The Best Hotels Closest to Maine Medical Center in Portland for 2026

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Our top choices for Maine Medical Center hotels

A multi-story building with a stone facade, large windows, and a corner entrance.

A spacious living area with exposed brick walls, a wooden staircase, and a large window offering a view of the city.

A modern living room with a large window, a sofa, a coffee table, a TV, and a brick wall.

A modern living room with a large window, a TV, a sofa, a coffee table, and a dining area with a brick wall.

1. Evalina Hotel

Old Port, 1.7 km from Maine Medical Center

Eric

NT$10,441

NT$16,160 total

includes taxes & fees

Nov 3 - Nov 4

A spacious living room with a large window, a round coffee table, and two wooden chairs.

A modern kitchen with a bar area, large windows, and a flat-screen TV.

A modern kitchen with white cabinetry, a marble backsplash, two wooden stools, and a potted plant.

A hotel room with a large bed, a headboard, a nightstand, a TV mounted on the wall, and a window with a view of buildings outside.

2. The Docent's Collection at 178 Middle Street

Old Port, 1.7 km from Maine Medical Center

Michael

NT$6,909

NT$7,531 total

includes taxes & fees

Oct 25 - Oct 26

A modern kitchen with a central island, bar stools, a dining table, and a built-in oven.

A room with a round wooden table, two chairs, a potted plant, a large window, and a round mirror on the wall.

A multi-story brick building with a modern design, featuring large windows and a flat roof.

3. The Weldon Hotel

Downtown Portland, 1.4 km from Maine Medical Center

Victoria

NT$6,537

NT$9,515 total

includes taxes & fees

Nov 2 - Nov 3

A modern bar area with a counter and stools, surrounded by patterned chairs and a blue sofa.

A hotel room with a bed, a small table, and a window with curtains.

A multi-story brick building with a flat roof, large windows, and outdoor seating areas.

4. Longfellow Hotel

Parkside, 0.3 km from Maine Medical Center

thomas

NT$5,993

NT$7,863 total

includes taxes & fees

Nov 1 - Nov 2

A spacious living room with a large dining table, comfortable seating, and large windows offering views of the city.

A modern kitchen with a central island, stainless steel appliances, and wooden bar stools.

A hotel room with a bed, a nightstand with a lamp, a mirror, a bathroom with a sink and a shower.

A modern living room with a sofa, coffee table, and chairs. There is a kitchen area with cabinets and a refrigerator.

5. The Docent's Collection at 121 Middle Street

Old Port, 1.9 km from Maine Medical Center

Susan

NT$6,661

NT$7,260 total

includes taxes & fees

Nov 2 - Nov 3

A four-poster bed with a chandelier, a bedside table with books, and a view of a brick building through the windows.

A living room with a fireplace, a sofa, a coffee table, and a bookshelf.

A cozy room with a brick fireplace, a bench, and a table.

A wooden deck with two wicker chairs and a small table, overlooking a brick building with ivy and a fire escape.

6. Blind Tiger Portland - Danforth Street.

West End, 1.1 km from Maine Medical Center

Mary

NT$9,335

NT$10,175 total

includes taxes & fees

Nov 1 - Nov 2

A well-lit living room with a fireplace, comfortable seating, and a large mirror.

A hotel room with a checkered bedspread, a large mirror above the bed, and two windows with curtains.

A staircase with a wooden handrail and a chandelier.

A red brick building with a classic facade, a front entrance with double doors, and a small porch area with potted plants.

7. Blind Tiger Portland – Carleton Street

West End, 0.4 km from Maine Medical Center

Samuel

NT$8,993

NT$9,802 total

includes taxes & fees

Nov 1 - Nov 2

A balcony with a table and chairs, overlooking a street with buildings and parked cars.

A bar area with multiple seating options, including bar stools and chairs, and a bar counter with a variety of bottles and glasses.

A hot tub area with a tiled floor, a wooden bench, a potted plant, and towels on a rack.

A reception area with two wooden reception desks labeled 'eighteen95 restaurant' and 'Valet'.

8. Portland Regency Hotel & Spa

Old Port, 1.8 km from Maine Medical Center

Susan

NT$4,035

NT$4,465 total

includes taxes & fees

Nov 4 - Nov 5

A waterfront marina with boats docked, buildings with multiple windows, and a red building with a visible restaurant.

A hotel lobby with a bar area, seating arrangements, and a fireplace.

A large indoor swimming pool with clear water, tiled flooring, and a seating area with chairs and a plant.

A spacious lobby with a high ceiling, large chandeliers, and a mix of seating areas including sofas and armchairs.

9. Hilton Garden Inn Portland Downtown Waterfront

Old Port, 2.1 km from Maine Medical Center

Jenna

NT$4,176

NT$4,620 total

includes taxes & fees

Nov 2 - Nov 3

A brick building with a white entrance and the name "THE FRANCIS" above the door.

A reception area with a wooden desk, a fireplace, and a painting on the wall.

A living room with a grey sofa set, a wooden staircase, and a potted plant.

A room with a mustard-colored sofa, two round tables, and various framed artworks on the walls.

