A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Find hotels in Defiance, MO from NT$2,461

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Sep 11 - Sep 12
Tomorrow
Sep 12 - Sep 13
This weekend
Sep 11 - Sep 13
Next weekend
Sep 18 - Sep 20

Filter by

Star rating

Guest rating

Our top choices for Defiance hotels

1. Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG
O'Fallon
United States
murray
NT$3,187
NT$3,759 total
includes taxes & fees
Sep 14 - Sep 15
Holiday Inn Express St. Louis West - O'Fallon by IHG

2. Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield
Chesterfield
United States
Jolisa
NT$3,936
NT$4,566 total
includes taxes & fees
Sep 20 - Sep 21
Hyatt Place St. Louis/Chesterfield

3. The Wildwood Hotel

The Wildwood Hotel
Wildwood
United States
Hailey
NT$2,609
NT$3,040 total
includes taxes & fees
Oct 12 - Oct 13
The Wildwood Hotel

4. Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
O'Fallon
United States
Linda
NT$2,601
NT$3,068 total
includes taxes & fees
Oct 4 - Oct 5
Sleep Inn & Suites O'Fallon MO - Technology Drive

5. Residence Inn by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield
Chesterfield
United States
Brandon
NT$5,963
NT$6,976 total
includes taxes & fees
Sep 19 - Sep 20
Residence Inn by Marriott St. Louis Chesterfield

6. Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
Chesterfield
United States
Cassandra
NT$4,090
NT$4,744 total
includes taxes & fees
Sep 22 - Sep 23
Drury Plaza Hotel St. Louis Chesterfield

7. Hilton Garden Inn St. Louis/O'Fallon MO

Hilton Garden Inn St. Louis/O'Fallon MO
O'Fallon
United States
Kassie
NT$3,415
NT$4,049 total
includes taxes & fees
Oct 11 - Oct 12
Hilton Garden Inn St. Louis/O'Fallon MO

8. Staybridge Suites O'Fallon Chesterfield by IHG

Staybridge Suites O'Fallon Chesterfield by IHG
O'Fallon
United States
Norman
NT$3,493
NT$4,120 total
includes taxes & fees
Oct 4 - Oct 5
Staybridge Suites O'Fallon Chesterfield by IHG

9. TownePlace Suites by Marriott St. Louis Chesterfield

TownePlace Suites by Marriott St. Louis Chesterfield
Chesterfield
United States
Bobbi jo
NT$4,038
NT$4,740 total
includes taxes & fees
Oct 5 - Oct 6
TownePlace Suites by Marriott St. Louis Chesterfield

10. Comfort Inn & Suites Chesterfield - St. Louis

Comfort Inn & Suites Chesterfield - St. Louis
Chesterfield
United States
Jessica
NT$2,565
NT$3,095 total
includes taxes & fees
Oct 4 - Oct 5
Comfort Inn & Suites Chesterfield - St. Louis

11. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
Chesterfield
United States
NEBAHAT
NT$3,376
NT$3,928 total
includes taxes & fees
Oct 11 - Oct 12
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

12. Hampton Inn & Suites St. Louis/Chesterfield

Hampton Inn & Suites St. Louis/Chesterfield
Chesterfield
United States
Vijay
NT$3,467
NT$4,034 total
includes taxes & fees
Sep 20 - Sep 21
Hampton Inn & Suites St. Louis/Chesterfield

13. Courtyard by Marriott St. Louis Chesterfield

Courtyard by Marriott St. Louis Chesterfield
Chesterfield
United States
Kelly
NT$3,663
NT$4,262 total
includes taxes & fees
Oct 4 - Oct 5
Courtyard by Marriott St. Louis Chesterfield

14. Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
St. Peters
United States
Melanie
NT$3,470
NT$3,989 total
includes taxes & fees
Sep 20 - Sep 21
Drury Inn & Suites St. Louis St. Peters

15. Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield
Chesterfield
United States
Alvin
NT$3,433
NT$3,982 total
includes taxes & fees
Sep 13 - Sep 14
Sonesta ES Suites St. Louis - Chesterfield

16. Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
Washington
United States
Michael Macumber
NT$4,059
NT$4,621 total
includes taxes & fees
Sep 13 - Sep 14
Best Western Plus Washington Hotel

17. Hampton Inn St. Louis Wentzville

Hampton Inn St. Louis Wentzville
Wentzville
United States
Jill
NT$4,113
NT$4,708 total
includes taxes & fees
Sep 28 - Sep 29
Hampton Inn St. Louis Wentzville

