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Find hotels in Defiance, MO from NT$2,136

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Oct 17 - Oct 18
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Oct 18 - Oct 19
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Oct 17 - Oct 19
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Oct 24 - Oct 26

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Compare 844 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Lobby sitting area
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
8.2 out of 10, Very Good, (1027)
"Clean room and staff was great "
Beth
The price is NT$2,597
NT$3,000 total
includes taxes & fees
Nov 9 - Nov 10
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Ballroom
The Wildwood Hotel
The Wildwood Hotel
3.5 star property
9.2 out of 10, Wonderful, (1596)
"We enjoyed our stay!"
Michael
The Wildwood Hotel
Front of property
Sonesta ES Suites St. Louis - Chesterfield
Sonesta ES Suites St. Louis - Chesterfield
3.0 star property
8.0 out of 10, Very Good, (1008)
"This was a very nice place to stay. Centrally located, very clean and quiet with a great breakfast!"
Kirsti
The price is NT$2,659
NT$3,084 total
includes taxes & fees
Oct 30 - Oct 31
Sonesta ES Suites St. Louis - Chesterfield
Front of property
Super 8 by Wyndham Eureka/Six Flags Nearby
Super 8 by Wyndham Eureka/Six Flags Nearby
2.0 star property
7.0 out of 10, Good, (1010)
"Clean rooms fully stocked room with towels "
Paul
The price is NT$1,833
NT$2,136 total
includes taxes & fees
Oct 30 - Oct 31
Super 8 by Wyndham Eureka/Six Flags Nearby
Property amenity
Baymont by Wyndham Warrenton
Baymont by Wyndham Warrenton
2.5 star property
7.4 out of 10, Good, (1007)
"Very friendly staff. Nice place to stay"
Bobby
The price is NT$2,619
NT$3,005 total
includes taxes & fees
Nov 2 - Nov 3
Baymont by Wyndham Warrenton
Lobby
Best Western Plus St. Louis West-Westport
Best Western Plus St. Louis West-Westport
2.5 star property
8.0 out of 10, Very Good, (1013)
"It was a very nice place"
Jill
The price is NT$2,647
NT$3,070 total
includes taxes & fees
Nov 17 - Nov 18
Best Western Plus St. Louis West-Westport
Exterior
Holiday Inn Express & Suites Wentzville St Louis West by IHG
Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
9.4 out of 10, Exceptional, (807)
"The breakfast was great… clean and well stocked food area and dining tables. Room was clean and bed comfortable. Convenient to the highway and gas and shops."
Mary
The price is NT$4,135
NT$4,927 total
includes taxes & fees
Nov 16 - Nov 17
Holiday Inn Express & Suites Wentzville St Louis West by IHG
Lobby
Days Inn by Wyndham St Peters/St Charles
Days Inn by Wyndham St Peters/St Charles
2.0 star property
6.4 out of 10, (997)
"The carpet felt a little damp but aside from that the room was clean and comfortable. "
Nikki
The price is NT$2,057
NT$2,364 total
includes taxes & fees
Nov 17 - Nov 18
Days Inn by Wyndham St Peters/St Charles
Lobby
Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
8.8 out of 10, Excellent, (1013)
"Great hotel! "
Jeffrey Frank
The price is NT$2,668
NT$3,147 total
includes taxes & fees
Oct 27 - Oct 28
Sleep Inn & Suites O'Fallon MO - Technology Drive
Front of property - evening/night
Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
3.5 star property
8.4 out of 10, Very Good, (2169)
"Always our favorite place to stay!"
Julie
The price is NT$2,857
NT$3,776 total
includes taxes & fees
Oct 26 - Oct 27
Hollywood Casino & Hotel St. Louis
1 bedroom, Egyptian cotton sheets, premium bedding, pillowtop beds
Best Western Plus Washington Hotel
Best Western Plus Washington Hotel
2.5 star property
9.0 out of 10, Wonderful, (611)
" Great value. Very friendly staff and comfortable rooms."
Robert
The price is NT$3,942
NT$4,488 total
includes taxes & fees
Oct 20 - Oct 21
Best Western Plus Washington Hotel
Lobby
AC Hotel by Marriott St. Louis Chesterfield
AC Hotel by Marriott St. Louis Chesterfield
3.5 star property
9.2 out of 10, Wonderful, (210)
"Loved my stay here "
nakia
The price is NT$4,645
NT$5,387 total
includes taxes & fees
Oct 30 - Oct 31
AC Hotel by Marriott St. Louis Chesterfield
Exterior
Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. Peters
2.5 star property
8.0 out of 10, Very Good, (1015)
"Excellent hotel. Excellent location, friendly staff, and delicious breakfast."
Jean ss
The price is NT$2,863
NT$3,291 total
includes taxes & fees
Nov 17 - Nov 18
Hampton Inn St. Charles St. Peters
Terrace/patio
Elimwood Hotel, a Ramada by Wyndham
Elimwood Hotel, a Ramada by Wyndham
3.0 star property
7.4 out of 10, Good, (1010)
"Clean nice room, staff was all very friendly & helpful, exceptionally so. "
Jeanne
The price is NT$2,668
NT$3,095 total
includes taxes & fees
Oct 26 - Oct 27
Elimwood Hotel, a Ramada by Wyndham
Exterior
Holiday Inn Express St. Louis West - O'Fallon by IHG
Holiday Inn Express St. Louis West - O'Fallon by IHG
2.5 star property
8.6 out of 10, Excellent, (802)
"Clean, well maintained hotel. Friendly staff, great breakfast. Close to shopping and restaurants."
Theresa
The price is NT$2,903
NT$3,424 total
includes taxes & fees
Oct 26 - Oct 27
Holiday Inn Express St. Louis West - O'Fallon by IHG
Lobby
Drury Plaza Hotel St. Louis St. Charles
Drury Plaza Hotel St. Louis St. Charles
3.0 star property
9.6 out of 10, Exceptional, (1010)
"Great staff and great amenities!"
Alicia
The price is NT$3,361
NT$3,896 total
includes taxes & fees
Oct 26 - Oct 27
Drury Plaza Hotel St. Louis St. Charles
Premium bedding, desk, iron/ironing board, free cribs/infant beds
Super 8 by Wyndham St Charles
Super 8 by Wyndham St Charles
2.0 star property
8.0 out of 10, Very Good, (1013)
"Clean room and comfortable bed I would stay again. "
janeice
The price is NT$2,312
NT$2,657 total
includes taxes & fees
Oct 28 - Oct 29
Super 8 by Wyndham St Charles
Exterior
Holiday Inn Express & Suites St. Louis West - Fenton by IHG
Holiday Inn Express & Suites St. Louis West - Fenton by IHG
3.0 star property
8.8 out of 10, Excellent, (1003)
"Clean room great staff"
Jayson
The price is NT$3,154
NT$3,642 total
includes taxes & fees
Oct 26 - Oct 27
Holiday Inn Express & Suites St. Louis West - Fenton by IHG
Lobby
Super 8 by Wyndham Union
Super 8 by Wyndham Union
2.0 star property
8.2 out of 10, Very Good, (621)
"Clean room great staff"
Jayson
The price is NT$2,371
NT$2,619 total
includes taxes & fees
Nov 12 - Nov 13
Super 8 by Wyndham Union
In-room safe, desk, laptop workspace, blackout drapes
Super 8 by Wyndham Warrenton
Super 8 by Wyndham Warrenton
2.0 star property
7.4 out of 10, Good, (603)
"I have stayed several times at this hotel, it is always very clean, the staff are super nice and very convenient to I-70; would recommend this hotel and I will definitely stay there again."
Kimberly
The price is NT$2,005
NT$2,300 total
includes taxes & fees
Nov 2 - Nov 3
Super 8 by Wyndham Warrenton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri

