The Best Hotels Closest to Maine Medical Center in Portland for 2026

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Our top choices for Maine Medical Center hotels

A multi-story building with a stone facade, large windows, and a corner entrance.

A modern living room with a large window, a sofa, a coffee table, a TV, and a brick wall.

A spacious living area with exposed brick walls, a wooden staircase, and a large window offering a view of the city.

A modern kitchen with a central island, wooden beams on the ceiling, and a dining area with a round table and chairs.

1. Evalina Hotel

Old Port, 1.7 km from Maine Medical Center

Rick

NT$9,402

NT$15,139 total

includes taxes & fees

Nov 24 - Nov 25

A spacious living room with a large window, a round coffee table, and two wooden chairs.

A hotel room with a large bed, a headboard, a nightstand, a TV mounted on the wall, and a window with a view of buildings outside.

A modern kitchen with a bar area, large windows, and a flat-screen TV.

A modern kitchen with a central island, two stools, and a dining area with a sofa and a coffee table.

2. The Docent's Collection at 178 Middle Street

Old Port, 1.7 km from Maine Medical Center

JAYASEN

NT$6,279

NT$6,844 total

includes taxes & fees

Nov 18 - Nov 19

A room with a brick wall, a window with a view of trees, a vinyl record player, and a potted plant.

A modern kitchen with a central island, bar stools, a dining table, and a built-in oven.

A modern bedroom with a large bed, two bedside tables with lamps, a large abstract painting, a brick wall, and a window with a view of trees.

A room with a round wooden table, two chairs, a potted plant, a large window, and a round mirror on the wall.

3. The Weldon Hotel

Downtown Portland, 1.4 km from Maine Medical Center

Victoria

NT$5,798

NT$8,765 total

includes taxes & fees

Nov 17 - Nov 18

A spacious living room with a large dining table, comfortable seating, and large windows offering views of the city.

A hotel room with a bed, a nightstand with a lamp, a mirror, a bathroom with a sink and a shower.

A staircase with a handrail, a wall with framed pictures, and a door with a handle.

A modern kitchen with a central island, stainless steel appliances, and wooden bar stools.

4. The Docent's Collection at 121 Middle Street

Old Port, 1.9 km from Maine Medical Center

FRANCESCA

NT$5,835

NT$6,360 total

includes taxes & fees

Nov 2 - Nov 3

A four-poster bed with a chandelier, a bedside table with books, and a view of a brick building through the windows.

A wooden deck with two wicker chairs and a small table, overlooking a brick building with ivy and a fire escape.

A spacious kitchen with a central island, wooden bar stools, and a long dining table.

A cozy room with a brick fireplace, a bench, and a table.

5. Blind Tiger Portland - Danforth Street.

West End, 1.1 km from Maine Medical Center

Mary

NT$7,955

NT$8,671 total

includes taxes & fees

Nov 8 - Nov 9

6. West End Collection at 146 Pine

West End, 0.5 km from Maine Medical Center

Stephanie

NT$6,814

NT$7,427 total

includes taxes & fees

Nov 1 - Nov 2

A well-lit living room with a fireplace, comfortable seating, and a large mirror.

A hotel room with a checkered bedspread, a large mirror above the bed, and two windows with curtains.

A staircase with a wooden handrail and a chandelier.

A red brick building with a classic facade, a front entrance with double doors, and a small porch area with potted plants.

7. Blind Tiger Portland – Carleton Street

West End, 0.4 km from Maine Medical Center

Ryan

NT$7,076

NT$7,713 total

includes taxes & fees

Nov 17 - Nov 18

A brick building with a sign reading "WAYPOINT" and outdoor seating with tables, chairs, and a fire pit.

A chef in a black uniform and white hat, holding a ladle and a bowl, with various dishes in front of him.

A hotel room with two beds, a stone-patterned wall, and a nightstand with a lamp.

A swimming pool with clear blue water, surrounded by lounge chairs and a brick wall.

8. Embassy Suites by Hilton Portland Maine

2.9 km from Maine Medical Center

Robert

NT$3,876

NT$4,289 total

includes taxes & fees

Nov 1 - Nov 2

A balcony with a table and chairs, overlooking a street with buildings and parked cars.

