The Best Hotels Closest to Maine Medical Center in Portland for 2026

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Our top choices for Maine Medical Center hotels

A multi-story building with a stone facade, large windows, and a corner entrance.

A spacious living area with exposed brick walls, a wooden staircase, and a large window offering a view of the city.

A modern kitchen with a central island, wooden beams on the ceiling, and a dining area with a round table and chairs.

A modern living room with a large window, a sofa, a coffee table, a TV, and a brick wall.

1. Evalina Hotel

Old Port, 1.7 km from Maine Medical Center

Eric

NT$12,225

NT$18,128 total

includes taxes & fees

Nov 2 - Nov 3

A modern kitchen with a central island, bar stools, a dining table, and a built-in oven.

A room with a round wooden table, two chairs, a potted plant, a large window, and a round mirror on the wall.

A multi-story brick building with a modern design, featuring large windows and a flat roof.

2. The Weldon Hotel

Downtown Portland, 1.4 km from Maine Medical Center

Victoria

NT$6,804

NT$9,818 total

includes taxes & fees

Nov 2 - Nov 3

A brick building with a sign reading "WAYPOINT" and outdoor seating with tables, chairs, and a fire pit.

A spacious lobby with multiple seating areas, a fireplace, and large windows.

A swimming pool with clear blue water, surrounded by lounge chairs and a brick wall.

A chef in a black uniform and white hat, holding a ladle and a bowl, with various dishes in front of him.

3. Embassy Suites by Hilton Portland Maine

2.9 km from Maine Medical Center

Andrew

NT$4,055

NT$4,486 total

includes taxes & fees

Nov 1 - Nov 2

A balcony with a table and chairs, overlooking a street with buildings and parked cars.

A reception area with two wooden reception desks labeled 'eighteen95 restaurant' and 'Valet'.

A hot tub area with a tiled floor, a wooden bench, a potted plant, and towels on a rack.

A bar area with multiple seating options, including bar stools and chairs, and a bar counter with a variety of bottles and glasses.

4. Portland Regency Hotel & Spa

Old Port, 1.8 km from Maine Medical Center

SHELBY

NT$4,289

NT$4,746 total

includes taxes & fees

Nov 2 - Nov 3

A waterfront marina with boats docked, buildings with multiple windows, and a red building with a visible restaurant.

A hotel lobby with a bar area, seating arrangements, and a fireplace.

A large indoor swimming pool with clear water, tiled flooring, and a seating area with chairs and a plant.

A spacious lobby with a high ceiling, large chandeliers, and a mix of seating areas including sofas and armchairs.

5. Hilton Garden Inn Portland Downtown Waterfront

Old Port, 2.1 km from Maine Medical Center

Jenna

NT$3,945

NT$4,365 total

includes taxes & fees

Nov 2 - Nov 3

An outdoor seating area with a fire feature, comfortable seating, and a view of the cityscape.

A modern bar with a long counter, multiple bar stools, and a large window offering a view of the cityscape.

A modern living room with a fireplace, bookshelves, and comfortable seating.

A modern interior with a fireplace, seating area, and large windows.

6. Canopy by Hilton Portland Waterfront

Old Port, 1.5 km from Maine Medical Center

john

NT$5,860

NT$6,484 total

includes taxes & fees

Nov 2 - Nov 3

A modern interior with a bar area, seating, and shelves with plants and books.

A modern living room with a large sectional sofa, a dining area with a kitchen in the background, and large windows offering a city view.

A cozy living room with a fireplace, two green armchairs, a coffee table, and a yellow ottoman.

A modern restaurant with a bar area, wooden tables, and leather booths.

7. The Press Hotel, Marriott Autograph Collection

Downtown Portland, 1.6 km from Maine Medical Center

Mark

NT$7,030

NT$9,186 total

includes taxes & fees

Nov 1 - Nov 2

A fire pit surrounded by wicker chairs in a garden setting.

A living room with a fireplace, seating area, and a large window.

A spacious living area with large windows, a staircase, and modern furniture.

A hotel room with a large bed, two bedside tables, a chair, a window with curtains, and a view of the city.

8. Portland Harbor Hotel

Old Port, 1.6 km from Maine Medical Center

Teresa

NT$5,419

NT$7,217 total

includes taxes & fees

Nov 1 - Nov 2

A rooftop terrace with a modern outdoor seating area, a fire pit, and a view of the cityscape.

A modern dining area with a dark blue booth seating, wooden ceiling beams, and large windows providing natural light.

A modern lobby with a geometric wall design, seating area, and a large abstract artwork.

A modern living room with a sofa, armchairs, a coffee table, and a rug.

9. Cambria Hotel Portland Downtown-Old Port

Downtown Portland, 2.3 km from Maine Medical Center

Sharion

NT$3,560

NT$4,811 total

includes taxes & fees

Nov 1 - Nov 2

A modern bar area with a wooden bar counter, black bar stools, and a contemporary light fixture.

A modern reception area with a central desk, seating arrangements, and large windows offering views of the cityscape.

