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Find hotels near Calle 50, Panama City from NT$1,771

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Dec 22 - Dec 23
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Dec 23 - Dec 24
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Dec 26 - Dec 28
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Our top choices for Calle 50 hotels

Lobby
Hyatt Regency Panama City

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Campo Alegre, 1.2 km from Calle 50
10.0 out of 10, Exceptional, (127)
"Great hotel fair price"
United States
Santiago
The price is NT$4,947
NT$5,442 total
includes taxes & fees
Jan 3 - 2026/1/4
Hyatt Regency Panama City
Breakfast, lunch, dinner served; international cuisine
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco, 1 km from Calle 50
9.6 out of 10, Exceptional, (1120)
"The hotel is in a great location in Panama. Great amenities excellent breakfast."
United States
Maria
The price is NT$3,434
NT$3,777 total
includes taxes & fees
Jan 2 - 2026/1/3
Ramada Plaza by Wyndham Panama Punta Pacifica
Outdoor pool, sun loungers
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 0.7 km from Calle 50
9.0 out of 10, Wonderful, (4703)
"Awesome great place to stay "
United States
Herbert
The price is NT$3,452
NT$3,797 total
includes taxes & fees
Jan 12 - 2026/1/13
Hotel Riu Plaza Panama
Exterior
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco, 0.4 km from Calle 50
9.0 out of 10, Wonderful, (1006)
"Staff was very helpful. Great location."
United States
John
The price is NT$2,924
NT$3,217 total
includes taxes & fees
Jan 10 - 2026/1/11
Courtyard by Marriott Panama Multiplaza Mall
Exterior
Yoo Apartamento

Yoo Apartamento

Yoo Apartamento
3.0 star property
Bella Vista, 1.3 km from Calle 50
9.6 out of 10, Exceptional, (12)
"Great location"
United States
Jimmy Lee
The price is NT$2,777
NT$4,444 total
includes taxes & fees
Dec 24 - Dec 25
Yoo Apartamento
Couples treatment rooms, sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Campo Alegre, 1.1 km from Calle 50
9.4 out of 10, Exceptional, (1000)
"Great staff, super accommodating. Best place to stay in Panama!"
United States
Sebastian
The price is NT$6,331
NT$6,964 total
includes taxes & fees
Jan 14 - 2026/1/15
Bristol Panama, a Registry Collection Hotel
Lobby
The Executive Hotel

The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 1.2 km from Calle 50
9.2 out of 10, Wonderful, (1004)
"A nice hotel to stay great location"
United States
angela
The Executive Hotel
Terrace/patio
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 1.3 km from Calle 50
9.4 out of 10, Exceptional, (2137)
"Great location of the hotel with a lovely breakfast and friendly staff"
United States
fouad
The price is NT$4,990
NT$5,489 total
includes taxes & fees
Dec 29 - Dec 30
Plaza Paitilla Inn Hotel
Front of property - evening/night
Principe Hotel and Suites

Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
El Cangrejo, 0.9 km from Calle 50
9.0 out of 10, Wonderful, (1610)
"Friendly staff. "
United States
Thessely
The price is NT$1,610
NT$1,771 total
includes taxes & fees
Dec 24 - Dec 25
Principe Hotel and Suites
Exterior
Novotel Panama City

Novotel Panama City

Novotel Panama City
4.0 star property
El Cangrejo, 1.1 km from Calle 50
9.2 out of 10, Wonderful, (1036)
"Great service, big room, solid breakfasts.. all at good price."
Canada
Nicholas
The price is NT$3,352
NT$3,687 total
includes taxes & fees
Jan 10 - 2026/1/11
Novotel Panama City
View from property
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
Punta Paitilla, 0.9 km from Calle 50
9.0 out of 10, Wonderful, (1005)
"I loved my stay! "
United States
Jenniffer Gonzalez De La
The price is NT$5,095
NT$5,604 total
includes taxes & fees
Jan 13 - 2026/1/14
Las Americas Golden Tower Panama
Outdoor pool, free cabanas, sun loungers
Yoo Panama & Arts Tower

Yoo Panama & Arts Tower

Yoo Panama & Arts Tower
3.0 star property
Bella Vista, 1.3 km from Calle 50
9.4 out of 10, Exceptional, (50)
"Nice stay"
United States
ANGEL
Yoo Panama & Arts Tower
Restaurant
Gran Evenia Panama

Gran Evenia Panama

Gran Evenia Panama
4.5 star property
El Cangrejo, 1 km from Calle 50
9.2 out of 10, Wonderful, (195)
"The property was conveniently located near shops, restaurants and casinos. The food at breakfast was good. Although the pancakes could be better. "
United States
Nicole
Gran Evenia Panama
Outdoor pool
MARINN PLACE Financial District

