Find hotels in Medical Center District, San Antonio

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Medical Center District hotels

Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,003 reviews)
"Very comfortable, everything was clean, great staff and it’s near all the important hospitals. "
United States
Jesus
The price is NT$2,351
NT$2,744 total
includes taxes & fees
Mar 1 - Mar 2
Fairfield Inn & Suites by Marriott San Antonio Medical Center

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very Good, (3,200 reviews)
"Great stay with nice breakfast and clean rooms "
United States
Leah
The price is NT$2,791
NT$3,298 total
includes taxes & fees
Feb 22 - Feb 23
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,002 reviews)
"Clean rooms @ friendly staff!"
United States
LaTishe
The price is NT$2,797
NT$3,306 total
includes taxes & fees
Mar 1 - Mar 2
Courtyard by Marriott Medical Center San Antonio

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,012 reviews)
"Courteous staff, clean room, safe location "
United States
Danica
The price is NT$3,179
NT$3,777 total
includes taxes & fees
Mar 21 - Mar 22
San Antonio Marriott Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,278 reviews)
"Excellent awesome place we love it Room was super clean staff super nice "
United States
Maria
The price is NT$2,828
NT$3,343 total
includes taxes & fees
Feb 24 - Feb 25
Drury Inn & Suites San Antonio Northwest Medical Center

Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.4 out of 10, Good, (283 reviews)
"Room was good standings, staff was friendly "
United States
Luis
Atria Inn & Suites

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX
3.0 star property
Medical Center District
6.8 out of 10, (1,001 reviews)
"Great place , front desk are helpful and friendly. Safe place to stay ."
United States
Justin
The price is NT$1,909
NT$2,228 total
includes taxes & fees
Mar 22 - Mar 23
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (247 reviews)
"Good stay and safe area"
United States
Mario
The price is NT$1,596
NT$1,864 total
includes taxes & fees
Feb 22 - Feb 23
Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, TX - Medical Center

Studio 6 San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (827 reviews)
"Staff was great, very clean rooom"
United States
Laura
The price is NT$1,602
NT$1,957 total
includes taxes & fees
Mar 1 - Mar 2
Studio 6 San Antonio, TX - Medical Center

Park Inn by Radisson

Park Inn by Radisson
2.0 star property
Medical Center District
7.2 out of 10, Good, (1,001 reviews)
"Room was spotless and bed was great."
United States
Pamela
The price is NT$2,007
NT$2,344 total
includes taxes & fees
Mar 5 - Mar 6
Park Inn by Radisson

OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.2 out of 10, Good, (228 reviews)
"Staff was courteous and professional and the room is nice."
United States
Thomas
The price is NT$1,997
NT$2,552 total
includes taxes & fees
Feb 21 - Feb 22
OYO Inn & Suites Medical Center San Antonio

Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (1,000 reviews)
"Room was clean, beds comfortable, staff extremely friendly and helpful "
United States
Kathleen
The price is NT$1,648
NT$1,949 total
includes taxes & fees
Feb 22 - Feb 23
Motel 6 San Antonio, TX - Northwest Medical Center

Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.0 out of 10, (508 reviews)
"Was good, but there is no one overnight, security doesn't answer and the opening person was almost an hour late. "
United States
Michelle
The price is NT$1,366
NT$1,615 total
includes taxes & fees
Mar 2 - Mar 3
Flex Studios

La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
3.0 star property
9 km from Medical Center District
9.2 out of 10, Wonderful, (1,150 reviews)
"It was a great stay."
United States
Bridget
The price is NT$2,613
NT$3,050 total
includes taxes & fees
Mar 1 - Mar 2
La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
3.5 star property
Far West Side, 11.3 km from Medical Center District
9.0 out of 10, Wonderful, (1,458 reviews)
"Great Stay"
United States
Melissa
The price is NT$2,954
NT$4,795 total
includes taxes & fees
Feb 23 - Feb 24
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Courtyard by Marriott San Antonio SeaWorld - Westover Hills

