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Compare 830 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Crowne Plaza St. Louis Airport by IHG

3.5 star property
8.0 out of 10, Very Good, (1006)
"Great hotel and friendly staff "
The price is NT$3,411
NT$4,054 total
includes taxes & fees
Sep 2 - Sep 3
Crowne Plaza St. Louis Airport by IHG

MainStay Suites St Louis Airport

3.0 star property
8.2 out of 10, Very Good, (294)
"Was a good stay and nice room"
The price is NT$2,954
NT$3,524 total
includes taxes & fees
Aug 17 - Aug 18
MainStay Suites St Louis Airport

Comfort Inn St. Louis Airport

3.0 star property
8.4 out of 10, Very Good, (890)
"Good experience during our stay. "
The price is NT$2,686
NT$3,212 total
includes taxes & fees
Aug 14 - Aug 15
Comfort Inn St. Louis Airport

Embassy Suites by Hilton St. Louis Airport

3.5 star property
7.6 out of 10, Good, (1004)
"Enjoyed stay. The front desk staff was Excellent "
The price is NT$4,454
NT$5,267 total
includes taxes & fees
Aug 31 - Sep 1
Embassy Suites by Hilton St. Louis Airport

Extended Stay America Select Suites - St. Louis - Airport - Central

2.5 star property
7.0 out of 10, Good, (986)
"Clean and had good accommodation "
The price is NT$2,444
NT$2,930 total
includes taxes & fees
Aug 17 - Aug 18
Extended Stay America Select Suites - St. Louis - Airport - Central

Hilton St. Louis Frontenac

4.0 star property
8.8 out of 10, Excellent, (1008)
"Very friendly staff "
The price is NT$4,298
NT$5,006 total
includes taxes & fees
Sep 7 - Sep 8
Hilton St. Louis Frontenac

La Quinta Inn & Suites by Wyndham St. Louis Westport

3.0 star property
7.2 out of 10, Good, (1031)
"Great place"
The price is NT$2,558
NT$2,967 total
includes taxes & fees
Aug 24 - Aug 25
La Quinta Inn & Suites by Wyndham St. Louis Westport

Extended Stay America Select Suites - St. Louis - Westport - E Lackland Rd

2.5 star property
5.8 out of 10, (1000)
"The staff was wonderful and polite and helpful they need a raise!!!"
The price is NT$2,235
NT$2,592 total
includes taxes & fees
Aug 23 - Aug 24
Extended Stay America Select Suites - St. Louis - Westport - E Lackland Rd

Red Roof Inn St Louis - Westport/ Maryland Heights

2.0 star property
5.4 out of 10, (1004)
"I love how quiet it is here."
The price is NT$1,956
NT$2,269 total
includes taxes & fees
Aug 27 - Aug 28
Red Roof Inn St Louis - Westport/ Maryland Heights

The Lodge Hotel and Banquets

2.0 star property
5.0 out of 10, (372)
"I really liked being on the top floor. I like thr balconies around the property. The staff is very friendly and helpful. Will stay again. "
The price is NT$2,283
NT$2,743 total
includes taxes & fees
Aug 14 - Aug 15
The Lodge Hotel and Banquets

Courtyard by Marriott St Louis Westport Plaza

3.0 star property
8.8 out of 10, Excellent, (1004)
"We were just there to sleep but nice property."
The price is NT$3,381
NT$3,921 total
includes taxes & fees
Aug 22 - Aug 23
Courtyard by Marriott St Louis Westport Plaza

Residence Inn St Louis Westport

3.0 star property
9.2 out of 10, Wonderful, (411)
"Loved it "
The price is NT$4,405
NT$5,109 total
includes taxes & fees
Aug 24 - Aug 25
Residence Inn St Louis Westport

Fairfield Inn & Suites St Louis Westport

2.5 star property
9.2 out of 10, Wonderful, (786)
"Great place to stay. Friendly staff. Spacious room and hearty yummy breakfast. "
The price is NT$4,002
NT$4,642 total
includes taxes & fees
Aug 24 - Aug 25
Fairfield Inn & Suites St Louis Westport

