A large, rusted metal bridge with blue railings and a 'Route 66' sign on the left.

Find Resorts & Hotels with Spas in Granite City, IL

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on Granite City Resorts & Hotels with Spas

Tonight
Sep 16 - Sep 17
Tomorrow
Sep 17 - Sep 18
This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

Our top choices for Granite City hotels with a spa

1. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
NT$4,569
NT$5,501 total
includes taxes & fees
Oct 18 - Oct 19
21C Museum Hotel St Louis

2. Truitt Hotel

Truitt Hotel
Lafayette Square
NT$5,354
NT$6,500 total
includes taxes & fees
Sep 20 - Sep 21
Truitt Hotel

3. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
NT$11,927
NT$13,946 total
includes taxes & fees
Oct 4 - Oct 5
Four Seasons Hotel St Louis

4. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
NT$4,747
NT$6,075 total
includes taxes & fees
Oct 12 - Oct 13
Ameristar Casino Resort and Spa

5. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
NT$17,461
NT$20,385 total
includes taxes & fees
Sep 20 - Sep 21
The Ritz-Carlton, St. Louis
View all properties

Choose what matters most at spa hotels in Granite City

Pool
Hot tub
Breakfast included
4 stars
5 stars

Find out more about Granite City

Top Granite City attractions for a relaxing vacation

Granite City, Illinois, offers a unique blend of relaxation and recreation for travelers seeking spa hotels. Start your journey at the nearby Cahokia Mounds, a UNESCO World Heritage site where you can explore ancient Native American earthworks and soak in the rich history of the region. After a day of exploration, unwind at a local spa hotel that may feature rejuvenating treatments inspired by the natural surroundings. If you’re in the mood for some outdoor fun, head to the scenic Wilson Park, where you can enjoy walking trails, picnicking, and even fishing, all while relishing the tranquil atmosphere. For art lovers, the nearby Historic Downtown Granite City offers quaint shops and galleries showcasing local artisans, perfect for a leisurely afternoon stroll. To top it off, consider staying at a hotel in the bustling area near the Mississippi River, where you can enjoy stunning views and easy access to both cultural activities and serene retreats. This combination of activities ensures a fulfilling getaway, allowing you to balance relaxation with adventure.

Top Granite City Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

8/10 Good
"The staff was stellar, answered questions before I thought of them, knew the area and were efficient, housekeeping staff offered help and suggestions and were a highlight but front desk staff was great too. The parking garage was adequate, but parking before you checked in wasn't great (they offered a few 15 minute stalls and most folks clogged up the entrance area after that, so a bit cramped), but the garage itself wasn't bad. Room was clean, was were the public areas. Overall a nice stay!."
David 1-night trip
Posted 7 hours ago
Drury Plaza Hotel St. Louis Union Station
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"Great location, very clean. Highly recommend!"
Tina 1-night trip
Posted 9 hours ago
Drury Plaza Hotel St. Louis at the Arch
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent
"We will stay here again. Good bkfst, convenient. Nice pool & spa."
Penny 1-night trip
Posted 9 hours ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"We enjoyed the hotel. Lobby was beautiful and staff was helpful."
KYLE 1-night trip
Posted 10 hours ago
Clayton Plaza Hotel & Extended Stay
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent
"Room was clean and comfy. Breakfast was Delicious 😋"
Abel 1-night trip
Posted 1 day ago
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Frequently asked questions

Looking for a spa hotel in Granite City?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the historical sites and shopping in Granite City—your day trip starts here. Enjoy the lakeside setting during your vacation. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your vacation.
What's there to see and do in Granite City?
Experience Granite City and visit Cahokia Mounds State Historic Site, Mississippi River, and Missouri River. If you have extra time while you're in the area, you might want to stop by Horseshoe Lake State Park and Six Mile Regional Library District - Johnson Road.
What is a Granite City spa hotel?
Spa hotels in Granite City provide lodging and have an on-site spa offering services like therapies and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

Explore a world of travel with Expedia