Top Uptown Hotels

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Our top choices for Uptown hotels

A spacious lobby with a high ceiling, large windows, and a variety of seating options including sofas and chairs.

1. Drury Inn & Suites St. Louis Collinsville

Eastport, 2.6 km from Uptown

Amanda

NT$3,673 total

includes taxes & fees

Nov 22 - Nov 23

A reception area with a wooden reception desk, a stone wall with a clock, and framed pictures on the wall.

2. Comfort Inn Collinsville near St. Louis

Eastport, 2.7 km from Uptown

Chessy

NT$3,718 total

includes taxes & fees

Nov 26 - Nov 27

A lobby with a central table displaying vases, a stone wall with mirrors, and a seating area with sofas and chairs.

3. DoubleTree by Hilton Collinsville - St. Louis

Eastport, 2.6 km from Uptown

katie

NT$4,014 total

includes taxes & fees

Dec 1 - Dec 2

A hotel room with two beds, a desk, a chair, and a TV.

4. Hampton Inn Collinsville

Eastport, 2.7 km from Uptown

Jeffrey

NT$3,785 total

includes taxes & fees

Nov 22 - Nov 23

A multi-story hotel with a covered entrance, stone pillars, and a parking lot.

5. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

Eastport, 2.9 km from Uptown

Paul

NT$3,473 total

includes taxes & fees

Nov 22 - Nov 23

A modern hotel lobby with a central dining area, seating arrangements, and a television screen.

6. Holiday Inn Express Troy by IHG

10 km from Uptown

Tammy

NT$3,980 total

includes taxes & fees

Nov 29 - Nov 30

A modern hotel room with a large bed, a blue chair, and a wall-mounted TV.

7. Days Inn by Wyndham Collinsville/St. Louis

Eastport, 2.7 km from Uptown

Gary

NT$2,385 total

includes taxes & fees

Nov 19 - Nov 20

A modern indoor pool area with a blue ceiling, large windows, and a pool with a metal ladder.

8. Hampton Inn O'Fallon

10.9 km from Uptown

Edmond

NT$4,299 total

includes taxes & fees

Nov 15 - Nov 16

A lobby with checkered armchairs, a reception desk, a plant, and a tiled floor.

9. Americas Best Value Inn Collinsville St. Louis

2.3 km from Uptown

Shewanna

NT$2,425 total

includes taxes & fees

Nov 9 - Nov 10

A modern living room with a sofa, chairs, a coffee station, and a dining area.

10. Best Western St. Louis Fairview Heights

7.3 km from Uptown

Jacob

NT$3,250 total

includes taxes & fees

Nov 2 - Nov 3

A modern lounge area with a sectional sofa, ottomans, and a round table.

11. Drury Inn & Suites St. Louis Fairview Heights

7.2 km from Uptown

Christopher

NT$3,314 total

includes taxes & fees

Nov 23 - Nov 24

An outdoor patio with tables and chairs, a brick building, and a parking lot in the background.

12. Fairfield Inn & Suites by Marriott O'Fallon, IL

11.4 km from Uptown

Mohamad

NT$5,185 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with a bed, two bedside lamps, a cityscape painting, a wooden headboard, and a brown chair.

13. Super 8 by Wyndham Collinsville St. Louis

Eastport, 2.8 km from Uptown

stephen

NT$2,661 total

includes taxes & fees

Nov 2 - Nov 3

A modern hotel lobby with a sofa, chairs, a round table, and a decorative wall with geometric patterns.

14. Holiday Inn St. Louis Fairview Heights by IHG

7.3 km from Uptown

Julia

NT$4,088 total

includes taxes & fees

Nov 29 - Nov 30

A hotel lobby with blue seating, a flat-screen TV, and a fireplace.

15. Comfort Inn Edwardsville - St. Louis

10.9 km from Uptown

Christina

NT$3,058 total

includes taxes & fees

Nov 29 - Nov 30

A Holiday Inn Express & Suites hotel with a covered entrance and a brick facade.

16. Holiday Inn Express & Suites O'Fallon/Shiloh by IHG

11.9 km from Uptown

Rafal

NT$3,437 total

includes taxes & fees

Nov 29 - Nov 30

An outdoor seating area with a fire feature, cushioned seating, and a bar area.

17. TownePlace Suites by Marriott St. Louis O'Fallon

11.1 km from Uptown

Bethany

NT$4,944 total

includes taxes & fees

Nov 22 - Nov 23

A spacious lobby with a fireplace, a large painting, and multiple hanging light fixtures.

18. Hilton Garden Inn St. Louis Shiloh/O'Fallon IL

10.8 km from Uptown

Jeremy

NT$4,138 total

includes taxes & fees

Nov 9 - Nov 10

A hotel room with two beds, each with a headboard, bedside tables, lamps, and a desk with a chair.

19. Econo Lodge Inn & Suites Fairview Heights - St. Louis

7.2 km from Uptown

Linda

NT$2,355 total

includes taxes & fees

Nov 29 - Nov 30

A lobby with a blue sofa, patterned cushions, a reception desk, and a mural of a moon and arch.

