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Oct 16 - Oct 18
In two weeks
Oct 23 - Oct 25

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Our top choices for North Clayton hotels

A modern lounge area with a stone fireplace, comfortable seating, and a bar in the background.

1. Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3.0 star property
North Clayton
8.8 out of 10, Excellent, (1,002 reviews)
"Great location - staff was awesome!"
United States
Kevin
The price is NT$4,315
NT$5,080 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
A modern hotel lobby with a reception desk, seating area, and a refreshment bar.

2. SpringHill Suites St. Louis Brentwood

SpringHill Suites St. Louis Brentwood
3.0 star property
3.6 km from North Clayton
9.0 out of 10, Wonderful, (1,003 reviews)
"Staff was very friendly and rooms were clean."
United States
Aaron
The price is NT$3,994
NT$4,712 total
includes taxes & fees
Nov 1 - Nov 2
SpringHill Suites St. Louis Brentwood
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

3. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
3.1 km from North Clayton
9.6 out of 10, Exceptional, (1,001 reviews)
"Excellent place to stay. Beautiful hotel, amazing friendly and attentive staff. Would highly recommend!!"
United States
Janell
The price is NT$4,182
NT$4,966 total
includes taxes & fees
Nov 1 - Nov 2
Drury Plaza Hotel St. Louis Brentwood
An outdoor patio with a fire pit, seating, and a building in the background.

4. Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
3 km from North Clayton
9.4 out of 10, Exceptional, (908 reviews)
"Everything is great here. Stay here every time I’m in St. Louis, they are accommodating, nice and it’s very clean. I highly recommend it."
United States
Wendy
The price is NT$3,772
NT$4,601 total
includes taxes & fees
Oct 18 - Oct 19
Courtyard by Marriott St. Louis Brentwood
The Clayton Plaza Hotel sign with a stone wall and plants in front.

5. Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
0.8 km from North Clayton
9.0 out of 10, Wonderful, (3,472 reviews)
"Great location, lots of things to do in the area and the staff was amazing!"
United States
Daniele
The price is NT$2,843
NT$3,319 total
includes taxes & fees
Oct 25 - Oct 26
Clayton Plaza Hotel & Extended Stay
A courtyard with outdoor seating, a central fountain, and a view of a tower.

6. The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
2.7 km from North Clayton
9.4 out of 10, Exceptional, (701 reviews)
"Beautiful hotel and very clean. We had a wonderful stay!"
United States
Rosalyn
The price is NT$4,860
NT$5,589 total
includes taxes & fees
Nov 1 - Nov 2
The Knight Center at Washington University
A rooftop restaurant with round tables, chairs, and a view of the city.

7. Moonrise Hotel

Moonrise Hotel
4.0 star property
3.7 km from North Clayton
9.0 out of 10, Wonderful, (2,038 reviews)
"Great location"
United States
Katherine
The price is NT$5,146
NT$6,120 total
includes taxes & fees
Nov 3 - Nov 4
Moonrise Hotel
A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

8. Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
9 km from North Clayton
9.2 out of 10, Wonderful, (1,003 reviews)
"This is a great place to stay at !"
United States
Daisy
The price is NT$3,512
NT$4,354 total
includes taxes & fees
Oct 18 - Oct 19
Hyatt Select St. Louis Airport
A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

9. Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
3.0 star property
9.7 km from North Clayton
9.2 out of 10, Wonderful, (1,708 reviews)
"Staff was wonderful..great location with BBQ restaurant next door"
United States
Mary
The price is NT$3,090
NT$3,670 total
includes taxes & fees
Oct 18 - Oct 19
Wingate by Wyndham St. Louis Airport
An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

10. Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport
2.5 star property
9.2 km from North Clayton
9.0 out of 10, Wonderful, (238 reviews)
"Friendly staff, convenient location, quiet room, comfortable bed."
United States
Leia
The price is NT$4,112
NT$4,948 total
includes taxes & fees
Oct 29 - Oct 30
Hampton Inn By Hilton St Louis Airport
An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

11. Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
Dogtown, 5.9 km from North Clayton
9.4 out of 10, Exceptional, (1,004 reviews)
"It was clean, free parking available and great location for our purpose"
United States
Debbie
The price is NT$4,424
NT$5,218 total
includes taxes & fees
Nov 9 - Nov 10
Hampton Inn & Suites St. Louis at Forest Park
A cozy lounge area with leather sofas, a fireplace, and a bar counter.

