The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

Michael

NT$2,591

NT$2,953 total

includes taxes & fees

Oct 1 - Oct 2

A cluster of modern, multi-story buildings with a river in the foreground.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

A golf course with a pond, a clubhouse, and a hilly backdrop.

A dining area with a glass table, wooden chairs, and potted plants.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Andrei

NT$3,579

NT$4,086 total

includes taxes & fees

Sep 29 - Sep 30

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.

A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Cathleen

NT$2,591

NT$2,953 total

includes taxes & fees

Sep 30 - Oct 1

A hotel room with two beds, a TV, a desk, and a window with a view.

A pool area with a clear blue pool, lounge chairs, and a multi-story building with balconies.

A hotel room with two beds, a desk, a TV, and a balcony with a view.

A modern office space with multiple desks, chairs, and a meeting area.

4. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Peyton

NT$2,448

NT$2,795 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

A modern hotel lobby with a central bar area, seating arrangements, and a clean, contemporary design.

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

5. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

William

NT$3,047

NT$3,474 total

includes taxes & fees

Sep 30 - Oct 1

A wooden door with a glass panel, a doormat, and a small window above it.

A modern kitchen with white cabinets, a built-in oven, and a large window.

A bedroom with a desk, a bed, a ceiling fan, and a window with blinds.

6. Close to Hiking! Family-friendly Mesa Retreat

13.6 km from Mayo Clinic Scottsdale

NT$5,716

NT$24,864 total

includes taxes & fees

Sep 29 - Sep 30

A spacious living area with a kitchen, modern furniture, and a fireplace.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

A spacious lobby with a high ceiling, modern chandeliers, a fire feature, and a large TV screen.

7. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

NT$2,985

NT$3,408 total

includes taxes & fees

Sep 29 - Sep 30

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A dining area with a large table set for six, surrounded by chairs, with a view of cacti and a stone wall outside.

A lounge area with a grand piano, blue seating, and a stone wall.

A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

8. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

Darrick

NT$3,488

NT$5,847 total

includes taxes & fees

Sep 29 - Sep 30

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

A bar area with a bar counter, multiple chairs, and a sofa.

A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

9. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

cody

NT$2,734

NT$3,116 total

includes taxes & fees

Sep 29 - Sep 30

A modern infinity pool with a view of mountains and a sunset.

A restaurant with high tables and booths, floral wall decorations, and a view of the mountains.

A modern bar area with a unique ceiling design, a bar counter with multiple screens, and a patterned carpet.

A poolside lounge with a view of a hotel building, a TV, and a bar area with a bottle of champagne.

10. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Meghan Rebbecca

NT$6,744

NT$8,595 total

includes taxes & fees

Oct 1 - Oct 2

An outdoor dining table set with chairs, string lights, and a sunset view.

A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.

A multi-story hotel with a prominent entrance, large windows, and a well-lit facade.

A modern living room with a sectional sofa, orange ottomans, a dining area, and a kitchen with a stone accent wall.

11. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Damon

NT$4,430

NT$5,062 total

includes taxes & fees

Oct 1 - Oct 2

A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.

A hotel breakfast area with a self-serve station, seating, and a trash bin.

A hotel room with a desk, chair, television, lamp, and a framed artwork on the wall.

A hotel gym with dumbbells on racks, a bench, and a mirror.

12. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Melanie

NT$2,763

NT$3,149 total

includes taxes & fees

Oct 26 - Oct 27

A resort with multiple buildings, a large pool area, and surrounding mountains.

A dining area with a table and chairs, a view of a cityscape, and decorative wall panels.

An outdoor wedding reception with round tables set with white chairs, floral centerpieces, and a view of the city in the background.

A dining area with a table set for six, overlooking a scenic landscape.

13. ADERO Scottsdale Resort, Autograph Collection

3.6 km from Mayo Clinic Scottsdale

Karen

NT$7,367

NT$9,680 total

includes taxes & fees

Oct 1 - Oct 2

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

14. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Colleen

NT$3,851

NT$4,390 total

includes taxes & fees

Sep 30 - Oct 1

A hotel dining area with a table and chairs, patterned curtains, and a view through large windows.

A building entrance with a stone facade, large glass doors, and potted plants.

A golf course with sand bunkers, a flagstick, and mountains in the background.

A hotel room with a large window, a desk, a bed, a TV, and a chair.

15. Hampton Inn & Suites Scottsdale at Talking Stick

9.1 km from Mayo Clinic Scottsdale

Mark

NT$3,880

NT$4,424 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor patio area with round tables and chairs, a pool in the background, and a covered seating area.

A hotel reception area with a large bridge mural, a reception desk, and a snack bar.

A hotel room with a desk, a bed, a TV, a sofa, a small table, and a view of the outdoors.

A hotel room with a bed, a desk, a chair, a sofa, a small table, and a TV.

16. Staybridge Suites Scottsdale - Talking Stick by IHG

9.7 km from Mayo Clinic Scottsdale

Gentry

NT$4,954

NT$5,648 total

includes taxes & fees

Oct 1 - Oct 2

A circular fire feature with a stone border, surrounded by a landscaped garden with cacti and shrubs, under a sunset sky.