20. La Quinta Inn & Suites by Wyndham Pontoon Beach

11.2 km from Uptown

Walter

NT$4,827 total

includes taxes & fees

Nov 1 - Nov 2

View all properties

Compare popular hotels in Uptown

Property	Property class	Guest rating
Drury Inn & Suites St. Louis Collinsville	3.0 star property	9.6 Exceptional 1,000 reviews	View
Holiday Inn Express Troy by IHG	2.5 star property	9.4 Exceptional 844 reviews	View
Comfort Inn Collinsville near St. Louis	2.5 star property	8.6 Excellent 1,000 reviews	View
Hampton Inn O'Fallon	2.5 star property	9.2 Wonderful 885 reviews	View
DoubleTree by Hilton Collinsville - St. Louis	4.0 star property	8.2 Very good 1,001 reviews	View

Where to stay in Uptown

Find the best Uptown areas and neighborhoods for the activities you enjoy most.

An aerial view of a city with a prominent river, a large bridge, and surrounding buildings.

Eastport

If you're spending some time in Eastport, Splash City Family Waterpark and Gateway Conference Center are top sights worth seeing.

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Mulberry Hills

While Mulberry Hills isn't home to many top sights, World's Largest Catsup Bottle and Kruta Bakery are some notable places to visit nearby.

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A large, historic building with arched windows and a prominent corner entrance.

Historic Downtown Collinsville

While Historic Downtown Collinsville isn't home to many top sights, World's Largest Catsup Bottle and Kruta Bakery are some notable places to visit nearby.

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Top Uptown Hotel Reviews

Forest Park Hotel by MDR

10/10 Excellent

"n/a"

Pear Tree Inn St. Louis Near Union Station

8/10 Good

"During snack time a worker used his dirty hands to pick up tortilla chips off the counter and put them back in the bowl with other chips. I asked him if he could replace the whole bowl of tortilla chips due to contamination. He said “what’s the issue? I’m going to put fresh ones on top!” I asked for a manager and she told him to replace the whole bowl of tortilla chips. I witnessed him use his HAND multiple times to swipe crumps off the counter into his other hand. Totally unacceptable. I did not eat anything that was placed out for 5:30 snack nor breakfast!!"

21C Museum Hotel St Louis

10/10 Excellent

"Location was great, art was fun, loved the little coffee shop (Mike at the coffee shop especially was great so kind!) and the basement sauna. Hot tub was closed while I was there, the chocolates served in the room were old tasting and at check-in I watched the front desk give the couple ahead of me great customer service and then received really mid service in comparison. I would stay here again but those little things were off."

Frequently asked questions

What is Uptown like?

Travelers to the Uptown neighborhood in Collinsville will be sure to enjoy their stay. Are you looking for Uptown travel tips? Be sure to check out Kruta Bakery and World's Largest Catsup Bottle while you're in the neighborhood.

If I need to cancel my hotel reservation in Uptown, will I receive a refund?

Yes! Most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Add dates, click "Search", then you can use the "fully refundable" filter to review the top deals on offer in Uptown.

Where can I learn more about changing or cancelling my trip to Uptown?

For additional details about picking new dates or cancelling your trip to Uptown, click here.

What is there to do in this Collinsville neighborhood?

A few attractions you might want to check out while you're in Uptown are Kruta Bakery and World's Largest Catsup Bottle. While you're out sightseeing, Gateway Conference Center and Gateway Fun Park are a couple of additional sights to visit in Collinsville.

Find hotels in Uptown, Collinsville

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Check prices for these dates

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Our top choices for Uptown hotels

1. Drury Inn & Suites St. Louis Collinsville

2. Comfort Inn Collinsville near St. Louis

3. DoubleTree by Hilton Collinsville - St. Louis

4. Hampton Inn Collinsville

5. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

6. Holiday Inn Express Troy by IHG

7. Days Inn by Wyndham Collinsville/St. Louis

8. Hampton Inn O'Fallon

9. Americas Best Value Inn Collinsville St. Louis

10. Best Western St. Louis Fairview Heights

11. Drury Inn & Suites St. Louis Fairview Heights

12. Fairfield Inn & Suites by Marriott O'Fallon, IL

13. Super 8 by Wyndham Collinsville St. Louis

14. Holiday Inn St. Louis Fairview Heights by IHG

15. Comfort Inn Edwardsville - St. Louis

16. Holiday Inn Express & Suites O'Fallon/Shiloh by IHG

17. TownePlace Suites by Marriott St. Louis O'Fallon

18. Hilton Garden Inn St. Louis Shiloh/O'Fallon IL

19. Econo Lodge Inn & Suites Fairview Heights - St. Louis

20. La Quinta Inn & Suites by Wyndham Pontoon Beach

Compare popular hotels in Uptown

Where to stay in Uptown

Eastport

Mulberry Hills

Historic Downtown Collinsville

Top Uptown Hotel Reviews

Forest Park Hotel by MDR

Frequently asked questions

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