10. The Francis

Parkside, 0.3 km from Maine Medical Center

Kristin

NT$4,155

NT$5,485 total

includes taxes & fees

Nov 4 - Nov 5

An outdoor seating area with a fire feature, comfortable seating, and a view of the cityscape.

A modern living room with a fireplace, bookshelves, and comfortable seating.

A modern bar with a long counter, multiple bar stools, and a large window offering a view of the cityscape.

A modern interior with a fireplace, seating area, and large windows.

11. Canopy by Hilton Portland Waterfront

Old Port, 1.5 km from Maine Medical Center

john

NT$5,721

NT$6,330 total

includes taxes & fees

Nov 2 - Nov 3

A modern interior with a bar area, seating, and shelves with plants and books.

A modern restaurant with a bar area, wooden tables, and leather booths.

A cozy living room with a fireplace, two green armchairs, a coffee table, and a yellow ottoman.

A modern living room with a large sectional sofa, a dining area with a kitchen in the background, and large windows offering a city view.

12. The Press Hotel, Marriott Autograph Collection

Downtown Portland, 1.6 km from Maine Medical Center

Mark

NT$6,997

NT$9,143 total

includes taxes & fees

Nov 1 - Nov 2

A rooftop terrace with a modern outdoor seating area, a fire pit, and a view of the cityscape.

A modern living room with a sofa, armchairs, a coffee table, and a rug.

A modern dining area with a dark blue booth seating, wooden ceiling beams, and large windows providing natural light.

A modern lobby with a geometric wall design, seating area, and a large abstract artwork.

13. Cambria Hotel Portland Downtown-Old Port

Downtown Portland, 2.3 km from Maine Medical Center

Sharion

NT$3,543

NT$4,788 total

includes taxes & fees

Nov 1 - Nov 2

A fire pit surrounded by wicker chairs in a garden setting.

A hotel room with a large bed, two bedside tables, a chair, a window with curtains, and a view of the city.

A dining area with round tables and chairs, a view of the garden through large windows, and a cozy atmosphere.

A spacious living area with large windows, a staircase, and modern furniture.

14. Portland Harbor Hotel

Old Port, 1.6 km from Maine Medical Center

Teresa

NT$5,394

NT$7,183 total

includes taxes & fees

Nov 1 - Nov 2

A modern bar area with a wooden bar counter, black bar stools, and a contemporary light fixture.

A modern living room with a sofa, two armchairs, a glass coffee table, and a decorative wall panel.

A hotel room with a large bed, a sofa, a small table, and a bench. There is a window with a view of the water.

A modern reception area with a central desk, seating arrangements, and large windows offering views of the cityscape.

15. AC Hotel Portland Downtown/Waterfront, ME

Downtown Portland, 2.3 km from Maine Medical Center

Paul

NT$3,887

NT$4,301 total

includes taxes & fees

Nov 1 - Nov 2

A modern bar area with a long counter, multiple seating options, and a built-in fire feature.

A swimming pool with lounge chairs and tables, surrounded by a well-lit indoor area with a view of the outside.

A conference room with a stage featuring a large screen displaying the word 'Float' and a banner for the University of Maine.

A Holiday Inn hotel with a modern design, featuring a large entrance canopy and multiple floors.

16. Holiday Inn Portland-By the Bay by IHG

Portland Arts District, 1.2 km from Maine Medical Center

CHARLES

NT$3,282

NT$3,631 total

includes taxes & fees

Nov 3 - Nov 4

A modern bar area with a bar counter, seating, and a view of the cityscape.

A hotel room with two beds, a TV, a desk, and a view of the city.

A modern living room with a grey sofa, a yellow armchair, and a red armchair. There are two floor lamps, a flat-screen TV, and patterned wallpaper.

A modern hotel entrance with a glass facade, outdoor seating, and a well-lit lobby area.

17. Aloft by Marriott Portland Downtown Waterfront ME

Downtown Portland, 1.4 km from Maine Medical Center

susan

NT$3,087

NT$3,416 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lounge with leather seating, round tables, and large windows offering a view of a body of water and buildings.

A banquet hall with round tables, white tablecloths, and wooden chairs.

A bar area with a long counter, multiple stools, and a variety of bottles and glasses.

A modern hotel lobby with a large chandelier, reception desk, and a staircase leading to other areas.

18. The Westin Portland Harborview

Downtown Portland, 0.9 km from Maine Medical Center

Samuel

NT$4,301

NT$4,759 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor patio area with wicker furniture, string lights, and a barbecue grill.

A bar area with stools, a counter, and a herringbone-patterned wall.

A swimming pool with a tiled deck, lounge chairs, and a ceiling with recessed lighting.

A hotel room with a bed, a TV, a nightstand, a window with a view of the water, and a wooden headboard.

19. Residence Inn by Marriott Portland Downtown/Waterfront

Downtown Portland, 2.3 km from Maine Medical Center

Tim

NT$3,760

NT$4,160 total

includes taxes & fees

Nov 1 - Nov 2

The exterior of a Courtyard by Marriott hotel with a glass entrance, outdoor seating area, and a stone facade.