18. Residence Inn by Marriott O'Fallon

Residence Inn by Marriott O'Fallon
O'Fallon
United States
Gerald
NT$4,133
NT$4,875 total
includes taxes & fees
Oct 5 - Oct 6
Residence Inn by Marriott O'Fallon

19. Holiday Inn St. Louis West Six Flags by IHG

Holiday Inn St. Louis West Six Flags by IHG
Eureka
United States
Rob
NT$3,178
NT$3,703 total
includes taxes & fees
Sep 22 - Sep 23
Holiday Inn St. Louis West Six Flags by IHG

20. Comfort Inn Near Six Flags St. Louis

Comfort Inn Near Six Flags St. Louis
Pacific
United States
David
NT$3,115
NT$3,566 total
includes taxes & fees
Sep 22 - Sep 23
Comfort Inn Near Six Flags St. Louis
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Defiance attractions

A glass of red wine on a wooden table with a vineyard in the background.
Photo by Pages of Travel

Chandler Hill Vineyards

7.8/10 (7 reviews)
This elegant Missouri winery showcases local and California wines from its hillside setting. Savor varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.
See properties
A wooden dock extending into a pond with lily pads, surrounded by lush greenery and a clear blue sky.

August A. Busch Memorial Conservation Area

8.6/10 (7 reviews)
This sprawling conservation area features over 30 lakes and historic WWII bunkers amid diverse habitats. Explore well-maintained trails while watching for migratory birds and wildlife in their natural environment.
See properties

Sugar Creek Winery

8.0/10 (1 review)
Sip award-winning Missouri wines at this hillside vineyard along the scenic Katy Trail. Relax on covered decks with your own picnic while enjoying live weekend music and panoramic countryside views.
See properties

Historic Daniel Boone Home and Heritage Center

9.6/10 (4 reviews)
Step into the limestone home where Daniel Boone's son Nathan crafted a frontier masterpiece with seven fireplaces. Explore the surrounding historic village for an authentic glimpse into 19th-century pioneer life.
See properties

Yellow Farmhouse Winery

This boutique winery in Defiance, Missouri was known for its distinctive unfiltered wines and relaxed atmosphere. Visitors could enjoy tastings with live music while picnicking on scenic grounds with vineyard views.
See properties

Broemmelsiek Park

This 494-acre natural playground offers nine miles of trails through forests and around serene lakes. Attend a monthly stargazing event at the astronomy viewing area for a uniquely celestial park experience.
See properties

Matson Hill Park Trailhead

Wander through 475 acres of rugged forest terrain with challenging hiking paths and gravity-flow mountain bike trails. The historic 1830s Hays Home offers a glimpse into pioneer life amid the natural splendor.
See properties

Hamburg Trail Trailhead

This moderate 6.9-mile loop winds through the scenic Weldon Spring Conservation Area, connecting to the Katy Trail State Park. Spot native wildlife while traversing diverse landscapes of shaded woodlands and open fields.
See properties

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighboring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance
A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Top Defiance Hotel Reviews

Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield

10/10 Excellent
"Clean room, Super comfy beds, great staff, fulfilling breakfast options. Definitely will book again."
Shalin 1-night trip
Posted 6 hours ago
Hyatt Place St. Louis/Chesterfield
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

8/10 Good
"Staff were great!!! We always enjoy our time at this hotel! Wish the rooms were better sound proof though. Got woke up by loud guests."
Catherine 1-night trip
Posted 7 hours ago
Hollywood Casino & Hotel St. Louis
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

10/10 Excellent
"Excellent staff and service."
James 1-night trip
Posted 9 hours ago
Ameristar Casino Resort and Spa
Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield

8/10 Good
"We had the two bedroom loft and we enjoyed it very much. We loved having all of the extra space and having two bathrooms."
April 2-night trip
Posted 10 hours ago
Sonesta ES Suites St. Louis - Chesterfield
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

8/10 Good
"I have stayed at this hotel a few times. The value is good - a better than expected hotel for the price. There were 2 issues for this last stay. I had a room with an adjacent wall to the elevator area, and the elevator is very loud and clunky when the door opens and shuts. I could hear it all day and all night long (good thing I had good earplugs). Make sure to get a room away from the elevator. Also, the cable tv system is a mess. The channels don't match what the cable guide on the TV says nor what the icon in the corner of the screen says. Also, many of the channels they're supposed to have say "no signal." Not a huge deal but definitely annoying. A simple piece of paper in the room which lists the real channels would certainly help."
John 3-night trip
Posted 18 hours ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

10/10 Excellent
"Staff was all great"
Jeffrie 3-night trip
Posted 20 hours ago
Drury Plaza Hotel St. Louis Chesterfield
Fairfield Inn & Suites by Marriott St. Louis Chesterfield