A hotel room with a large bed, a sofa, a small table, and a bench. There is a window with a view of the water.

A modern living room with a sofa, two armchairs, a glass coffee table, and a decorative wall panel.

10. AC Hotel Portland Downtown/Waterfront, ME

Downtown Portland, 2.3 km from Maine Medical Center

Paul

NT$3,906

NT$4,321 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor patio area with wicker furniture, string lights, and a barbecue grill.

A bar area with stools, a counter, and a herringbone-patterned wall.

A swimming pool with a tiled deck, lounge chairs, and a ceiling with recessed lighting.

A brick building with a large entrance and a sign that reads "Residence Inn Marriott".

11. Residence Inn by Marriott Portland Downtown/Waterfront

Downtown Portland, 2.3 km from Maine Medical Center

Tim

NT$3,778

NT$4,179 total

includes taxes & fees

Nov 1 - Nov 2

A modern bar area with a long counter, multiple seating options, and a built-in fire feature.

A modern bar area with seating and a bar counter.

A Holiday Inn hotel with a modern design, featuring a large entrance canopy and multiple floors.

A conference room with a stage featuring a large screen displaying the word 'Float' and a banner for the University of Maine.

12. Holiday Inn Portland-By the Bay by IHG

Portland Arts District, 1.2 km from Maine Medical Center

CHARLES

NT$3,297

NT$3,648 total

includes taxes & fees

Nov 1 - Nov 2

A modern bar area with a bar counter, seating, and a view of the cityscape.

A pool table with balls, a sofa, and a dining area with chairs and tables.

A hotel room with two beds, a TV, a desk, and a view of the city.

A modern hotel entrance with a glass facade, outdoor seating, and a well-lit lobby area.

13. Aloft by Marriott Portland Downtown Waterfront ME

Downtown Portland, 1.4 km from Maine Medical Center

susan

NT$3,102

NT$3,432 total

includes taxes & fees

Nov 1 - Nov 2

The exterior of a Courtyard by Marriott hotel with a glass entrance, outdoor seating area, and a stone facade.

A modern bar area with leather seating, a bar counter, and a menu board.

A hotel room with a large bed, a desk with a computer, a TV, and a view of the city and water.

A modern hotel lobby with a reception desk, a seating area, and a large wall mural.

14. Courtyard Portland Downtown/Waterfront

Old Port, 1.5 km from Maine Medical Center

Laura

NT$3,816

NT$4,222 total

includes taxes & fees

Nov 1 - Nov 2

A balcony with wooden flooring, striped cushioned chairs, and a glass railing overlooking a cityscape at night.

A modern hotel room with a large bed, a desk, and a TV.

A modern hotel with a dark facade, multiple windows, and a visible sign for 'Hyatt Place'.

A bar area with a black countertop, blue bar stools, and a variety of bottles and glasses.

15. Hyatt Place Portland Downtown - Old Port Square

Old Port, 1.6 km from Maine Medical Center

Jeetindra

NT$4,130

NT$4,569 total

includes taxes & fees

Nov 2 - Nov 3

A spacious lounge with leather seating, round tables, and large windows offering a view of a body of water and buildings.

The exterior of the Westin hotel with a prominent entrance and two bicycles parked in front.

A modern hotel lobby with a large chandelier, reception desk, and a staircase leading to other areas.

A banquet hall with round tables, white tablecloths, and wooden chairs.

16. The Westin Portland Harborview

Downtown Portland, 0.9 km from Maine Medical Center

Kathleen

NT$4,322

NT$4,782 total

includes taxes & fees

Nov 1 - Nov 2

A modern hotel lobby with a reception desk, a coffee station, and a tiled wall.

A hotel lobby with a sofa, chairs, a TV, and a breakfast sign.

A modern living room with a fireplace, comfortable seating, and a flat-screen TV.

17. La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

0.6 km from Maine Medical Center

Joseph

NT$2,564

NT$2,837 total

includes taxes & fees

Nov 1 - Nov 2

A multi-story hotel with 'Resilience Inn' and 'Mozy Hotels' signage, featuring a modern brick facade and multiple ground-level retail spaces.

A conference room with a wooden table, leather chairs, and a bookshelf with various decorative items.

A hotel reception area with a bar, seating, and a staircase.

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

18. Moxy Portland Thompson's Point

1.4 km from Maine Medical Center

Brianna

NT$3,714

NT$4,109 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with a sofa, chairs, a coffee table, and a TV.

A bar area with wooden bar stools, a television, and a liquor display. There are red chairs and a small table with a glass top.

A lobby with a reception desk, a clock, a plant, and a round table.

A hotel dining area with multiple wooden tables and chairs, a patterned carpet, and wall-mounted artwork depicting coastal scenes.

19. Clarion Hotel Portland Airport ME

1.3 km from Maine Medical Center

Leonard

NT$2,267

NT$2,508 total

includes taxes & fees

Nov 1 - Nov 2

A bedroom with a bed, a nightstand, a lamp, a window, and a framed picture on the wall.

A room with a white fireplace, a round mirror above a sink, and a chair with a blanket.