A hot tub area with a tiled floor, a wooden bench, a potted plant, and towels on a rack.

A restaurant with a brick fireplace, white chairs, and tables set for dining.

A bar area with a wooden bar counter, multiple liquor bottles, and a sign reading 'TRON SIDE'. There are three bar stools and a sofa in the seating area.

9. Portland Regency Hotel & Spa

Old Port, 1.8 km from Maine Medical Center

Lynn

NT$4,129

NT$4,568 total

includes taxes & fees

Nov 3 - Nov 4

A waterfront marina with boats docked, buildings with multiple windows, and a red building with a visible restaurant.

A hotel room with two beds, a desk, a TV, and a view of a body of water.

A hotel lobby with a bar area, seating arrangements, and a fireplace.

A spacious lobby with a high ceiling, large chandeliers, and a mix of seating areas including sofas and armchairs.

10. Hilton Garden Inn Portland Downtown Waterfront

Old Port, 2.1 km from Maine Medical Center

Craig R

NT$3,449

NT$3,815 total

includes taxes & fees

Nov 18 - Nov 19

An outdoor seating area with a fire feature, comfortable seating, and a view of a waterfront.

A modern interior with a fireplace, seating area, and large windows.

11. Canopy by Hilton Portland Waterfront

Old Port, 1.5 km from Maine Medical Center

Cal

NT$5,019

NT$5,553 total

includes taxes & fees

Nov 17 - Nov 18

A brick building with a white entrance and the name "THE FRANCIS" above the door.

A balcony with a round table and orange chairs, overlooking a garden with various plants and flowers.

A living room with a grey sofa set, a wooden staircase, and a potted plant.

A room with a mustard-colored sofa, two round tables, and various framed artworks on the walls.

12. The Francis

Parkside, 0.3 km from Maine Medical Center

Graig

NT$4,252

NT$5,612 total

includes taxes & fees

Nov 5 - Nov 6

A modern bar area with a counter and stools, surrounded by patterned chairs and a blue sofa.

A multi-story brick building with a flat roof, large windows, and outdoor seating areas.

A hotel room with a bed, a small table, and a window with curtains.

A wellness spa interior with a reception desk, potted plants, and wellness-related posters.

13. Longfellow Hotel

Parkside, 0.3 km from Maine Medical Center

thomas

NT$7,306

NT$9,344 total

includes taxes & fees

Nov 2 - Nov 3

A modern interior with a bar area, seating, and shelves with plants and books.

A rooftop terrace with a sofa, two chairs, and a small table, overlooking a cityscape and a body of water.

A modern living room with a large sectional sofa, a dining area with a kitchen in the background, and large windows offering a city view.

A cozy living room with a fireplace, two green armchairs, a coffee table, and a yellow ottoman.

14. The Press Hotel, Marriott Autograph Collection

Downtown Portland, 1.6 km from Maine Medical Center

Mark

NT$6,207

NT$8,302 total

includes taxes & fees

Nov 22 - Nov 23

A modern bar area with a wooden bar counter, black bar stools, and a contemporary light fixture.

A black SUV parked in front of AC Hotel Portland, a modern building with a brick facade and large windows.

A modern reception area with a central desk, seating arrangements, and large windows offering views of the cityscape.

A modern living room with a sofa, two armchairs, a glass coffee table, and a decorative wall panel.

15. AC Hotel Portland Downtown/Waterfront, ME

Downtown Portland, 2.3 km from Maine Medical Center

Kin Mong

NT$3,097

NT$3,427 total

includes taxes & fees

Nov 23 - Nov 24

A fire pit surrounded by wicker chairs in a garden setting.

A spacious living area with large windows, a staircase, and modern furniture.

A dining area with round tables and chairs, a view of the garden through large windows, and a cozy atmosphere.

A hotel room with a large bed, two bedside tables, a chair, a window with curtains, and a view of the city.

16. Portland Harbor Hotel

Old Port, 1.6 km from Maine Medical Center

Eric

NT$4,331

NT$6,035 total

includes taxes & fees

Nov 22 - Nov 23

A rooftop terrace with a modern outdoor seating area, a fire pit, and a view of the cityscape.

