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Nov 23 - Nov 24
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Discover Medical Center District hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Front of property
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3.0 star property
Medical Center District
8.6 out of 10, Excellent, (3069)
"Everything nice and clean Helpful staff Good location "
United States
Richard
The price is NT$2,616
NT$3,093 total
includes taxes & fees
Nov 24 - Nov 25
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Lobby
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1016)
"Nice property and comfortable beds."
United States
Geneva
The price is NT$2,671
NT$3,174 total
includes taxes & fees
Nov 24 - Nov 25
San Antonio Marriott Northwest Medical Center
Pool
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 star property
Medical Center District
9.0 out of 10, Wonderful, (1010)
"Breakfast is always great and hotel is always clean and relaxing "
United States
Michelle
The price is NT$2,608
NT$3,045 total
includes taxes & fees
Dec 1 - Dec 2
Fairfield Inn & Suites by Marriott San Antonio Medical Center
Reception
Park Inn by Radisson

Park Inn by Radisson

2.0 star property
Medical Center District
7.2 out of 10, Good, (1007)
"No frills, no hassles, clean, affordable and very convenient to Methodist Hospital."
United States
Tony
The price is NT$2,008
NT$2,344 total
includes taxes & fees
Nov 26 - Nov 27
Park Inn by Radisson
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1297)
"Great place to stay and visit "
United States
Harry
The price is NT$2,828
NT$3,342 total
includes taxes & fees
Nov 27 - Nov 28
Drury Inn & Suites San Antonio Northwest Medical Center
Exterior
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1004)
"Room was clean, staff was very friendly!!"
United States
Ray
The price is NT$2,797
NT$3,306 total
includes taxes & fees
Nov 30 - Dec 1
Courtyard by Marriott Medical Center San Antonio
Premium bedding, pillowtop beds, in-room safe, desk
SpringHill Suites by Marriott San Antonio Medical Center/NW

SpringHill Suites by Marriott San Antonio Medical Center/NW

3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1009)
"Staff was super friendly and the room was comfy and clean"
United States
Irving
The price is NT$3,174
NT$3,752 total
includes taxes & fees
Nov 24 - Nov 25
SpringHill Suites by Marriott San Antonio Medical Center/NW
Free daily on-the-go breakfast
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

3.0 star property
Medical Center District
6.8 out of 10, (1001)
"Easy check in"
United States
Violet
The price is NT$1,843
NT$2,152 total
includes taxes & fees
Dec 14 - Dec 15
Country Inn & Suites by Radisson, San Antonio Medical Center, TX
Desk, laptop workspace, blackout drapes, free WiFi
Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center

2.0 star property
Medical Center District
7.2 out of 10, Good, (207)
"Its was comfy, didnt have any troubles and had sooo many shopping stops around and dinning places"
United States
Heaven
The price is NT$1,665
NT$1,944 total
includes taxes & fees
Nov 24 - Nov 25
Studio 6 San Antonio, Tx - Northwest Medical Center
Free WiFi, bed sheets
Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center

2.0 star property
Medical Center District
6.0 out of 10, (1001)
"Really enjoyed our stay"
United States
ernest
The price is NT$1,433
NT$1,694 total
includes taxes & fees
Nov 24 - Nov 25
Motel 6 San Antonio, TX - Northwest Medical Center
Front of property
Atria Inn & Suites

Atria Inn & Suites

2.0 star property
Medical Center District
7.6 out of 10, Good, (270)
"Clean"
United States
Jesus
Atria Inn & Suites
Exterior
OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio

2.0 star property
Medical Center District
7.2 out of 10, Good, (221)
"Always great stay"
United States
Juan
The price is NT$1,697
NT$2,185 total
includes taxes & fees
Dec 7 - Dec 8
OYO Inn & Suites Medical Center San Antonio
1 bedroom, desk, laptop workspace, free WiFi
Studio 6 San Antonio, TX - Medical Center

Studio 6 San Antonio, TX - Medical Center

2.0 star property
Medical Center District
6.6 out of 10, (775)
"Clean room staff is really good real friendly I love being there"
United States
Matthew
The price is NT$1,459
NT$1,788 total
includes taxes & fees
Nov 24 - Nov 25
Studio 6 San Antonio, TX - Medical Center
Basic Room, Multiple Beds, Non Smoking | Desk, iron/ironing board, free WiFi, bed sheets
Flex Studios