12. The Cheshire

The Cheshire
4.0 star property
3.8 km from North Clayton
8.8 out of 10, Excellent, (1,003 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
The price is NT$4,738
NT$5,626 total
includes taxes & fees
Oct 18 - Oct 19
The Cheshire
A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

13. Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport
3.0 star property
9.4 km from North Clayton
9.2 out of 10, Wonderful, (1,436 reviews)
"Excellent place to stay, highly recommend."
United States
Ethan
The price is NT$3,671
NT$4,344 total
includes taxes & fees
Oct 18 - Oct 19
Drury Inn & Suites St. Louis Airport
An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

14. Home2 Suites by Hilton St. Louis/Forest Park

Home2 Suites by Hilton St. Louis/Forest Park
3.0 star property
The Grove, 7.5 km from North Clayton
8.6 out of 10, Excellent, (1,006 reviews)
"Staff was nice and helpful food was great and room was amazing!!! "
United States
paullita jeanne
The price is NT$4,964
NT$5,804 total
includes taxes & fees
Oct 18 - Oct 19
Home2 Suites by Hilton St. Louis/Forest Park
A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

15. Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
9.7 km from North Clayton
9.2 out of 10, Wonderful, (3,291 reviews)
"Excellent stay"
United States
Murphy
The price is NT$2,873
NT$3,411 total
includes taxes & fees
Oct 18 - Oct 19
Pear Tree Inn St. Louis Airport
A buffet with fruits, pastries, and beverages.

16. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
8.6 km from North Clayton
8.4 out of 10, Very good, (1,169 reviews)
"Great stay"
United States
Anthony
The price is NT$3,772
NT$4,413 total
includes taxes & fees
Oct 29 - Oct 30
Renaissance St. Louis Airport Hotel
A bar area with a long counter displaying numerous bottles of alcohol and several empty wine glasses lined up.

17. Holiday Inn St Louis SW - Route 66 by IHG

Holiday Inn St Louis SW - Route 66 by IHG
3.0 star property
12.4 km from North Clayton
9.2 out of 10, Wonderful, (589 reviews)
"I like the hotel completely. The cleanliness and staff and restaurant were amazing"
United States
Eric
The price is NT$3,767
NT$4,481 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn St Louis SW - Route 66 by IHG
A modern lounge area with a stone fireplace, a blue sofa, and a small table.

18. Fairfield Inn & Suites St Louis Westport

Fairfield Inn & Suites St Louis Westport
3.0 star property
10 km from North Clayton
9.2 out of 10, Wonderful, (875 reviews)
"The staff was very friendly and attentive."
United States
Alan
The price is NT$4,186
NT$4,898 total
includes taxes & fees
Oct 18 - Oct 19
Fairfield Inn & Suites St Louis Westport
A courtyard with outdoor seating, a fire pit, and a well-maintained garden.

19. Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur
3.0 star property
Creve Coeur, 9 km from North Clayton
8.6 out of 10, Excellent, (1,002 reviews)
"Nice clean property Friendly helpful staff"
United States
Scott
The price is NT$3,624
NT$4,213 total
includes taxes & fees
Oct 18 - Oct 19
Courtyard by Marriott St Louis Creve Coeur
A modern building with the name "La Quinta" prominently displayed.

20. La Quinta Inn & Suites by Wyndham St Louis Route 66

La Quinta Inn & Suites by Wyndham St Louis Route 66
3.0 star property
12.3 km from North Clayton
8.4 out of 10, Very good, (1,008 reviews)
"Great place!"
United States
Edward
The price is NT$3,202
NT$3,722 total
includes taxes & fees
Nov 1 - Nov 2
La Quinta Inn & Suites by Wyndham St Louis Route 66
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Hotels recommended for families in North Clayton

A modern lounge area with a stone fireplace, comfortable seating, and a bar in the background.

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3.0 star property
Clayton
8.8 out of 10, Excellent, (1,002)
The price is NT$4,315
NT$5,080 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Where to stay in North Clayton

Find the best North Clayton areas and neighborhoods for the activities you enjoy most.
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Top North Clayton Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"The Drury is by far the best place to stay hands down!! The care they have for their customers is top notch…. You feel like family!! Awesome experience!!"
Brian 2-night trip
Posted less than an hour ago
Drury Plaza Hotel St. Louis Union Station

Frequently asked questions

What is North Clayton like?
Travelers to St. Louis's North Clayton neighborhood will be sure to enjoy a stay in this neighborhood.
What's the best accommodation in North Clayton?
Based on our traveler data, Hampton Inn & Suites Clayton/St. Louis-Galleria Area is one of the top choices for your stay in North Clayton. This hotel offers free breakfast and an indoor pool.
How many hotels can I expect to find in the North Clayton area?
If you're searching for places to stay in St. Louis, choose from one of Expedia's 11 hotels and other accommodations in North Clayton.
If I need to cancel my hotel reservation in North Clayton, will I receive a refund?
Yes, most hotel reservations are refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to view the best options available in North Clayton.
Where can I learn more about changing or cancelling my trip to North Clayton?
For more information about updating your trip to North Clayton or cancelling it, click here.
What is there to do in this St. Louis neighborhood?
St. Louis Zoo, Shaw Park Tennis Center, and Saint Louis Galleria Mall are just a few of the places to visit in and around North Clayton. While you're out sightseeing, Heman Park Tennis Center and Tao Tennis Center are a couple of additional sights to visit in St. Louis.

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