The Best Hotels Closest to Maine Medical Center in Portland for 2026

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Our top choices for Maine Medical Center hotels

A multi-story building with a stone facade, large windows, and a corner entrance.

A modern living room with a large window, a sofa, a coffee table, a TV, and a brick wall.

A modern living room with a large window, a TV, a sofa, a coffee table, and a dining area with a brick wall.

A spacious living area with exposed brick walls, a wooden staircase, and a large window offering a view of the city.

1. Evalina Hotel

Old Port, 1.7 km from Maine Medical Center

Rick

NT$9,805

NT$15,547 total

includes taxes & fees

Nov 17 - Nov 18

A modern kitchen with a central island, bar stools, a dining table, and a built-in oven.

A multi-story brick building with a modern design, featuring large windows and a flat roof.

A room with a round wooden table, two chairs, a potted plant, a large window, and a round mirror on the wall.

2. The Weldon Hotel

Downtown Portland, 1.4 km from Maine Medical Center

Victoria

NT$6,098

NT$9,076 total

includes taxes & fees

Nov 3 - Nov 4

A modern bar area with a counter and stools, surrounded by patterned chairs and a blue sofa.

A hotel room with a bed, a small table, and a window with curtains.

A multi-story brick building with a flat roof, large windows, and outdoor seating areas.

3. Longfellow Hotel

Parkside, 0.3 km from Maine Medical Center

thomas

NT$6,678

NT$8,642 total

includes taxes & fees

Nov 15 - Nov 16

4. West End Collection at 146 Pine

West End, 0.5 km from Maine Medical Center

Stephanie

NT$6,837

NT$7,452 total

includes taxes & fees

Nov 1 - Nov 2

A spacious living room with a large dining table, comfortable seating, and large windows offering views of the city.

A hotel room with a bed, a nightstand with a lamp, a mirror, a bathroom with a sink and a shower.

A modern living room with a sofa, coffee table, and chairs. There is a kitchen area with cabinets and a refrigerator.

A modern kitchen with a central island, stainless steel appliances, and wooden bar stools.

5. The Docent's Collection at 121 Middle Street

Old Port, 1.9 km from Maine Medical Center

Susan

NT$5,799

NT$6,321 total

includes taxes & fees

Nov 2 - Nov 3

A four-poster bed with a chandelier, a bedside table with books, and a view of a brick building through the windows.

A spacious kitchen with a central island, wooden bar stools, and a long dining table.

A wooden deck with two wicker chairs and a small table, overlooking a brick building with ivy and a fire escape.

A cozy room with a brick fireplace, a bench, and a table.

6. Blind Tiger Portland - Danforth Street.

West End, 1.1 km from Maine Medical Center

Mary

NT$8,165

NT$8,900 total

includes taxes & fees

Nov 9 - Nov 10

A well-lit living room with a fireplace, comfortable seating, and a large mirror.

A room with a wooden chair, a cushioned bench, a small table with books and vases, and a potted plant.

A staircase with a wooden handrail and a chandelier.

A red brick building with a classic facade, a front entrance with double doors, and a small porch area with potted plants.

7. Blind Tiger Portland – Carleton Street

West End, 0.4 km from Maine Medical Center

Ryan

NT$7,938

NT$8,652 total

includes taxes & fees

Nov 17 - Nov 18

A balcony with a table and chairs, overlooking a street with buildings and parked cars.

A bar area with multiple seating options, including bar stools and chairs, and a bar counter with a variety of bottles and glasses.

A restaurant with a brick fireplace, white chairs, and tables set for dining.

A reception area with two wooden reception desks labeled 'eighteen95 restaurant' and 'Valet'.

8. Portland Regency Hotel & Spa

Old Port, 1.8 km from Maine Medical Center

Brian

NT$4,104

NT$4,540 total

includes taxes & fees

Nov 3 - Nov 4

A modern interior with a fireplace, seating area, and large windows.

A modern living room with a fireplace, sofas, a coffee table, and a bookshelf.

A modern hotel room with a large bed, a wooden headboard, a bedside table with a lamp, and a view of the outdoors through a window.

A modern kitchen with a central island, pendant lighting, and built-in appliances.

9. Canopy by Hilton Portland Waterfront

Old Port, 1.5 km from Maine Medical Center

Abdolkarim

NT$5,060

NT$5,598 total

includes taxes & fees

Nov 17 - Nov 18

A brick building with a white entrance and the name "THE FRANCIS" above the door.

A room with a mustard-colored sofa, two round tables, and various framed artworks on the walls.

A reception area with a wooden desk, a fireplace, and a painting on the wall.

A balcony with a round table and orange chairs, overlooking a garden with various plants and flowers.

10. The Francis

Parkside, 0.3 km from Maine Medical Center

Graig

NT$4,225

NT$5,578 total

includes taxes & fees

Nov 4 - Nov 5

A modern interior with a bar area, seating, and shelves with plants and books.

A rooftop terrace with a sofa, two chairs, and a small table, overlooking a cityscape and a body of water.

