The Best Hotels Closest to Maine Medical Center in Portland for 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Maine Medical Center hotels

A multi-story building with a stone facade, large windows, and a corner entrance.

A spacious living area with exposed brick walls, a wooden staircase, and a large window offering a view of the city.

A modern living room with a large window, a TV, a sofa, a coffee table, and a dining area with a brick wall.

A modern living room with a large window, a sofa, a coffee table, a TV, and a brick wall.

1. Evalina Hotel

Old Port, 1.7 km from Maine Medical Center

Eric

NT$20,164

NT$26,745 total

includes taxes & fees

Sep 20 - Sep 21

A modern kitchen with a central island, bar stools, a dining table, and a built-in oven.

A multi-story brick building with a modern design, featuring large windows and a flat roof.

A modern bedroom with a large bed, two bedside tables with lamps, a large abstract painting, a brick wall, and a window with a view of trees.

2. The Weldon Hotel

Downtown Portland, 1.4 km from Maine Medical Center

Victoria

NT$12,050

NT$15,508 total

includes taxes & fees

Sep 22 - Sep 23

A well-lit living room with a fireplace, comfortable seating, and a large mirror.

A room with a wooden chair, a cushioned bench, a small table with books and vases, and a potted plant.

A staircase with a wooden handrail and a chandelier.

A hotel room with a checkered bedspread, a large mirror above the bed, and two windows with curtains.

3. Blind Tiger Portland – Carleton Street

West End, 0.4 km from Maine Medical Center

Adriana Cecilia

NT$10,398

NT$11,334 total

includes taxes & fees

Sep 29 - Sep 30

A spacious living room with a large window, a round coffee table, and two wooden chairs.

A modern kitchen with a central island, two stools, and a dining area with a sofa and a coffee table.

A modern kitchen with white cabinetry, a marble backsplash, two wooden stools, and a potted plant.

A hotel room with a large bed, a headboard, a nightstand, a TV mounted on the wall, and a window with a view of buildings outside.

4. The Docent's Collection at 178 Middle Street

Old Port, 1.7 km from Maine Medical Center

Susan

NT$8,311

NT$9,059 total

includes taxes & fees

Sep 27 - Sep 28

A modern bar area with a counter and stools, surrounded by patterned chairs and a blue sofa.

A hotel room with a bed, a small table, and a window with curtains.

A wellness spa interior with a reception desk, potted plants, and wellness-related posters.

5. Longfellow Hotel

Parkside, 0.3 km from Maine Medical Center

James

NT$12,218

NT$14,742 total

includes taxes & fees

Sep 27 - Sep 28

A spacious living room with a large dining table, comfortable seating, and large windows offering views of the city.

A modern living room with a sofa, coffee table, and chairs. There is a kitchen area with cabinets and a refrigerator.

A staircase with a handrail, a wall with framed pictures, and a door with a handle.

A hotel room with a bed, a nightstand with a lamp, a mirror, a bathroom with a sink and a shower.

6. The Docent's Collection at 121 Middle Street

Old Port, 1.9 km from Maine Medical Center

Christopher

NT$9,196

NT$10,024 total

includes taxes & fees

Sep 27 - Sep 28

A four-poster bed with a chandelier, a bedside table with books, and a view of a brick building through the windows.

A wooden deck with two wicker chairs and a small table, overlooking a brick building with ivy and a fire escape.

A spacious kitchen with a central island, wooden bar stools, and a long dining table.

A cozy room with a brick fireplace, a bench, and a table.

7. Blind Tiger Portland - Danforth Street.

West End, 1.1 km from Maine Medical Center

Lawrence

NT$17,487

NT$19,060 total

includes taxes & fees

Sep 30 - Oct 1

A brick building with a sign reading "WAYPOINT" and outdoor seating with tables, chairs, and a fire pit.

A spacious lobby with multiple seating areas, a fireplace, and large windows.

A chef in a black uniform and white hat, holding a ladle and a bowl, with various dishes in front of him.

