The Best Hotels Closest to Kentucky Science Center in Louisville for 2026

Q: What's the area like around Louisville Science Center?

Louisville Science Center is located in an area of Louisville known for its beautiful river views, sporting events, and great live music scene. If you're looking for a convenient place to stay, check out the 292 hotels and other accommodations you'll find within a mile.

Q: What's the best place to stay near Louisville Science Center?

Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel .

Q: How many hotels can I expect to find close to Louisville Science Center?

Expedia has 292 hotels and other accommodations within a mile from Louisville Science Center.

Q: If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to review the best deals near Louisville Science Center.

Q: Where can I learn more about changing or cancelling my trip in the area near Louisville Science Center?

For more details about picking new dates or cancelling your stay near Louisville Science Center, click here .

Q: What can I see and do near Louisville Science Center?

21c Museum Hotel, Louisville Slugger Museum, and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row, and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse, and Headliners Music Hall.

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Our top choices for Kentucky Science Center hotels

A wooden staircase with a balustrade leading to a landing.

1. Market Street Inn

2.1 km from Kentucky Science Center

"Such a lovely stay at the Market Street Inn. A very charming, comfortable and feels like home kind of place. Carol and Steve are just the kindest owners. They were responsive and accommodating and always available if needed. We also loved meeting Lisa, who made breakfast each morning and took care of any housekeeping needs. We felt like we were treated as family and not just guests. The area and location is perfect, SUCH a cute little town. Plenty of restaurants, shops and entertainment within...

Ryan

NT$8,215 total

includes taxes & fees

Nov 16 - Nov 17

An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.

2. Hotel Distil, Autograph Collection

Downtown Louisville, 0.9 km from Kentucky Science Center

Athina

NT$7,795 total

includes taxes & fees

Nov 27 - Nov 28

A grand hotel lobby with ornate ceiling designs, a central staircase, and a dining area.

3. The Brown Hotel

Downtown Louisville, 1.2 km from Kentucky Science Center

Brianne

NT$4,123 total

includes taxes & fees

Nov 24 - Nov 25

A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

4. Homewood Suites by Hilton Louisville Downtown, KY

Downtown Louisville, 0.2 km from Kentucky Science Center

Jeanette

NT$4,409 total

includes taxes & fees

Nov 28 - Nov 29

A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

5. Omni Louisville Hotel

Downtown Louisville, 0.8 km from Kentucky Science Center

James

NT$6,878 total

includes taxes & fees

Nov 27 - Nov 28

A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

6. The Grady

Downtown Louisville, 0.2 km from Kentucky Science Center

Greg

NT$5,748 total

includes taxes & fees

Nov 23 - Nov 24

A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

7. DuPont Mansion Bed & Breakfast

Old Louisville, 2.8 km from Kentucky Science Center

Chris

NT$6,966 total

includes taxes & fees

Nov 15 - Nov 16

An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

8. Tempo By Hilton Louisville Downtown Nulu

Phoenix Hill, 2.1 km from Kentucky Science Center

Addison

NT$3,942 total

includes taxes & fees

Nov 25 - Nov 26

A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.

9. Stellar Suites

East Market District, 2.2 km from Kentucky Science Center

Kevin

NT$5,877 total

includes taxes & fees

Nov 19 - Nov 20

A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

10. 21c Museum Hotel Louisville

Downtown Louisville, < 0.1 km from Kentucky Science Center

Erick

NT$6,062 total

includes taxes & fees

Dec 6 - Dec 7

An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Downtown Louisville, 0.8 km from Kentucky Science Center

Paul

NT$5,691 total

includes taxes & fees

Nov 30 - Dec 1

A modern bar area with a circular bar, multiple seating options, and a large screen.

12. Cambria Hotel Louisville Downtown-Whiskey Row

Downtown Louisville, 1.2 km from Kentucky Science Center

Trista

NT$3,690 total

includes taxes & fees

Dec 13 - Dec 14

An outdoor seating area with wicker furniture and a fire pit.

13. Towneplace Suites By Marriott Louisville Downtown

Downtown Louisville, 0.3 km from Kentucky Science Center

Brandi

NT$3,752 total

includes taxes & fees

Nov 29 - Nov 30

A covered patio with a stone wall, a glass table, and a bench.

14. Central Park Bed & Breakfast

Old Louisville, 3 km from Kentucky Science Center

Stephen

NT$6,517 total

includes taxes & fees

Nov 16 - Nov 17

A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.

15. Moxy Louisville Downtown

Downtown Louisville, 0.9 km from Kentucky Science Center

Priscilla

NT$4,294 total

includes taxes & fees

Dec 14 - Dec 15

An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.

16. Aloft by Marriott Louisville Downtown

Downtown Louisville, 0.9 km from Kentucky Science Center

Anthony

NT$4,732 total

includes taxes & fees

Nov 27 - Nov 28

An outdoor dining area with a long table and wicker chairs, overhead lighting, and a view of the city.

