Defiance 2 Stars Hotels
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Compare Defiance 2 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Our top choices for Defiance 2-star hotels

Relax Inn Saint Charles
Relax Inn Saint Charles
6.4 out of 10, (1009)
The price is NT$1,925
NT$2,213 total
includes taxes & fees
Sep 9 - Sep 10

Days Inn and Suites by Wyndham St. Louis/Westport Plaza
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
4.6 out of 10, (1009)
The price is NT$2,078
NT$2,410 total
includes taxes & fees
Sep 15 - Sep 16

Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology Drive
8.8 out of 10, Excellent, (1007)
The price is NT$2,723
NT$3,212 total
includes taxes & fees
Sep 14 - Sep 15

Best Western Plus St. Louis West-Westport
Best Western Plus St. Louis West-Westport
8.0 out of 10, Very Good, (1002)
The price is NT$2,586
NT$2,999 total
includes taxes & fees
Sep 14 - Sep 15

Country Inn & Suites by Radisson, St. Charles Historic District
Country Inn & Suites by Radisson, St. Charles Historic District
9.4 out of 10, Exceptional, (1013)
The price is NT$3,481
NT$4,001 total
includes taxes & fees
Sep 11 - Sep 12

Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. Peters
8.0 out of 10, Very Good, (1003)
The price is NT$2,498
NT$2,871 total
includes taxes & fees
Sep 28 - Sep 29

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
5.8 out of 10, (1002)
The price is NT$2,139
NT$2,480 total
includes taxes & fees
Sep 9 - Sep 10

Baymont by Wyndham St. Charles
Baymont by Wyndham St. Charles
8.0 out of 10, Very Good, (1001)
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Explore similar 3-star hotels
Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Defiance.

Hollywood Casino & Hotel St. Louis
777 Casino Center Drive, Maryland Heights, MO
The price is NT$5,501 per night from Sep 26 to Sep 27
NT$5,501
NT$6,869 total
Sep 26 - Sep 27
includes taxes & fees
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Defiance
Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighboring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

Top Defiance Hotel Reviews
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Defiance Hotels by Star Rating
Stay near popular Defiance attractions
- Hotels near August A. Busch Memorial Conservation Area
- Hotels near Chandler Hill Vineyards
- Hotels near Historic Daniel Boone Home and Heritage Center
- Hotels near Sugar Creek Winery
- Hotels near Yellow Farmhouse Winery
- Hotels near Broemmelsiek Park
- Hotels near Six Flags St. Louis
- Hotels near Mississippi River
- Hotels near Hollywood Casino Amphitheatre
- Hotels near Ameristar Casino St. Charles
- Hotels near Westport Plaza
- Hotels near Hollywood Casino
- Hotels near St Charles Convention Center
- Hotels near Route 66 State Park
- Hotels near Magic House - St. Louis Children's Museum
- Hotels near Historic Main Street
- Hotels near Missouri River
- Hotels near Purina Farms
- Hotels near Lindenwood University
- Hotels near St. Louis Premium Outlets
Explore more hotels
- Hilton St. Louis Frontenac
- Best Western Plus St. Louis West-Westport
- Hyatt Place St. Louis/Chesterfield
- Sonesta ES Suites St. Louis - Chesterfield
- Relax Inn Saint Charles
- Days Inn and Suites by Wyndham St. Louis/Westport Plaza
- Holiday Inn St. Louis - Creve Coeur by IHG
- Marriott St. Louis West
- Courtyard by Marriott St Louis Westport Plaza
- Crowne Plaza St. Louis Airport by IHG
- Best Western Plus The Charles Hotel
- Hampton Inn St. Charles St. Peters
- Drury Inn & Suites Southwest St. Louis
- DoubleTree by Hilton St. Louis - Westport
- Drury Inn & Suites St. Louis St. Peters
- Comfort Inn St. Louis - Westport Event Center
- Elimwood Hotel, a Ramada by Wyndham
- Comfort Suites St Charles - St Louis
- Country Inn & Suites by Radisson, St. Charles Historic District
- Sonesta Simply Suites St Louis Earth City
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