Courtyard by Marriott San Antonio SeaWorld - Westover Hills
3.0 star property
Far West Side, 12.1 km from Medical Center District
8.6 out of 10, Excellent, (1,135 reviews)
"the room was very clean and the staff was very friendly. Its was convenient to Seaworld and shopping destinations."
United States
Evelyn
The price is NT$3,192
NT$3,793 total
includes taxes & fees
Feb 23 - Feb 24
Courtyard by Marriott San Antonio SeaWorld - Westover Hills

Hilton San Antonio Hill Country

Hilton San Antonio Hill Country
4.0 star property
Far West Side, 11.6 km from Medical Center District
8.6 out of 10, Excellent, (1,063 reviews)
"The room was very clean, room service was great. Perfect staycation."
United States
Christie
The price is NT$2,843
NT$4,606 total
includes taxes & fees
Mar 1 - Mar 2
Hilton San Antonio Hill Country

Best Western near Lackland AFB/SeaWorld

Best Western near Lackland AFB/SeaWorld
2.5 star property
Far West Side, 6.9 km from Medical Center District
8.0 out of 10, Very Good, (1,199 reviews)
"Great place to stay"
United States
Kala
The price is NT$1,760
NT$2,055 total
includes taxes & fees
Feb 23 - Feb 24
Best Western near Lackland AFB/SeaWorld

Comfort Suites San Antonio Near Seaworld

Comfort Suites San Antonio Near Seaworld
2.5 star property
7 km from Medical Center District
7.8 out of 10, Good, (1,000 reviews)
"Great hotel for family stay."
United States
Luis
The price is NT$2,308
NT$2,695 total
includes taxes & fees
Mar 8 - Mar 9
Comfort Suites San Antonio Near Seaworld

Holiday Inn Express & Suites San Antonio - Brooks City Base by IHG

Holiday Inn Express & Suites San Antonio - Brooks City Base by IHG
2.5 star property
22.7 km from Medical Center District
8.6 out of 10, Excellent, (873 reviews)
"Great rooms nice location "
United States
Eva
The price is NT$3,004
NT$3,507 total
includes taxes & fees
Mar 1 - Mar 2
Holiday Inn Express & Suites San Antonio - Brooks City Base by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Medical Center District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Lobby
Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
9.0
Wonderful
1,003 reviews
View
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,278 reviews
View
Lobby
San Antonio Marriott Northwest Medical Center
3.5 star property
8.6
Excellent
1,012 reviews
View
Bar (on property)
Courtyard by Marriott Medical Center San Antonio
3.0 star property
8.8
Excellent
1,002 reviews
View
Free daily buffet breakfast
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
8.4
Very Good
3,200 reviews
View

Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Learn more about Medical Center District

Downtown San Antonio

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Uptown

While visiting Uptown, you might make a stop by sights like San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Fort Sam Houston

One reason travelers love spending time in Fort Sam Houston is the stunning river views, and United States Army Medical Department Museum is a top place to visit.

Arena District

If you're spending some time in Arena District, Frost Bank Center and Freeman Coliseum are top sights worth seeing.

Top Medical Center District Hotel Reviews

Frequently asked questions

What is Medical Center District like?
Travelers are sure to enjoy a stay in San Antonio's Medical Center District neighborhood. Are you looking for Medical Center District travel tips? Be sure to check out USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're in the neighborhood.
What's a favorite place to stay in Medical Center District?
Based on Expedia customer reviews, Drury Inn & Suites San Antonio Northwest Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and an indoor pool. Other favorite options in the area include Fairfield Inn & Suites by Marriott San Antonio Medical Center and Courtyard by Marriott Medical Center San Antonio.
How many hotels will I be able to find in Medical Center District?
Expedia has 120 hotels and other accommodations in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals in Medical Center District.
Where can I learn more about changing or cancelling my trip to Medical Center District?
For more information about changing or cancelling your trip to Medical Center District, go to https://www.expedia.com/service/.
What can I see and do in this San Antonio neighborhood?
USAA Corporate Office Headquarters, Cinemark San Antonio 16, and The San Antonio Art Institute are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.

Explore a world of travel with Expedia