A hotel room with two beds, a stone-patterned wall, and a nightstand with a lamp.

8. Embassy Suites by Hilton Portland Maine

2.9 km from Maine Medical Center

Kelly

NT$7,867

NT$8,704 total

includes taxes & fees

Sep 27 - Sep 28

A balcony with a table and chairs, overlooking a street with buildings and parked cars.

A restaurant with a brick fireplace, white chairs, and tables set for dining.

A reception area with two wooden reception desks labeled 'eighteen95 restaurant' and 'Valet'.

A hot tub area with a tiled floor, a wooden bench, a potted plant, and towels on a rack.

9. Portland Regency Hotel & Spa

Old Port, 1.8 km from Maine Medical Center

Arlene

NT$12,424

NT$13,746 total

includes taxes & fees

Sep 20 - Sep 21

A brick building with a grand entrance labeled "THE FRANCIS."

A balcony with a round table and orange chairs, overlooking a garden with various plants and flowers.

A living room with a grey sofa set, a wooden staircase, and a potted plant.

A reception area with a wooden desk, a fireplace, and a painting on the wall.

10. The Francis

Parkside, 0.3 km from Maine Medical Center

Jessica

NT$8,941

NT$10,695 total

includes taxes & fees

Sep 20 - Sep 21

A modern interior with a bar area, seating, and shelves with plants and books.

A rooftop terrace with a sofa, two chairs, and a small table, overlooking a cityscape and a body of water.

A modern restaurant with a bar area, wooden tables, and leather booths.

A cozy living room with a fireplace, two green armchairs, a coffee table, and a yellow ottoman.

11. The Press Hotel, Marriott Autograph Collection

Downtown Portland, 1.6 km from Maine Medical Center

Elizabeth

NT$14,700

NT$16,264 total

includes taxes & fees

Sep 27 - Sep 28

An outdoor seating area with a fire feature, comfortable seating, and a view of the cityscape.

A modern interior with wooden panel ceilings, a central seating area with sofas and tables, and a variety of decorative mirrors.

A modern interior with a fireplace, seating area, and large windows.

A modern living room with a fireplace, bookshelves, and comfortable seating.

12. Canopy by Hilton Portland Waterfront

Old Port, 1.5 km from Maine Medical Center

john

NT$15,205

NT$16,823 total

includes taxes & fees

Sep 20 - Sep 21

A waterfront marina with boats docked, buildings with multiple windows, and a red building with a visible restaurant.

A spacious lobby with a high ceiling, large chandeliers, and a mix of seating areas including sofas and armchairs.

A hotel lobby with a bar area, seating arrangements, and a fireplace.

A large indoor swimming pool with clear water, tiled flooring, and a seating area with chairs and a plant.

13. Hilton Garden Inn Portland Downtown Waterfront

Old Port, 2.1 km from Maine Medical Center

Jenna

NT$9,268

NT$10,254 total

includes taxes & fees

Sep 27 - Sep 28

A modern bar area with a wooden bar counter, black bar stools, and a contemporary light fixture.

A modern reception area with a central desk, seating arrangements, and large windows offering views of the cityscape.

A hotel room with a large bed, a sofa, a small table, and a bench. There is a window with a view of the water.

A black SUV parked in front of AC Hotel Portland, a modern building with a brick facade and large windows.

14. AC Hotel Portland Downtown/Waterfront, ME

Downtown Portland, 2.3 km from Maine Medical Center

Nicole Emily Elizabeth

NT$9,398

NT$10,398 total

includes taxes & fees

Sep 27 - Sep 28

A rooftop terrace with a modern outdoor seating area, a fire pit, and a view of the cityscape.

A modern bar area with a long counter, multiple stools, and a variety of bottles and glasses on shelves.

A modern lobby with a geometric wall design, seating area, and a large abstract artwork.

A modern living room with a sofa, armchairs, a coffee table, and a rug.