A modern bar area with seating, a digital menu display, and a beverage refrigerator.

A pool area with lounge chairs and umbrellas, surrounded by buildings with balconies and outdoor seating.

A Courtyard by Marriott hotel with a modern design, featuring a covered entrance and stone pillars.

17. Courtyard Scottsdale Salt River

12.2 km from Mayo Clinic Scottsdale

Karl

NT$4,636

NT$5,284 total

includes taxes & fees

Oct 4 - Oct 5

A spacious lobby with a large seating area, a reception desk, and artwork on the walls.

A spacious lobby with leather armchairs, a patterned rug, and a large metal coffee table.

A buffet counter with various food items, a refrigerator, and a wall-mounted clock.

18. Best Western Plus Scottsdale Thunderbird Suites

Thunderbird Industrial Airpark, 12.1 km from Mayo Clinic Scottsdale

Susan

NT$4,140

NT$4,719 total

includes taxes & fees

Sep 29 - Sep 30

A hotel room with a bed, desk, chair, television, fireplace, and a dining area.

An outdoor patio with a grill, table, and chairs.

A reception area with a counter, two armchairs, and a round table.

A hotel room with a bed, a desk with a TV, a sofa, and a coffee table.

19. Sonesta ES Suites Scottsdale Paradise Valley

14 km from Mayo Clinic Scottsdale

Michael

NT$3,811

NT$4,343 total

includes taxes & fees

Oct 15 - Oct 16

A breakfast bar with a variety of baked goods and a sign indicating fresh baked items.

A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.

A reception area with a blue counter, a television screen, and a modern interior design.

A hotel room with a sofa, a chair, a desk with a television, a lamp, and a framed artwork on the wall.

20. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Ally Marie

NT$4,414

NT$5,031 total

includes taxes & fees

Oct 1 - Oct 2

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very good 1,101 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,019 reviews	View
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale	8.8 Excellent 1,862 reviews	View
Spark by Hilton Fountain Hills Scottsdale	8.8 Excellent 318 reviews	View
Comfort Suites Scottsdale Talking Stick Entertainment District	9.2 Wonderful 2,033 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

ADERO Scottsdale Resort, Autograph Collection

10/10 Excellent

"Any issues that I had were taken into consideration and were fixed right away. Lovely property. Great staff. Would stay again."

Spark by Hilton Fountain Hills Scottsdale

8/10 Good

"Highly recommended for the price you pay"

Inn at Eagle Mountain

8/10 Good

"Great stay! Wish the restaurant and bar were open before dinner time."

Wekopa Casino Resort

10/10 Excellent

"Fantastic! Clean room, comfortable beds, good food, great service"

Hampton Inn & Suites Scottsdale at Talking Stick

10/10 Excellent

"It’s what I usually expect for a Hampton Inn. Clean, cheap, easy quiet. No surprises. The free waffles closed the deal."

Sonesta Simply Suites Phoenix Scottsdale

10/10 Excellent

"The microwave didn't have a rotating plate. There was a coffee pot but no coffee. Only one cup for two people. One bowl, no plates. Therefore, kitchen amenities were incomplete."

Great Wolf Lodge Arizona

10/10 Excellent

"O"

Staybridge Suites Scottsdale - Talking Stick by IHG

10/10 Excellent

"The breakfast was fantastic!!"

Sonesta Select Scottsdale at Mayo Clinic Campus

8/10 Good

"Beds where comfortable, but the air conditioning unit in our room was so loud, my earplugs hardly drowned out the sound"

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 21 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 21 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from NT$2,795

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

4. Spark by Hilton Fountain Hills Scottsdale

5. Comfort Suites Scottsdale Talking Stick Entertainment District

6. Close to Hiking! Family-friendly Mesa Retreat

7. Fountain Park Hotel, BW Signature Collection

8. Wekopa Casino Resort

9. Aiden by Best Western Scottsdale North

10. Talking Stick Resort

11. Home2 Suites by Hilton Mesa Longbow, AZ

12. Holiday Inn Express Scottsdale North by IHG

13. ADERO Scottsdale Resort, Autograph Collection

14. Tru By Hilton Scottsdale Salt River

15. Hampton Inn & Suites Scottsdale at Talking Stick

16. Staybridge Suites Scottsdale - Talking Stick by IHG

17. Courtyard Scottsdale Salt River

18. Best Western Plus Scottsdale Thunderbird Suites

19. Sonesta ES Suites Scottsdale Paradise Valley

20. Holiday Inn & Suites Scottsdale North - Airpark by IHG

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

ADERO Scottsdale Resort, Autograph Collection

Spark by Hilton Fountain Hills Scottsdale

Inn at Eagle Mountain

Wekopa Casino Resort

Hampton Inn & Suites Scottsdale at Talking Stick

Sonesta Simply Suites Phoenix Scottsdale

Great Wolf Lodge Arizona

Staybridge Suites Scottsdale - Talking Stick by IHG

Sonesta Select Scottsdale at Mayo Clinic Campus

Frequently asked questions

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