August A. Busch Memorial Conservation Area

Explore the great outdoors at August A. Busch Memorial Conservation Area, a lovely green space in Defiance. While in this family-friendly area, you can savor the top-notch restaurants.
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Missouri wineries have some of the most superb wine we've ever tasted! We recommend sipping on some chambourcin while basking in the sunshine.
Photo by Pages of Travel
Open Photo by Pages of Travel

Chandler Hill Vineyards

You can enjoy a tasting or tour at Chandler Hill Vineyards during your travels to Defiance. While in this romantic area, you can savor the top-notch restaurants.
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Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighboring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance

Top Defiance Hotel Reviews

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66

10/10 Excellent
"I didn’t eat there. Bed was too soft. "
Eiblis 1-night trip
Posted 3 days ago
Wingate by Wyndham St. Louis/Fenton Route 66

More cheap stays in Defiance

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

1310 Bass Pro Drive, St. Charles, MO
The price is NT$2,139 per night from Oct 21 to Oct 22
NT$2,139
NT$2,479 total
Oct 21 - Oct 22
includes taxes & fees
5.6/10 (1,012 reviews)

Frequently asked questions

What's the best place to stay in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, located 17.9 mi (28.8 km) from the heart of Defiance, is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are Hollywood Casino & Hotel St. Louis and Courtyard by Marriott St Louis Creve Coeur. See all available top hotels, or vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
Where can I learn more about changing or cancelling my trip to Defiance?
For more information about changing or cancelling your trip to Defiance, head over to our customer service page.
Where is the best hotel to stay with easy access to August A. Busch Memorial Conservation Area?
Sleep Inn & Suites O'Fallon MO - Technology Drive is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 2.6 mi (4.3 km) from August A. Busch Memorial Conservation Area. Other good options within a few miles include Hilton Garden Inn St. Louis/O'Fallon MO and Holiday Inn Express St. Louis West - O'Fallon, an IHG Hotel.
What about the best place to stay near Chandler Hill Vineyards?
One of the top choices for your stay is The Wildwood Hotel, located 10 mi (16.1 km) from Chandler Hill Vineyards, and this 3.5-star hotel offers free breakfast and an indoor pool.
What are some accommodations with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Features an indoor pool, an outdoor pool, and buffet. Drury Plaza Hotel St. Louis Creve Coeur and Hampton Inn St. Charles St. Peters are two additional hotels that offer an onsite pool. View all hotels with pools in Defiance.
What's the best place to stay near Lambert-St. Louis International Airport (STL)?
Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.
What's it like to stay in Defiance?
Visitors can enjoy all that Defiance has to offer including the wineries and parks. Top sights in the area include St. Louis Union Station, Busch Stadium, and Gateway Arch. In Defiance, there are 20 hotels and other accommodations to choose from. Find out more about Defiance.
What is there to see in Defiance?
Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River, and Matson Hill Park Trailhead. A couple of additional sights to add to your agenda are Yellow Farmhouse Winery and Chandler Hill Vineyards. Check out what more to see and do in Expedia's Defiance guide.
What's the seasonal weather like in Defiance?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.

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