15. Cambria Hotel Portland Downtown-Old Port

Downtown Portland, 2.3 km from Maine Medical Center

Rebecca

NT$9,657

NT$11,547 total

includes taxes & fees

Sep 27 - Sep 28

A modern bar area with a bar counter, seating, and a view of the cityscape.

A modern living room with a grey sofa, a yellow armchair, and a red armchair. There are two floor lamps, a flat-screen TV, and patterned wallpaper.

A pool table with balls, a sofa, and a dining area with chairs and tables.

A hotel room with two beds, a TV, a desk, and a view of the city.

16. Aloft by Marriott Portland Downtown Waterfront ME

Downtown Portland, 1.4 km from Maine Medical Center

Raysa

NT$9,118

NT$10,088 total

includes taxes & fees

Oct 4 - Oct 5

A spacious lounge with leather seating, round tables, and large windows offering a view of a body of water and buildings.

The exterior of the Westin hotel with a prominent entrance and two bicycles parked in front.

A banquet hall with round tables, white tablecloths, and wooden chairs.

A bar area with a long counter, multiple stools, and a variety of bottles and glasses.

17. The Westin Portland Harborview

Downtown Portland, 0.9 km from Maine Medical Center

Lyudmila

NT$8,038

NT$8,893 total

includes taxes & fees

Sep 20 - Sep 21

A garden with a stone wall, various plants, and flowers.

A two-story house with a porch and a sign reading "Fleetwork House."

A bathroom with wooden cabinetry, a sink, a mirror, and framed artwork on the wall.

A dining table set with a fruit bowl, cutlery, and decorative elements like a pumpkin and autumn leaves.

18. Fleetwood House Bed & Breakfast

Rosemont, 2.7 km from Maine Medical Center

Karen

NT$7,246

NT$8,215 total

includes taxes & fees

Sep 17 - Sep 18

A balcony with wooden flooring, striped cushioned chairs, and a glass railing overlooking a cityscape at night.

A bar area with a polished granite countertop, a variety of liquor bottles, a fruit bowl, and blue upholstered bar stools.

A modern hotel room with a large bed, a desk, and a TV.

A bar area with a black countertop, blue bar stools, and a variety of bottles and glasses.

19. Hyatt Place Portland Downtown - Old Port Square

Old Port, 1.6 km from Maine Medical Center

Jeetindra

NT$9,462

NT$10,468 total

includes taxes & fees

Sep 20 - Sep 21

An outdoor patio area with wicker furniture, string lights, and a barbecue grill.

A brick building with a large entrance and a sign that reads "Residence Inn Marriott".

A hotel room with a bed, a TV, a nightstand, a window with a view of the water, and a wooden headboard.

A bar area with stools, a counter, and a herringbone-patterned wall.

20. Residence Inn by Marriott Portland Downtown/Waterfront

Downtown Portland, 2.3 km from Maine Medical Center

Greg

NT$9,462

NT$10,468 total

includes taxes & fees

Sep 20 - Sep 21

View all properties

Compare popular hotels close to Maine Medical Center

Property	Property class	Guest rating
Evalina Hotel	10.0 11 11 reviews	View
The Weldon Hotel	9.8 118 118 reviews	View
Blind Tiger Portland – Carleton Street	9.6 130 130 reviews	View
The Docent's Collection at 178 Middle Street	9.6 64 64 reviews	View
Longfellow Hotel	9.6 188 188 reviews	View

Top Maine Medical Center Hotel Reviews

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

10/10 Excellent

"Everything went smoothly. Clean room, lobby, lot, cafe. Excellent staff. We are scheduled to stay again in six days on our return. Look forward to it. Only thing I noticed lacking was soap in the bathroom off of the lobby. Hand sanitizer was available."

Portland Regency Hotel & Spa

8/10 Good

"Excellent location, great front of house staff. Historical building. Well designed rooms. Shuttle from airport."

Portland Harbor Hotel

8/10 Good

"Great location ."

