The Best Hotels Closest to Maine Medical Center in Portland for 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Maine Medical Center hotels

A spacious living room with a large window, a round coffee table, and two wooden chairs.

A hotel room with a large bed, a headboard, a nightstand, a TV mounted on the wall, and a window with a view of buildings outside.

A modern kitchen with a bar area, large windows, and a flat-screen TV.

A modern kitchen with white cabinetry, a marble backsplash, two wooden stools, and a potted plant.

1. The Docent's Collection at 178 Middle Street

Old Port, 1.7 km from Maine Medical Center

JAYASEN

NT$6,269

NT$6,833 total

includes taxes & fees

Nov 10 - Nov 11

A modern kitchen with a central island, bar stools, a dining table, and a built-in oven.

A modern bedroom with a large bed, two bedside tables with lamps, a large abstract painting, a brick wall, and a window with a view of trees.

A room with a round wooden table, two chairs, a potted plant, a large window, and a round mirror on the wall.

2. The Weldon Hotel

Downtown Portland, 1.4 km from Maine Medical Center

Victoria

NT$5,943

NT$8,923 total

includes taxes & fees

Nov 16 - Nov 17

A historic building with multiple storefronts, including a visible sign for 'TOPPLE' and 'BLISS.'

A spacious living room with a large dining table, comfortable seating, and large windows offering views of the city.

A modern living room with a sofa, coffee table, and chairs. There is a kitchen area with cabinets and a refrigerator.

A hotel room with a bed, a nightstand with a lamp, a mirror, a bathroom with a sink and a shower.

3. The Docent's Collection at 121 Middle Street

Old Port, 1.9 km from Maine Medical Center

FRANCESCA

NT$5,664

NT$6,174 total

includes taxes & fees

Oct 25 - Oct 26

A four-poster bed with a chandelier, a bedside table with books, and a view of a brick building through the windows.

A wooden deck with two wicker chairs and a small table, overlooking a brick building with ivy and a fire escape.

A spacious kitchen with a central island, wooden bar stools, and a long dining table.

A cozy room with a brick fireplace, a bench, and a table.

4. Blind Tiger Portland - Danforth Street.

West End, 1.1 km from Maine Medical Center

Mary

NT$7,541

NT$8,219 total

includes taxes & fees

Nov 19 - Nov 20

A well-lit living room with a fireplace, comfortable seating, and a large mirror.

A room with a wooden chair, a cushioned bench, a small table with books and vases, and a potted plant.

A red brick building with a classic facade, a front entrance with double doors, and a small porch area with potted plants.

A hotel room with a checkered bedspread, a large mirror above the bed, and two windows with curtains.

5. Blind Tiger Portland – Carleton Street

West End, 0.4 km from Maine Medical Center

Samuel

NT$7,228

NT$7,878 total

includes taxes & fees

Nov 17 - Nov 18

A brick building with a sign reading "WAYPOINT" and outdoor seating with tables, chairs, and a fire pit.

A hotel room with two beds, a stone-patterned wall, and a nightstand with a lamp.

A chef in a black uniform and white hat, holding a ladle and a bowl, with various dishes in front of him.

A spacious lobby with multiple seating areas, a fireplace, and large windows.

6. Embassy Suites by Hilton Portland Maine

2.9 km from Maine Medical Center

Robert

NT$3,876

NT$4,289 total

includes taxes & fees

Nov 2 - Nov 3

A brick building with a red awning labeled "Chateau Riverside."

A restaurant with a brick fireplace, white chairs, and tables set for dining.

A balcony with a table and chairs, overlooking a street with buildings and parked cars.

A hot tub area with a tiled floor, a wooden bench, a potted plant, and towels on a rack.

7. Portland Regency Hotel & Spa

Old Port, 1.8 km from Maine Medical Center

Lynn

NT$4,122

NT$4,561 total

includes taxes & fees

Nov 3 - Nov 4

A modern living room with a large sectional sofa, a dining area with a kitchen in the background, and large windows offering a city view.

A rooftop terrace with a sofa, two chairs, and a small table, overlooking a cityscape and a body of water.

A cozy living room with a fireplace, two green armchairs, a coffee table, and a yellow ottoman.

A modern interior with a bar area, seating, and shelves with plants and books.

8. The Press Hotel, Marriott Autograph Collection

Downtown Portland, 1.6 km from Maine Medical Center

Mark

NT$6,207

NT$8,302 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor seating area with a fire feature, comfortable seating, and a view of a waterfront.

A modern kitchen with a central island, pendant lighting, and built-in appliances.

A modern living room with a fireplace, sofas, a coffee table, and a bookshelf.

A modern interior with a fireplace, seating area, and large windows.

9. Canopy by Hilton Portland Waterfront

Old Port, 1.5 km from Maine Medical Center

Cal

NT$5,031

NT$5,566 total

includes taxes & fees

Nov 23 - Nov 24

A rooftop terrace with a modern outdoor seating area, a fire pit, and a view of the cityscape.

A modern lobby with a geometric wall design, seating area, and a large abstract artwork.