Fairfield Inn & Suites by Marriott St. Louis Chesterfield

10/10 Excellent
"Wish every motel was like this one"
Sarah 1-night trip
Posted 1 day ago
Fairfield Inn & Suites by Marriott St. Louis Chesterfield
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

10/10 Excellent
"Clean and comfortable. There was some peeling wallpaper in the bathroom but I could overlook that because everything else was so nice."
Kimberley 1-night trip
Posted 3 days ago
Hampton Inn St. Charles St. Peters

More cheap stays in Defiance

Quality Inn Foristell

Quality Inn Foristell

12 Highway W Foristell MO
NT$2,634
NT$2,975 total
Sep 22 - Sep 23
includes taxes & fees
8.2/10 Very Good! (1,002 reviews)
Quality Inn Foristell
Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

1400 S 5th St St. Charles MO
NT$2,625
NT$3,017 total
Oct 4 - Oct 5
includes taxes & fees
Comfort Suites St Charles - St Louis
Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive

1147 Technology Drive O'Fallon MO
NT$2,601
NT$3,068 total
Oct 4 - Oct 5
includes taxes & fees
Sleep Inn & Suites O'Fallon MO - Technology Drive
Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

1310 Bass Pro Drive St. Charles MO
NT$2,832
NT$3,283 total
Sep 15 - Sep 16
includes taxes & fees
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

3720 W Clay St St. Charles MO
NT$3,079
NT$3,538 total
Oct 5 - Oct 6
includes taxes & fees
8/10 Very Good! (1,000 reviews)
Hampton Inn St. Charles St. Peters
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

1190 S Main St St. Charles MO
NT$3,977
NT$4,571 total
Oct 4 - Oct 5
includes taxes & fees
Country Inn & Suites by Radisson, St. Charles Historic District

Hotels in Defiance with star-rating

Find out more about Defiance

Top reasons to visit Defiance

  • Scenic Hiking Trails: Defiance offers access to beautiful hiking trails, perfect for outdoor enthusiasts looking to explore nature.
  • Charming Downtown: Stroll through downtown Defiance, featuring local shops and eateries that showcase the town's unique atmosphere.
  • Family-Friendly Attractions: Enjoy a variety of urban parks and amusement parks that cater to families and children.
  • Romantic Getaways: Defiance is ideal for couples seeking a romantic escape surrounded by picturesque landscapes.
  • Diverse Accommodations: Find comfortable lodging options, including pet-friendly and family-friendly hotels to suit every traveler's needs.

Find great hotels near Defiance

Discover a range of comfortable accommodations in Defiance, Missouri, perfect for every type of traveler. Whether you're seeking a pet-friendly hotel, a family-friendly getaway, or a business travel option, you'll find various choices to suit your needs. Explore the top hotels and available options in the area, ensuring a memorable stay in this charming destination.

  • Sonesta ES Suites St. Louis - Chesterfield: Embrace a home-away-from-home experience at Sonesta ES Suites, a 3-star hotel that caters to pet lovers. Located 19.3km from Defiance, this accommodation offers a welcoming environment for guests traveling with furry friends. With amenities like a pet-friendly policy, including variable fees and restrictions, the hotel ensures that your pets are comfortable, too. Guests appreciate the spacious suites equipped with fully functional kitchens, perfect for longer stays or families. Enjoy complimentary breakfast and a cozy atmosphere that makes this hotel an ideal choice for both leisure and business travelers.
  • The Wildwood Hotel: Nestled amidst nature, The Wildwood Hotel is a 3.5-star lodging just 14.5km from Defiance, perfect for those seeking an outdoor adventure. This hotel features a nature-themed ambiance, making it an excellent choice for business travelers and ski enthusiasts alike. Guests can take advantage of nearby ski shuttles and lifts, ensuring easy access to winter activities. The Wildwood Hotel boasts modern amenities, including a fitness center and meeting spaces, all while offering a warm and inviting atmosphere that reflects its picturesque surroundings.
  • Hyatt Place St. Louis/Chesterfield: A family-friendly choice, Hyatt Place St. Louis/Chesterfield is a 3-star hotel located 19.3km from Defiance. This hotel combines comfort and convenience, featuring spacious rooms and a variety of amenities suitable for both families and business travelers. With services tailored for children and a pet-friendly policy, including variable fees, it ensures a stress-free stay for everyone. Guests can enjoy a complimentary breakfast and a 24/7 market for snacks, making it a well-rounded option for those traveling with loved ones or on work trips.

