Southern Indiana Vacations

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Where to stay in Southern Indiana

Find the best Southern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southern Indiana
The entrance to the Kentucky Science Center with a large circular structure in the foreground.

West Main Historic District

Boasting the largest collection of cast iron façades outside New York's SoHo district, this historic area features "Museum Row" with attractions like the Louisville Slugger Museum and Muhammad Ali Center.

Find hotels in West Main Historic District

Find the Best Southern Indiana Vacation Packages

Southern Indiana Hotel Deals

Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
Fully refundableReserve now, pay when you stay
The price is NT$2,137 per night from Jul 19 to Jul 20
NT$2,137
NT$2,415 total
Jul 19 - Jul 20
includes taxes & fees
7/10 Good! (3,235 reviews)
"The stay over all was wonderful!"

Reviewed on 2026/7/12

Radisson Hotel Louisville North
Santas Lodge and Resort

Santas Lodge and Resort

2.5 out of 5
91 W CHRISTMAS BLVD Santa Claus IN
Fully refundableReserve now, pay when you stay
The price is NT$5,953 per night from Jul 15 to Jul 16
NT$5,953
NT$6,667 total
Jul 15 - Jul 16
includes taxes & fees
8/10 Very Good! (354 reviews)
"Pros: -Close to Holiday World -Close to restaurants/grocery store/gas -Had a playground outside and pool/spa -Breakfast was good and a large seating area Cons: -Room was dirty -Room was in high need of refurbishment -Linens were terrible (hard to find linens without stains or did not seem 10+ years ..."

Reviewed on 2026/7/9

Santas Lodge and Resort
Bally’s Evansville Casino & Hotel

Bally’s Evansville Casino & Hotel

3 out of 5
421 NW Riverside Drive Evansville IN
Fully refundableReserve now, pay when you stay
The price is NT$2,060 per night from Jul 26 to Jul 27
NT$2,060
NT$3,146 total
Jul 26 - Jul 27
includes taxes & fees
7.8/10 Good! (1,285 reviews)
"Room was very nice - shower was fantastic. instruction wasnt very good on how to get to our part of the hotel and park. And because we were there on a Monday- there weren’t a lot of dining options. But we would stay again."

Reviewed on 2026/7/12

Bally’s Evansville Casino & Hotel
See all 1,559 properties in Southern Indiana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Southern Indiana attractions

A water slide with a yellow and green inflatable raft carrying three people.
Photo by Indiana Office of Tourism Development
Open Photo by Indiana Office of Tourism Development

Holiday World and Splashin' Safari

9.4/10 (294 reviews)
Holiday World features themed holiday areas with thrilling coasters and water attractions. Enjoy complimentary soft drinks and sunscreen while experiencing the world's longest water coaster, Wildebeest.
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Frequently asked questions

How much does a Southern Indiana vacation package cost?
We make it simple to travel somewhere new, with Southern Indiana vacation packages starting from just . You'll have the flexibility to combine your preferred airlines, hotels and car rental. For the ultimate escape, why not add a few activities and tours to your itinerary?
How do I get a cheap travel package to Southern Indiana?
If you love bargains, combine your bookings into a Southern Indiana vacation package. Whether you're looking for flights, hotels, day tours or rental cars, you can book everything in one place. You'll have plenty of choice at your fingertips too. Expedia has over 550 airlines and 1,000,000 hotels around the globe to take your pick of. Fly with who you want, stay where you like and save a packet — now that's the ideal getaway!
Where should I stay in Southern Indiana?
Louisville is a fantastic place to explore. It draws in many travelers who come to see its top sights, like Churchill Downs and Muhammad Ali Center.
What are the top hotels in Southern Indiana?
When it comes to properties in Louisville, Galt House Hotel Trademark Collection by Wyndham and Radisson Hotel Louisville Jeffersonville are two fantastic options. If you're also spending time in Jeffersonville - Clarksville, Radisson Hotel Louisville Jeffersonville and JW Marriott Indianapolis look forward to welcoming you.
How far in advance should I book my Southern Indiana vacation?
It all depends on the airline, but you can normally browse through international airfares on Expedia up to a year in advance. While it's a good idea to book ahead of time, lucky travelers will sometimes score a cheaper seat only weeks before the date of departure.
What does an Expedia Southern Indiana travel package include?
With Expedia, you can select any combination of flights, car rentals and hotels to create your ideal Southern Indiana travel package. Once you've made your booking, you can add on all the fun stuff like sightseeing tours and activities. Remember — the more you bundle, the greater the savings!
What should I know before booking a Southern Indiana travel package?
You'll save plenty with an Expedia travel package. Combine your airfares, rental cars and hotels and land fabulous discounts. Hotels aren't your only choice, though. Book with us and select from island resorts, rural cottages and everything in between!
Can I choose my airline with a Southern Indiana Expedia vacation package?
Expedia offers access to more than 550 partner airlines globally, so you certainly can. Simply select the carrier that suits you and create the perfect Southern Indiana trip.
If I'm not able to travel, can I cancel my Southern Indiana vacation package?
Yes, you can. We understand that even the best-laid plans can go awry, so we're here to help if you have to make changes to your Southern Indiana vacation package. You may be able to amend or cancel your itinerary at no cost if you've booked in the last 24 hours. Your hotel, airline or car rental company may impose a fee if your booking was made more than 24 hours ago. Have a look at our Customer Service Portal for more information. Also, be sure to check your itinerary for the finer details on change fees.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.