A modern living room with a sofa, armchairs, a coffee table, and a rug.

A modern dining area with a dark blue booth seating, wooden ceiling beams, and large windows providing natural light.

A modern bar area with a long counter, multiple stools, and a variety of bottles and glasses on shelves.

17. Cambria Hotel Portland Downtown-Old Port

Downtown Portland, 2.3 km from Maine Medical Center

Rebecca

NT$3,298

NT$4,537 total

includes taxes & fees

Nov 1 - Nov 2

A modern bar area with a bar counter, seating, and a view of the cityscape.

A modern hotel entrance with a glass facade, outdoor seating, and a well-lit lobby area.

A hotel room with two beds, a TV, a desk, and a view of the city.

A pool table with balls, a sofa, and a dining area with chairs and tables.

18. Aloft by Marriott Portland Downtown Waterfront ME

Downtown Portland, 1.4 km from Maine Medical Center

Aubrey

NT$2,843

NT$3,145 total

includes taxes & fees

Nov 22 - Nov 23

A swimming pool with lounge chairs and tables, indoor lighting, and a ceiling with ventilation.

A modern bar area with a long counter, multiple seating options, and a built-in fire feature.

A modern bar area with seating and a bar counter.

A conference room with a stage featuring a large screen displaying the word 'Float' and a banner for the University of Maine.

19. Holiday Inn Portland-By the Bay by IHG

Portland Arts District, 1.2 km from Maine Medical Center

Meredith

NT$2,836

NT$3,154 total

includes taxes & fees

Nov 23 - Nov 24

An outdoor patio area with wicker furniture, string lights, and a barbecue grill.

A bar area with stools, a counter, and a herringbone-patterned wall.

A brick building with a large entrance and a sign that reads "Residence Inn Marriott".

A swimming pool with a tiled deck, lounge chairs, and a ceiling with recessed lighting.

20. Residence Inn by Marriott Portland Downtown/Waterfront

Downtown Portland, 2.3 km from Maine Medical Center

Diane

NT$3,032

NT$3,354 total

includes taxes & fees

Nov 22 - Nov 23

View all properties

Compare popular hotels close to Maine Medical Center

Property	Property class	Guest rating
Evalina Hotel	10.0 Exceptional 16 reviews	View
The Docent's Collection at 178 Middle Street	9.8 Exceptional 85 reviews	View
The Weldon Hotel	9.8 Exceptional 127 reviews	View
The Docent's Collection at 121 Middle Street	9.6 Exceptional 422 reviews	View
Blind Tiger Portland - Danforth Street.	9.6 Exceptional 201 reviews	View

Top Maine Medical Center Hotel Reviews

Aloft by Marriott Portland Downtown Waterfront ME

10/10 Excellent

"Great location and clean rooms. The walls aren’t very thick though so you can hear a lot. The bar is a fun vibe and the bartender, Chris, was wonderful! Great service and conversation."

Holiday Inn Portland-By the Bay by IHG

10/10 Excellent

"Everything was clean and updated. All of the staff were very helpful. The breakfast was the best quality and variety I have EVER had. We did not have a chance to use the sauna or pool. I wish every hotel was this wonderful. The elevators weren’t crowded. We had an airport shuttle. Everything was positive."

Portland Regency Hotel & Spa

10/10 Excellent

"We had a great stay at the Portland regency. The staff was amazing and accommodating! The food is amazing in both restaurants on property. We will be back!"

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

8/10 Good

"Clean. Quiet. Safe. Helpful staff Breakfast"

Portland Harbor Hotel

10/10 Excellent

"A wonderful stay while in Ashbury, NJ! The view from our oceanside window was beautiful. Well worth the extra $ to get the ocean view large window. Friendly staff, comfy room. Hope to return some day. What a fun town, too!"

