Find hotels in Sant' Ambrogio, Florence

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Jan 7 - Jan 8
Tomorrow
Jan 8 - Jan 9
This weekend
Jan 9 - Jan 11
Next weekend
Jan 16 - Jan 18

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Sant' Ambrogio hotels

Lobby lounge
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World
5.0 star property
Sant' Ambrogio
10.0 out of 10, Exceptional, (14)
"This hotel was quite the find! The staff was amazing, attentive, respectful. The amenities, attention to detail, experience was amazing! We will definitely be back."
United States
Nicole
The price is NT$15,094
NT$17,194 total
includes taxes & fees
Jan 9 - Jan 10
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World
Rooftop terrace
Appartamento Puccini

Appartamento Puccini

Appartamento Puccini
Sant' Ambrogio
7.8 out of 10, Good, (76)
"The apartment is located perfectly"
Germany
Thomas
The price is NT$2,409
NT$3,828 total
includes taxes & fees
Feb 6 - Feb 7
Appartamento Puccini
Premium Apartment | Terrace/patio
Ciompi Prestige by Mmega

Ciompi Prestige by Mmega

Ciompi Prestige by Mmega
Sant' Ambrogio
9.0 out of 10, Wonderful, (2)
The price is NT$4,911
NT$9,525 total
includes taxes & fees
Jan 21 - Jan 22
Ciompi Prestige by Mmega
Comfort Apartment, 1 Bedroom, Non Smoking | Living area | Flat-screen TV
Santa Croce Place by Mmega

Santa Croce Place by Mmega

Santa Croce Place by Mmega
Sant' Ambrogio
6.8 out of 10, (5)
"The apartment was not kept well. Consumables like sugar, detergent etc. kept under lock and key. Mosquitoes were a hassle. The bathroom was very tiny. The bedroom is next to the road, so was very noisy. Although it is located at an excellent location."
India
Sachit
The price is NT$2,807
NT$6,473 total
includes taxes & fees
Jan 21 - Jan 22
Santa Croce Place by Mmega
City view
Iris Apartments by Mmega

Iris Apartments by Mmega

Iris Apartments by Mmega
Sant' Ambrogio
7.8 out of 10, Good, (12)
"Excellent location bit a bit noisy at night."
United States
Stephen
The price is NT$3,157
NT$6,859 total
includes taxes & fees
Jan 8 - Jan 9
Iris Apartments by Mmega
Deluxe Villa | Minibar, individually decorated, individually furnished, desk
Villa Tortorelli

Villa Tortorelli

Villa Tortorelli
Sant' Ambrogio
9.6 out of 10, Exceptional, (66)
"Beautiful property! Loved our stay here! "
United States
Olga
Villa Tortorelli
Apartment, 2 Bedrooms | 2 bedrooms, free WiFi, bed sheets
Borgo Pinti Cozy Flat 

Borgo Pinti Cozy Flat 

Borgo Pinti Cozy Flat 
Sant' Ambrogio
7.4 out of 10, Good, (3)
"Excellent property beyond our expectations. After a stressful day of traveling internationally, the key and entry taxed us. The key continued to be an issue for us (skeleton key with 4 locks). But otherwise, it's location and the property itself, awesome!"
United States
Stephanie
The price is NT$2,619
NT$5,906 total
includes taxes & fees
Jan 18 - Jan 19
Borgo Pinti Cozy Flat 
Presidential Suite, 1 Bedroom, Hot Tub, City View | 1 bedroom, premium bedding, down comforters, desk
Palazzo dei Ciompi Suites

Palazzo dei Ciompi Suites

Palazzo dei Ciompi Suites
Sant' Ambrogio
7.6 out of 10, Good, (392)
"worst customer service and guest support I have had ever experienced "
United States
Eduard
Palazzo dei Ciompi Suites
Deluxe Quadruple Room | Free WiFi
Residenza d'Epoca White Room

Residenza d'Epoca White Room

Residenza d'Epoca White Room
Sant' Ambrogio
7.4 out of 10, Good, (63)
"LOVED this place! It’s huge, cute, clean, centrally located, and has a super nice bathroom. Also has your own A/C unit which was awesome! Highly recommend especially for the price."
United States
Amelia
Residenza d'Epoca White Room
40-inch flat-screen TV with satellite channels
Dimora del Cardinale - Residenza d'epoca

Dimora del Cardinale - Residenza d'epoca

Dimora del Cardinale - Residenza d'epoca
Sant' Ambrogio
9.8 out of 10, Exceptional, (56)
"We had an easy check-in. Friendly staff welcomed us and we settled in quickly so we could enjoy the sites. We walked to all tours and restaurants. The restaurant next door was so good, we ate their twice! The property is well located to everything - food, shopping and more!"
United States
Stacey
The price is NT$2,648
NT$3,355 total
includes taxes & fees
Jan 18 - Jan 19
Dimora del Cardinale - Residenza d'epoca
Comfort Apartment | Living area | 32-inch flat-screen TV with digital channels
Don Giovanni by Mmega

Don Giovanni by Mmega

Don Giovanni by Mmega
Sant' Ambrogio
9.0 out of 10, Wonderful, (7)
"Perfect location Very clean Nicely appointed"
United States
Luanne
Don Giovanni by Mmega
Interior detail
Alfieri9

