Medical Center District, TX
San Antonio
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Stay near popular Medical Center District attractions
Medical Center District Hotel Deals
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,440 reviews)
"First time staying at a Drury Inn and loved it! Had no idea they had the free drinks and dinner buffet in the evening. Also noted it’s an indoor pool which we usually don’t prefer BUT this one was nice. Not muggy and hot inside the pool room like indoor pools usually are. All that together was a ..."
Reviewed on 2026/9/4
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
Book a stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness center, and WiFi (surcharge). Our guests praise the helpful ...
Hotel Valencia Riverwalk
150 E Houston St San Antonio TX
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
Riverwalk Plaza
100 Villita Street San Antonio TX
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
8/10 Very Good! (6,477 reviews)
"The staff were great and the hotel was in a great location to the riverwalk."
Reviewed on 2026/9/5
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Medical Center District
Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Learn more about Medical Center District
Downtown San Antonio
The stunning river views and popular shops are just a few highlights of Downtown San Antonio. Make a stop by Alamo or Aztec Theater while you're exploring the area.
Photo by Sarah C.
Open Photo by Sarah C.
Uptown
While visiting Uptown, you might make a stop by sights like Marion Koogler McNay Art Museum and Quarry Golf Club.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Northwest Side
While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Convocation Center.
Stone Oak
Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.
Medical Center District, TX
- Places of interest
- Medical Center District Hotels by Star Rating
- Hotels in top San Antonio neighborhoods
- Other vacations you might like
- University of Texas Health and Science Center at San Antonio
- CHRISTUS Santa Rosa Hospital - Medical Center
- River Walk
- Six Flags Fiesta Texas
- Henry B. González Convention Center
- Lackland Air Force Base
- Alamo
- Frost Bank Center
- Market Square
- San Antonio Zoo and Aquarium
- Lackland Air Force Base Visitor Center
- San Antonio River
- Natural Bridge Caverns
- North Star Mall
- La Cantera Golf Club
- Aquatica San Antonio Waterpark
Other Hotels near Medical Center District, San Antonio
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- Visit West End Historic District
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