A modern restaurant with a bar area, wooden tables, and leather booths.

A cozy living room with a fireplace, two green armchairs, a coffee table, and a yellow ottoman.

11. The Press Hotel, Marriott Autograph Collection

Downtown Portland, 1.6 km from Maine Medical Center

Mark

NT$6,445

NT$8,556 total

includes taxes & fees

Nov 8 - Nov 9

A modern bar area with a wooden bar counter, black bar stools, and a contemporary light fixture.

A modern reception area with a central desk, seating arrangements, and large windows offering views of the cityscape.

A modern living room with a sofa, two armchairs, a glass coffee table, and a decorative wall panel.

A black SUV parked in front of AC Hotel Portland, a modern building with a brick facade and large windows.

12. AC Hotel Portland Downtown/Waterfront, ME

Downtown Portland, 2.3 km from Maine Medical Center

Kin Mong

NT$3,564

NT$3,943 total

includes taxes & fees

Nov 16 - Nov 17

A rooftop terrace with a modern outdoor seating area, a fire pit, and a view of the cityscape.

A modern living room with a sofa, armchairs, a coffee table, and a rug.

A modern bar area with a long counter, multiple stools, and a variety of bottles and glasses on shelves.

A modern dining area with a dark blue booth seating, wooden ceiling beams, and large windows providing natural light.

13. Cambria Hotel Portland Downtown-Old Port

Downtown Portland, 2.3 km from Maine Medical Center

Sharion

NT$3,603

NT$4,869 total

includes taxes & fees

Nov 10 - Nov 11

A fire pit surrounded by wicker chairs in a garden setting.

A living room with a fireplace, seating area, and a large window.

A hotel room with a large bed, two bedside tables, a chair, a window with curtains, and a view of the city.

A spacious living area with large windows, a staircase, and modern furniture.

14. Portland Harbor Hotel

Old Port, 1.6 km from Maine Medical Center

Eric

NT$4,829

NT$6,579 total

includes taxes & fees

Nov 16 - Nov 17

A modern bar area with a long counter, multiple seating options, and a built-in fire feature.

A conference room with a stage featuring a large screen displaying the word 'Float' and a banner for the University of Maine.

A swimming pool with lounge chairs and tables, surrounded by a well-lit indoor area with a view of the outside.

A Holiday Inn hotel with a modern design, featuring a large entrance canopy and multiple floors.

15. Holiday Inn Portland-By the Bay by IHG

Portland Arts District, 1.2 km from Maine Medical Center

Fran

NT$3,273

NT$3,639 total

includes taxes & fees

Nov 1 - Nov 2

A modern bar area with a bar counter, seating, and a view of the cityscape.

A modern living room with a grey sofa, a yellow armchair, and a red armchair. There are two floor lamps, a flat-screen TV, and patterned wallpaper.

A pool table with balls, a sofa, and a dining area with chairs and tables.

A hotel room with two beds, a TV, a desk, and a view of the city.

16. Aloft by Marriott Portland Downtown Waterfront ME

Downtown Portland, 1.4 km from Maine Medical Center

Aubrey

NT$2,955

NT$3,269 total

includes taxes & fees

Nov 18 - Nov 19

The exterior of a Courtyard by Marriott hotel with a glass entrance, outdoor seating area, and a stone facade.

A restaurant with booths and tables, brick walls, and pendant lighting.

A modern hotel lobby with a reception desk, a seating area, and a large wall mural.

A modern bar area with leather seating, a bar counter, and a menu board.

17. Courtyard Portland Downtown/Waterfront

Old Port, 1.5 km from Maine Medical Center

reggie

NT$3,344

NT$3,700 total

includes taxes & fees

Nov 16 - Nov 17

A spacious lounge with leather seating, round tables, and large windows offering a view of a body of water and buildings.

The exterior of the Westin hotel with a prominent entrance and two bicycles parked in front.

A modern hotel lobby with a large chandelier, reception desk, and a staircase leading to other areas.

A banquet hall with round tables, white tablecloths, and wooden chairs.

18. The Westin Portland Harborview

Downtown Portland, 0.9 km from Maine Medical Center

Samuel

NT$3,499

NT$3,872 total

includes taxes & fees

Nov 18 - Nov 19

A balcony with wooden flooring, striped cushioned chairs, and a glass railing overlooking a cityscape at night.

A modern hotel with a dark facade, multiple windows, and a visible sign for 'Hyatt Place'.

A modern hotel room with a large bed, a desk, and a TV.

A bar area with a polished granite countertop, a variety of liquor bottles, a fruit bowl, and blue upholstered bar stools.

19. Hyatt Place Portland Downtown - Old Port Square

Old Port, 1.6 km from Maine Medical Center

Kelly

NT$4,180

NT$4,624 total

includes taxes & fees

Nov 2 - Nov 3

An outdoor patio area with wicker furniture, string lights, and a barbecue grill.

A hotel room with a bed, a TV, a nightstand, a window with a view of the water, and a wooden headboard.

