotel & Marina
Hotel Palmeras Chula Vista
Front of property

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1868)
"Quiet area all around nice place to stay !!!"
The price is NT$1,927
NT$2,120 total
includes taxes & fees
Sep 18 - Sep 19
Hotel Palmeras Chula Vista
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Serra Mesa

Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most.
US Grant Hotel

Downtown San Diego

2 out of top 10 points of interest in this area

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Gaslamp Quarter showing signage, night scenes and street scenes

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Pacific Beach Park showing a beach

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Belmont Park showing rides and a garden

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Ocean Beach

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach Pier and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

Top Serra Mesa Hotel Reviews

Paradise Point Resort & Spa

Paradise Point Resort & Spa

10/10 Excellent
"Great experience "
Jennifer 2-night trip
Posted 1 day ago
Paradise Point Resort & Spa

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighborhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

How many hotels will I be able to find in the Serra Mesa area?

Expedia has 34 hotels and other accommodations in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, you'll find most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the top deals on offer in Serra Mesa.

Where can I learn more about changing or cancelling my trip to Serra Mesa?

For more information about picking new dates or cancelling your trip to Serra Mesa, click here.

What can I see and do in this San Diego neighborhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.