The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

louis

NT$3,895 total

includes taxes & fees

Nov 24 - Nov 25

A golf course with a pond, a clubhouse, and a hilly backdrop.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

A Candy

NT$5,838 total

includes taxes & fees

Nov 18 - Nov 19

A modern infinity pool with a view of mountains and a sunset.

3. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Nabeel

NT$4,915 total

includes taxes & fees

Dec 14 - Dec 15

A hotel room with two beds, a TV, a desk, a chair, and a view of palm trees.

4. Hyatt Place Phoenix/Mesa

17.8 km from Mayo Clinic Scottsdale

Laura

NT$3,793 total

includes taxes & fees

Nov 24 - Nov 25

An outdoor patio with two sofas facing a stone fire pit, under a pergola with string lights.

5. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Jillian Louise

NT$5,107 total

includes taxes & fees

Nov 28 - Nov 29

A modern lobby with a stone fireplace, comfortable seating, and a television.

6. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

LAURA

NT$3,912 total

includes taxes & fees

Nov 29 - Nov 30

A breakfast bar with a coffee station, waffle maker, and various food containers.

7. Sonesta ES Suites Scottsdale Paradise Valley

14 km from Mayo Clinic Scottsdale

James

NT$3,858 total

includes taxes & fees

Nov 23 - Nov 24

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

8. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

Ryan

NT$3,225 total

includes taxes & fees

Dec 14 - Dec 15

A modern building with a glass facade, a paved walkway, and parked cars.

9. Element by Marriott Scottsdale at SkySong

18.4 km from Mayo Clinic Scottsdale

Darryl

NT$3,783 total

includes taxes & fees

Nov 22 - Nov 23

A hotel with a clear sky, a sign for 'Spark by Hilton', and a well-maintained lawn.

10. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Herbert M Beatty

NT$3,046 total

includes taxes & fees

Nov 22 - Nov 23

A modern hotel with a brick facade, large windows, and a covered entrance area.

11. Springhill Suites Phoenix Scottsdale Marriott

18.2 km from Mayo Clinic Scottsdale

Anna

NT$4,100 total

includes taxes & fees

Nov 22 - Nov 23

A modern outdoor patio with a fire pit, seating, and a cactus in a landscaped garden.

12. Courtyard Scottsdale Salt River

12.2 km from Mayo Clinic Scottsdale

Karl

NT$4,682 total

includes taxes & fees

Nov 28 - Nov 29

A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

13. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Saad

NT$3,708 total

includes taxes & fees

Dec 14 - Dec 15

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

14. Hyatt Place Scottsdale - North

14.1 km from Mayo Clinic Scottsdale

Ted

NT$4,685 total

includes taxes & fees

Dec 14 - Dec 15

A golf course with a clear view of mountains in the background.

15. Hampton Inn & Suites Scottsdale at Talking Stick

9.1 km from Mayo Clinic Scottsdale

Kevin Boland- Martin

NT$4,427 total

includes taxes & fees

Nov 22 - Nov 23

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

16. Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Katherine

NT$5,131 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor patio area with tables and chairs, surrounded by potted plants and palm trees.

17. Papago Scottsdale by Reside, Trademark Collection by Wyndham

18.4 km from Mayo Clinic Scottsdale

Allan

NT$3,717 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor seating area with a fire feature, surrounded by blue chairs and a stone fire pit.

18. Delta Hotels by Marriott Phoenix Mesa

18.7 km from Mayo Clinic Scottsdale

Joshua

NT$4,018 total

includes taxes & fees

Nov 22 - Nov 23

A spacious lobby with a large seating area, a reception desk, and artwork on the walls.

19. Best Western Plus Scottsdale Thunderbird Suites

Thunderbird Industrial Airpark, 12.1 km from Mayo Clinic Scottsdale

Irene

NT$3,798 total

includes taxes & fees

Dec 14 - Dec 15

An outdoor dining area with tables and chairs, surrounded by trees and a view of a mountain.

