The Best Hotels Closest to Maine Medical Center in Portland for 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Maine Medical Center hotels

A multi-story building with a stone facade, large windows, and a corner entrance.

A spacious living area with exposed brick walls, a wooden staircase, and a large window offering a view of the city.

A modern living room with a large window, a sofa, a coffee table, a TV, and a brick wall.

A modern living room with a large window, a TV, a sofa, a coffee table, and a dining area with a brick wall.

1. Evalina Hotel

Old Port, 1.7 km from Maine Medical Center

Eric

NT$19,790

NT$26,304 total

includes taxes & fees

Sep 13 - Sep 14

A modern kitchen with a central island, bar stools, a dining table, and a built-in oven.

A room with a round wooden table, two chairs, a potted plant, a large window, and a round mirror on the wall.

A multi-story brick building with a modern design, featuring large windows and a flat roof.

2. The Weldon Hotel

Downtown Portland, 1.4 km from Maine Medical Center

Victoria

NT$12,397

NT$15,876 total

includes taxes & fees

Sep 21 - Sep 22

3. West End Collection at 146 Pine

West End, 0.5 km from Maine Medical Center

Svetlana

NT$8,100

NT$8,829 total

includes taxes & fees

Sep 21 - Sep 22

A modern bar area with a counter and stools, surrounded by patterned chairs and a blue sofa.

A wellness spa interior with a reception desk, potted plants, and wellness-related posters.

A hotel room with a bed, a small table, and a window with curtains.

A multi-story brick building with a flat roof, large windows, and outdoor seating areas.

4. Longfellow Hotel

Parkside, 0.3 km from Maine Medical Center

Alexis

NT$12,168

NT$14,682 total

includes taxes & fees

Sep 27 - Sep 28

A spacious living room with a large window, a round coffee table, and two wooden chairs.

A modern kitchen with a central island, two stools, and a dining area with a sofa and a coffee table.

A hotel room with a large bed, a headboard, a nightstand, a TV mounted on the wall, and a window with a view of buildings outside.

A modern kitchen with white cabinetry, a marble backsplash, two wooden stools, and a potted plant.

5. The Docent's Collection at 178 Middle Street

Old Port, 1.7 km from Maine Medical Center

Susan

NT$8,243

NT$8,985 total

includes taxes & fees

Sep 10 - Sep 11

A spacious living room with a large dining table, comfortable seating, and large windows offering views of the city.

A staircase with a handrail, a wall with framed pictures, and a door with a handle.

A modern living room with a sofa, coffee table, and chairs. There is a kitchen area with cabinets and a refrigerator.

A modern kitchen with a central island, stainless steel appliances, and wooden bar stools.

6. The Docent's Collection at 121 Middle Street

Old Port, 1.9 km from Maine Medical Center

Christopher

NT$8,252

NT$8,995 total

includes taxes & fees

Sep 10 - Sep 11

A well-lit living room with a fireplace, comfortable seating, and a large mirror.

A red brick building with a classic facade, a front entrance with double doors, and a small porch area with potted plants.

A hotel room with a checkered bedspread, a large mirror above the bed, and two windows with curtains.

A staircase with a wooden handrail and a chandelier.

7. Blind Tiger Portland – Carleton Street

West End, 0.4 km from Maine Medical Center

Adriana Cecilia

NT$10,273

NT$11,198 total

includes taxes & fees

Sep 29 - Sep 30

A four-poster bed with a chandelier, a bedside table with books, and a view of a brick building through the windows.

A cozy room with a brick fireplace, a bench, and a table.

A living room with a fireplace, a sofa, a coffee table, and a bookshelf.

A spacious kitchen with a central island, wooden bar stools, and a long dining table.

8. Blind Tiger Portland - Danforth Street.

West End, 1.1 km from Maine Medical Center

Lawrence

NT$10,477

NT$11,420 total

includes taxes & fees

Sep 27 - Sep 28

A balcony with a table and chairs, overlooking a street with buildings and parked cars.

A hot tub area with a tiled floor, a wooden bench, a potted plant, and towels on a rack.

A restaurant with a brick fireplace, white chairs, and tables set for dining.

A brick building with a red awning labeled "Chateau Riverside."

9. Portland Regency Hotel & Spa

Old Port, 1.8 km from Maine Medical Center

Arlene

NT$10,700

NT$11,838 total

includes taxes & fees

Sep 20 - Sep 21

A brick building with a sign reading "WAYPOINT" and outdoor seating with tables, chairs, and a fire pit.

A hotel room with two beds, a stone-patterned wall, and a nightstand with a lamp.

A chef in a black uniform and white hat, holding a ladle and a bowl, with various dishes in front of him.

A swimming pool with clear blue water, surrounded by lounge chairs and a brick wall.

10. Embassy Suites by Hilton Portland Maine

2.9 km from Maine Medical Center

Kelly

NT$6,551

NT$7,248 total

includes taxes & fees

Sep 13 - Sep 14

A waterfront marina with boats docked, buildings with multiple windows, and a red building with a visible restaurant.

A hotel room with two beds, a desk, a TV, and a view of a body of water.