Extended Stay America Select Suites St Louis Westport Craig

2.5 star property
6.4 out of 10, (758)
"The property was quiet, clean, and accessible. Since we used the local Metro Bus and rail, having a Bus stop almost in front of the Hotel."
The price is NT$2,235
NT$2,591 total
includes taxes & fees
Aug 24 - Aug 25
Extended Stay America Select Suites St Louis Westport Craig

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

2.5 star property
4.6 out of 10, (1007)
"Enjoyed staying "
The price is NT$2,009
NT$2,330 total
includes taxes & fees
Sep 1 - Sep 2
Days Inn and Suites by Wyndham St. Louis/Westport Plaza

Courtyard by Marriott St Louis Creve Coeur

3.0 star property
8.6 out of 10, Excellent, (1006)
"Very nice room & stay"
The price is NT$3,402
NT$3,955 total
includes taxes & fees
Aug 31 - Sep 1
Courtyard by Marriott St Louis Creve Coeur

Comfort Inn St. Louis - Westport Event Center

3.0 star property
7.0 out of 10, Good, (1005)
"Nice property "
The price is NT$2,452
NT$2,844 total
includes taxes & fees
Aug 24 - Aug 25
Comfort Inn St. Louis - Westport Event Center

Best Western Plus St. Louis West-Westport

2.5 star property
8.0 out of 10, Very Good, (1007)
"Breakfast was good and it was clean and comfortable bed "
The price is NT$2,659
NT$3,084 total
includes taxes & fees
Aug 18 - Aug 19
Best Western Plus St. Louis West-Westport

Hampton Inn St. Louis/Westport

2.5 star property
7.8 out of 10, Good, (952)
"We had a great stay for our 14th Wedding Anniversary! The only 2 complaint we had was the slow draining sink in the bathroom and the limited lighting in the bedroom! "
The price is NT$2,772
NT$3,215 total
includes taxes & fees
Aug 24 - Aug 25
Hampton Inn St. Louis/Westport

Staybridge Suites St Louis - Westport by IHG

3.0 star property
8.8 out of 10, Excellent, (595)
"Room was very spacious and clean, free breakfast was nice. Only "bad" part was the pool being under renovations so it was closed our whole stay. They did have vouchers to go to a pool at another hotel so all in all, great stay"
The price is NT$4,268
NT$4,950 total
includes taxes & fees
Sep 1 - Sep 2
Staybridge Suites St Louis - Westport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Learn more about Defiance

Trip time! Discover the wineries, parks, and history in Defiance.

Top Defiance Hotel Reviews

Frequently asked questions

What's the best place to stay in Defiance?

Hollywood Casino & Hotel St. Louis, located 18.1 mi (29.2 km) from the heart of Defiance, is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham and Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West. See all available top hotels, or vacation rentals in Defiance.

If I need to cancel my hotel reservation in Defiance, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.

Where can I learn more about changing or cancelling my trip to Defiance?

For more information about changing or cancelling your trip to Defiance, head over to our customer service page.

Where is the best hotel to stay with easy access to August A. Busch Memorial Conservation Area?

Sleep Inn & Suites O'Fallon MO - Technology Drive is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 2.6 mi (4.3 km) from August A. Busch Memorial Conservation Area. Other good options within a few miles include Hilton Garden Inn St. Louis/O'Fallon MO and Holiday Inn Express St. Louis West - O'Fallon, an IHG Hotel.

What about the best place to stay near Chandler Hill Vineyards?

One of the top choices for your stay is The Wildwood Hotel, located 10 mi (16.1 km) from Chandler Hill Vineyards, and this 3.5-star hotel offers free breakfast and an indoor pool.

What are some accommodations with pools in Defiance?
What's the best place to stay near Lambert-St. Louis International Airport (STL)?

Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.

What's it like to stay in Defiance?

Visitors can enjoy all that Defiance has to offer including the wineries and parks. Top sights in the area include St. Louis Union Station, Busch Stadium, and Gateway Arch. In Defiance, there are 20 hotels and other accommodations to choose from. Find out more about Defiance.

What is there to see in Defiance?

Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River, and Matson Hill Park Trailhead. A couple of additional sights to add to your agenda are Yellow Farmhouse Winery and Chandler Hill Vineyards. Check out what more to see and do in Expedia's Defiance guide.

What's the seasonal weather like in Defiance?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.