A modern bar area with a long counter, multiple stools, and a variety of bottles and glasses on shelves.

A modern dining area with a dark blue booth seating, wooden ceiling beams, and large windows providing natural light.

10. Cambria Hotel Portland Downtown-Old Port

Downtown Portland, 2.3 km from Maine Medical Center

susan

NT$3,298

NT$4,537 total

includes taxes & fees

Nov 1 - Nov 2

A modern living room with a sofa, two armchairs, a glass coffee table, and a decorative wall panel.

A black SUV parked in front of AC Hotel Portland, a modern building with a brick facade and large windows.

A modern bar area with a wooden bar counter, black bar stools, and a contemporary light fixture.

A modern reception area with a central desk, seating arrangements, and large windows offering views of the cityscape.

11. AC Hotel Portland Downtown/Waterfront, ME

Downtown Portland, 2.3 km from Maine Medical Center

Kin Mong

NT$3,228

NT$3,571 total

includes taxes & fees

Nov 22 - Nov 23

A hotel entrance with a glass door, a column, and potted plants.

A modern bar area with seating and a bar counter.

A conference room with a stage featuring a large screen displaying the word 'Float' and a banner for the University of Maine.

A swimming pool with lounge chairs and tables, surrounded by a well-lit indoor area with a view of the outside.

12. Holiday Inn Portland-By the Bay by IHG

Portland Arts District, 1.2 km from Maine Medical Center

Meredith

NT$2,836

NT$3,154 total

includes taxes & fees

Nov 22 - Nov 23

A grand piano in a spacious room with large windows, leather chairs, and a small table.

A bar area with a long counter, multiple stools, and a variety of bottles and glasses.

A banquet hall with round tables, white tablecloths, and wooden chairs.

The exterior of the Westin hotel with a prominent entrance and two bicycles parked in front.

13. The Westin Portland Harborview

Downtown Portland, 0.9 km from Maine Medical Center

Samuel

NT$3,521

NT$3,896 total

includes taxes & fees

Nov 18 - Nov 19

A two-story house with a porch and a sign reading "Fleetwork House."

A bathroom with wooden cabinetry, a sink, a mirror, and framed artwork on the wall.

A covered outdoor patio with a grill, seating area, and potted plants.

A dining table set with a fruit bowl, cutlery, and decorative elements like a pumpkin and autumn leaves.

14. Fleetwood House Bed & Breakfast

Rosemont, 2.7 km from Maine Medical Center

Karen

NT$7,454

NT$8,450 total

includes taxes & fees

Oct 27 - Oct 28

A pool table with balls, a sofa, and a dining area with chairs and tables.

A hotel room with two beds, a TV, a desk, and a view of the city.

A modern bar area with a bar counter, seating, and a view of the cityscape.

A modern hotel entrance with a glass facade, outdoor seating, and a well-lit lobby area.

15. Aloft by Marriott Portland Downtown Waterfront ME

Downtown Portland, 1.4 km from Maine Medical Center

Aubrey

NT$2,843

NT$3,145 total

includes taxes & fees

Nov 22 - Nov 23

A historic building with classical architecture, featuring a prominent tower and ornate columns.

A modern hotel with a dark facade, multiple windows, and a visible sign for 'Hyatt Place'.

A balcony with wooden flooring, striped cushioned chairs, and a glass railing overlooking a cityscape at night.

A bar area with a polished granite countertop, a variety of liquor bottles, a fruit bowl, and blue upholstered bar stools.

16. Hyatt Place Portland Downtown - Old Port Square

Old Port, 1.6 km from Maine Medical Center

Kelly

NT$4,199

NT$4,646 total

includes taxes & fees

Nov 3 - Nov 4

A multi-story hotel with a prominent entrance, large windows, and a well-lit facade.

A modern lounge area with a fireplace, seating, and a large window.

A living room with a sofa, a small table, and a window with a view of a bridge and buildings.

A reception desk with a "Welcome to the Lobster State" sign, a "Hilton Honors" sign, and a digital screen.

17. Hampton Inn Portland Downtown - Waterfront

Downtown Portland, 2 km from Maine Medical Center

Heather

NT$3,176

NT$3,514 total

includes taxes & fees

Nov 18 - Nov 19

A multi-story building with a stone facade, multiple windows, and awnings.

A breakfast bar with various food items, a clock, and a mirror.

A sign for "The Inn at St. John" with a pineapple emblem.

A hotel lobby with a reception desk, several armchairs, a patterned carpet, and a red wall with framed pictures.

18. Inn at St John Portland In-Town

Valley Street, 0.3 km from Maine Medical Center

Shad

NT$2,712

NT$2,956 total

includes taxes & fees

Oct 25 - Oct 26

A modern building with a sign reading 'Residence Inn' above the entrance.

A gym with treadmills, a weight bench, and exercise balls.

A modern dining area with round tables and chairs, pendant lighting, and artwork on the walls.

A hotel room with two beds, a desk, a chair, a TV, and large windows with a view of a body of water.