A hotel lobby with a bar area, seating arrangements, and a fireplace.

A large indoor swimming pool with clear water, tiled flooring, and a seating area with chairs and a plant.

11. Hilton Garden Inn Portland Downtown Waterfront

Old Port, 2.1 km from Maine Medical Center

Jenna

NT$9,823

NT$10,868 total

includes taxes & fees

Sep 27 - Sep 28

An outdoor seating area with a fire feature, comfortable seating, and a view of the cityscape.

A modern bar with a long counter, multiple bar stools, and a large window offering a view of the cityscape.

A modern living room with a fireplace, bookshelves, and comfortable seating.

A modern interior with a fireplace, seating area, and large windows.

12. Canopy by Hilton Portland Waterfront

Old Port, 1.5 km from Maine Medical Center

john

NT$16,376

NT$18,118 total

includes taxes & fees

Sep 20 - Sep 21

A brick building with a grand entrance labeled "THE FRANCIS."

A living room with a grey sofa set, a wooden staircase, and a potted plant.

A room with a mustard-colored sofa, two round tables, and various framed artworks on the walls.

A balcony with a round table and orange chairs, overlooking a garden with various plants and flowers.

13. The Francis

Parkside, 0.3 km from Maine Medical Center

Jessica

NT$10,156

NT$12,015 total

includes taxes & fees

Sep 20 - Sep 21

A modern interior with a bar area, seating, and shelves with plants and books.

A rooftop terrace with a sofa, two chairs, and a small table, overlooking a cityscape and a body of water.

A modern living room with a large sectional sofa, a dining area with a kitchen in the background, and large windows offering a city view.

A cozy living room with a fireplace, two green armchairs, a coffee table, and a yellow ottoman.

14. The Press Hotel, Marriott Autograph Collection

Downtown Portland, 1.6 km from Maine Medical Center

Elizabeth

NT$14,579

NT$16,131 total

includes taxes & fees

Sep 27 - Sep 28

A modern bar area with a wooden bar counter, black bar stools, and a contemporary light fixture.

A modern reception area with a central desk, seating arrangements, and large windows offering views of the cityscape.

A hotel room with a large bed, a sofa, a small table, and a bench. There is a window with a view of the water.

A modern living room with a sofa, two armchairs, a glass coffee table, and a decorative wall panel.

15. AC Hotel Portland Downtown/Waterfront, ME

Downtown Portland, 2.3 km from Maine Medical Center

Nicole Emily Elizabeth

NT$9,360

NT$10,356 total

includes taxes & fees

Sep 27 - Sep 28

A fire pit surrounded by wicker chairs in a garden setting.

A spacious living area with large windows, a staircase, and modern furniture.

A living room with a fireplace, seating area, and a large window.

A hotel room with a large bed, two bedside tables, a chair, a window with curtains, and a view of the city.

16. Portland Harbor Hotel

Old Port, 1.6 km from Maine Medical Center

Brandon

NT$10,963

NT$13,333 total

includes taxes & fees

Sep 14 - Sep 15

A rooftop terrace with a modern outdoor seating area, a fire pit, and a view of the cityscape.

A modern lobby with a geometric wall design, seating area, and a large abstract artwork.

A modern dining area with a dark blue booth seating, wooden ceiling beams, and large windows providing natural light.

A modern living room with a sofa, armchairs, a coffee table, and a rug.

17. Cambria Hotel Portland Downtown-Old Port

Downtown Portland, 2.3 km from Maine Medical Center

susan

NT$9,134

NT$10,966 total

includes taxes & fees

Sep 20 - Sep 21

A modern bar area with a long counter, multiple seating options, and a built-in fire feature.

A conference room with a large screen displaying 'AFloat' and 'Holiday Inn by the bay'.

A swimming pool with lounge chairs and tables, surrounded by a well-lit indoor area with a view of the outside.

A Holiday Inn hotel with a modern design, featuring a large entrance canopy and multiple floors.

18. Holiday Inn Portland-By the Bay by IHG

Portland Arts District, 1.2 km from Maine Medical Center

Zoe

NT$7,824

NT$8,657 total

includes taxes & fees

Sep 20 - Sep 21

A modern bar area with a bar counter, seating, and a view of the cityscape.

A hotel room with two beds, a TV, a desk, and a view of the city.

A modern living room with a grey sofa, a yellow armchair, and a red armchair. There are two floor lamps, a flat-screen TV, and patterned wallpaper.

A modern hotel entrance with a glass facade, outdoor seating, and a well-lit lobby area.

19. Aloft by Marriott Portland Downtown Waterfront ME

Downtown Portland, 1.4 km from Maine Medical Center

Raysa

NT$7,348

NT$8,130 total

includes taxes & fees

Sep 20 - Sep 21

The exterior of a Courtyard by Marriott hotel with a glass entrance, outdoor seating area, and a stone facade.

A restaurant with booths and tables, brick walls, and pendant lighting.

A modern hotel lobby with a reception desk, a seating area, and a large wall mural.

A modern bar area with leather seating, a bar counter, and a menu board.