Holiday Inn Portland-By the Bay by IHG

10/10 Excellent

"Location is about ten minute walk to the main areas of Commercial Street. Plenty of parking in the garage under the hotel. Room looked to be recently renovated and the bed was extremely comfortable. It was an enjoyable two night stay!"

Hilton Garden Inn Portland Downtown Waterfront

10/10 Excellent

"Wonderful view in room 602. You can watch the cruise ships come by and ferry taxi boats from the islands nearby. Also it’s close to all the restaurants and shops."

Longfellow Hotel

8/10 Good

"Clean nice hotel but not close to attractions. This is offset by free car service from the hotel"

Moxy Portland Thompson's Point

10/10 Excellent

"Wonderful stay while in town for a concert. Look forward to coming back!!"

Quality Inn & Suites South Portland

8/10 Good

"Bedding was clean, soft and warm. Room had a working tv, coffee maker and microwave. Complimentary breakfast was warm and delicious. Parking area was clean. Air conditioner worked but was loud. Bathroom door squeaked and room carpet along with stairway carpet really needed replacement or a really good shampoo. Room rate was good for my stay."

Hyatt Place Portland Downtown - Old Port Square

10/10 Excellent

"Staff was very helpful and pleasant."

Frequently asked questions

What's the area like around Maine Medical Center?

Maine Medical Center is located in a welcoming area of Portland known for its beautiful ocean views and sporting events. If you're looking for a convenient place to stay, check out the 196 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Maine Medical Center?

Adjacent to Maine Medical Center, Inn at St John Portland In-Town is one of the top choices for your stay based on our traveler data, and this B&B offers free breakfast and free parking. Other good options within a short distance include Clarion Hotel Portland Airport ME and La Quinta Inn & Suites by Wyndham Portland DT/Maine Med.

How many hotels are there close to Maine Medical Center?

Expedia has 196 hotels and other accommodations within a mile from Maine Medical Center.

If I need to cancel the hotel reservation for my stay near Maine Medical Center, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view top deals close to Maine Medical Center.

Where can I learn more about changing or cancelling my trip in the area near Maine Medical Center?

For additional details about changing or cancelling your stay near Maine Medical Center, click here.

What can I see and do near Maine Medical Center?

Portland Museum of Art, Maine Narrow Gauge Railroad, and International Cryptozoology Museum feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like State Theatre, Victoria Mansion, and Portland Head Light. You can watch performances at Merrill Auditorium, Port City Music Hall, and Portland Stage if you're interested in local theater.

Find hotels near Maine Medical Center, Portland from NT$8,215

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Maine Medical Center hotels

1. Evalina Hotel

2. The Weldon Hotel

3. Blind Tiger Portland – Carleton Street

4. The Docent's Collection at 178 Middle Street

5. Longfellow Hotel

6. The Docent's Collection at 121 Middle Street

7. Blind Tiger Portland - Danforth Street.

8. Embassy Suites by Hilton Portland Maine

9. Portland Regency Hotel & Spa

10. The Francis

11. The Press Hotel, Marriott Autograph Collection

12. Canopy by Hilton Portland Waterfront

13. Hilton Garden Inn Portland Downtown Waterfront

14. AC Hotel Portland Downtown/Waterfront, ME

15. Cambria Hotel Portland Downtown-Old Port

16. Aloft by Marriott Portland Downtown Waterfront ME

17. The Westin Portland Harborview

18. Fleetwood House Bed & Breakfast

19. Hyatt Place Portland Downtown - Old Port Square

20. Residence Inn by Marriott Portland Downtown/Waterfront

Compare popular hotels close to Maine Medical Center

Top Maine Medical Center Hotel Reviews

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

Portland Regency Hotel & Spa

Portland Harbor Hotel

Holiday Inn Portland-By the Bay by IHG

Hilton Garden Inn Portland Downtown Waterfront

Longfellow Hotel

Moxy Portland Thompson's Point

Quality Inn & Suites South Portland

Hyatt Place Portland Downtown - Old Port Square

Frequently asked questions

Explore a world of travel with Expedia