Where to stay in and around Defiance

Defiance, Missouri, offers a delightful blend of outdoor adventures and romantic escapes. Stroll through downtown Defiance, where you can enjoy local shops and eateries, or take a leisurely walk to soak in the charming atmosphere. Nearby cities provide family-friendly and adventurous experiences, making it an ideal destination for any traveler seeking relaxation and exploration. Whether you're enjoying a relaxing break or uncovering historical gems, Defiance has something special for everyone.

  • Chesterfield: Located 19.3km from Defiance, Chesterfield is a vibrant city known for its family-friendly atmosphere and entertainment options. With a steady flow of visitors year-round, peak seasons occur in April and from June to July. Here, you'll find an array of activities, including theaters, an arcade adventure zone, and live music concerts. Local landmarks such as a theme park and sports facility stadium provide ample opportunities for fun and excitement, making Chesterfield a great destination for both relaxation and adventure.
  • Saint Albans: Just 6.4km from Defiance, Saint Albans offers a charming escape with its focus on outdoor activities and romantic experiences. Visitors flock to this city primarily in April, July, and September, appreciating its recreational areas and amusement parks. Notable attractions include a convention center, urban parks, and a picturesque lake that invites leisurely strolls or picnics. The blend of entertainment and natural beauty makes Saint Albans an ideal spot for travelers seeking a peaceful yet engaging getaway.
  • Hamburg: Nestled within the area of Defiance, Hamburg is a quaint village that welcomes visitors looking for outdoor adventures and family-oriented activities. With travel peaks from June to August, Hamburg offers beautiful parks and water features that are perfect for picnicking, hiking, or simply enjoying nature. The urban parks provide a serene environment for families to unwind and explore, making Hamburg a delightful addition to your travel itinerary.

Things to do in and around Defiance

Defiance, Missouri, is perfect for an outdoor, romantic getaway filled with memorable experiences. Enjoy scenic trail access and explore various hiking trails in this charming area. With its recreational spaces, you can engage in a variety of outdoor activities that promise to make your stay unforgettable. Whether you're seeking adventure or relaxation, Defiance offers a delightful blend of nature and entertainment for all visitors.

Shopping

In Defiance, you can shop at the St. Louis Premium Outlets, just 11.3km away, offering a lively atmosphere with various brands. If you're up for a drive, check out the Taubman Prestige Outlets, located 16.1km away, or the Wentzville Flea Market, 20.9km away, for unique finds.

Recreation

Broemmelsiek Park offers a tranquil escape with scenic walking trails and peaceful picnic spots, perfect for relaxation. For a blend of music and entertainment, The Factory hosts lively concerts just 16.1km away. If you enjoy sports, Missouri Bluffs Golf Course provides a beautiful outdoor setting for golf, located 11.3km from Defiance.

Adventure

At Hidden Valley Ski Resort, 14.5km from Defiance, enjoy exhilarating skiing and snowboarding on well-groomed slopes perfect for all skill levels. Hurricane Harbor, located 16.1km away, offers thrilling water rides and family-friendly attractions for a day of splashing fun. Explore Matson Hill Park Trailhead for scenic hiking amidst nature's beauty.

Nightlife

Experience the vibrant nightlife in Defiance with a visit to Chesterfield Sports Fusion for exciting arcade adventures, or enjoy the cultural charm at the New Jewish Theatre. For family fun, bounce over to Sky Zone Indoor Trampoline Park, just a short drive away.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Defiance

To save money on your trip to Defiance, Missouri, consider visiting during the off-peak months from December to February, when prices are lower. Book your stay on a Monday for the best rates, as Saturday is typically the most expensive day. Use Expedia to find budget-friendly accommodations by sorting prices from lowest to highest and exploring package deals that combine flights, hotels, and activities for extra savings. Look for flexible booking options and special offers to enhance your travel experience while keeping costs down.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Defiance are December to February, where the prices are slightly lower. This is in comparison to May to July, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Defiance is Monday. The most expensive day to stay in Defiance is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to customize your preferences, such as budget, desired location, and the type of hotel you’re looking for. To find the most affordable prices and special offers, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel reservation in Defiance with your flights and activities through an Expedia package.

Find the best attractions in and around Defiance

Defiance, Missouri, offers a perfect blend of outdoor adventures and romantic getaways. Visitors can explore a variety of attractions, including urban parks, national state parks, and amusement parks, making it ideal for families and those seeking a city experience. Whether you're looking to enjoy nature or entertain the kids, Defiance has something for everyone to create memorable vacation moments.