A bar area with stools, a counter, and a herringbone-patterned wall.

A brick building with a large entrance and a sign that reads "Residence Inn Marriott".

20. Residence Inn by Marriott Portland Downtown/Waterfront

Downtown Portland, 2.3 km from Maine Medical Center

Tim

NT$3,564

NT$3,943 total

includes taxes & fees

Nov 2 - Nov 3

View all properties

Compare popular hotels close to Maine Medical Center

Property	Property class	Guest rating
Evalina Hotel	10.0 Exceptional 15 reviews	View
The Weldon Hotel	9.8 Exceptional 126 reviews	View
Longfellow Hotel	9.6 Exceptional 195 reviews	View
West End Collection at 146 Pine	9.6 Exceptional 100 reviews	View
The Docent's Collection at 121 Middle Street	9.6 Exceptional 417 reviews	View

Top Maine Medical Center Hotel Reviews

Hampton Inn Portland Downtown - Waterfront

10/10 Excellent

"Perfect location to Commercial Street, dining and shopping. Perfect for families. Excellent experience!"

Hyatt Place Portland Downtown - Old Port Square

10/10 Excellent

"I loved our stay in Portland. We had a beautiful room, it was clean, the bed was comfy, breakfast was good, and you couldn't ask for a better location for exploring Portland."

Holiday Inn Portland-By the Bay by IHG

10/10 Excellent

"The breakfast is great and the staffs are very friendly!"

Aloft by Marriott Portland Downtown Waterfront ME

8/10 Good

"Room was clean, no food options except for a little shop inside the reception. Very good location"

Cambria Hotel Portland Downtown-Old Port

10/10 Excellent

"Room was very comfortable. Great shower. Nice bar. Great location!!"

Courtyard Portland Downtown/Waterfront

10/10 Excellent

"Great waterfront location in Portland. Convenient to airport, shopping and restaurants."

Inn at St John Portland In-Town

10/10 Excellent

"We love to stay at historic places when we travel, and we were not disappointed with this one! So cute and cozy!"

West End Collection at 146 Pine

10/10 Excellent

"This was a super cute boutique inn and the location was ideal. The staff was super friendly!"

Frequently asked questions

What's the area like around Maine Medical Center?

Maine Medical Center is located in a welcoming area of Portland known for its beautiful ocean views and sporting events. If you're looking for a convenient place to stay, check out the 195 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Maine Medical Center?

Adjacent to Maine Medical Center, Inn at St John Portland In-Town is one of the top choices for your stay based on our traveler data, and this B&B offers free breakfast and free parking. Other good options within a short distance include Clarion Hotel Portland Airport ME and La Quinta Inn & Suites by Wyndham Portland DT/Maine Med.

How many hotels are there close to Maine Medical Center?

Expedia has 195 hotels and other accommodations within a mile from Maine Medical Center.

If I need to cancel the hotel reservation for my stay near Maine Medical Center, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view top deals close to Maine Medical Center.

Where can I learn more about changing or cancelling my trip in the area near Maine Medical Center?

For additional details about changing or cancelling your stay near Maine Medical Center, click here.

What can I see and do near Maine Medical Center?

Portland Museum of Art, Maine Narrow Gauge Railroad, and International Cryptozoology Museum feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like State Theatre, Victoria Mansion, and Portland Head Light. You can watch performances at Merrill Auditorium, Port City Music Hall, and Portland Stage if you're interested in local theater.

Find hotels near Maine Medical Center, Portland from NT$3,269

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Treat yourself

Be picky

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Our top choices for Maine Medical Center hotels

1. Evalina Hotel

2. The Weldon Hotel

3. Longfellow Hotel

4. West End Collection at 146 Pine

5. The Docent's Collection at 121 Middle Street

6. Blind Tiger Portland - Danforth Street.

7. Blind Tiger Portland – Carleton Street

8. Portland Regency Hotel & Spa

9. Canopy by Hilton Portland Waterfront

10. The Francis

11. The Press Hotel, Marriott Autograph Collection

12. AC Hotel Portland Downtown/Waterfront, ME

13. Cambria Hotel Portland Downtown-Old Port

14. Portland Harbor Hotel

15. Holiday Inn Portland-By the Bay by IHG

16. Aloft by Marriott Portland Downtown Waterfront ME

17. Courtyard Portland Downtown/Waterfront

18. The Westin Portland Harborview

19. Hyatt Place Portland Downtown - Old Port Square

20. Residence Inn by Marriott Portland Downtown/Waterfront

Compare popular hotels close to Maine Medical Center

Top Maine Medical Center Hotel Reviews

Hampton Inn Portland Downtown - Waterfront

Hyatt Place Portland Downtown - Old Port Square

Holiday Inn Portland-By the Bay by IHG

Aloft by Marriott Portland Downtown Waterfront ME

Cambria Hotel Portland Downtown-Old Port

Courtyard Portland Downtown/Waterfront

Inn at St John Portland In-Town

West End Collection at 146 Pine

Frequently asked questions

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