17. Hotel Genevieve part of JdV by Hyatt

East Market District, 2.1 km from Kentucky Science Center

Brittney

NT$5,536 total

includes taxes & fees

Nov 19 - Nov 20

A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.

18. AC Hotel Louisville Downtown

East Market District, 2.1 km from Kentucky Science Center

Kevin

NT$5,536 total

includes taxes & fees

Nov 21 - Nov 22

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

19. Galt House Hotel Trademark Collection by Wyndham

Downtown Louisville, 0.5 km from Kentucky Science Center

Shun

NT$5,012 total

includes taxes & fees

Nov 25 - Nov 26

A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

20. Embassy Suites Louisville Downtown

Downtown Louisville, 0.8 km from Kentucky Science Center

Ernest P

NT$4,736 total

includes taxes & fees

Nov 23 - Nov 24

View all properties

Compare popular hotels close to Kentucky Science Center

Property	Property class	Guest rating
Market Street Inn	3.5 star property	9.8 Exceptional 127 reviews	View
Hotel Distil, Autograph Collection	4.0 star property	9.6 Exceptional 520 reviews	View
The Brown Hotel	4.5 star property	9.4 Exceptional 1,482 reviews	View
Homewood Suites by Hilton Louisville Downtown, KY	3.0 star property	9.4 Exceptional 1,004 reviews	View
Omni Louisville Hotel	4.0 star property	9.4 Exceptional 2,239 reviews	View

Top Kentucky Science Center Hotel Reviews

Holiday Inn Express & Suites Louisville Downtown by IHG

10/10 Excellent

"We got in late that evening and out early the next day. Check in was quick, parking garage was easy, quick bite for breakfast. Room was well maintained."

Homewood Suites by Hilton Louisville Downtown, KY

10/10 Excellent

"This was one of the best moderate price hotels in which we’ve ever stayed. The hotel was beautifully decorated; room was spacious and comfortable; staff were great and breakfast was exceptional with a huge variety with lots of toppings and touches. Location was perfect as well for our downtown walking exploration."

Embassy Suites Louisville Downtown

10/10 Excellent

"The cooked to order breakfast buffet on the third floor is outstanding. One of the best ever at an Embassy Suites that I have ever attended. The valet parking at $50 a night was very expensive, but it was adequate for us since we were doing a move and we had a loaded van of household items and were concerned about security and safety."

Holiday Inn Louisville Downtown by IHG

10/10 Excellent

"Property was clean and well kept. The valet parking did not make much sense to me though. I do not mind valeting my car and always opt to do so when traveling out of town if needed. However, most valet lots are private from public parking where the cars are not easily accessible. Here the valet lot is essentially an open lot I could have parked my car in on my own. Adding to this anybody could have gotten to or from our car at any point and time. Most nights we ended up parking our cars ourselves and then turning the keys over to the valet drivers, and the same thing when we needed to leave in the morning, we retrieved our keys from the valet driver and went and got out own vehicles, again entirely defeating the purpose of valet parking. Other than the parking there are no complaints about our stay."

Other attractions near Kentucky Science Center

A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)

Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

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Frequently asked questions

What's the area like around Louisville Science Center?

Louisville Science Center is located in an area of Louisville known for its beautiful river views, sporting events, and great live music scene. If you're looking for a convenient place to stay, check out the 292 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Louisville Science Center?

Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.

How many hotels can I expect to find close to Louisville Science Center?

Expedia has 292 hotels and other accommodations within a mile from Louisville Science Center.

If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to review the best deals near Louisville Science Center.

Where can I learn more about changing or cancelling my trip in the area near Louisville Science Center?

For more details about picking new dates or cancelling your stay near Louisville Science Center, click here.

What can I see and do near Louisville Science Center?

21c Museum Hotel, Louisville Slugger Museum, and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row, and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse, and Headliners Music Hall.

Find hotels near Kentucky Science Center, Louisville from NT$3,690

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Our top choices for Kentucky Science Center hotels

1. Market Street Inn

2. Hotel Distil, Autograph Collection

3. The Brown Hotel

4. Homewood Suites by Hilton Louisville Downtown, KY

5. Omni Louisville Hotel

6. The Grady

7. DuPont Mansion Bed & Breakfast

8. Tempo By Hilton Louisville Downtown Nulu

9. Stellar Suites

10. 21c Museum Hotel Louisville

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

12. Cambria Hotel Louisville Downtown-Whiskey Row

13. Towneplace Suites By Marriott Louisville Downtown

14. Central Park Bed & Breakfast

15. Moxy Louisville Downtown

16. Aloft by Marriott Louisville Downtown

17. Hotel Genevieve part of JdV by Hyatt

18. AC Hotel Louisville Downtown

19. Galt House Hotel Trademark Collection by Wyndham

20. Embassy Suites Louisville Downtown

Compare popular hotels close to Kentucky Science Center

Top Kentucky Science Center Hotel Reviews

Holiday Inn Express & Suites Louisville Downtown by IHG

Other attractions near Kentucky Science Center

Louisville Slugger Museum

Frequently asked questions

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