20. Courtyard Portland Downtown/Waterfront

Old Port, 1.5 km from Maine Medical Center

SCOTT

NT$10,153

NT$11,233 total

includes taxes & fees

Sep 13 - Sep 14

View all properties

Compare popular hotels close to Maine Medical Center

Property	Property class	Guest rating
Evalina Hotel	10.0 Exceptional 11 reviews	View
The Weldon Hotel	9.8 Exceptional 117 reviews	View
West End Collection at 146 Pine	9.6 Exceptional 97 reviews	View
Longfellow Hotel	9.6 Exceptional 187 reviews	View
The Docent's Collection at 178 Middle Street	9.6 Exceptional 62 reviews	View

Top Maine Medical Center Hotel Reviews

Aloft by Marriott Portland Downtown Waterfront ME

8/10 Good

"We were a party of 4 and stayed for 2 nights and only had 3 sets of towels on the first night so Let it pass . Repeatedly ask maintenance to give us 4 but still when they tried to clean the room , still gave us 3 sets and never changed the sheets ."

Hilton Garden Inn Portland Downtown Waterfront

10/10 Excellent

"we enjoyed our stay and would come again"

Inn at St John Portland In-Town

10/10 Excellent

"A"

Holiday Inn Portland-By the Bay by IHG

10/10 Excellent

"This is my 3rd time staying here. Always a great experience!"

The Westin Portland Harborview

10/10 Excellent

"Great location spacious clean rooms! Mattress were showing there age a bit but the hotel iitself was very well maintained and the staff is great!!"

Portland Harbor Hotel

10/10 Excellent

"Perfect location, clean and friendly! Would definitely stay here again!"

Moxy Portland Thompson's Point

10/10 Excellent

"Perfect location if you’re going to an event at thompson’s Point while in Portland."

Hyatt Place Portland Downtown - Old Port Square

10/10 Excellent

"Great Staff. Good Breakfast. We will return."

Portland Regency Hotel & Spa

8/10 Good

"The rooms are feeling their age but otherwise nice enough. The doors fully seal they are open at the bottom like residential doors which lets all sound and smoke in from when other neighbors smoke despite it being a non-smoking hotel. The valet staff earns special props they were friendly and incredibly helpful. Overall it’s decent just don’t know if the amount we paid was worth what we spent."

Frequently asked questions

What's the area like around Maine Medical Center?

Maine Medical Center is located in a welcoming area of Portland known for its beautiful ocean views and sporting events. If you're looking for a convenient place to stay, check out the 195 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Maine Medical Center?

Adjacent to Maine Medical Center, Inn at St John Portland In-Town is one of the top choices for your stay based on our traveler data, and this B&B offers free breakfast and free parking. Other good options within a short distance include La Quinta Inn & Suites by Wyndham Portland DT/Maine Med and Clarion Hotel Portland Airport ME.

How many hotels are there close to Maine Medical Center?

Expedia has 195 hotels and other accommodations within a mile from Maine Medical Center.

If I need to cancel the hotel reservation for my stay near Maine Medical Center, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view top deals close to Maine Medical Center.

Where can I learn more about changing or cancelling my trip in the area near Maine Medical Center?

For additional details about changing or cancelling your stay near Maine Medical Center, click here.

What can I see and do near Maine Medical Center?

Portland Museum of Art, Maine Narrow Gauge Railroad, and Fifth Maine Museum feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like State Theatre, Victoria Mansion, and Portland Head Light. You can watch performances at Merrill Auditorium, Portland Stage, and Port City Music Hall if you're interested in local theater.

Find hotels near Maine Medical Center, Portland from NT$7,248

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Maine Medical Center hotels

1. Evalina Hotel

2. The Weldon Hotel

3. West End Collection at 146 Pine

4. Longfellow Hotel

5. The Docent's Collection at 178 Middle Street

6. The Docent's Collection at 121 Middle Street

7. Blind Tiger Portland – Carleton Street

8. Blind Tiger Portland - Danforth Street.

9. Portland Regency Hotel & Spa

10. Embassy Suites by Hilton Portland Maine

11. Hilton Garden Inn Portland Downtown Waterfront

12. Canopy by Hilton Portland Waterfront

13. The Francis

14. The Press Hotel, Marriott Autograph Collection

15. AC Hotel Portland Downtown/Waterfront, ME

16. Portland Harbor Hotel

17. Cambria Hotel Portland Downtown-Old Port

18. Holiday Inn Portland-By the Bay by IHG

19. Aloft by Marriott Portland Downtown Waterfront ME

20. Courtyard Portland Downtown/Waterfront

Compare popular hotels close to Maine Medical Center

Top Maine Medical Center Hotel Reviews

Aloft by Marriott Portland Downtown Waterfront ME

Hilton Garden Inn Portland Downtown Waterfront

Inn at St John Portland In-Town

Holiday Inn Portland-By the Bay by IHG

The Westin Portland Harborview

Portland Harbor Hotel

Moxy Portland Thompson's Point

Hyatt Place Portland Downtown - Old Port Square

Portland Regency Hotel & Spa

Frequently asked questions

Explore a world of travel with Expedia