20. Mountain Shadows Resort Scottsdale

17 km from Mayo Clinic Scottsdale

karen

NT$9,037 total

includes taxes & fees

Nov 24 - Nov 25

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	3.0 star property	8.4 Very good 1,087 reviews	View
Inn at Eagle Mountain	3.5 star property	9.0 Wonderful 1,041 reviews	View
Talking Stick Resort	4.0 star property	9.4 Exceptional 5,196 reviews	View
Hyatt Place Phoenix/Mesa	3.0 star property	9.2 Wonderful 2,002 reviews	View
Home2 Suites by Hilton Mesa Longbow, AZ	4.0 star property	9.6 Exceptional 931 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

A bedroom with a bed, a lamp, an air conditioning unit, and curtains.

Starlite Motel

Central Mesa

10/10 Excellent

Virginia

Mountain Shadows Resort Scottsdale

Paradise Valley

10/10 Excellent

Rachael

Hyatt House North Scottsdale

Scottsdale

10/10 Excellent

Alexander

Home2 Suites by Hilton Mesa Longbow, AZ

Falcon Field Area

10/10 Excellent

Alvin

A rooftop terrace with outdoor seating, a fire feature, and a mountain view.

Canopy by Hilton Scottsdale Old Town

Old Town

10/10 Excellent

Shahar

An outdoor patio area with a central fire feature, seating arrangements, and a covered walkway.

Residence Inn Scottsdale Salt River

Scottsdale

10/10 Excellent

Maria Robelle

A modern interior with a staircase, a dining area, and a balcony with a tripod.

Hotel Valley Ho

Old Town

10/10 Excellent

Andrew T

Courtyard Scottsdale Salt River

Scottsdale

10/10 Excellent

Monica

Hyatt Place Scottsdale - North

Scottsdale

10/10 Excellent

Yoana

Comfort Suites Scottsdale Talking Stick Entertainment District

Scottsdale

10/10 Excellent

Darla

A poolside area with a fire feature, seating, and a view of the pool.

Fairfield Inn & Suites by Marriott Tempe

Tempe

10/10 Excellent

I planned a weekend staycation and just wanted a quiet weekend. The price was shockingly great for the location and quality, the reviews and photos sold me and it didn't disappoint. The pool is beautiful. The restaurant in the hotel is pretty good as well, we ordered the Cowboy Burger and the Surf n Turf Burger and both were very good. The hotel was clean, the location is convenient being by Tempe Marketplace so there's plenty to eat and do, and it was overall a great option. I'd absolutely stay...

Krimsun

Inn at Eagle Mountain

Eagle Mountain

10/10 Excellent

carla

A modern kitchen with a microwave, refrigerator, and a coffee maker. There is a dining area with a table and chairs.

Home2 Suites by Hilton Scottsdale Salt River

Scottsdale

10/10 Excellent

Tracy

A resort with multiple buildings, a large pool area, and surrounding mountains.

ADERO Scottsdale Resort, Autograph Collection

Scottsdale

10/10 Excellent

LaKoya

A swimming pool with people on inflatable floats, lounge chairs, and umbrellas in the background.

Wekopa Casino Resort

Fort McDowell

10/10 Excellent

Helen

A building with a white brick exterior, large windows, and a variety of cacti and succulents in the surrounding garden area.

Senna House Hotel Scottsdale, Curio Collection by Hilton

Old Town

10/10 Excellent

Vladimira

Frequently Asked Questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,667

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Treat yourself

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. Talking Stick Resort

4. Hyatt Place Phoenix/Mesa

5. Home2 Suites by Hilton Mesa Longbow, AZ

6. Comfort Suites Scottsdale Talking Stick Entertainment District

7. Sonesta ES Suites Scottsdale Paradise Valley

8. Aiden by Best Western Scottsdale North

9. Element by Marriott Scottsdale at SkySong

10. Spark by Hilton Fountain Hills Scottsdale

11. Springhill Suites Phoenix Scottsdale Marriott

12. Courtyard Scottsdale Salt River

13. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

14. Hyatt Place Scottsdale - North

15. Hampton Inn & Suites Scottsdale at Talking Stick

16. Hyatt House North Scottsdale

17. Papago Scottsdale by Reside, Trademark Collection by Wyndham

18. Delta Hotels by Marriott Phoenix Mesa

19. Best Western Plus Scottsdale Thunderbird Suites

20. Mountain Shadows Resort Scottsdale

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Starlite Motel

10/10 Excellent

Frequently Asked Questions

What's the area like around Mayo Clinic Scottsdale?

What's the best place to stay near Mayo Clinic Scottsdale?

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

What can I see and do near Mayo Clinic Scottsdale?

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