Alfieri9

Alfieri9
3.0 star property
Sant' Ambrogio
9.6 out of 10, Exceptional, (158)
"Hotel was in a nice quiet neighborhood, but still only a short walk to main attractions. The breakfast was excellent. Staff interactions were good."
United States
Colin
The price is NT$3,105
NT$3,858 total
includes taxes & fees
Feb 1 - Feb 2
Alfieri9
Garden
Locanda Orchidea - B&B

Locanda Orchidea - B&B

Locanda Orchidea - B&B
Sant' Ambrogio
9.2 out of 10, Wonderful, (233)
"Perfect location, superb room, + wonderful staff - a brilliant stay all round! "
United Kingdom
TARA
Locanda Orchidea - B&B
Bar (on property)
Hotel Villa Liana

Hotel Villa Liana

Hotel Villa Liana
3.0 star property
Sant' Ambrogio
8.6 out of 10, Excellent, (344)
"the breakfast was delicious!"
United States
Catherine
Hotel Villa Liana
Exterior
Wine Apartments Florence Colorino

Wine Apartments Florence Colorino

Wine Apartments Florence Colorino
Sant' Ambrogio
7.0 out of 10, Good, (2)
"It was clean and spacious."
United States
Joseph
Wine Apartments Florence Colorino
Interior entrance
Hotel D'Azeglio

Hotel D'Azeglio

Hotel D'Azeglio
2.0 star property
Sant' Ambrogio
7.8 out of 10, Good, (342)
"The place was walking distance very clean and quiet stuff very friendly a plus including breakfast "
United States
Beatriz
The price is NT$2,138
NT$2,683 total
includes taxes & fees
Jan 12 - Jan 13
Hotel D'Azeglio
Garden
Hotel Regency

Hotel Regency

Hotel Regency
5.0 star property
Sant' Ambrogio
9.4 out of 10, Exceptional, (443)
"Amazing stay as always. Beautiful hotel but the staff make it great. Feels like a home away from home. Perfect location that is easily walkable everywhere in the historic center."
United States
Aaron
The price is NT$8,900
NT$10,379 total
includes taxes & fees
Jan 16 - Jan 17
Hotel Regency
Interior entrance
Hotel Bavaria

Hotel Bavaria

Hotel Bavaria
1.0 star property
Sant' Ambrogio
8.2 out of 10, Very Good, (414)
"Good staff "
United States
Mohammed
The price is NT$2,098
NT$2,565 total
includes taxes & fees
Jan 8 - Jan 9
Hotel Bavaria
Restaurant
Hotel Bodoni

Hotel Bodoni

Hotel Bodoni
2.0 star property
Sant' Ambrogio
8.2 out of 10, Very Good, (792)
"Nice people and convenient location!!!!"
United States
julio
The price is NT$2,349
NT$2,915 total
includes taxes & fees
Jan 8 - Jan 9
Hotel Bodoni
View from property
B&B di Piazza del Duomo

B&B di Piazza del Duomo

B&B di Piazza del Duomo
Sant' Ambrogio
9.2 out of 10, Wonderful, (246)
"great location."
Australia
Ankur
The price is NT$4,618
NT$5,523 total
includes taxes & fees
Jan 26 - Jan 27
B&B di Piazza del Duomo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Sant' Ambrogio

Find the best Sant' Ambrogio areas and neighborhoods for the activities you enjoy most.
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo featuring heritage architecture and street scenes as well as a small group of people

Duomo

Piazza di Santa Maria Novella and Via de' Calzaiuoli are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

Santa Maria Novella which includes heritage architecture, a church or cathedral and street scenes

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Uffizi Gallery which includes street scenes as well as a large group of people

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

Piazza Santa Croce showing a city and street scenes

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Sant' Ambrogio Hotel Reviews

The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

10/10 Excellent
"Everything was wonderful. If I had a criticism it would be that the breakfast room was too cold. But that would hardly prevent us from visiting again!"
Jade 3-night trip
Posted 1 month ago
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

Frequently asked questions

What's it like in Sant' Ambrogio?
Guests are sure to enjoy their time checking out all that Florence's Sant' Ambrogio neighborhood has to offer. Be sure to check out Piazza Massimo D'Azeglio and Church of Santa Maria Maddalena dei Pazzi as part of your Sant' Ambrogio travel plans.
What's the best accommodation in Sant' Ambrogio?
Based on Expedia customer reviews, Alfieri9 is the highest ranked property in Sant' Ambrogio. This hotel is a short 15-minute walk from Piazza del Duomo, and it offers free WiFi and valet parking. Other favorite options in the area include B&B di Piazza del Duomo and Hotel Regency.
How many hotels will I find in Sant' Ambrogio?
If you're searching for places to stay in Florence, Expedia has something to meet your needs with 527 Sant' Ambrogio hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Sant' Ambrogio, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to review top deals in Sant' Ambrogio.
Where can I learn more about changing or cancelling my trip to Sant' Ambrogio?
To find more details about rescheduling or cancelling your trip to Sant' Ambrogio, head over to our customer service page.
What is there to do around this Florence neighborhood?
Landmarks in Sant' Ambrogio that you won't want to miss include Great Synagogue of Florence and Church of Santa Maria Maddalena dei Pazzi. Piazza Massimo D'Azeglio and Mercato di Sant'Ambrogio are also a couple of places to visit in the neighborhood. A few places to visit in the area around Sant' Ambrogio include Piazza di Santa Maria Novella, Jewish Museum, and FiesoleBike Day Tours. When you're sightseeing in Florence, Galleria d'Arte Civico69 and Teatro della Pergola are also worth a stop.

Explore a world of travel with Expedia