MARINN PLACE Financial District

MARINN PLACE Financial District
3.5 star property
Campo Alegre, 1.2 km from Calle 50
9.2 out of 10, Wonderful, (299)
"Second stay, very nice"
Canada
Xiaozhi
The price is NT$3,535
NT$3,888 total
includes taxes & fees
Dec 23 - Dec 24
MARINN PLACE Financial District
Outdoor pool, sun loungers
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Obarrio, 0.6 km from Calle 50
8.8 out of 10, Excellent, (1001)
"Everything was clean and the staff was very cooperative."
United States
Deangelo
The price is NT$5,018
NT$5,520 total
includes taxes & fees
Jan 3 - 2026/1/4
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Exterior
TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro
3.5 star property
El Cangrejo, 1.4 km from Calle 50
9.2 out of 10, Wonderful, (1001)
"Great staff and the room was very clean. "
United States
JOHNNY
The price is NT$3,085
NT$3,394 total
includes taxes & fees
Dec 23 - Dec 24
TRYP by Wyndham Panamá Centro
Outdoor pool
Holiday Inn Panama Distrito Financiero by IHG

Holiday Inn Panama Distrito Financiero by IHG

Holiday Inn Panama Distrito Financiero by IHG
4.0 star property
Campo Alegre, 0.7 km from Calle 50
8.8 out of 10, Excellent, (1004)
"Clean room , friendly staff "
United States
Junique
The price is NT$2,525
NT$2,951 total
includes taxes & fees
Jan 16 - 2026/1/17
Holiday Inn Panama Distrito Financiero by IHG
Terrace/patio
Hostal Familiar Carmencita - Hostel

Hostal Familiar Carmencita - Hostel

Hostal Familiar Carmencita - Hostel
2.0 star property
Bella Vista, 1.1 km from Calle 50
9.2 out of 10, Wonderful, (9)
"The manager was very nice. Close to some good restaurants."
United States
Brooke
Hostal Familiar Carmencita - Hostel
Terrace/patio
Best Western Plus Panama Zen Hotel

Best Western Plus Panama Zen Hotel

Best Western Plus Panama Zen Hotel
4.0 star property
El Cangrejo, 1.1 km from Calle 50
9.0 out of 10, Wonderful, (984)
"Great view Great buffet Breakfast was excellent "
Canada
Robert
The price is NT$2,866
NT$3,153 total
includes taxes & fees
Dec 24 - Dec 25
Best Western Plus Panama Zen Hotel
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, sun loungers
Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
Punta Paitilla, 1 km from Calle 50
9.0 out of 10, Wonderful, (540)
"It's location is close to everything. "
United States
Sharon
The price is NT$5,070
NT$5,577 total
includes taxes & fees
Jan 2 - 2026/1/3
Residence Inn by Marriott Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Calle 50 Hotel Reviews

Megapolis Hotel Panamá

Megapolis Hotel Panamá

10/10 Excellent
"Excellent check-in. Great breakfast. Room was great "
Reginald 5-night trip
Posted 2 days ago
Megapolis Hotel Panamá

Hotels near other Calle 50 attractions

You can find Gucci at Luxury Avenue at Multiplaza Mall in Panama City. #LuxuryShopping #LifeatExpedia #PanamaCity
Photo by Fabiola Tile
Open Photo by Fabiola Tile

Multiplaza Pacific Mall

4.4/5 (1,590 reviews)
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
See properties
Nice building, highlight on Panama's skyline.
Photo by My World
Open Photo by My World

Soho City Center

You can browse for the perfect souvenirs at Soho City Center during your stay in Panama City. Discover the area's casinos, or seek out its local tours.
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Frequently asked questions

What's the area like around Calle 50?
Calle 50 is located in Panama City. This welcoming area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, check out the 469 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Calle 50?
Hotel Riu Plaza Panama is one of the top choices for your stay based on our traveler data, and this hotel offers 3 restaurants and free breakfast. It's located just a short 0.5 mi (0.7 km) from Calle 50. Other good options close by include Las Americas Golden Tower Panama and Megapolis Hotel Panamá.
How many hotels will I be able to find near Calle 50?
Expedia has 469 hotels and other accommodations within a mile from Calle 50.
If I need to cancel the hotel reservation for my stay near Calle 50, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of your booking. Add dates, click "Search", then use the "fully refundable" filter to view the best deals available near Calle 50.
Where can I learn more about changing or cancelling my trip in the area near Calle 50?
To find more details about updating your stay near Calle 50 or cancelling it, go to https://www.expedia.com/service/.
What can I see and do near Calle 50?
You'll want to browse the collections at Interoceanic Canal Museum, Biomuseo, and Colonial Religious Art Museum. Iglesia del Carmen, Panama Viejo, and Panama Canal Railway are notable landmarks to explore if you're in the area. You can catch a show at National Theater, Theater Circle, and Anita Villalaz Theater.
How can I get to Calle 50?
Local metro stations include Iglesia del Carmen Station and Vía Argentina. If you'd like to explore around the surrounding area, you may want a car rental for your journey.