Visit Southern Indiana: 2026 Travel Guide for Southern Indiana, United States of America

Where to stay in Southern Indiana

Louisville Science Center featuring outdoor art

West Main Historic District

Boasting the largest collection of cast iron façades outside New York's SoHo district, this historic area features "Museum Row" with attractions like the Louisville Slugger Museum and Muhammad Ali Center.

Downtown Evansville

Dive into the cultural hub of Evansville, where you can catch a performance by the Evansville Philharmonic Orchestra at Victory Theatre or explore the Children's Museum of Evansville. Don't miss the LST-325 Museum and Ford Center nearby!

Cute Gastropub in downtown Louisville. The Burger had a pickled tomator on the bottom, I could have eaten a whole plate of those! #FoodieFinds

Portland

While visiting Portland, you might make a stop by sights like Portland Museum and Lannan Park Trailhead.

Whiteside Bakery built in 1908, later incorporated into the General Baking Co produced Bond Bread, a favorite of Hopalong Cassidy.

California

If you're spending some time in California, Ohio River Valley and Union Station are top sights worth seeing.

Shawnee

Though Shawnee might not have many top sights, you can venture to the surrounding area to see attractions like Frazier International History Museum and Louisville Slugger Museum.

Russell

If you're spending some time in Russell, Ohio River Valley and I. Willis Cole Residence are top sights worth seeing.

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Popular places to visit

Louisville Slugger Museum

Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

Holiday World and Splashin' Safari

Every day is a holiday at this fun-filled combination theme park and water park, where visitors of all ages can explore roller coasters, raft rides and wave pools.

Doc Crow's is perfect downtown spot for brisket and barbeque and has the tastiest drinks, especially the Man on Fire

Whiskey Row

Find out about the history of Louisville when you spend time at Whiskey Row. Attend a sporting event or simply enjoy the lively bars while you're in the area.

Muhammad Ali Center

One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.

Helped celebrate the Belle of Louisville's 100th birthday with a cruise up the Ohio River.

Louisville Waterfront Park

After visiting Louisville Waterfront Park, make a plan to see the other sights and activities in Louisville. Stroll along the area's riverfront or experience its lively festivals.