Serra Mesa Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to NT$5,067 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Serra Mesa

Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Serra Mesa
US Grant Hotel

Downtown San Diego

3 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Find hotels in Downtown San Diego

Serra Mesa Hotel Deals

Hotel del Coronado, Curio Collection by Hilton

Hotel del Coronado, Curio Collection by Hilton

4 out of 5
1500 Orange Ave Coronado CA
Fully refundableReserve now, pay when you stay
The price is NT$11,963 per night from Dec 15 to Dec 16
NT$11,963
NT$15,021 total
Dec 15 - Dec 16
includes taxes & fees
8.4/10 Very Good! (1,014 reviews)
Room was nice, walkability was great. On site amenities made the stay easy traveling with a toddler.

Reviewed on 2025/11/18

Hotel del Coronado, Curio Collection by Hilton
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
The price is NT$3,573 per night from Dec 7 to Dec 8
NT$3,573
NT$4,107 total
Dec 7 - Dec 8
includes taxes & fees
8/10 Very Good! (2,203 reviews)
Room was excellent, clean and friendly staff at all times of the day

Reviewed on 2025/11/24

Hilton San Diego Mission Valley
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
The price is NT$3,928 per night from Nov 30 to Dec 1
NT$3,928
NT$4,515 total
Nov 30 - Dec 1
includes taxes & fees
9/10 Wonderful! (2,967 reviews)
I had an amazing time at the hotel. The room was spacious and comfortable, and the staff was incredibly friendly and helpful. The restaurant there served delicious food that was a highlight of my stay.

Reviewed on 2025/11/27

Legacy Resort Hotel & Spa
See all 9,035 properties in Serra Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Serra Mesa vacation package cost?
Be ready to book, because a trip to Serra Mesa starts from just . When you bundle your hotels, flights and car rentals into a package, you'll land the lowest prices.
How do I get a cheap travel package to Serra Mesa?
One of the simplest ways to save dollars (and time) is to bundle your bookings with Expedia. Flights, hotels, activities and rental cars — we've got everything you need. Pick the combination that best suits you and watch your savings pile up. Of course, a travel package is never one-size-fits-all. That's why we offer more than 550 partner airlines and 1,000,000 hotel options worldwide, which lets you customize your Serra Mesa vacation.
Where should I stay in Serra Mesa?
Most visitors to Serra Mesa put both San Diego Zoo and Balboa Park on their itineraries. Why not go for a hotel that's close to these fantastic attractions?
What are the top hotels in Serra Mesa?
Get your escape off to an excellent start by locking in a room at Central Location - 3br/2ba. Stay Weekly. Clean. It's one of most sought-after properties in Serra Mesa. Another comfortable option is Newly Remodeled Beautiful Beach Bound And Centrally Located San Diego Home.
How far in advance should I book my Serra Mesa vacation?
It's difficult to pick the best time for airfares, but we normally say the earlier, the better. Most international flights on Expedia become available up to 12 months in advance. If you're booking late, fear not. Budget prices appear from time to time just weeks before departure dates.
What does an Expedia Serra Mesa travel package include?
From flights and hotels to rental cars, Expedia can help you craft a Serra Mesa package that's perfect for you. Vacationing for a few weeks? Consider a flight, hotel and rental car bundle. If your break is short, a flight and hotel deal could be what you're after. Experiences can also be added once you've made your booking. Our travel packages make it a cinch to plan and save.
What should I know before booking a Serra Mesa travel package?
You can save a tidy sum by combining your hotels, airfares and rental cars. Once you've made your booking, you can add on things like day tours or experiences. Your next unforgettable vacation is only a few clicks away.
Can I choose my airline with a Serra Mesa Expedia vacation package?
With a vacation package, you're the one in charge. Whether you'd like to fly to Serra Mesa in economy or first class, simply choose from the available airline options. Expedia has access to over 550 partner airlines all over the world.
If I'm not able to travel, can I cancel my Serra Mesa vacation package?
Plans can change in the blink of an eye, so yes. You may be able to cancel or alter your Serra Mesa vacation package at no cost if you've booked in the last 24 hours. For bookings made more than 24 hours ago, you can still make the necessary changes, but your car rental company, hotel or airline may impose a charge. Want more information? Check out our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.

Discover the most popular places to visit in Serra Mesa

San Diego Zoo featuring landscape views, zoo animals and a pond

San Diego Zoo

See nature up-close and personal at one of the country’s largest and most educational zoos.

San Diego Zoo
San Diego Convention Center

San Diego Convention Center

During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's acclaimed art scene and entertainment choices.

San Diego Convention Center
Disney Wonder Cruise Ship. Halloween on the High Seas. #lifeatexpedia #golden

Port of San Diego

Explore the waterfront in San Diego with a trip to Port of San Diego. Wander the seaside and beautiful beaches in the area.

Port of San Diego
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.