A dining area with round tables, chairs, and a view of buildings through large windows.

A cozy living room with a fireplace, a sofa, a coffee table, and a person reading a book.

20. West End Collection at 49 Neal

West End, 0.6 km from Maine Medical Center

NT$7,875

NT$8,584 total

includes taxes & fees

Nov 1 - Nov 2

View all properties

Compare popular hotels close to Maine Medical Center

Property	Property class	Guest rating
Evalina Hotel	10.0 Exceptional 13 reviews	View
The Weldon Hotel	9.8 Exceptional 122 reviews	View
Embassy Suites by Hilton Portland Maine	9.4 Exceptional 1,177 reviews	View
Portland Regency Hotel & Spa	9.4 Exceptional 1,768 reviews	View
Hilton Garden Inn Portland Downtown Waterfront	9.4 Exceptional 1,016 reviews	View

Top Maine Medical Center Hotel Reviews

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

10/10 Excellent

"Clean, friendly staff"

Portland Regency Hotel & Spa

10/10 Excellent

"Amazing location. Beautiful historic hotel. Loved it!!"

Clarion Hotel Portland Airport ME

8/10 Good

"When we checked in the room was freezing (AC on in Oct!) and reeked of air freshener, which gotten into all the bedding and my clothes. I am allergic to fragrance as are many people."

Quality Inn & Suites South Portland

10/10 Excellent

"Good place to crash"

Holiday Inn Portland-By the Bay by IHG

10/10 Excellent

"Very friendly and professional staff in the lobby. Portland Wharf has great restaurants and beautiful views in Downtown"

Hyatt Place Portland Downtown - Old Port Square

10/10 Excellent

"Clean and comfortable rooms. Staff was nice. Good location"

The Francis

10/10 Excellent

"Excellent property. Easy to find. Very friendly and helpful staff. Beautiful in every respect. Great place. Would definitely return."

Aloft by Marriott Portland Downtown Waterfront ME

10/10 Excellent

"Very clean room, centrally located, and the staff was very nice."

West End Collection at 146 Pine

10/10 Excellent

"This was a super cute boutique inn and the location was ideal. The staff was super friendly!"

Frequently asked questions

What's the area like around Maine Medical Center?

Maine Medical Center is located in a welcoming area of Portland known for its beautiful ocean views and sporting events. If you're looking for a convenient place to stay, check out the 195 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Maine Medical Center?

Adjacent to Maine Medical Center, Inn at St John Portland In-Town is one of the top choices for your stay based on our traveler data, and this B&B offers free breakfast and free parking. Other good options within a short distance include Clarion Hotel Portland Airport ME and La Quinta Inn & Suites by Wyndham Portland DT/Maine Med.

How many hotels are there close to Maine Medical Center?

Expedia has 195 hotels and other accommodations within a mile from Maine Medical Center.

If I need to cancel the hotel reservation for my stay near Maine Medical Center, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view top deals close to Maine Medical Center.

Where can I learn more about changing or cancelling my trip in the area near Maine Medical Center?

For additional details about changing or cancelling your stay near Maine Medical Center, click here.

What can I see and do near Maine Medical Center?

Portland Museum of Art, Maine Narrow Gauge Railroad, and International Cryptozoology Museum feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like State Theatre, Victoria Mansion, and Portland Head Light. You can watch performances at Merrill Auditorium, Port City Music Hall, and Portland Stage if you're interested in local theater.

Find hotels near Maine Medical Center, Portland from NT$2,508

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Treat yourself

Be picky

Check prices for these dates

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Star rating

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Our top choices for Maine Medical Center hotels

1. Evalina Hotel

2. The Weldon Hotel

3. Embassy Suites by Hilton Portland Maine

4. Portland Regency Hotel & Spa

5. Hilton Garden Inn Portland Downtown Waterfront

6. Canopy by Hilton Portland Waterfront

7. The Press Hotel, Marriott Autograph Collection

8. Portland Harbor Hotel

9. Cambria Hotel Portland Downtown-Old Port

10. AC Hotel Portland Downtown/Waterfront, ME

11. Residence Inn by Marriott Portland Downtown/Waterfront

12. Holiday Inn Portland-By the Bay by IHG

13. Aloft by Marriott Portland Downtown Waterfront ME

14. Courtyard Portland Downtown/Waterfront

15. Hyatt Place Portland Downtown - Old Port Square

16. The Westin Portland Harborview

17. La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

18. Moxy Portland Thompson's Point

19. Clarion Hotel Portland Airport ME

20. West End Collection at 49 Neal

Compare popular hotels close to Maine Medical Center

Top Maine Medical Center Hotel Reviews

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

Portland Regency Hotel & Spa

Clarion Hotel Portland Airport ME

Quality Inn & Suites South Portland

Holiday Inn Portland-By the Bay by IHG

Hyatt Place Portland Downtown - Old Port Square

The Francis

Aloft by Marriott Portland Downtown Waterfront ME

West End Collection at 146 Pine

Frequently asked questions

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