Cambria Hotel Portland Downtown-Old Port

8/10 Good

"The room was beautiful, the whole building was cleaned extremely well. The amenities were beautiful, but the kitchen was out of many of the breakfast options, so we didn't want to test their dinner options and ate elsewhere. The location was absolutely perfect!! It was very walkable. If you plan on staying in the Portland area for your trip, I would skip over renting a car. It's a $40 daily valet and there are no alternative parking areas that we could find. It would have been cheaper to just get a ride from the airport and walk everywhere else. Overall, I was very pleased with my stay and would recommend it going forward."

Longfellow Hotel

8/10 Good

"Very lovely boutique hotel in downtown Portland, Maine. Small rooms, and there is no storage, so you have to live out of your suitcase for a couple of days. And there is no table and only one chair so that’s a negative, if you want to work in your room or have room service, there’s nowhere to sit and eat. The walk-in range shower is great, bathroom is lovely, but the water pressure in the bathroom sink is terrible. But overall, a lovely hotel, if I stayed again, probably just for one night. They do have lovely amenities, the bar is great, well stocked in a variety of good cocktails. The breakfast that we had was really good and they have a lovely free limo service to take you to and from your various visit around Portland"

Hilton Garden Inn Portland Downtown Waterfront

10/10 Excellent

"Great location, very scenic. Walking distance to everywhere in downtown Portland!"

Hampton Inn Portland Downtown - Waterfront

10/10 Excellent

"Nice little property only a ten minute ride to the beach"

Frequently asked questions

What's the area like around Maine Medical Center?

Maine Medical Center is located in a welcoming area of Portland known for its beautiful ocean views and sporting events. If you're looking for a convenient place to stay, check out the 195 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Maine Medical Center?

Adjacent to Maine Medical Center, Inn at St John Portland In-Town is one of the top choices for your stay based on our traveler data, and this B&B offers free breakfast and free parking. Other good options within a short distance include Clarion Hotel Portland Airport ME and La Quinta Inn & Suites by Wyndham Portland DT/Maine Med.

How many hotels are there close to Maine Medical Center?

Expedia has 195 hotels and other accommodations within a mile from Maine Medical Center.

If I need to cancel the hotel reservation for my stay near Maine Medical Center, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view top deals close to Maine Medical Center.

Where can I learn more about changing or cancelling my trip in the area near Maine Medical Center?

For additional details about changing or cancelling your stay near Maine Medical Center, click here.

What can I see and do near Maine Medical Center?

Portland Museum of Art, Maine Narrow Gauge Railroad, and International Cryptozoology Museum feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like State Theatre, Victoria Mansion, and Portland Head Light. You can watch performances at Merrill Auditorium, Port City Music Hall, and Portland Stage if you're interested in local theater.

Find hotels near Maine Medical Center, Portland from NT$3,145

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Maine Medical Center hotels

1. Evalina Hotel

2. The Docent's Collection at 178 Middle Street

3. The Weldon Hotel

4. The Docent's Collection at 121 Middle Street

5. Blind Tiger Portland - Danforth Street.

6. West End Collection at 146 Pine

7. Blind Tiger Portland – Carleton Street

8. Embassy Suites by Hilton Portland Maine

9. Portland Regency Hotel & Spa

10. Hilton Garden Inn Portland Downtown Waterfront

11. Canopy by Hilton Portland Waterfront

12. The Francis

13. Longfellow Hotel

14. The Press Hotel, Marriott Autograph Collection

15. AC Hotel Portland Downtown/Waterfront, ME

16. Portland Harbor Hotel

17. Cambria Hotel Portland Downtown-Old Port

18. Aloft by Marriott Portland Downtown Waterfront ME

19. Holiday Inn Portland-By the Bay by IHG

20. Residence Inn by Marriott Portland Downtown/Waterfront

Compare popular hotels close to Maine Medical Center

Top Maine Medical Center Hotel Reviews

Aloft by Marriott Portland Downtown Waterfront ME

Holiday Inn Portland-By the Bay by IHG

Portland Regency Hotel & Spa

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

Portland Harbor Hotel

Cambria Hotel Portland Downtown-Old Port

Longfellow Hotel

Hilton Garden Inn Portland Downtown Waterfront

Hampton Inn Portland Downtown - Waterfront

Frequently asked questions

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