19. Residence Inn by Marriott Portland Thompson's Point

1.4 km from Maine Medical Center

Yadira

NT$3,945

NT$4,364 total

includes taxes & fees

Nov 22 - Nov 23

A modern hotel lobby with a reception desk, a coffee station, and a tiled wall.

A modern living room with a fireplace, comfortable seating, and a flat-screen TV.

A hotel room with a large bed, a desk with a flat-screen TV, a bathroom with a sink and mirror, and a door leading to another room.

20. La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

0.6 km from Maine Medical Center

Paula

NT$2,900

NT$3,209 total

includes taxes & fees

Nov 3 - Nov 4

View all properties

Compare popular hotels close to Maine Medical Center

Property	Property class	Guest rating
The Docent's Collection at 178 Middle Street	9.8 Exceptional 84 reviews	View
The Weldon Hotel	9.8 Exceptional 127 reviews	View
The Docent's Collection at 121 Middle Street	9.6 Exceptional 421 reviews	View
Blind Tiger Portland - Danforth Street.	9.6 Exceptional 200 reviews	View
Blind Tiger Portland – Carleton Street	9.6 Exceptional 137 reviews	View

Top Maine Medical Center Hotel Reviews

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

8/10 Good

"So far so good"

Clarion Hotel Portland Airport ME

10/10 Excellent

"Our first time to the area. Clean room, great amenities"

Aloft by Marriott Portland Downtown Waterfront ME

8/10 Good

"Room a bit too minimal and open and therefore noisy and didn’t feel private, especially with an open bathroom area. Area is great, walkable. Staff is amazing. Love the shuttle availability."

Blind Tiger Portland – Carleton Street

10/10 Excellent

"Quick responses by staff! Comfortable bed! Gorgeous amenities! Loved the location was right down from Tandem Coffee!"

Cambria Hotel Portland Downtown-Old Port

10/10 Excellent

"Beautiful room with a great view!!"

Canopy by Hilton Portland Waterfront

10/10 Excellent

"Great stay & great location!"

Courtyard Portland Downtown/Waterfront

10/10 Excellent

"Great waterfront location in Portland. Convenient to airport, shopping and restaurants."

West End Collection at 146 Pine

10/10 Excellent

"This was a super cute boutique inn and the location was ideal. The staff was super friendly!"

Frequently asked questions

What's the area like around Maine Medical Center?

Maine Medical Center is located in a welcoming area of Portland known for its beautiful ocean views and sporting events. If you're looking for a convenient place to stay, check out the 195 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Maine Medical Center?

Adjacent to Maine Medical Center, Inn at St John Portland In-Town is one of the top choices for your stay based on our traveler data, and this B&B offers free breakfast and free parking. Other good options within a short distance include Clarion Hotel Portland Airport ME and La Quinta Inn & Suites by Wyndham Portland DT/Maine Med.

How many hotels are there close to Maine Medical Center?

Expedia has 195 hotels and other accommodations within a mile from Maine Medical Center.

If I need to cancel the hotel reservation for my stay near Maine Medical Center, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view top deals close to Maine Medical Center.

Where can I learn more about changing or cancelling my trip in the area near Maine Medical Center?

For additional details about changing or cancelling your stay near Maine Medical Center, click here.

What can I see and do near Maine Medical Center?

Portland Museum of Art, Maine Narrow Gauge Railroad, and International Cryptozoology Museum feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like State Theatre, Victoria Mansion, and Portland Head Light. You can watch performances at Merrill Auditorium, Port City Music Hall, and Portland Stage if you're interested in local theater.

Find hotels near Maine Medical Center, Portland from NT$2,956

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Maine Medical Center hotels

1. The Docent's Collection at 178 Middle Street

2. The Weldon Hotel

3. The Docent's Collection at 121 Middle Street

4. Blind Tiger Portland - Danforth Street.

5. Blind Tiger Portland – Carleton Street

6. Embassy Suites by Hilton Portland Maine

7. Portland Regency Hotel & Spa

8. The Press Hotel, Marriott Autograph Collection

9. Canopy by Hilton Portland Waterfront

10. Cambria Hotel Portland Downtown-Old Port

11. AC Hotel Portland Downtown/Waterfront, ME

12. Holiday Inn Portland-By the Bay by IHG

13. The Westin Portland Harborview

14. Fleetwood House Bed & Breakfast

15. Aloft by Marriott Portland Downtown Waterfront ME

16. Hyatt Place Portland Downtown - Old Port Square

17. Hampton Inn Portland Downtown - Waterfront

18. Inn at St John Portland In-Town

19. Residence Inn by Marriott Portland Thompson's Point

20. La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

Compare popular hotels close to Maine Medical Center

Top Maine Medical Center Hotel Reviews

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

Clarion Hotel Portland Airport ME

Aloft by Marriott Portland Downtown Waterfront ME

Blind Tiger Portland – Carleton Street

Cambria Hotel Portland Downtown-Old Port

Canopy by Hilton Portland Waterfront

Courtyard Portland Downtown/Waterfront

West End Collection at 146 Pine

Frequently asked questions

Explore a world of travel with Expedia