  • Six Flags St. Louis: Located 16.1km from Defiance, this amusement park offers thrilling rides and family-friendly attractions. Experience the excitement of roller coasters, live entertainment, and seasonal events, making it a perfect destination for adventure seekers of all ages.
  • August A. Busch Memorial Conservation Area: Situated within Defiance, this beautiful preserve is ideal for families looking to explore nature. Enjoy scenic trails, wildlife watching, and various outdoor excursions, all in a friendly atmosphere that encourages connection with the environment.
  • Historic Daniel Boone Home and Heritage Center: Also located in Defiance, this historic house immerses visitors in the rich culture and history of the region. Explore the preserved home of the legendary frontiersman and enjoy guided tours that showcase local heritage.

Best time to go to Defiance

The best time to visit Defiance can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Defiance falls in July, when visitor numbers are moderately high and weather is mostly sunny with light rain. The coolest average temperature in Defiance falls in January, visitor numbers are moderately low and weather is mostly cloudy with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January31.6°F (-0.2°C)Light RainMostly CloudyModerately LowSlightly Low
February34.7°F (1.5°C)Light RainMostly SunnyAverageSlightly Low
March46.4°F (8.0°C)Light RainMostly SunnyAverageAverage
April55.9°F (13.3°C)Light RainMostly SunnyModerately HighAverage
May66.2°F (19.0°C)Light RainMostly SunnyAverageSlightly High
June75.9°F (24.4°C)Light RainMostly SunnyAverageSlightly High
July79.0°F (26.1°C)Light RainMostly SunnyModerately HighSlightly High
August77.2°F (25.1°C)Light RainMostly SunnyAverageAverage
September70.9°F (21.6°C)Light RainMostly SunnyModerately HighAverage
October58.5°F (14.7°C)Light RainMostly SunnyAverageAverage
November46.2°F (7.9°C)Light RainMostly SunnyModerately LowAverage
December37.6°F (3.1°C)Light RainMostly SunnyModerately LowSlightly Low

The nearest major airports for your trip to Defiance

Visiting Defiance, Missouri, is convenient with its proximity to major airports. St. Louis Lambert International Airport (STL) is located 37.0km away, offering several nearby hotels such as The Ritz-Carlton, St. Louis, and Ameristar Casino Resort and Spa, both 11.3km from the airport. Another option is the Royal Sonesta Chase Park Plaza, situated 14.5km away. Alternatively, Spirit of St. Louis Airport (SUS) is only 11.3km from Defiance, with great accommodations like The Ritz-Carlton Sarasota, 4.8km away, and DoubleTree by Hilton Hotel St. Louis - Chesterfield, 6.4km away, ensuring a comfortable stay while you explore the area.

Frequently asked questions

What's the best place to stay in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, located 17.9 mi (28.8 km) from the heart of Defiance, is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are Hollywood Casino & Hotel St. Louis and Ameristar Casino Resort and Spa. See all available top hotels, or vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
Where can I learn more about changing or cancelling my trip to Defiance?
For more information about changing or cancelling your trip to Defiance, head over to our customer service page.
Where is the best hotel to stay with easy access to August A. Busch Memorial Conservation Area?
Sleep Inn & Suites O'Fallon MO - Technology Drive is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 2.6 mi (4.3 km) from August A. Busch Memorial Conservation Area. Other good options within a few miles include Hilton Garden Inn St. Louis/O'Fallon MO and Holiday Inn Express St. Louis West - O'Fallon, an IHG Hotel.
What about the best place to stay near Chandler Hill Vineyards?
One of the top choices for your stay is The Wildwood Hotel, located 10 mi (16.1 km) from Chandler Hill Vineyards, and this 3.5-star hotel offers free breakfast and an indoor pool.
What are some accommodations with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Features an indoor pool, an outdoor pool, and buffet. Ameristar Casino Resort and Spa and The Wildwood Hotel are two additional hotels that offer an onsite pool. View all hotels with pools in Defiance.
What's the best place to stay near Lambert-St. Louis International Airport (STL)?
Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.
What's it like to stay in Defiance?
Visitors can enjoy all that Defiance has to offer including the wineries and parks. Top sights in the area include St. Louis Union Station, Gateway Arch, and St. Louis Zoo. In Defiance, there are 19 hotels and other accommodations to choose from. Find out more about Defiance.
What is there to see in Defiance?
Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River, and Matson Hill Park Trailhead. A couple of additional sights to add to your agenda are Yellow Farmhouse Winery and Chandler Hill Vineyards. Check out what more to see and do in Expedia's Defiance guide.
What's the seasonal weather like in Defiance?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.

Explore a world of travel with Expedia