A modern glass building with a curved facade and a sign reading "The Kentucky Center".

Find Luxury Hotels in Southern Indiana

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on Southern Indiana Luxury Hotels

Tonight
Sep 15 - Sep 16
Tomorrow
Sep 16 - Sep 17
This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

Our top choices for Southern Indiana luxury hotels

1. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
NT$8,835
NT$10,395 total
includes taxes & fees
Sep 30 - Oct 1
Omni Louisville Hotel

2. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville
NT$7,530
NT$8,860 total
includes taxes & fees
Oct 4 - Oct 5
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

3. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville
NT$7,522
NT$8,850 total
includes taxes & fees
Oct 11 - Oct 12
Hotel Distil, Autograph Collection

4. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
Downtown Louisville
  • Upscale Louisville hotel features concierge, gourmet dining, and spacious suites with living areas.
NT$5,153
NT$6,064 total
includes taxes & fees
Sep 22 - Sep 23
Embassy Suites Louisville Downtown

5. Louisville Marriott Downtown

Louisville Marriott Downtown
Downtown Louisville
NT$6,805
NT$8,006 total
includes taxes & fees
Oct 4 - Oct 5
Louisville Marriott Downtown

6. The Grady

The Grady
Downtown Louisville
NT$5,553
NT$6,534 total
includes taxes & fees
Oct 11 - Oct 12
The Grady

7. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
  • Upscale riverside hotel features panoramic views, spa services, and gourmet dining in downtown Louisville.
NT$5,161
NT$6,072 total
includes taxes & fees
Oct 4 - Oct 5
Galt House Hotel Trademark Collection by Wyndham

8. Hyatt Regency Louisville

Hyatt Regency Louisville
Downtown Louisville
NT$5,759
NT$6,776 total
includes taxes & fees
Oct 4 - Oct 5
Hyatt Regency Louisville

9. The Brown Hotel

The Brown Hotel
Downtown Louisville
  • Elegantly designed spaces and refined comforts define this historic Louisville hotel offering a boutique feel in the city center.
NT$4,504
NT$5,300 total
includes taxes & fees
Sep 20 - Sep 21
The Brown Hotel

10. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
Downtown Louisville
  • Historic elegance meets modern luxury downtown, with pillowtop beds, designer toiletries, and 24-hour service.
NT$5,944
NT$6,994 total
includes taxes & fees
Sep 21 - Sep 22
Seelbach Hilton Louisville Downtown
View all properties

Find out more about Southern Indiana

Southern Indianaand its attractions for luxury travelers

Southern Indiana offers a unique blend of luxury and adventure for travelers. Begin your exploration at the iconic French Lick Resort, renowned for its stunning architecture and world-class spa services, where guests can indulge in pampering treatments or enjoy a round of golf on its championship courses. Next, visit the beautiful Hoosier National Forest, where you can enjoy guided horseback riding adventures or tranquil nature hikes, all while basking in the serene landscapes that this region has to offer. For those with a taste for culture, the historic town of New Harmony presents a perfect blend of art and history, featuring galleries and the picturesque Roofless Church, ideal for an afternoon stroll. Don’t miss the opportunity to savor the local wine at the Turtle Run Winery, known for its breathtaking vineyard views and exquisite tastings. Lastly, a stay in the charming town of Bloomington allows you to experience vibrant dining options and bustling arts scenes, complemented by luxury hotels that provide attentive service and exceptional amenities, ensuring a comfortable and memorable stay.

Top Southern Indiana Hotel Reviews

Howard Johnson by Wyndham Evansville East

Howard Johnson by Wyndham Evansville East

10/10 Excellent
"Bed comfy. Close to a lot of stuff. Pool was open until 11pm and deep end was 6 ft"
Jeremy 3-night trip
Posted 15 hours ago
Howard Johnson by Wyndham Evansville East
Hampton Inn New Albany Louisville West

Hampton Inn New Albany Louisville West

10/10 Excellent
"Typical clean Hampton Inn. Staff were excellent, plenty of parking, nice outdoor pool. Have absolutely no complaints."
George 1-night trip
Posted 21 hours ago
Hampton Inn New Albany Louisville West
Hyatt Select Louisville North

Hyatt Select Louisville North

8/10 Good
"Breakfast is not a real buffet more like a continental, which is fine for me I just need coffee in the morning. The room was nice and clean. I was on the first floor by the elevator so it was a lot of opening of doors and noise other then that I would have given it a 5/5"
Louis 1-night trip
Posted 2 days ago
Hyatt Select Louisville North

Explore a world of travel with Expedia