A large, rusted metal bridge with blue railings and a 'Route 66' sign on the left.

Find Resorts & Hotels with Spas in Granite City, IL

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Check availability on Granite City Resorts & Hotels with Spas

Tonight
Sep 9 - Sep 10
Tomorrow
Sep 10 - Sep 11
This weekend
Sep 11 - Sep 13
Next weekend
Sep 18 - Sep 20

Our top choices for Granite City hotels with a spa

1. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
NT$4,527
NT$5,451 total
includes taxes & fees
Oct 4 - Oct 5
21C Museum Hotel St Louis

2. Truitt Hotel

Truitt Hotel
Lafayette Square
NT$5,295
NT$6,427 total
includes taxes & fees
Sep 10 - Sep 11
Truitt Hotel

3. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
NT$11,819
NT$13,819 total
includes taxes & fees
Sep 10 - Sep 11
Four Seasons Hotel St Louis

4. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
NT$5,177
NT$6,573 total
includes taxes & fees
Sep 27 - Sep 28
Ameristar Casino Resort and Spa

5. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
NT$17,320
NT$20,220 total
includes taxes & fees
Sep 20 - Sep 21
The Ritz-Carlton, St. Louis
View all properties

Choose what matters most at spa hotels in Granite City

Pool
Hot tub
Breakfast included
4 stars
5 stars

Find out more about Granite City

Top Granite City attractions for a relaxing vacation

Granite City, Illinois, offers a unique blend of relaxation and recreation for travelers seeking spa hotels. Start your journey at the nearby Cahokia Mounds, a UNESCO World Heritage site where you can explore ancient Native American earthworks and soak in the rich history of the region. After a day of exploration, unwind at a local spa hotel that may feature rejuvenating treatments inspired by the natural surroundings. If you’re in the mood for some outdoor fun, head to the scenic Wilson Park, where you can enjoy walking trails, picnicking, and even fishing, all while relishing the tranquil atmosphere. For art lovers, the nearby Historic Downtown Granite City offers quaint shops and galleries showcasing local artisans, perfect for a leisurely afternoon stroll. To top it off, consider staying at a hotel in the bustling area near the Mississippi River, where you can enjoy stunning views and easy access to both cultural activities and serene retreats. This combination of activities ensures a fulfilling getaway, allowing you to balance relaxation with adventure.

Top Granite City Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

8/10 Good
"I enjoyed my stay and will stay again."
khalil 1-night trip
Posted 8 hours ago
Clayton Plaza Hotel & Extended Stay
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent
"This hotel had an immaculate lobby, welcoming staff, security measures, large pool, clean spacious rooms, we picked a room with a view of the arch… so glad we picked this hotel"
Christin 1-night trip
Posted 9 hours ago
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

10/10 Excellent
"Awesome place ,clean , spacious and the staff was amazing.Definitely recommend"
Jeremy 2-night trip
Posted 10 hours ago
Hyatt Regency St. Louis at The Arch
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"Staff was very helpful and location e was great."
Tom 1-night trip
Posted 13 hours ago
Drury Plaza Hotel St. Louis at the Arch
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

10/10 Excellent
"Staff was friendly, building and rooms are amazing"
Mcdonald 3-night trip
Posted 18 hours ago
The Royal Sonesta Chase Park Plaza St. Louis
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

10/10 Excellent
"I'll tell you what. I visited the Ameristar for a fun weekend reunion with a long time college friend I hadn't seen in 30 years. We had plans to see the city, eat Italian on the Hill, go see the arch, see the city museum. But no...we left one time to go to a diner around the corner for breakfast and realized we had no desire to leave the hotel again. The food was amazing, the people (most likely regulars) were hilarious and fun. The pool was to die for. The bartenders at the pool were amazing and fun. We went to see the cover band at one of the bars on Saturday night and the place was PACKED. I think people were there just to go see them. Costumes, mullet wigs, 90's hair band...it was so fun. Will most DEFINITELY be back. Can't say enough good things. The rooms were HUGE and lovely. There were 17 pillows to choose from for your firmness desire (okay, maybe just 4 but still...). We had a blast."
Mary 3-night trip
Posted 22 hours ago
Ameristar Casino Resort and Spa
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent
"Great stuff and comfy beds and the hot tub was the best we ever had from a hotel before. Close to good BBQ spots."
Shawn 1-night trip
Posted 2 days ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Frequently asked questions

Looking for a spa hotel in Granite City?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the historical sites and shopping in Granite City—your day trip starts here. Enjoy the lakeside setting during your vacation. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your vacation.
What's there to see and do in Granite City?
Experience Granite City and visit Cahokia Mounds State Historic Site, Mississippi River, and Missouri River. If you have extra time while you're in the area, you might want to stop by Horseshoe Lake State Park and Six Mile Regional Library District - Johnson Road.
What is a Granite City spa hotel?
Spa hotels in Granite City provide lodging and have an on-site spa offering services like therapies and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

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