Flex Studios

2.5 star property
Medical Center District
6.0 out of 10, (496)
"heb is nearby. "
United States
Sayeed
The price is NT$1,301
NT$1,538 total
includes taxes & fees
Nov 24 - Nov 25
Flex Studios
Water park
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

3.5 star property
Far West Side, 11.3 km from Medical Center District
9.0 out of 10, Wonderful, (1239)
"Awesome place to stay at "
United States
Diego
The price is NT$2,377
NT$4,108 total
includes taxes & fees
Dec 7 - Dec 8
Hyatt Vacation Club at Wild Oak Ranch, San Antonio
Game room
Riverwalk Plaza

Riverwalk Plaza

4.0 star property
12.3 km from Medical Center District
8.2 out of 10, Very Good, (6100)
"Yes beautiful hotel"
United States
MARYLUZ
Riverwalk Plaza
Lobby
Menger Hotel

Menger Hotel

3.5 star property
Downtown San Antonio, 12.6 km from Medical Center District
9.0 out of 10, Wonderful, (3547)
"Great place"
United States
Thomai
The price is NT$2,969
NT$3,510 total
includes taxes & fees
Dec 1 - Dec 2
Menger Hotel
Exterior
La Quinta Inn & Suites By Wyndham San Antonio At The Rim

La Quinta Inn & Suites By Wyndham San Antonio At The Rim

3.0 star property
11.9 km from Medical Center District
9.2 out of 10, Wonderful, (772)
"Great place to stay!! "
United States
Stacy
The price is NT$2,751
NT$3,212 total
includes taxes & fees
Dec 21 - Dec 22
La Quinta Inn & Suites By Wyndham San Antonio At The Rim
Indoor pool, outdoor pool
Courtyard by Marriott San Antonio SeaWorld - Westover Hills

Courtyard by Marriott San Antonio SeaWorld - Westover Hills

3.0 star property
Far West Side, 12.1 km from Medical Center District
8.6 out of 10, Excellent, (1065)
"good hotel"
United States
Deborah
The price is NT$2,911
NT$3,460 total
includes taxes & fees
Nov 24 - Nov 25
Courtyard by Marriott San Antonio SeaWorld - Westover Hills
Terrace/patio
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 star property
Downtown San Antonio, 12.1 km from Medical Center District
9.4 out of 10, Exceptional, (2151)
"Place was really great, great service and food, great location."
United States
Ward
The price is NT$3,291
NT$4,789 total
includes taxes & fees
Dec 7 - Dec 8
Hotel Valencia Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Learn more about Medical Center District
Downtown - Riverwalk which includes heritage architecture, boating and a river or creek

Downtown San Antonio

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Marion Koogler McNay Art Museum featuring art and interior views

Uptown

While visiting Uptown, you might make a stop by sights like Marion Koogler McNay Art Museum and Alamo Quarry Market.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Stone Oak

Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista while you're in town.

Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Dub Farris Athletic Complex.

Top Medical Center District Hotel Reviews

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

10/10 Excellent
"We had a wonderful experience as a first time guest. Nathan helped us tremendously with accommodations for our daughter’s 13th birthday and we received so many compliments from other parents. The pool and lazy river areas are stunning. We will definitely stay there again."
Corri 1-night trip
Posted 15 hours ago
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

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Frequently asked questions

What is Medical Center District like?
Travelers are sure to enjoy a stay in San Antonio's Medical Center District neighborhood. Are you looking for Medical Center District travel tips? Be sure to check out USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're in the neighborhood.
What's a favorite place to stay in Medical Center District?
Based on Expedia customer reviews, Drury Inn & Suites San Antonio Northwest Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and an indoor pool. Other favorite options in the area include SpringHill Suites by Marriott San Antonio Medical Center/NW and Fairfield Inn & Suites by Marriott San Antonio Medical Center.
How many hotels will I be able to find in Medical Center District?
Expedia has 123 hotels and other accommodations in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals in Medical Center District.
Where can I learn more about changing or cancelling my trip to Medical Center District?
For more information about changing or cancelling your trip to Medical Center District, go to https://www.expedia.com/service/.
What can I see and do in this San Antonio neighborhood?
USAA Corporate Office Headquarters, Cinemark San Antonio 16, and The San Antonio Art Institute are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.