A modern bar area with leather seating, a bar counter, and a menu board.

A restaurant with booths and tables, brick walls, and pendant lighting.

A modern hotel lobby with a reception desk, a seating area, and a large wall mural.

20. Courtyard Portland Downtown/Waterfront

Old Port, 1.5 km from Maine Medical Center

Laura

NT$3,798

NT$4,202 total

includes taxes & fees

Nov 1 - Nov 2

View all properties

Compare popular hotels close to Maine Medical Center

Property	Property class	Guest rating
Evalina Hotel	10.0 Exceptional 13 reviews	View
The Docent's Collection at 178 Middle Street	9.8 Exceptional 72 reviews	View
The Weldon Hotel	9.8 Exceptional 123 reviews	View
Longfellow Hotel	9.6 Exceptional 192 reviews	View
The Docent's Collection at 121 Middle Street	9.6 Exceptional 403 reviews	View

Top Maine Medical Center Hotel Reviews

The Westin Portland Harborview

10/10 Excellent

"Room was clean. Bed was comfy. Breakfast was amazing. Great stay."

Quality Inn & Suites South Portland

10/10 Excellent

"Good for the cost"

Clarion Hotel Portland Airport ME

8/10 Good

"Easy check in, clean, good location."

Holiday Inn Portland-By the Bay by IHG

8/10 Good

"free shuttle service into town, front desk offered restaurant ideas that were not in their book."

Hilton Garden Inn Portland Downtown Waterfront

10/10 Excellent

"The Hilton Garden Inn was an extremely nice property. The onsite restaurant had several good options for eating with a pleasant ambience. It's location was perfect for walking distance access to many other wonderful restaurants and just across the street from the Casco Bay cruise line. Highly recommend this hotel!"

Moxy Portland Thompson's Point

10/10 Excellent

"We’re not informed about the $45 per day parking charge for the valet parking."

Inn at St John Portland In-Town

8/10 Good

"Limited parking close to the building was an issue. I had to wait for a parking spot.Also some hot choice for the breakfast buffet would have been appreciated."

Aloft by Marriott Portland Downtown Waterfront ME

10/10 Excellent

"Very clean room, centrally located, and the staff was very nice."

West End Collection at 146 Pine

10/10 Excellent

"This was a super cute boutique inn and the location was ideal. The staff was super friendly!"

Frequently asked questions

What's the area like around Maine Medical Center?

Maine Medical Center is located in a welcoming area of Portland known for its beautiful ocean views and sporting events. If you're looking for a convenient place to stay, check out the 195 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Maine Medical Center?

Adjacent to Maine Medical Center, Inn at St John Portland In-Town is one of the top choices for your stay based on our traveler data, and this B&B offers free breakfast and free parking. Other good options within a short distance include Clarion Hotel Portland Airport ME and La Quinta Inn & Suites by Wyndham Portland DT/Maine Med.

How many hotels are there close to Maine Medical Center?

Expedia has 195 hotels and other accommodations within a mile from Maine Medical Center.

If I need to cancel the hotel reservation for my stay near Maine Medical Center, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view top deals close to Maine Medical Center.

Where can I learn more about changing or cancelling my trip in the area near Maine Medical Center?

For additional details about changing or cancelling your stay near Maine Medical Center, click here.

What can I see and do near Maine Medical Center?

Portland Museum of Art, Maine Narrow Gauge Railroad, and International Cryptozoology Museum feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like State Theatre, Victoria Mansion, and Portland Head Light. You can watch performances at Merrill Auditorium, Port City Music Hall, and Portland Stage if you're interested in local theater.

Find hotels near Maine Medical Center, Portland from NT$3,416

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Maine Medical Center hotels

1. Evalina Hotel

2. The Docent's Collection at 178 Middle Street

3. The Weldon Hotel

4. Longfellow Hotel

5. The Docent's Collection at 121 Middle Street

6. Blind Tiger Portland - Danforth Street.

7. Blind Tiger Portland – Carleton Street

8. Portland Regency Hotel & Spa

9. Hilton Garden Inn Portland Downtown Waterfront

10. The Francis

11. Canopy by Hilton Portland Waterfront

12. The Press Hotel, Marriott Autograph Collection

13. Cambria Hotel Portland Downtown-Old Port

14. Portland Harbor Hotel

15. AC Hotel Portland Downtown/Waterfront, ME

16. Holiday Inn Portland-By the Bay by IHG

17. Aloft by Marriott Portland Downtown Waterfront ME

18. The Westin Portland Harborview

19. Residence Inn by Marriott Portland Downtown/Waterfront

20. Courtyard Portland Downtown/Waterfront

Compare popular hotels close to Maine Medical Center

Top Maine Medical Center Hotel Reviews

The Westin Portland Harborview

Quality Inn & Suites South Portland

Clarion Hotel Portland Airport ME

Holiday Inn Portland-By the Bay by IHG

Hilton Garden Inn Portland Downtown Waterfront

Moxy Portland Thompson's Point

Inn at St John Portland In-Town

Aloft by Marriott Portland Downtown Waterfront ME

West End Collection at 146 Pine

Frequently asked questions

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